Generation of HSP60-specific regulatory T cell and effect on atherosclerosis.

abstract：:Cells from the spleen, lymph nodes, and peritoneum of DBA/2 mice bearing a subcutaneous tumor mediate nonspecific suppression of an in vitro antibody response to sheep red blood cells (SRBC) when cocultured with a normal T-cell subset(s). The spleen cells from the tumor-bearing mouse required for the suppression bear ...

journal_title：Cellular immunology

authors： Ingenito GG,Calkins CE

更新日期：1983-07-01 00:00:00

abstract：:Strong delayed-type hypersensitivity (DTH) to Babesia microti was elicited when intraerythrocytic parasites (IEP) were inoculated subcutaneously into the flank of normal mice 6 to 14 days before challenge in the ipsilateral footpad with 10(8) IEP. Intraperitoneal or intravenous administration of antigen did not sensit...

journal_title：Cellular immunology

authors： Ruebush MJ,Troutman EH,Kennedy DA

更新日期：1986-04-01 00:00:00

abstract：:The murine T cell hybridoma line, MBI-1.15, secretes a 17-kDa protein which decreases binding activity of the CD23 molecule for its natural ligand, IgE. This protein, denoted epsilon receptor-modulating protein (epsilon RMP), was previously characterized and shown to be a novel serine protease. The present studies sho...

journal_title：Cellular immunology

authors： Matsushita S,Katz DH

更新日期：1994-02-01 00:00:00

abstract：:The incubation of murine splenocytes in recombinant interleukin 2 (IL-2) gives rise to both lymphokine-activated killer (LAK) cells capable of lysing fresh tumor cells and cells capable of mediating antibody-dependent cellular cytotoxicity (ADCC) in the presence of anti-H2 allosera. A similarity between these two IL-2...

journal_title：Cellular immunology

authors： Eisenthal A,Shiloni E,Rosenberg SA

更新日期：1988-09-01 00:00:00

abstract：:The first step of Ig heavy chain class switch recombination (CSR) is considered to be DNA double strand break (DSB) formation in the two switch (S) regions (S(mu) and downstream S(H)), although the underlying mechanism is unknown. Recently, it has been demonstrated that at least Spo11, a homolog of the novel type II t...

journal_title：Cellular immunology

authors： Tokuyama H,Tokuyama Y

更新日期：2000-05-25 00:00:00

abstract：:The systemic adoptive transfer of activated T cells, derived from tumor-draining lymph nodes (LNs), mediates the regression of established tumors. In this study, the requirement of cell adhesion molecules, CD11a/CD18 (LFA-1), CD54 (ICAM-1), CD49d/CD29 (VLA-4), and CD106 (VCAM-1), for T cell infiltration into tumors an...

journal_title：Cellular immunology

authors： Mukai S,Kagamu H,Shu S,Plautz GE

更新日期：1999-03-15 00:00:00

abstract：:Tiazofurin treatment of K562 leukemia cells in vitro depletes the metabolites of the guanylate biosynthetic pathway, inducing erythroid differentiation, that, in turn, alters the phenotypic profile. As a consequence, K562 cells possibly modify their interaction with immune cells. Here we describe the binding and killi...

journal_title：Cellular immunology

authors： Zamai L,Zauli G,Bavelloni A,Marmiroli S,Cataldi A,Weber G,Vitale M

更新日期：1995-08-01 00:00:00

abstract：:Serum of an autoimmune MRL/Mp-lpr/lpr (MRL/l) mouse supported the proliferation of interleukin 3 (IL-3)-dependent cell line, FDC-P2. This IL-3-like activity initially appeared at 1 month of age and increased with age. Females showed higher titers than did males. MRL/Mp-+/+ mouse sera also exhibited such activity, thou...

journal_title：Cellular immunology

authors： Tasaka K,Sakihama T,Shirakura-Shibata Y,Matsuda S,Nakajima Y

更新日期：1989-07-01 00:00:00

abstract：:The murine B-cell differentiation antigen Lyb-2 has been shown to be involved in B-lymphocyte activation and has been postulated by some to be related to a receptor for B-cell stimulatory factor I (BSF-1) (H. Yakura et al., J. Immunol. 137, 1475, 1986). Here we have demonstrated that monoclonal antibody (mAB) to Lyb-2...

journal_title：Cellular immunology

authors： Subbarao B,Morris J,Baluyut AR

更新日期：1988-04-01 00:00:00

abstract：:Aging diminishes the amount of phosphotyrosine in the CD3zeta chains of resting and activated mouse CD4 T cells by about threefold and might therefore be expected to a corresponding decline in Zap-70 association with CD3zeta and in Zap-70 kinase function in CD3zeta complexes. We show here that aging leads, unexpectedl...

