A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain.

abstract：:Slow field potentials (SFP) lasting up to 5 s followed penicillin-induced bursts in CA3 of guinea pig hippocampal slices and accounted for most of the interburst interval. The longest lasting component of the SFP which was maximal in the distal apical dendritic region was usually absent in s. pyramidale. Potassium flu...

journal_title：Brain research

authors： Schneiderman JH

更新日期：1987-02-10 00:00:00

abstract：:Neurons located in the nucleus raphe magnus (NRM), a region important in the control of nociception, appear to be tonically inhibited by noradrenergic (NA) neurons. Anatomical studies have suggested that the A5 catecholamine nucleus may be the primary source of noradrenergic neurons whose terminals are located in the ...

journal_title：Brain research

authors： Sagen J,Proudfit HK

更新日期：1986-04-02 00:00:00

abstract：:Neonatal treatment with gonadal steroids has been reported to alter morphological as well as functional development in various regions of the brain and spinal cord. Among the observed alterations are changes in numbers of neurons and in the organization and numbers of synapses. These regions have been found to be sexu...

journal_title：Brain research

authors： Wright LL,Smolen AJ

更新日期：1983-06-01 00:00:00

abstract：:Emotional events are preferentially retained in episodic memory. This effect is commonly attributed to enhanced consolidation and has been linked specifically to rapid eye movement (REM) sleep physiology. While several studies have demonstrated an enhancing effect of REM sleep on emotional item memory, it has not been...

journal_title：Brain research

authors： Sopp MR,Michael T,Mecklinger A

更新日期：2018-11-01 00:00:00

abstract：:The uptake and efflux of 36Cl in the lateral ventricle choroid plexus of 1-7-week-old rats were measured to determine if Cl transport changed with age and if such transport responded to inhibitors of CSF secretion and ion transport. The steady-state (30 min) Cl uptakes were 148 +/- 9.4 nmol.mg-1 dry weight at 1 week a...

journal_title：Brain research

authors： Preston JE,Dyas M,Johanson CE

更新日期：1993-10-08 00:00:00

abstract：:In the present study, we performed immunohistochemical studies to investigate the changes of Bcl-2 and Bax in the central nervous system of the transgenic mice expressing a human Cu/Zn SOD mutation. In contrast to the controls, a high density of Bcl-2-IR astrocytes were detected all around the gray matter of the spina...

journal_title：Brain research

authors： Shin CM,Chung YH,Kim MJ,Shin DH,Kim YS,Gurney ME,Lee KW,Cha CI

更新日期：2000-12-29 00:00:00

abstract：:Several studies have examined the activity of neurons in hypothalamic tissue slices. The present experiments studied relationships between neuronal activity (firing rate and thermosensitivity) and tissue survival as a function of time and slice thickness. Rat hypothalamic tissue slices were sectioned at different thic...

journal_title：Brain research

authors： Burgoon PW,Burry RW,Boulant JA

更新日期：1997-11-28 00:00:00

abstract：:We studied whether K+, a potent cerebrovasodilator released by active neurons, participates in the increase in cortical cerebral blood flow (CBF) elicited by stimulation of the cerebellar fastigial nucleus (FN). Rats were anesthetized by continuous administration of halothane (1-3%), paralyzed and artificially ventila...

journal_title：Brain research

authors： Iadecola C,Kraig RP

更新日期：1991-11-01 00:00:00

abstract：:In the adult central nervous system (CNS), GABA and glycine (Gly) are predominant inhibitory neurotransmitters, negatively regulating glutamatergic transmission. In the immature CNS, on the other hand, they act as trophic factors, mediating morphogenesis. In the present study, to investigate their involvement in axona...

journal_title：Brain research

authors： Tatetsu M,Kim J,Kina S,Sunakawa H,Takayama C

更新日期：2012-03-29 00:00:00

abstract：:Hypoxia preconditioning states that a sublethal hypoxia period will afford neuroprotection against a second harmful event. In our experiments, we carried out a procedure for the development of hypoxia preconditioning in adult male Wistar rats using hypoxic exposure (9% O(2); 91% N(2)) for 1 h. The protection against p...

journal_title：Brain research

authors： Rauca C,Zerbe R,Jantze H,Krug M

更新日期：2000-06-16 00:00:00

abstract：:Cultured astrocytes contain immunologically specific aromatic L-amino acid decarboxylase (AADC) protein and express the AADC gene. Following incubation with L-Dopa, glial cultures synthesize and metabolize dopamine. The addition of pyridoxal 5-phosphate did not change the rate of dopamine synthesis. The formation of d...

