Abstract：
:Certain typical gait characteristics such as foot-drop and foot supination are well described in Charcot-Marie-Tooth disease. These are directly related to the primary disease and due to the weakness of ankle dorsiflexors and everters characteristic of this hereditary neuropathy. We analysed 16 subjects aged 8-52 years old (11 with type I, 5 with type II Charcot-Marie-Tooth disease) using three-dimensional gait analysis and identified kinematic features previously unreported. These patients showed a combination of tight tendo achillei, foot-drop, failure of plantar flexion and increased foot supination, but also presented with excessive internal rotation of the knee and/or tibia, knee hyperextension in stance, excessive external rotation at the hips and decreased hip adduction in stance (typical of a broad based gait). These proximal features could have been an adaptation to or consequence of the disrupted ankle and foot biomechanics, however a direct relation to the neuropathy is also possible since sub-normal muscle power was observed at the proximal levels in most subjects on both manual testing and kinetic analysis. Gait analysis is a useful tool in defining the characteristic gait of patients with Charcot-Marie-Tooth disease.
journal_name
Gait Posturejournal_title
Gait & postureauthors
Newman CJ,Walsh M,O'Sullivan R,Jenkinson A,Bennett D,Lynch B,O'Brien Tdoi
10.1016/j.gaitpost.2006.08.006subject
Has Abstractpub_date
2007-06-01 00:00:00pages
120-7issue
1eissn
0966-6362issn
1879-2219pii
S0966-6362(06)00164-0journal_volume
26pub_type
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