Genes of the antioxidant system of the honey bee: annotation and phylogeny.

Abstract:

:Antioxidant enzymes perform a variety of vital functions including the reduction of life-shortening oxidative damage. We used the honey bee genome sequence to identify the major components of the honey bee antioxidant system. A comparative analysis of honey bee with Drosophila melanogaster and Anopheles gambiae shows that although the basic components of the antioxidant system are conserved, there are important species differences in the number of paralogs. These include the duplication of thioredoxin reductase and the expansion of the thioredoxin family in fly; lack of expansion of the Theta, Delta and Omega GST classes in bee and no expansion of the Sigma class in dipteran species. The differential expansion of antioxidant gene families among honey bees and dipteran species might reflect the marked differences in life history and ecological niches between social and solitary species.

journal_name

Insect Mol Biol

journal_title

Insect molecular biology

authors

Corona M,Robinson GE

doi

10.1111/j.1365-2583.2006.00695.x

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

687-701

issue

5

eissn

0962-1075

issn

1365-2583

pii

IMB695

journal_volume

15

pub_type

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