journal_title：Brain research

authors： Juorio AV,Li XM,Walz W,Paterson IA

更新日期：1993-10-29 00:00:00

abstract：:Patches excised from fields CA1 and CA3 of the hippocampus were used to study AMPA receptor responses to repetitive application of brief pulses of agonist. AMPA receptors in field CA1 exhibited a larger degree of paired-pulse depression and a slower recovery rate from desensitization than those from CA3 patches. Respo...

journal_title：Brain research

authors： Arai A,Lynch G

更新日期：1996-04-15 00:00:00

abstract：:We measured the effects of acute or chronic administration of fenfluramine and phentermine, alone or in combination, on brain dopamine and serotonin release into striatal dialysates of freely moving rats. Samples collected every 30 min were assayed in a single run by high-pressure liquid chromatography. Acute or chron...

journal_title：Brain research

authors： Balcioglu A,Wurtman RJ

更新日期：1998-11-30 00:00:00

abstract：:Rat pinealocytes use L-glutamate as a modulator for melatonin synthesis. Upon binding of L-glutamate to the class II metabotropic glutamate receptor, norepinephrine (NE)-dependent formation of cAMP was inhibited, resulting in decreased serotonin-N-acetyltransferase (NAT) activity and melatonin output. Although L-gluta...

journal_title：Brain research

authors： Ishio S,Yamada H,Craft CM,Moriyama Y

更新日期：1999-12-11 00:00:00

abstract：:Retrograde axonal transport method of the fluorescent tracer FluoroGold (FG) was combined with immunocytochemistry to investigate the occurrence of nitric oxide synthase (NOS), somatostatin (SOM), neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP) in both intrinsic and cortically projecting neurons of the ra...

journal_title：Brain research

authors： Kowiański P,Timmermans JP,Moryś J

更新日期：2001-06-29 00:00:00

abstract：:Levodopa (L-DOPA) is widely used for symptomatic management in Parkinson's disease. We recently showed that (-)-epigallocatechin-3-gallate, a tea polyphenol, not only inhibits L-DOPA methylation, but also protects against oxidative hippocampal neurodegeneration. In the present study, we sought to determine several oth...

journal_title：Brain research

authors： Kang KS,Yamabe N,Wen Y,Fukui M,Zhu BT

更新日期：2013-02-25 00:00:00

abstract：:Superior cervical ganglionectomy (SCGx) has drastic effects on numerous hormonal circadian rhythms and particularly on pineal melatonin secretion. We investigated the hormonal consequences of ablation of the superior cervical ganglion on the corticotropic circadian rhythms in the male rat. Plasma were obtained by samp...

journal_title：Brain research

authors： Siaud P,Mekaouche M,Maurel D,Givalois L,Ixart G

更新日期：1994-08-01 00:00:00

abstract：:The postnasal development of the Na-independent [3H]glutamate binding sites, which exhibit some characteristics of postsynaptic glutamate receptors, has been studied in rat hippocampal membranes. The amount of binding sites (expressed in pmol/hippocampus) represents 4% of the adult level at postnatal day (PND) 4, incr...

journal_title：Brain research

authors： Baudry M,Arst D,Oliver M,Lynch G

更新日期：1981-01-01 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine into the substantia nigra in the rat significantly attenuated cortical spreading depression (CSD)-induced eating from the hemisphere ipsilateral but not contralateral to the lesion. The lateralized decrease in elicited feeding was correlated with postlesion body weight loss, ...

journal_title：Brain research

authors： Siegfried B,Hefti F,Lichtensteiger W,Huston JP

更新日期：1979-01-12 00:00:00

abstract：:A monoclonal antibody was made using the spleen cells of a mouse immunized with chick synaptic membranes and designated as mAb 1D12. It immunoprecipitated 25% of the omega-conotoxin binding protein but no dihydropyridine binding protein solubilized from chick brain membranes. By immunoblotting, a polypeptide of 58-kDa...

journal_title：Brain research

authors： Takahashi M,Arimatsu Y,Fujita S,Fujimoto Y,Kondo S,Hama T,Miyamoto E

更新日期：1991-06-14 00:00:00

abstract：:Infection of neonatal mice with ts1, the neuropathogenic mutant of the Moloney murine leukemia virus, results in motor neuronal death in the brainstem and the spinal cord, with gliosis and demyelination, but no inflammatory cell infiltration into the CNS. To evaluate the possible mechanism(s) of ts1-induced neuropatho...

