Abstract:
:Despite the presence of a number of anecdotal reports in the mountaineering literature, mucociliary dysfunction at high altitude has received little scientific attention. However, the dry, cold, thin air at high altitude has the potential to undermine normal mucociliary function. This seems increasingly likely in mountaineers who also experience dehydration, nasal obstruction, and extremes of aerobic respiration when climbing in such environments. These factors may result in a number of clinical conditions that range from sore throats and coughs commonly seen at altitude to rarer cases of bronchiolar collapse and lung atelectasis. The purpose of this review is to discuss the etiology of mucociliary dysfunction at altitude and outline a number of potential solutions to the problems this phenomenon presents.
journal_name
Wilderness Environ Medjournal_title
Wilderness & environmental medicineauthors
Rodway GW,Windsor JSdoi
10.1580/pr36-05.1subject
Has Abstractpub_date
2006-01-01 00:00:00pages
271-5issue
4eissn
1080-6032issn
1545-1534pii
S1080-6032(06)70332-5journal_volume
17pub_type
杂志文章,评审abstract::Exposure to and consumption of brackish water are associated with an elevated risk of infection, hypernatremia, and hypothermia. Minimal data exist to support the diagnosis and treatment of patients with long-term brackish water exposure. We present a case of a patient who spent 5 to 10 d semisubmerged in the Elizabet...
journal_title:Wilderness & environmental medicine
pub_type:
doi:10.1016/j.wem.2020.04.003
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to test the hypothesis that polymorphisms in the endothelial PAS domain protein 1 (EPAS1) gene are associated with the susceptibility to high altitude pulmonary edema (HAPE) in Han Chinese. METHODS:This study enrolled 153 HAPE patients (HAPE-p), matched with Han Chinese resistan...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2013.05.006
更新日期:2013-12-01 00:00:00
abstract::Remote extended expeditions often support scientific research and commercial resource exploration or extraction in hostile environments. Medical support for these expeditions is inherently complex and requires in-depth planning. To be successful, this planning must include substantial input from clinicians with experi...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2013.05.005
更新日期:2013-12-01 00:00:00
abstract:INTRODUCTION:To compare the effectiveness of a molded fleece jacket with that of a standard cervical collar at limiting movement of the cervical spine in 3 different directions. METHODS:This is a prospective study using 24 healthy volunteers to measure cervical flexion/extension, rotation, and lateral flexion with bot...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2019.07.002
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Minimal data exist regarding the activity, membership, training, and medical oversight of search and rescue (SAR) teams. OBJECTIVE:Our objective was to describe these characteristics in the Intermountain West SAR organizations. METHODS:A contact list was generated and electronic surveys were sent to SAR of...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2013.08.002
更新日期:2013-12-01 00:00:00
abstract::A hydatid cyst is a parasitic disease caused by the tapeworm Echinococcus granulosus. It is endemic in many areas, including New Zealand, Australia, and the Mediterranean region. Pulmonary hydatid disease can be diagnosed incidentally in asymptomatic patients or may cause symptoms such as cough, chest pain, dyspnea, f...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/07-WEME-CR-1561.1
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:The presence of coliform bacteria indicates a watershed risk for harboring microbes capable of causing human disease. We hypothesized that water from watersheds that have different human- or animal-use patterns would have differing risks for the presence of coliform bacteria. METHODS; Water was collected in w...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/pr05-05.1
更新日期:2006-04-01 00:00:00
abstract::Hematotoxic snake bite is a leading cause of mortality in South India. However, it is rare for the emergency physician to encounter a patient with trauma associated with snakebite. Management of such a patient differs substantially from the routine management of either a trauma patient or a snakebite victim. A 59-y-ol...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2020.08.003
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To determine the knowledge, beliefs, and behavior of local residents and visitors to North Queensland who may be at risk of contact with "Irukandji" jellyfish. METHODS:Structured interviews were conducted with 208 ferry passengers (92.9% response) traveling between Magnetic Island and Townsville (19 degrees ...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/1080-6032(2004)015[0004:rkpabo]2.0.co;2
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:Scorpionism is an endemic public health problem in Jordan encountered by health providers in all parts of the country. This study updates epidemiological data on scorpion sting encounters in Jordan. METHODS:Data on scorpion sting encounters were obtained from government and military hospitals around the coun...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2017.05.003
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To compare altitude responses of 2 ultraendurance athletes and 2 nonathletes during a 2-week expedition on Denali (Mount McKinley). METHODS:The severity of acute mountain sickness (AMS) symptoms (Lake Louise AMS guidelines) and pulmonary function parameters (forced vital capacity, forced expiratory volume in...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/1080-6032(2005)16[198:prouaa]2.0.co;2
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:In low-income countries, snakebites are frequently managed in rural areas in health centers with severely constrained resources. Many healthcare providers in these settings have limited access to the numerous and relatively expensive laboratory studies used to diagnose envenomation. The relatively simple and...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2013.08.001
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To describe search and rescue activity performed by the National Park Service (NPS) on Denali, the highest point in North America. METHODS:A retrospective review was performed of all search and rescue (SAR) operations by the NPS from 1990 to 2008. Descriptive analysis was used to describe these cases as well...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2009.12.024
更新日期:2010-06-01 00:00:00
abstract::We present 3 cases of severe hyponatremia occurring on a commercially guided river rafting trip on the Colorado River in Grand Canyon National Park. All 3 women appeared to have been overhydrating because of concern about dehydration and required evacuation within 24 hours of each other after the staggered onset of sy...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2014.08.007
