Thyrotoxicosis and thyroid storm.

Abstract:

:Thyroid storm represents the extreme manifestation of thyrotoxicosis as a true endocrine emergency. Although Grave's disease is the most common underlying disorder in thyroid storm, there is usually a precipitating event or condition that transform the patient into life-threatening thyrotoxicosis. Treatment of thyroid storm involves decreasing new hormone synthesis, inhibiting the release of thyroid hormone, and blocking the peripheral effects of thyroid hormone. This multidrug, therapeutic approach uses thionamides, iodine, beta-adrenergic receptor antagonists, corticosteroids in certain circumstances, and supportive therapy. Certain conditions may warrant the use of alternative therapy with cholestyramine, lithium carbonate, or potassium perchlorate. After the critical illness of thyroid storm subsides, definitive treatment of the underlying thyrotoxicosis can be planned.

authors

Nayak B,Burman K

doi

10.1016/j.ecl.2006.09.008

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

663-86, vii

issue

4

eissn

0889-8529

issn

1558-4410

pii

S0889-8529(06)00071-5

journal_volume

35

pub_type

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