Preparing the way: fungal motors in microtubule organization.

Abstract:

:Fungal growth, development and pathogenicity require hyphal tip growth, which is supported by polar exocytosis at the expanding growth region. It is assumed that molecular motors transport growth supplies along the fibrous elements of the cytoskeleton, such as microtubules, to the hyphal apex. Recent advances in live-cell imaging of fungi revealed additional roles for motors in organizing their own tracks. These unexpected roles of the molecular motors are modifying microtubule dynamics directly, targeting stability-determining factors to microtubule plus ends, and transporting and arranging already-assembled microtubules.

journal_name

Trends Microbiol

journal_title

Trends in microbiology

authors

Steinberg G

doi

10.1016/j.tim.2006.11.007

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

14-21

issue

1

eissn

0966-842X

issn

1878-4380

pii

S0966-842X(06)00272-1

journal_volume

15

pub_type

杂志文章
  • The fungal genus Cochliobolus and toxin-mediated plant disease.

    abstract::Several times in this century, new and sometimes devastating diseases of cereal crops, caused by fungi in the genus Cochliobolus, have suddenly appeared. In many fungal diseases of plants the factors required for pathogenicity are unknown; in contrast, the key elements in each of several Cochliobolus diseases are know...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/0966-842x(93)90019-n

    authors: Panaccione DG

    更新日期:1993-04-01 00:00:00

  • Molecular Evolution of Human Coronavirus Genomes.

    abstract::Human coronaviruses (HCoVs), including SARS-CoV and MERS-CoV, are zoonotic pathogens that originated in wild animals. HCoVs have large genomes that encode a fixed array of structural and nonstructural components, as well as a variety of accessory proteins that differ in number and sequence even among closely related C...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2016.09.001

    authors: Forni D,Cagliani R,Clerici M,Sironi M

    更新日期:2017-01-01 00:00:00

  • Archaeal CRISPR-based immune systems: exchangeable functional modules.

    abstract::CRISPR (clustered regularly interspaced short palindromic repeats)-based immune systems are essentially modular with three primary functions: the excision and integration of new spacers, the processing of CRISPR transcripts to yield mature CRISPR RNAs (crRNAs), and the targeting and cleavage of foreign nucleic acid. T...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2011.08.002

    authors: Garrett RA,Vestergaard G,Shah SA

    更新日期:2011-11-01 00:00:00

  • Kinase-phosphatase competition regulates Bacillus subtilis development.

    abstract::The major regulator of sporulation initiation in Bacillus subtilis is the phosphorelay, a multicomponent signal transduction system. A myriad of signals, both positive and negative, from the environment, cell cycle and metabolism is received and interpreted by the phosphorelay and integrated through the opposing activ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(98)01350-x

    authors: Perego M

    更新日期:1998-09-01 00:00:00

  • RTX Adhesins are Key Bacterial Surface Megaproteins in the Formation of Biofilms.

    abstract::Gram-negative bacteria produce repeats-in-toxin adhesion proteins (RTX adhesins) to facilitate microbial adhesion. These large, multidomain proteins share a common architecture comprised of four regions. First to emerge from the bacterium, C terminal end leading, is the RTX export sequence that directs the protein thr...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2018.12.003

    authors: Guo S,Vance TDR,Stevens CA,Voets I,Davies PL

    更新日期:2019-05-01 00:00:00

  • Do bacteria need to communicate with each other for growth?

    abstract::It is usually assumed that most prokaryotes, when given appropriate nutrients, can grow and divide in the absence of other cells of the same species. However, recent studies have suggested that, for growth, prokaryotes need to communicate with each other using signalling molecules, and a variety of 'eukaryotic' hormon...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/0966-842X(96)10035-4

    authors: Kaprelyants AS,Kell DB

    更新日期:1996-06-01 00:00:00

  • Another brick in the wall.

    abstract::The existence of a peptidoglycan cell wall in chlamydiae has been debated for several years. Several studies suggest that these organisms synthesize a cell wall, but some of the components and biosynthetic machinery seem to be missing and a bona fide cell wall has yet to be described. A recent study has revealed that ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2007.02.003

    authors: Pavelka MS Jr

    更新日期:2007-04-01 00:00:00

  • Emerging therapies for multidrug resistant Acinetobacter baumannii.

    abstract::The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics that retain activity against this pathogen. For this reason, the development of novel prevention and treatment strategies for infections caused by A. baumannii is necessary. Several studies ha...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2012.12.002

    authors: García-Quintanilla M,Pulido MR,López-Rojas R,Pachón J,McConnell MJ

    更新日期:2013-03-01 00:00:00

  • Type III secretion à la Chlamydia.

    abstract::Type III secretion (T3S) is a mechanism that is central to the biology of the Chlamydiaceae and many other pathogens whose virulence depends on the translocation of toxic effector proteins to cytosolic targets within infected eukaryotic cells. Biomathematical simulations, using a previously described model of contact-...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2007.04.005

    authors: Peters J,Wilson DP,Myers G,Timms P,Bavoil PM

    更新日期:2007-06-01 00:00:00

  • Maximum shields: the assembly and function of the bacterial spore coat.