journal_title：Cellular immunology

authors： Garcia GG,Miller RA

更新日期：1998-12-15 00:00:00

abstract：:We describe here a novel real-time cell tracking system which can measure cell migration routes under cell culture condition. This system includes a mini incubator which controls temperature and CO(2) gas flow and a PDMS (polydimethylsiloxane) chip for chemotaxis measurement. The main differences from previous ones ar...

journal_title：Cellular immunology

authors： Kwak YH,Hong SM,Park SS

更新日期：2010-01-01 00:00:00

abstract：:Thymic (T) or bursal (B) lymphocytes from chicks sensitized to Mycobacterium tuberculosis produce an avian lymphocyte inhibitory factor (LyIF). The physiochemical properties of both T and B LyIF were established by ultrafiltration which yielded four fractions with molecular weight ranges of greater than 100,000; 50,00...

journal_title：Cellular immunology

authors： Martin DE,Glick B

更新日期：1983-07-15 00:00:00

abstract：:Experimental autoimmune thyroiditis is induced in mice by immunization with thyroglobulin emulsified in Freund's complete adjuvant. The disease is characterized both by thyroid infiltration with mononuclear cells and by circulating thyroglobulin antibodies. The magnitude of the thyroid infiltration and the titer of th...

journal_title：Cellular immunology

authors： Vladutiu AO,Steinman L

更新日期：1987-10-01 00:00:00

abstract：:The role of class II antigens for B-cell activation was analyzed using purified human B cells and anti-class II monoclonal antibodies. The stimulation of purified B cells with Staphylococcus aureus Cowan I induced proliferation and differentiation into immunoglobulin-producing cells in the presence of interleukin-1 an...

journal_title：Cellular immunology

authors： Tanaka Y,Shirakawa F,Ota T,Suzuki H,Eto S,Yamashita U

更新日期：1988-04-01 00:00:00

abstract：:Murine bone marrow-derived cultured mast cells (BMMCs) are most widely used in in vitro experiments for evaluation of mast cell functions. The present study has shown that cell preparation procedure, i.e., cell collection by centrifugation and the subsequent adjustment and culture of cell density at the desired concen...

journal_title：Cellular immunology

authors： Murakami M,Ikeda T,Nishino Y,Funaba M

更新日期：2005-11-01 00:00:00

abstract：:As fascinating a molecule as it can potentially get, nuclear factor-κB (NF-κB), a regulatory transcription factor, is as intriguing. NF-κB is a dimeric complex that controls the transcription of essential genes. NF-κB is involved in a variety of responses that play a pivotal role in regulating the immune response to i...

journal_title：Cellular immunology

authors： Haddad JJ,Abdel-Karim NE

更新日期：2011-01-01 00:00:00

abstract：:A low-virulence, agerminative strain of Candida albicans (PCA-2) is able to confer a high degree of nonspecific protection against subsequent challenge with highly virulent microorganisms in mice. In an attempt to better define the effect of PCA-2 vaccination on the immune system and the nature of the mechanisms invol...

journal_title：Cellular immunology

authors： Vecchiarelli A,Cenci E,Puliti M,Blasi E,Puccetti P,Cassone A,Bistoni F

更新日期：1989-12-01 00:00:00

abstract：:Cyclosporin A (CsA) was tested for its modulatory effects on the mIgM-mediated signaling of G0*-associated increases in class II MHC expression, G1-related RNA synthesis, and S phase-related DNA synthesis in human B cells. While CsA at concentrations as low as 10-100 ng/ml could completely ablate anti-IgM-induced DNA ...

journal_title：Cellular immunology

authors： Mongini PK,Blessinger CA,Dalton JP,Seki T

更新日期：1992-04-01 00:00:00

abstract：:A variety of arachidonic acid metabolites possess the ability to modulate immune cell function. Various inhibitors of arachidonic acid metabolism were compared with regard to their effects on T-suppressor (Ts) cell function. Using staphylococcal enterotoxin B (SEB) to activate Lyt-2+ Ts cells, it was shown that indome...

journal_title：Cellular immunology

authors： Donnelly RP,Rogers TJ

更新日期：1983-10-01 00:00:00

abstract：:Rotavirus infection of permissive cells is a multi-step process that requires interaction with several cell surface receptors. Integrins alpha2beta1, alpha4beta1, alphaXbeta2, and alphavbeta3 are involved in the attachment and entry into permissive cells for many rotavirus strains. However, possible roles of known par...

