Kinetic analysis of the antifungal activity of heated scallop-shell powder against Trichophyton and its possible application to the treatment of dermatophytosis.

Abstract:

:The antifungal activity of scallop-shell powder heated at 1000 degrees C for 1 h against Trichophyton was kinetically investigated and the possibility of applying the powder to the treatment of dermatophytosis was examined. The death rate of T. mentagrophytes NBRC5466 in the heated shell powder slurry increased with powder concentration, following first-order reaction kinetics. Elevated slurry temperatures increased both the apparent first-order death rate constant (k) and the dilution coefficient (n) representing the dependence of k on reagent concentration. The activation energy for the death of NBRC5466 was almost equal to that for bacteria, whereas the n value was much smaller than that for bacteria. In addition, the trial using heated shell powder treatment on feet showed the possibility of its application to treat dermatophytosis.

journal_name

Biocontrol Sci

journal_title

Biocontrol science

authors

Sawai J,Shiga H

doi

10.4265/bio.11.125

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

125-8

issue

3

eissn

1342-4815

issn

1884-0205

journal_volume

11

pub_type

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