Acute liver failure: a review.

Abstract:

:Since publication of the first descriptions of acute liver failure (ALF) as a distinct clinical entity in the 1950's, the understanding of the pathophysiologic mechanisms involved and the management options have increased substantially. ALF still represents a major challenge for todays hepatologists, because it can rapidly lead to multiorgan failure and death that may be preventable with appropriate intervention. This article summarizes the basic patho-physiology underlying ALF, compares epidemiologic trends in the United States, the United Kingdom, and the Far East, and reviews prognostic markers and treatment options for ALF.

journal_name

Clin Liver Dis

journal_title

Clinics in liver disease

authors

Khan SA,Shah N,Williams R,Jalan R

doi

10.1016/j.cld.2006.05.010

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

239-58, vii-viii

issue

2

eissn

1089-3261

issn

1557-8224

pii

S1089-3261(06)00012-2

journal_volume

10

pub_type

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