Abstract:
PURPOSE:To determine the effect of ophthalmic viscosurgical devices (OVDs) and irrigation/aspiration (I/A) settings on free radical development during phacoemulsification. SETTING:Department of Ophthalmology, Nippon Medical School, Tokyo, Japan. METHODS:Free radicals were detected by the electron spin resonance (ESR) spin-trap method. After a spin-trapping agent, 5,5-dimethyl-1-pyrroline N-oxide 1%, was mixed with the irrigating solution, phacoemulsification simulation was performed in an eye model at 100% ultrasound power levels for 10, 20, and 30 seconds. A high I/A setting (35 mL/min with 250 mm Hg vacuum) and a low I/A setting (15 mL/min with 60 mm Hg vacuum) were used in combination with no OVD, sodium hyaluronate 1% (Healon), sodium hyaluronate 2.3% (Healon5), sodium hyaluronate 3%-chondroitin sulfate 4% (Viscoat), or sodium hyaluronate 1% (Opegan). Immediately after phacoemulsification, the solution in the anterior chamber was collected and signals from the spin adduct were measured using an ESR spectrometer. RESULTS:With the low setting, all OVDs significantly suppressed the signals for up to 20 seconds. At 30 seconds, the signals were still significantly smaller in all OVD groups, except Healon, than those in the no-OVD. With the high setting, the effect was not significant in the Healon and Opegan groups at 10 seconds; by 20 seconds and after, only Viscoat showed significant suppression. CONCLUSIONS:Free radical development in phacoemulsification can be altered by OVD properties and I/A settings. To reduce oxidative stress to the corneal endothelium, attention should be paid to the retention of OVDs in the anterior chamber during phacoemulsification.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Takahashi H,Suzuki H,Shiwa T,Sakamoto Adoi
10.1016/j.jcrs.2006.04.026subject
Has Abstractpub_date
2006-09-01 00:00:00pages
1545-8issue
9eissn
0886-3350issn
1873-4502pii
S0886-3350(06)00736-Xjournal_volume
32pub_type
杂志文章abstract::We describe the intraoperative difficulties encountered in cases of ocular Stevens-Johnson syndrome as a result of a poor ocular surface, the presence of symblepharon, and varying degrees of corneal opacity with secondary poor visibility of anterior segment structures. Modifications to the standard phacoemulsification...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2016.09.012
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To measure the change in visual acuity and vision-related quality of life in patients with both age-related cataract and bilateral age-related macular degeneration (AMD) after cataract surgery. SETTING:Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. DESI...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.09.046
更新日期:2015-06-01 00:00:00
abstract::Advances in technique and equipment have led to a significant increase in the popularity of phacoemulsification and have increased its safety and efficiency. We describe a technique, phakonit, in which the lens is emulsified through a 0.9 mm clear corneal temporal incision. A cortical wash with bimanual irrigation/asp...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)00922-1
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To evaluate potential changes in contrast sensitivity and color discrimination in diabetic patients who had cataract surgery and implantation of the blue-light filtering AcrySof Natural (SN60AT) intraocular lens (IOL) compared with an ultraviolet-only filtering (AcrySof SA60AT) IOL. SETTING:Refractive Surgery ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.04.029
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To determine the risk factors, intraoperative and postoperative complications, therapeutic interventions, and visual outcomes for persistent postoperative inflammation in primary resident-performed cataract surgeries. SETTING:Ben Taub General Hospital, Houston, Texas, USA. DESIGN:Retrospective case series. M...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2018.05.006
更新日期:2018-07-01 00:00:00
abstract::We report 2 cases of serous macular detachment with intraretinal fluid accumulation that developed 1 day after uneventful phacoemulsification surgery. Because of a dilution error, both eyes received 2 mg/0.1 mL of intracameral cefuroxime at the end of surgery. On postoperative day 1, the corrected distance visual acui...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2010.07.007
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To estimate the actual and theoretical risks for visual loss associated with use of the implantable contact lens (ICL). SETTING:Multicenter clinical trial data. METHODS:An established model for estimating the risk for visual loss associated with retinal detachment (RD) following clear lens extraction (CLE) wa...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,评审
