Lipid domains in bacterial membranes.

abstract：:A collection of 20 strains of Helicobacter pylori from several regions of the world was studied to better understand the population genetic structure and diversity of this species. Sequences of fragments from seven housekeeping genes (atpA, efp, mutY, ppa, trpC, ureI, yphC ) and two virulence-associated genes (cagA, v...

journal_title：Molecular microbiology

authors： Achtman M,Azuma T,Berg DE,Ito Y,Morelli G,Pan ZJ,Suerbaum S,Thompson SA,van der Ende A,van Doorn LJ

更新日期：1999-05-01 00:00:00

abstract：:The sensor kinase/response regulator system KdpD/KdpE of Escherichia coli regulates the expression of the kdpFABC operon, which encodes the high affinity K+ transport system KdpFABC. The membrane-bound sensor kinase KdpD consists of four transmembrane domains, a large cytoplasmic N-terminal domain and a cytoplasmic C-...

journal_title：Molecular microbiology

authors： Heermann R,Fohrmann A,Altendorf K,Jung K

更新日期：2003-02-01 00:00:00

abstract：:Strains of Escherichia coli have been produced which express very high levels of the tRNA(1Leu) isoacceptor. This was accomplished by transforming cells with plasmids containing the leuV operon which encodes three copies of the tRNA(1Leu) gene. Most transformants grew very slowly and exhibited a 15-fold increase in ce...

journal_title：Molecular microbiology

authors： Wahab SZ,Rowley KO,Holmes WM

更新日期：1993-01-01 00:00:00

abstract：:Arginine auxotrophs of the dinitrogen-fixing cyanobacterium Anabaena species strain PCC 7120 were isolated after ultraviolet light mutagenesis and penicillin enrichment. Two of these auxotrophs were complemented by a cosmid gene library of the wild-type strain established in Escherichia coli that was transferred en ma...

journal_title：Molecular microbiology

authors： Floriano B,Herrero A,Flores E

更新日期：1992-08-01 00:00:00

abstract：:The suf and isc operons of Escherichia coli have been implicated in Fe-S cluster assembly. However, it has been unclear why E. coli has two systems for Fe-S cluster biosynthesis. We have examined the regulatory characteristics and mutant phenotypes of both operons to discern if the two operons have redundant functions...

journal_title：Molecular microbiology

authors： Outten FW,Djaman O,Storz G

更新日期：2004-05-01 00:00:00

abstract：:A model for the topology of the PhoE porin has been proposed according to which the polypeptide traverses the outer membrane sixteen times mostly as amphipathic beta-sheets, thereby exposing eight loops at the cell surface. Until now, no evidence has been obtained for the surface exposure of the third loop. Recently, ...

journal_title：Molecular microbiology

authors： Struyvé M,Visser J,Adriaanse H,Benz R,Tommassen J

更新日期：1993-01-01 00:00:00

abstract：:Human gut bifidobacteria rely on ATP-binding cassette (ABC) transporters for oligosaccharide uptake. Multiple oligosaccharide-specific solute-binding protein (SBP) genes are occasionally associated with a single ABC transporter, but the significance of this multiplicity remains unclear. Here, we characterize BlMnBP1 a...

journal_title：Molecular microbiology

authors： Ejby M,Guskov A,Pichler MJ,Zanten GC,Schoof E,Saburi W,Slotboom DJ,Abou Hachem M

更新日期：2019-07-01 00:00:00

abstract：:GS-1 (ncu04189) is a protein required for the synthesis of beta-1,3-glucan in Neurospora crassa. As chitin, beta-1,3-glucan is a morphogenetically relevant component of the fungal cell wall. Previously, we showed that chitin synthases are delivered to the growing hyphal tip of N. crassa by secretory microvesicles that...

journal_title：Molecular microbiology

authors： Verdín J,Bartnicki-Garcia S,Riquelme M

更新日期：2009-12-01 00:00:00

abstract：:Histidine kinases function as dimers. The kinase domain of the osmosensing histidine kinase EnvZ of Escherichia coli consists of two domains: domain A (67 residues) responsible for histidine phosphotransfer and dimerization, and domain B (161 residues) responsible for the catalytic and ATP-binding function. The indivi...

journal_title：Molecular microbiology

authors： Qin L,Dutta R,Kurokawa H,Ikura M,Inouye M

更新日期：2000-04-01 00:00:00

abstract：:Dimerization and inactivation of ribosomes in Escherichia coli is a two-step process that involves the binding of ribosome modulation factor (RMF) and hibernation promotion factor (HPF). Lactococcus lactis MG1363 expresses a protein, YfiA(L) (l) , which associates with ribosomes in the stationary phase of growth and i...

