Abstract:
BACKGROUND:To describe the clinical characteristics of active ocular toxoplasmosis in a large population of Turkish patients. METHODS:A retrospective study of 109 consecutive patients with active ocular toxoplasmosis seen at the Department of Ophthalmology, Istanbul Faculty of Medicine, from 1995 to 2005. RESULTS:Fifty-seven patients were female and 52 were male. The mean age at presentation was 25.7 +/- 6.8 years. All patients had positive serum anti-toxoplasma IgG antibodies, but negative IgM antibodies. Preexisting retinochoroidal scars were found in 90 (83%) patients. Central active lesions were significantly more common in eyes without previous involvement than in eyes with preexisting scars (97% vs. 59%). Active lesions were adjacent to a scar in 60 (78.9%) of 76 eyes with preexisting scars. The most common accompanying signs were vitritis (100%), anterior uveitis (49.5%), and periphlebitis (33%). All patients received antiparasitic treatment. Systemic corticosteroids were used in 86% of the patients. Kaplan-Meier survival analysis estimated the cumulative risk of recurrence as 74% at 42 months of follow-up. In 29 (80.5%) of 36 recurrent attacks, active lesions were associated with the scars of the most recent attack. After the resolution of the presenting attack, visual acuity was better than 0.5 in 90%, between 0.1 and 0.5 in 5%, and less than 0.1 in 5% of eyes. Further decrease in visual acuity occurred in only two eyes during our follow-up. CONCLUSIONS:Most of the patients with active ocular toxoplasmosis have asymptomatic retinochoroidal scars. Proximity of active lesions to the scars, and especially to those of the most recent episode, may have implications for treatment. Although the recurrence risk is high, the visual prognosis is good in most patients with typical ocular toxoplasmosis.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Tugal-Tutkun I,Corum I,Otük B,Urgancioglu Mdoi
10.1007/s10792-007-9047-8subject
Has Abstractpub_date
2005-12-01 00:00:00pages
221-8issue
6eissn
0165-5701issn
1573-2630journal_volume
26pub_type
杂志文章abstract:BACKGROUND:To evaluate the preliminary effects of treating the half of high latent hyperopia on refractive and visual outcomes of femtosecond laser-assisted in situ keratomileusis (LASIK) in young subjects with hyperopia. METHODS:This non-randomized comparative study includes 120 eyes of 60 subjects who underwent femt...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01421-5
更新日期:2020-09-01 00:00:00
abstract::Oximetry may be useful for understanding pathologies of the eye. We use a prototype scanning laser ophthalmoscope capable of simultaneous multiple wavelength imaging to record fundus images. The system is run under non-confocal conditions in using slit apertures with a width of up to 600 microm. The laser lines launch...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1014406831412
更新日期:2001-01-01 00:00:00
abstract::Using a direct immunofluorescent technique and monoclonal antibody, chlamydia trachomatis was detected in the conjunctival smears of 13 out of 47 patients presenting with conjunctivitis or keratoconjunctivitis (an incidence of 28%). Two patients presented with acute symptoms of few days duration, whereas the condition...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00133933
更新日期:1988-01-01 00:00:00
abstract::Risk factors for corneal transplantation failure include both immunologic factors, such as graft rejection, corneal neovascularization, and peripheral anterior synechiae, as well as non-immunologic factors, such as ocular surface disorders (OSD) and glaucoma. This review highlights the necessity of having healthy ocul...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-007-9127-9
更新日期:2008-06-01 00:00:00
abstract::17 patients with intraretinal magnetic foreign bodies and vitreous hemorrhage are reported. 15 patients underwent a primary surgical repair consisting of a watertight wound closure and removal of the already swelling cataractous lens in 5 cases. All patients had vitrectomy during the second postinjury week. The foreig...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02279868
更新日期:1989-09-01 00:00:00
abstract:AIM:To evaluate the effect of acute anaerobic exercise on macular perfusion measured by swept-source optical coherence tomography angiography (SS-OCTA) in young football players. MATERIALS AND METHODS:Football players with ages between 18 and 20 years were included into the study. After a detailed ophthalmological exa...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01303-w
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Our purpose is to describe a safe and easy technique for the removal of the BrightOcular cosmetic iris implants. Our technique involves cutting the implant into five parts rather than removal as a whole with less intraocular manipulation and no rotation of the implant. METHODS:We have used this technique in tw...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01328-1
更新日期:2020-06-01 00:00:00
abstract::In the original publication, first line of methods under the Abstract section was published incorrectly. ...