journal_title：Brain research

authors： Choe W,Stoica G,Lynn W,Wong PK

更新日期：1998-01-01 00:00:00

abstract：:Many phosphorylated extracellular signal-regulated kinase (pERK)-immunoreactive (IR) cells are expressed in the trigeminal spinal subnucleus caudalis (Vc), upper cervical spinal cord (C1-C2), nucleus tractus solitarii (NTS) and paratrigeminal nucleus (Pa5) after capsaicin injection into the whisker pad (WP), masseter ...

journal_title：Brain research

authors： Tsujimura T,Shinoda M,Honda K,Hitomi S,Kiyomoto M,Matsuura S,Katagiri A,Tsuji K,Inoue M,Shiga Y,Iwata K

更新日期：2011-10-12 00:00:00

abstract：:The distribution of neural elements immunoreactive to several peptides with a possible messenger role was studied in the lamprey spinal cord by using an indirect immunofluorescence method. Different patterns of immunoreactive (IR) fibers were detected by antisera raised against cholecystokinin, metorphamide, bombesin,...

journal_title：Brain research

authors： Buchanan JT,Brodin L,Hökfelt T,Van Dongen PA,Grillner S

更新日期：1987-04-07 00:00:00

abstract：:To facilitate the study of the CaMKIIα function in vivo, a CaMKIIα-GFP transgenic mouse line was generated. Here, our goal is to provide the first neuroanatomical characterization of GFP expression in the CNS of this line of mouse. Overall, CaMKIIα-GFP expression is strong and highly heterogeneous, with the dentate gy...

journal_title：Brain research

authors： Wang X,Zhang C,Szábo G,Sun QQ

更新日期：2013-06-26 00:00:00

abstract：:The dentato-olivary projection has been ultrastructurally studied in rats that received a wheatgerm agglutinin-horseradish peroxidase (WGA-HRP) injection in the nucleus lateralis. Ultrathin sections containing the inferior olive have been double-labelled with the GABA-immunogold method. About 97% of the WGA-HRP labell...

journal_title：Brain research

authors： Angaut P,Sotelo C

更新日期：1989-02-13 00:00:00

abstract：:Frequency-current curves for CA1 hippocampal pyramidal neurons are shown to have basically the same shape as those for spinal motoneurones, with a region of shallow slope at low frequencies, preceding a sleep linear or upward convex region at higher frequencies. The frequency range is, however, displaced towards lower...

journal_title：Brain research

authors： Gustafsson B,Wigström H

更新日期：1981-11-02 00:00:00

abstract：:In this study the laminar localization of binding sites for the muscarinic radioligand [3H]3-quinuclidinylbenzilate was studied in somatosensory cortex of infant rat. Using light autoradiographic techniques, [3H]QNB was found to be concentrated in layer IV. Atropine-pretreated pups showed evenly dispersed, nonspecific...

journal_title：Brain research

authors： Kristt DA,Kasper EK

更新日期：1983-06-01 00:00:00

abstract：:Brief force perturbations were applied 30-120 ms prior to onset of step-tracking forearm movements by normal humans. The perturbations altered the first agonist burst of the movement-related triphasic EMG pattern. Perturbations opposing the movement resulted in an increase in the magnitude of the late part of the firs...

journal_title：Brain research

authors： Brown SH,Cooke JD

更新日期：1981-09-14 00:00:00

abstract：:Histone proteins from purified nuclei of neonatal and adult mouse retinas were analyzed and compared utilizing SDS-polyacrylamide gel electrophoresis. Identical procedures were applied to examine the histones extracted from the brains of the same animals. In the newborn and mature retina and brain, 8 histone fractions...

journal_title：Brain research

authors： Perkins PS,Young RW

更新日期：1987-06-01 00:00:00

abstract：:Basal limbic structures (insula, amygdala, hippocampus and surrounding areas) were explored for unit responses to vagal volleys in awake, sitting, squirrel monkeys. Triple shocks were applied every 4 sec to the left cervical vagus nerve. As a control for adventitious activation by extravagal somatic afferents, units r...

journal_title：Brain research

authors： Radna RJ,MacLean PD

更新日期：1981-05-25 00:00:00