journal_title：Molecular microbiology

authors： Puri P,Eckhardt TH,Franken LE,Fusetti F,Stuart MC,Boekema EJ,Kuipers OP,Kok J,Poolman B

更新日期：2014-01-01 00:00:00

abstract：:A two-hybrid approach was applied to screen for proteins with the ability to interact with PHB synthase (PhaC1) of Ralstonia eutropha. The H16_A0141 gene (phaM) was identified in the majority of positive clones. PhaM (26.6 kDa) strongly interacted with PhaC1 and with phasin PhaP5 but not with PhaP1 or other PHB granul...

journal_title：Molecular microbiology

authors： Pfeiffer D,Wahl A,Jendrossek D

更新日期：2011-11-01 00:00:00

abstract：:The cheA gene encodes two overlapping polypeptides with a common carboxyl terminus: CheAL and CheAS. CheAL plays a central role in the Escherichia coli chemotaxis signalling pathway by autophosphorylation and transferring the phosphate to both CheY and CheB. On the other hand, the physiological functions of CheAS rema...

journal_title：Molecular microbiology

authors： Wang H,Matsumura P

更新日期：1996-02-01 00:00:00

abstract：:In vivo and in vitro analyses indicate that transcription of the argO gene coding for an arginine exporter is regulated by the global transcriptional regulator Lrp, an effect that went by unnoticed in previous genome-scale screenings of the Lrp regulatory network in Escherichia coli. Lrp activates the argO promoter fo...

journal_title：Molecular microbiology

authors： Peeters E,Nguyen Le Minh P,Foulquié-Moreno M,Charlier D

更新日期：2009-12-01 00:00:00

abstract：:The nucleotide sequence of a 2711bp DNA segment which contains the N-terminal coding sequence and the 5' flanking region of a crystal protein gene (bta) from Bacillus thuringiensis subsp. aizawai 7.29 has been determined. The coding region encodes an 824 amino-acid polypeptide corresponding to a carboxy-terminally tru...

journal_title：Molecular microbiology

authors： Sanchis V,Lereclus D,Menou G,Chaufaux J,Guo S,Lecadet MM

更新日期：1989-02-01 00:00:00

abstract：:Salmonella typhimurium responds to a variety of environmental stresses by accumulating the alternative sigma factor sigmaS. The repertoire of sigmaS -dependent genes that are subsequently expressed confers tolerance to a variety of potentially lethal conditions including low pH and stationary phase. The mechanism(s) r...

journal_title：Molecular microbiology

authors： Webb C,Moreno M,Wilmes-Riesenberg M,Curtiss R 3rd,Foster JW

更新日期：1999-10-01 00:00:00

abstract：:In the yeast Saccharomyces cerevisiae, the regulation of cell types by homeodomain transcription factors is a key paradigm; however, many questions remain regarding this class of developmental regulators in other fungi. In the human fungal pathogen Cryptococcus neoformans, the homeodomain transcription factors Sxi1α a...

journal_title：Molecular microbiology

authors： Mead ME,Stanton BC,Kruzel EK,Hull CM

更新日期：2015-03-01 00:00:00

abstract：:Alternative oxidase (AOX) is a respiratory oxidase found in certain eukaryotes and bacteria; however, its role in bacterial physiology is unclear. Exploiting the genetic tractability of the bacterium Vibrio fischeri, we explore the regulation of aox expression and AOX function. Using quantitative PCR and reporter assa...

journal_title：Molecular microbiology

authors： Dunn AK,Karr EA,Wang Y,Batton AR,Ruby EG,Stabb EV

更新日期：2010-07-01 00:00:00

abstract：:Mycelial fungi play a central role in element cycling in nature by degrading dead organic material such as wood. Fungal colonization of a substrate starts with the invasion of exploring hyphae. These hyphae secrete enzymes that convert the organic material into small molecules that can be taken up by the fungus to ser...

journal_title：Molecular microbiology

authors： Vinck A,Terlou M,Pestman WR,Martens EP,Ram AF,van den Hondel CA,Wösten HA

更新日期：2005-11-01 00:00:00

abstract：:The gene encoding the multifunctional enzyme enniatin synthetase from Fusarium scirpi (esyn1) was isolated and characterized by transcriptional mapping and expression studies in Escherichia coli. This is the first example of a gene encoding an N-methyl peptide synthetase. The nucleotide sequence revealed an open readi...