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Our objective was to determine the incidence of acute mountain sickness (AMS) and the cardiorespiratory responses, in children and their parents, after rapid ascent to 3500 m. The sample population was composed of children and their parents who ascended within 24 hours from Arica (sea level) to Putre (3500 m)...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/06-WEME-BR-084.1
更新日期:2008-01-01 00:00:00
abstract::Exercise-associated hyponatremia (EAH) is defined by a serum or plasma sodium concentration below the normal reference range of 135 mmol/L that occurs during or up to 24 hours after prolonged physical activity. It is reported to occur in individual physical activities or during organized endurance events conducted in ...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章,实务指引
doi:10.1016/j.wem.2014.08.009
更新日期:2014-12-01 00:00:00
abstract::We describe a patient with missed traumatic pneumothorax due to penetrating neck injury that was presumably caused by a stingray while diving. The barb can result in significant injuries to deep structures and organs despite a deceptively small entrance wound. This case underscores the importance of performing a thoro...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2017.02.006
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To examine circulating hormonal responses in men competing in the Western States Endurance Run (WSER, June 23 to 24, 2012): a 161-km trail run that starts in Squaw Valley, CA, and concludes in Auburn, CA. METHODS:We examined 12 men who completed the WSER. Blood samples were obtained the morning before the ra...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2014.03.013
更新日期:2014-09-01 00:00:00
abstract::During historic, as well as more recent, conflicts, most combat casualties who die from their injuries do so in the prehospital setting. Although many of the injuries incurred by these casualties are nonsurvivable, a number of injuries are still potentially survivable. Of those injuries that are potentially survivable...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章,评审
doi:10.1016/j.wem.2016.11.007
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To measure afterdrop and rewarming in subjects placed in a hypothermia wrap immediately after extrication from 60 minutes of snow burial. METHODS:We measured esophageal core body temperature (Tes) in 6 subjects buried in compacted snow (mean density 39%) for up to 60 minutes at an altitude of 2450 m while br...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2010.06.007
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to review the patient characteristics and management of 56 cases of high altitude pulmonary edema at the Pheriche Himalayan Rescue Association Medical Aid Post, and to measure the use of medications in addition to descent and oxygen. METHODS:In a retrospective case series, we re...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2012.07.004
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Olfactory function, a cognitive impairment biomarker, was evaluated in mountain ultramarathon (MUM) runners during the Tor des Géants race (332.5 km with an overall altitude gain of 24,000 m; altitude range 330-3296 m above the sea). METHODS:An Odor Identification Test was administered before (T0; n = 53), a...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2015.11.013
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the effects of gender and menstrual cycle on the percent of carbohydrate (CHO) utilized during cold water immersion (20 degrees C). Previous research has suggested that males and females utilize CHO differently during submaximal exercise. This study examined whether t...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/1080-6032(2000)011[0005:teogam]2.3.co;2
更新日期:2000-04-01 00:00:00
abstract::Injuries caused by wild boar attacks are rare. A 34-year-old male shepherd sustained injuries caused by a wild boar attack, and was brought to our emergency department. The patient had 2 skin and deep tissue lacerations on the posterior aspect of his thigh. Herein, we discuss the clinical management of a wild boar bit...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2011.06.005
更新日期:2011-09-01 00:00:00
abstract::We experienced a case involving prolonged cardiopulmonary resuscitation (CPR) during cardiac arrest on Mt. Fuji (3776 m), demanding lengthy exertion by the rescuers performing CPR. Considering the effects of exertion on the rescuers, we examined their percutaneous arterial oxygen saturation during simulated CPR and co...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2019.10.008
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The study aimed to examine the physiological responses to acute normobaric hypoxia during an intermittent walking protocol. METHODS:Twelve active healthy male participants completed a 125-minute test that involved rest and walking (50% VO(2max)) during normoxic (20.93%O(2)) and 2 hypoxic conditions (14%O(2) ...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1580/07-WEME-OR-143.1
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Skiing and snowboarding are popular activities that involve high kinetic energies, often at altitude, and injuries are common. As a portable imaging modality, ultrasound may be a useful adjunct for mountainside clinics. This review briefly discusses skier and snowboarder injury profiles and focuses on the ro...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章,评审
doi:10.1016/j.wem.2012.03.012
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:Antarctic expeditioners face extremes of environmental conditions along with isolation which affect normal human activity at a polar station. Diets of polar expeditioners consist of products that have been kept in storage for more than a year. Processing and preservation adversely affect the nutritive value o...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1580/06-WEME-OR-004R3.1
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:The utility of digital intubation, especially in an austere environment with limited equipment, has been previously described. However, evidence supporting best practices for its technique is limited. We seek to quantify the time to intubation and the rate of successful placement of the tube for digital in...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2018.11.006
更新日期:2019-03-01 00:00:00
abstract::Although catfish are found worldwide and commonly consumed in the southern United States, fatal infections from catfish are rare. Edwardsiella tarda is a bacterium known to cause gastrointestinal distress most commonly, but extraintestinal infections are a rarely considered danger for those acquiring, preparing, and c...
journal_title:Wilderness & environmental medicine
pub_type: 杂志文章
doi:10.1016/j.wem.2019.04.004
更新日期:2019-09-01 00:00:00