doi:10.1016/s0886-3350(02)02040-0
更新日期:2003-07-01 00:00:00
abstract::Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14.0 mm Hg) and at 72 hours (average IOP 11.6 mm Hg) (P less than .001). The per...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(88)80034-8
更新日期:1988-11-01 00:00:00
abstract:PURPOSE:To prospectively assess the effect of preoperative variables such as pupil size on glare, halos, and visual function after photoastigmatic refractive keratectomy (PARK). SETTING:Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA. METHODS:Ninety-three eyes had PARK f...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)00871-9
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:To determine the astigmatic effect of a supero-oblique clear corneal phacoemulsification cataract incision. SETTING:A university-based general ophthalmology practice. METHODS:All eyes having supero-oblique phacoemulsification cataract surgery using the right hand of a single surgeon between April 17, 1997, an...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(99)00074-7
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To determine whether there is a difference in intraocular pressure (IOP) control between extracapsular cataract extraction (ECCE) and phacoemulsification performed after successful trabeculectomy. SETTING:Eye Unit, St. Woolos Hospital, Newport, United Kingdom. METHODS:This retrospective study comprised 55 pat...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(99)00321-1
更新日期:2000-01-01 00:00:00
abstract::Subepithelial fibrosis in the area of peripheral suture placement is an often overlooked phenomenon of healing following uneventful penetrating keratoplasty surgery. Three affected cornea transplant patients whose sutures had been removed were studied using videophotokeratoscopy before and after stripping of the subep...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(96)80282-3
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To evaluate the clinical outcomes of implantation of Ferrara intrastromal corneal ring segments (ICRS) in patients with astigmatism after penetrating keratoplasty (PKP). SETTING:Private clinic, Belo Horizonte, Brazil. DESIGN:Retrospective consecutive case series. METHODS:Chart records of post-PKP patients wh...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.12.037
更新日期:2012-06-01 00:00:00
abstract::A method to measure the power of an intraocular lens (IOL) in situ using an extended range keratometer and a depth measuring apparatus is described. With this method, the IOL power was measured in ten patients with an anterior chamber IOL and in ten patients with a posterior chamber IOL and compared with the labeled p...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(88)80066-x
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To study the intensity of trypan blue and fluorescein staining over time in anterior lens capsules and various intraocular lens (IOL) materials. SETTING:Fritz Eye Associates, Geislingen, Germany. METHODS:Excised anterior lens capsules and IOLs were exposed to trypan blue 0.1% and fluorescein 2% solution to as...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01238-5
更新日期:2002-06-01 00:00:00
abstract::This paper describes a surgical training system for teaching and practicing the necessary skills to perform phacoemulsification, endocapsular phacoemulsification, and small incision intraocular lens insertion techniques. The surgical system includes head, bilateral globes, removable corneas, and replaceable synthetic ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(88)80100-7
更新日期:1988-03-01 00:00:00
abstract::After the ultrasonic tip is introduced into the highly myopic eye and inflow is activated, the anterior chamber deepens, the lens-iris diaphragm is displaced posteriorly, the iris becomes concave, and the pupil dilates from the weight of the water column above the eye. We define a known but undescribed syndrome--the l...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80043-0
更新日期:1994-01-01 00:00:00
abstract::The iris-claw intraocular lens (IOL) was recently approved by the U.S. Food and Drug Administration for the correction of refractive disorders. Previous reports are not uniform regarding its potential to induce inflammatory reaction. We report the case of a young healthy patient who experienced persistent and intolera...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2006.02.079
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:To compare the efficacy of low- and high-molecular-weight sodium hyaluronate in protecting corneal endothelial cells during phacoemulsification. SETTING:Miyata Eye Hospital, Miyakonojo, Miyazaki, Japan. METHODS:One hundred forty-nine eyes of 136 cataract patients were randomly assigned to have cataract surger...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(02)01540-7