    abstract::Spores produced by bacilli and clostridia are surrounded by a multilayered protein shell called the coat. As the armor-like appearance of the coat suggests, this structure, along with others within the spore, confers the remarkable resistance properties that make Bacillus anthracis spores such potent biological weapon...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(02)02373-9

    authors: Driks A

    更新日期:2002-06-01 00:00:00

  • Processing and export of peptide pheromones and bacteriocins in Gram-negative bacteria.

    abstract::Cell-density-dependent gene expression is widespread in bacteria and is mediated by extracellular communication molecules. Gram-negative bacteria often use N-acyl homoserine lactones, whereas cell-cell signaling in Gram-positive bacteria is accomplished using post-translationally processed peptide pheromones. In many ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(01)01979-5

    authors: Michiels J,Dirix G,Vanderleyden J,Xi C

    更新日期:2001-04-01 00:00:00

  • Phage Therapy: Going Temperate?

    abstract::Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bacterial virulence, for example, by promoting antibiotic...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2018.10.008

    authors: Monteiro R,Pires DP,Costa AR,Azeredo J

    更新日期:2019-04-01 00:00:00

  • Lipid chemotaxis and signal transduction in Myxococcus xanthus.

    abstract::The lipid phosphatidylethanolamine (PE) is the first chemoattractant to be described for a surface-motile bacterium. In Myxococcus xanthus, the specific activity of PE is determined by its fatty acid components. Two active species have been identified: dilauroyl PE and dioleoyl PE. Excitation to dilauroyl PE requires ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(01)01948-5

    authors: Kearns DB,Shimkets LJ

    更新日期:2001-03-01 00:00:00

  • Moving through the membrane with filamentous phages.

    abstract::Filamentous phages are small, highly evolved parasites that can reproduce and disseminate without killing their host. During assembly, virion proteins are transferred from the host membrane to the single-stranded DNA phase genome and simultaneously secreted from the cell. Filamentous phage assembly shares certain feat...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(00)88929-5

    authors: Russel M

    更新日期:1995-06-01 00:00:00

  • Viral Carcinogenesis Beyond Malignant Transformation: EBV in the Progression of Human Cancers.

    abstract::Cancer progression begins when malignant cells colonize adjacent sites, and it is characterized by increasing tumor heterogeneity, invasion and dissemination of cancer cells. Clinically, progression is the most relevant stage in the natural history of cancers. A given virus is usually regarded as oncogenic because of ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2016.03.008

    authors: Elgui de Oliveira D,Müller-Coan BG,Pagano JS

    更新日期:2016-08-01 00:00:00

  • Maturation of the [NiFe] hydrogenases.

    abstract::The high degree of similarity that exists between all the [NiFe] hydrogenase operons and the near universality of hydrogen metabolism among microorganisms suggest that the microbial ability to metabolize hydrogen is of great importance and ancient origin. The large number of genes present in these operons, which are m...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(01)02009-1

    authors: Casalot L,Rousset M

    更新日期:2001-05-01 00:00:00

  • Building Walls: Work That Never Ends.

    abstract::Fluorescent amino acid analogs have proven to be useful tools for studying the dynamics of peptidoglycan metabolism. García-Heredia and colleagues showed that their route of incorporation differs depending on the adjunct fluorophore and applied this property to investigate mycobacterial peptidoglycan synthesis and rem...

    journal_title:Trends in microbiology

    pub_type: 评论,杂志文章

    doi:10.1016/j.tim.2018.11.006

    authors: Botella H,Vaubourgeix J

    更新日期:2019-01-01 00:00:00

  • Predictive Modeling of Influenza Shows the Promise of Applied Evolutionary Biology.

    abstract::Seasonal influenza is controlled through vaccination campaigns. Evolution of influenza virus antigens means that vaccines must be updated to match novel strains, and vaccine effectiveness depends on the ability of scientists to predict nearly a year in advance which influenza variants will dominate in upcoming seasons...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2017.09.004

    authors: Morris DH,Gostic KM,Pompei S,Bedford T,Łuksza M,Neher RA,Grenfell BT,Lässig M,McCauley JW

    更新日期:2018-02-01 00:00:00

  • Where and how do anthrax toxins exit endosomes to intoxicate host cells?

    abstract::The role of Bacillus anthracis virulence factors in its pathogenesis has been subjected to intense investigation with the aim of finding novel preventive and therapeutic protocols. Toxins that are endocytosed and act in the cytosol of host cells have a central role in B. anthracis infection. Understanding of anthrax t...

    journal_title:Trends in microbiology

    pub_type: 杂志文章

    doi:10.1016/j.tim.2007.10.003

    authors: Puhar A,Montecucco C

    更新日期:2007-11-01 00:00:00

  • The Role of the Fungal Cell Wall in the Infection of Plants.