journal_title:International ophthalmology
pub_type: 已发布勘误
doi:10.1007/s10792-020-01327-2
更新日期:2020-04-01 00:00:00
abstract::The purpose of this study is to investigate whether subconjunctival and/or intrastromal Bevacizumab injections could help to prevent graft failure in high-risk keratoplasties. Twenty seven eyes of 27 patients, affected by high immune rejection risk and corneal neovascularization, were involved in this prospective inte...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-9938-4
更新日期:2015-04-01 00:00:00
abstract::A 22-year-old male presented to us with complaints of sudden painful loss of vision in left eye 10 days ago along with inward deviation of the left eye. Best-corrected visual acuity (BCVA) in right eye was 20/20 and 20/50 in left eye. Left eye showed limitation of abduction, a relative afferent pupillary defect, norma...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0910-6
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:Aromatase inhibitors (anastrozole, letrozole) and selective estrogen receptor modulators (tamoxifen) are widely used as adjuvant hormonal therapy in women with hormone receptor-positive breast cancer. We aimed to evaluate the effects of oral adjuvant hormonotherapy on tear functions in patients with breast canc...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01384-7
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS:Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group wa...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0368-3
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The surgical management of macular holes has been a subject of controversy in recent years. Various techniques such as vitrectomy, membrane peeling, and gas tamponade with or without transforming growth factor-beta 2, and recently the use of autologous platelets have produced closure rates from 58% to 96%, d...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1023/a:1005866002930
更新日期:1997-01-01 00:00:00
abstract::Out of 49 patients diagnosed as having Stargardt's disease that have been clinically reviewed, 22 of these cases have been followed for a period up to 13 years. The cases have been studied in three subgroups, according to their fundus appearance. Patients from group I were those whose lesions were confined to the macu...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00137651
更新日期:1985-11-01 00:00:00
abstract:PURPOSE:The objective of this study is to examine the morphometry of the lacrimal drainage system with reference to bony landmarks in the vicinity. METHODS:Twenty midsaggitalized heads obtained from sixteen preserved cadavers were studied. Measurements involved detailed morphometry of anterior and posterior lacrimal c...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0753-6
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To gain an insight into the manufacturing and fitting of artificial eyes in children and potential improvements to the process. METHOD:An online qualitative survey was distributed to 39 ocularists/prosthetists in Europe and Canada. Participants were recruited through purposive sampling, specifically maximum va...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-016-0383-4
更新日期:2017-10-01 00:00:00
abstract::We report the immunopathology and histopathology of a patient with Terson syndrome. The design was an observational case-report. Histopathology and immunohistochemical staining for endoglin (CD105) of an eye from a patient with subarachnoid haemorrhage and Terson syndrome was performed. Immunohistology revealed high p...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-010-9343-6
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01521-2
更新日期:2020-12-01 00:00:00
abstract::The effect of therapeutic ultrasound for the treatment of refractory glaucoma was evaluated in 44 patients by comparing average IOP curves measured before and 3-4 months after treatment. The insonification regime was standardized and the glaucoma medication in each individual patient was unchanged during IOP curve mea...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918000
更新日期:1992-09-01 00:00:00
abstract:PURPOSE:To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. METHODS:A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were perfor...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9111-4
更新日期:2008-04-01 00:00:00
abstract::Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00159835
更新日期:1986-05-01 00:00:00
abstract::A 71-year-old man presented with a large disciform scar in the right eye and hard (nodular) as well as soft (granular) drusen scattered throughout the posterior pole of the left eye. A large serous pigment epithelial detachment was evident in the drusen area of the left fundus. Six months later a tear of the retinal p...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00139344
更新日期:1987-06-01 00:00:00
abstract:PURPOSE:The aim of this pilot study was to evaluate a new semiautomatic procedure to assess in vivo changes in the crystalline lens and ciliary muscle during accommodation. METHODS:A total of 14 subjects were divided into two groups, young (aged between 20 and 25 years) and adult (aged between 35 and 40 years), and me...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0752-7
更新日期:2018-12-01 00:00:00
abstract::To report a patient with optic disc pit who showed decreased inner diameter of the optic disc pit along with resolution of recurrent macular detachment after pars plana vitrectomy. Pneumatic retinopexy and peripapillary laser photocoagulation was performed in a 28-year-old female with optic disc pit and serous macular...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9656-8
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To evaluate the accuracy of intraocular lens (IOL) power calculation in relation to optical biometry devices and refraction types. METHODS:Patients undergoing cataract phacoemulsification and insertion of the MX60 IOL were enrolled. Optical biometric measurements were performed with both IOLMaster 700 and Lens...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01355-y
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:A case report of recurrent unilateral granulomatous iridocyclitis with ocular hypertension without retinitis caused by cytomegalovirus (CMV) in an immunocompetent patient. METHODS:Aqueous humor was analysed by multiplex PCR to detect viral DNA, and real-time PCR was used to evaluate virus copies before and ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9090-5
更新日期:2007-12-01 00:00:00
abstract::Retinal astrocytic hamartomas are benign tumors of the retinal nerve fiber layer (NFL) that may be found in association with tuberous sclerosis (TS). We describe the spectral-domain optical coherence tomography (SD-OCT) features of type 1 astrocytic hamartomas in a child with TS that may aid in the diagnosis and follo...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9586-5
更新日期:2012-10-01 00:00:00
abstract::We made two trips to Cuba, as part of an invited international delegation, to investigate an epidemic of optic neuropathy-induced blindness. We worked closely with Cuban scientists and clinicians in their efforts to understand and then deal with 50,000 cases of blindness and an entire population at risk. This gave an ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00930318
更新日期:1994-01-01 00:00:00
abstract::To evaluate the role of brimonidine (BMD), an alpha-2 agonist, in the management of clinically significant macular edema (CSME) in diabetic maculopathy with ischemic changes. A prospective, randomized controlled trial including 30 eyes of 30 metabolically stable diabetic patients with CSME showing fundus fluorescein a...
journal_title:International ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10792-013-9871-y
更新日期:2014-08-01 00:00:00
abstract::Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon disease most frequently occurring in the head and neck region. It occurs in all races. In spite of a clear distinction between ALHE and Kimura's disease on histological grounds for almost 20 years now, confusion and misdiagnosis still exist to date. Thr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9741-7
更新日期:2014-02-01 00:00:00