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To compare the centration and fixation of silicone plate-haptic intraocular lenses (IOLs) with different-sized positioning holes. SETTING:Eye Clinic of the Johannes Gutenberg-University Mainz, Mainz, Germany. METHODS:In a prospective randomized study, 51 Chiroflex C10 and 56 Chiroflex C11 IOLs were implanted ...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(00)00496-x
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of hyperopic laser in situ keratomileusis (LASIK) in treating hyperopia caused by overcorrected myopic LASIK and to evaluate a new technique to place the hyperopic treatment after lifting the initial myopic flap. SETTING:Open-access outpatient excimer laser surgical facility...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(00)00784-7
更新日期:2001-03-01 00:00:00
abstract:PURPOSE:To characterize the mean topographic shape of the limbus of a normal human eye and determine whether it depends on age or refractive power. SETTING:University of Manchester, Manchester, United Kingdom. DESIGN:Prospective case series. METHODS:Participants with no previous ocular surgeries were included in thi...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2017.02.027
更新日期:2017-05-01 00:00:00
abstract::The first 45 cases of extracapsular cataract extraction, with posterior chamber intraocular lens implantation performed by ophthalmology residents at an urban county hospital were evaluated. These cases, which were performed from March 1983 to June 1984, involved a patient population that was primarily black and Hispa...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(86)80054-2
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To evaluate the Nidek handheld automated keratometer and compare it with the manual Zeiss keratometer. SETTING:St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom. METHODS:Forty-five normal adult volunteers were included in the study. Three sets of randomized keratometry measur...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(98)80333-7
更新日期:1998-03-01 00:00:00
abstract:UNLABELLED:A 77-year-old woman with primary open-angle glaucoma was referred for surgical evaluation after failing to achieve target intraocular pressure (IOP) despite previous combined phacotrabeculectomy and Ahmed valve implantations. The IOP prior to surgery was 28 mm Hg on topical dorzolamide-timolol, latanoprost, ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.06.017
更新日期:2014-08-01 00:00:00
abstract::We describe 2 women with high myopia of -12.0 and -18.0 diopters who presented with myopic macular hemorrhages 1 and 4 days, respectively, after being treated by laser in situ keratomileusis (LASIK). One hemorrhage was related to a pre-existing choroidal neovascularization and the other to the presence of lacquer crac...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(00)00313-8
更新日期:2000-06-01 00:00:00
abstract:PURPOSE:To evaluate the results of photorefractive keratectomy (PRK) to treat undercorrected radial keratotomy (RK). SETTING:Instituto de Oftalmologia Tadeu Cvintal, São Paulo, Brazil. METHODS:A consecutive series of 28 eyes that had PRK to treat residual myopia after RK were studied. Refractive visual and safety dat...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(96)80189-1
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To compare visual outcomes in patients with cataract surgery and bilateral implantation of a trifocal or bifocal intraocular lens (IOL). SETTING:University Eye Clinic Maastricht, the Netherlands. DESIGN:Prospective randomized clinical trial. METHODS:Eyes with cataract and less than 1.0 diopter (D) of corneal...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrs.2015.08.011
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To examine changes in visual, psychological, and functional disability in older people waiting for cataract extraction and 6 months after surgery. SETTING:Community-based study in Northeast England. METHODS:Participants were 92 patients (mean age 78.1 years +/- 6.5 [SD], 79% female) with age-related cataract....
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.07.040
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To determine the in vitro bacterial adherence to intraocular lenses (IOLs) routinely used at 1 center. SETTING:University Hospital of Vienna, Vienna, Austria. METHODS:Four types of rigid IOLs (hydrophobic poly[methyl methacrylate] [PMMA] and hydrophilic heparin-surface-modified PMMA) and 5 types of foldable i...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01741-8
更新日期:2003-02-01 00:00:00