Cloning of a rat-specific long PCP4/PEP19 isoform.

Abstract:

:We report the identification of a cDNA that encodes a putative protein of 94 amino acids and expected molecular weight of 10.7 kDa, the C-terminal half of which is identical to that of PEP19, a small, brain-specific protein involved in Ca++/calmodulin signaling. The novel rat-specific protein, tentatively named long PEP19 isoform (LPI), is the product of alternative splicing of the rat PCP4 gene encoding PEP19. We found that antibodies raised against the first 13 N-terminal amino acids of LPI, not present in PEP19, recognize a protein enriched in the developing rat brain.

journal_name

Int J Mol Med

authors

Sala A,Scaturro M,Proia P,Schiera G,Balistreri E,Aflalo-Rattenbach R,Créau N,Di Liegro I

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

501-9

issue

3

eissn

1107-3756

issn

1791-244X

journal_volume

19

pub_type

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