    abstract::The polysaccharide-rich wall, which envelopes the fungal cell, is pivotal to the maintenance of cellular integrity and for the protection of the cell from external aggressors - such as environmental fluxes and during host infection. This review considers the commonalities in the composition of the wall across the fung...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2017.05.015

    authors: Geoghegan I,Steinberg G,Gurr S

    更新日期:2017-12-01 00:00:00

  • Global analysis of a bacterial cell cycle: tracking down necessary functions and their regulators.

    abstract::New, post-genomic analyses are increasing the rate at which information about highly complex processes such as bacterial growth and development can be acquired. The recent use of DNA-microarray and proteomic analysis to study the differentiating bacterium Caulobacter crescentus has provided the first global view of th...

    journal_title:Trends in microbiology

    pub_type: 新闻

    doi:10.1016/s0966-842x(01)02135-7

    authors: Brun YV

    更新日期:2001-09-01 00:00:00

  • Fungal Pathogens: Shape-Shifting Invaders.

    abstract::Fungal infections are on the rise due to new medical procedures that have increased the number of immune compromised patients, antibacterial antibiotics that disrupt the microbiome, and increased use of indwelling medical devices that provide sites for biofilm formation. Key to understanding the mechanisms of pathogen...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2020.05.001

    authors: Min K,Neiman AM,Konopka JB

    更新日期:2020-11-01 00:00:00

  • Detecting virulence and drug-resistance mycobacterial phenotypes in vivo.

    abstract::Bacterial phenotypes are predominantly studied in culture because detection of their specific metabolic pathways in the host is challenging. Development of stable-isotope breath tests, allowing in situ phenotype analyses, may endow diagnostics with new modalities based upon direct monitoring of in vivo microbial metab...

    journal_title:Trends in microbiology

    pub_type: 杂志文章

    doi:10.1016/j.tim.2015.02.013

    authors: Timmins GS

    更新日期:2015-06-01 00:00:00

  • Staphylococcus aureus Pathogenesis: The Importance of Reduced Cytotoxicity.

    abstract::Toxin production clearly contributes to the pathogenesis of Staphylococcus aureus, but that does not mean it is always in the best interest of the pathogen. Indeed, the ability to limit toxin production may provide an important mechanism for persistence, dissemination, and development of invasive disease within an ind...

    journal_title:Trends in microbiology

    pub_type: 杂志文章

    doi:10.1016/j.tim.2016.07.003

    authors: Smeltzer MS

    更新日期:2016-09-01 00:00:00

  • How does Cryptococcus get its coat?

    abstract::During the past few decades, increasing attention has focused on pathogenic fungi both as fascinating research subjects and as the agents of serious illness in diverse patient populations. In particular, opportunistic fungi such as Cryptococcus neoformans command notice as the ranks of their immunocompromised victims ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(00)01890-4

    authors: Doering TL

    更新日期:2000-12-01 00:00:00

  • How does Mycobacterium leprae target the peripheral nervous system?

    abstract::Mycobacterium leprae has the capacity to invade the peripheral nervous system and cause neuropathy. The molecular mechanisms responsible have remained unknown until recently. Identification of the endoneurial laminin-2 isoform and its receptor alpha-dystroglycan as neural targets of M. leprae has not only opened up a ...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(99)01647-9

    authors: Rambukkana A

    更新日期:2000-01-01 00:00:00

  • Cable Bacteria Take a New Breath Using Long-Distance Electricity.

    abstract::Recently, a new group of multicellular microorganisms was discovered, called 'cable bacteria', which are capable of generating and mediating electrical currents across centimetre-scale distances. By transporting electrons from cell to cell, cable bacteria can harvest electron donors and electron acceptors that are wid...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2017.10.011

    authors: Meysman FJR

    更新日期:2018-05-01 00:00:00

  • Host-plant invasion by Rhizobium: the role of cell-surface components.

    abstract::Rhizobia are soil bacteria that can become endosymbionts, reducing atmospheric nitrogen within nodules formed on the roots of legume plants. During tissue and cell invasion, bacterial cell-surface components adapt the bacterium to survive as an endophyte without eliciting host-defence responses. The structures of many...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/0966-842x(94)90004-3

    authors: Kannenberg EL,Brewin NJ

    更新日期:1994-08-01 00:00:00

  • Herpesvirus genetics has come of age.

    abstract::The genetic analysis of the large and complex herpesviruses has been a constant challenge to herpesvirologists. Elegant methods have been developed to produce mutants in infected cells that rely on the cellular recombination machinery. Bacterial artificial chromosomes (BACs), single copy F-factor-based plasmid vectors...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0966-842x(02)02394-6

    authors: Wagner M,Ruzsics Z,Koszinowski UH

    更新日期:2002-07-01 00:00:00

  • Contribution of the Mucosal Microbiota to Bovine Respiratory Health.

    abstract::Recognizing the respiratory tract as a dynamic and complex ecosystem has enhanced our understanding of the pathophysiology of bovine respiratory disease (BRD). There is widespread evidence showing that disease-predisposing factors often disrupt the respiratory microbial ecosystem, provoking atypical colonization patte...

    journal_title:Trends in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tim.2019.04.005

    authors: Zeineldin M,Lowe J,Aldridge B

    更新日期:2019-09-01 00:00:00