journal_title：Cellular immunology

authors： Halasz P,Fleming FE,Coulson BS

更新日期：2005-07-01 00:00:00

abstract：:The development of B cell tolerance is believed to involve negative signaling to B cells derived from the binding of antigen to the B cell surface immunoglobulin. B cell lines that receive negative signals may provide useful models for studying the mechanisms of B cell tolerance. We have established a human B lymphoma...

journal_title：Cellular immunology

authors： Komada Y,Zhang XL,Zhou YW,Tanaka S,Higashigawa M,Ido M,Sakurai M

更新日期：1994-12-01 00:00:00

abstract：:The fine specificity of anti-Glu60Ala30Tyr10 (GAT) and anti-Glu60Ala40 (GA) proliferating cells was studied. T cells primed with GAT proliferate both to GAT and GA and GA-primed T cells proliferate also to GA and GAT. This cross-reactivity was unexpected given the results previously reported on the fine specificity of...

journal_title：Cellular immunology

authors： Gougeon ML,Bismuth G,Leclercq L,Somme G,Thèze J

更新日期：1983-01-01 00:00:00

abstract：:The adoptive transfer of tumor-reactive T lymphocytes has recently been demonstrated to be an effective means for mediating the regression of experimental intracranial fibrosarcomas. In this study, mice bearing syngeneic intracranial GL261 gliomas were cured by the combination of sublethal whole body irradiation follo...

journal_title：Cellular immunology

authors： Plautz GE,Touhalisky JE,Shu S

更新日期：1997-06-15 00:00:00

abstract：:Mice that received a sublethal, intraperitoneal dose of viable Listeria monocytogenes, virulent strain 10403, exhibited a systemic increase in natural killer (NK) activity. The kinetics of the response differed with respect to the various effector cell populations analyzed. Resident peritoneal cells and peripheral blo...

journal_title：Cellular immunology

authors： Kearns RJ,Leu RW

更新日期：1984-04-01 00:00:00

abstract：:This study examined the characteristics of functional anergy of natural killer cells (NK) following their interaction with target cells. Purified NK cells were cocultured with K562 for 15 min or 4 hr to allow for binding of targets to NK cells. The resulting NK-target conjugates were then dissociated by EDTA, and the ...

journal_title：Cellular immunology

authors： Jewett A,Bonavida B

更新日期：1995-01-01 00:00:00

abstract：:ErbB-2 is ubiquitinated and degraded when dissociated from its membrane chaperone or bound by specific antibody. Reagents which induce such degradation have demonstrated antitumor activity and may impact ErbB-2 immunogenicity. To further understand ErbB-2 degradation and immunogenicity, a glycine-alanine repeat (GAr) ...

journal_title：Cellular immunology

authors： Piechocki MP,Pilon SA,Kelly C,Wei WZ

更新日期：2001-09-15 00:00:00

abstract：:At concentrations as low as 10(-7) M, the cardiotonic glycosteroid ouabain, a specific inhibitor of the membrane Na+, K+-ATPase, is known to inhibit in vitro human lymphocyte proliferation produced in mixed lymphocyte cultures or induced by various stimulating agents (PHA, Con A, PWM, soluble antigens), while mouse ly...

journal_title：Cellular immunology

authors： Dornand J,Favero J,Bonnafous JC,Mani JC

更新日期：1984-02-01 00:00:00

abstract：:The many signals that control the progress of various immune responses to both foreign and self antigens can be divided into no less than three major groups. The first group is the initial positive stimulus, associated with activation events through antigen receptors and their associated proteins. These signals launch...

journal_title：Cellular immunology

authors： Sinclair NR

更新日期：1990-10-01 00:00:00

abstract：:The primary objective of this study was to determine whether the n-3 PUFA-mediated changes in host response to a Listeria monocytogenes infection (e.g., cytokine production and bacterial clearance) were dependent upon neutrophils. Balb/c mice were fed one of two semi-purified diets that contained either 0 or 41 g of n...

journal_title：Cellular immunology

authors： Fritsche K,Irons R,Pompos L,Janes J,Zheng Z,Brown C

更新日期：2005-05-01 00:00:00

abstract：:In previous studies, the murine SaI (A/J derived, KkDd) sarcoma was transfected with the allogeneic MHC class I H-2Kb gene, and expressed high levels of H-2Kb antigen. Contrary to expectations, the tumor cells expressing the alloantigen (SKB3.1M tumor cells) were not rejected by autologous A/J mice. Because these resu...

journal_title：Cellular immunology

authors： Cole GA,Ostrand-Rosenberg S

更新日期：1991-05-01 00:00:00