journal_title：Molecular microbiology

authors： Haese A,Schubert M,Herrmann M,Zocher R

更新日期：1993-03-01 00:00:00

abstract：:In cyanobacteria and chloroplasts, exposure to HL damages the photosynthetic apparatus, especially the D1 subunit of Photosystem II. To avoid chronic photoinhibition, a PSII repair cycle operates to replace damaged PSII subunits with newly synthesised versions. To determine the sub-cellular location of this process, w...

journal_title：Molecular microbiology

authors： Sacharz J,Bryan SJ,Yu J,Burroughs NJ,Spence EM,Nixon PJ,Mullineaux CW

更新日期：2015-05-01 00:00:00

abstract：:The fluidity and phase state of bacterial lipid bilayers commonly change in response to ambient environmental conditions to maintain the critical functions of the envelope as a semipermeable and selective boundary. A special, and intricate, set of alterations in membrane lipid metabolism is elicited by conditions caus...

journal_title：Molecular microbiology

authors： DiRusso CC,Nyström T

更新日期：1998-01-01 00:00:00

abstract：:In prokaryotes, the principal signal transduction systems operating at the level of protein phosphorylation are the two-component systems. A number of hybrid histidine protein kinases in these systems contain several receiver domains, however, the function of these receiver domains is unknown. The RodK kinase in Myxoc...

journal_title：Molecular microbiology

authors： Rasmussen AA,Wegener-Feldbrügge S,Porter SL,Armitage JP,Søgaard-Andersen L

更新日期：2006-04-01 00:00:00

abstract：:The creA gene of A. nidulans encodes a wide-domain regulatory protein mediating carbon catabolite repression. Northern blot analysis of creA mRNA revealed a complex expression profile: the addition of monosaccharides to a carbon-starved culture of A. nidulans provoked a strong transient stimulation of creA transcript ...

journal_title：Molecular microbiology

authors： Strauss J,Horvath HK,Abdallah BM,Kindermann J,Mach RL,Kubicek CP

更新日期：1999-04-01 00:00:00

abstract：:Crs5 is a Saccharomyces cerevisiae Metallothionein (MT), non-homologous to the paradigmatic Cu-thionein Cup1. Although considered a secondary copper-resistance agent, we show here that it determines survival under zinc overload in a CUP1-null background. Its overexpression prevents the deleterious effects exhibited by...

journal_title：Molecular microbiology

authors： Pagani A,Villarreal L,Capdevila M,Atrian S

更新日期：2007-01-01 00:00:00

abstract：:During Bacillus subtilis endospore formation, a complex protein coat is assembled around the maturing spore. The coat is made up of more than two dozen proteins that form an outer layer, which provides chemical resistance, and an inner layer, which may play a role in the activation of germination. A third, amorphous l...

journal_title：Molecular microbiology

authors： Seyler RW Jr,Henriques AO,Ozin AJ,Moran CP Jr

更新日期：1997-09-01 00:00:00

abstract：:In general, wild Escherichia coli strains can grow effectively under moderately acidic organic acid-rich conditions. We found that the Shiga Toxin-producing E. coli (STEC) O157:H7 NGY9 grows more quickly than a K-12 strain in Luria-Bertani (LB)-2-morpholinoethanesulphonic acid (MES) broth supplemented with acetic acid...

journal_title：Molecular microbiology

authors： Barua S,Yamashino T,Hasegawa T,Yokoyama K,Torii K,Ohta M

更新日期：2002-02-01 00:00:00

abstract：:We have identified and characterized three genes, SUT1, SUT2 and SUT3, that encode glucose transporters of the yeast Pichia stipitis. When expressed in a Saccharomyces cerevisiae hxt null mutant strain that is unable to take up monosaccharides, all three proteins restored growth on glucose. Sequencing of the genes rev...

journal_title：Molecular microbiology

authors： Weierstall T,Hollenberg CP,Boles E

更新日期：1999-02-01 00:00:00

abstract：:The cytokinetic apparatus of bacteria is initially formed by the polymerization of the tubulin-like FtsZ protein into a ring structure at midcell. This so-called Z-ring facilitates the recruitment of many additional proteins to the division site to form the mature divisome machine. Although the assembly pathway leadin...

journal_title：Molecular microbiology

authors： Tsang MJ,Bernhardt TG

更新日期：2015-03-01 00:00:00

abstract：:A reputed iron-responsive region, which contains multiple nuclear protein-binding DNA sequences, was shown previously to regulate iron-inducible transcription of the ap65-1 gene in the protozoan pathogen, Trichomonas vaginalis. These DNA sequences include two overlapping MYB recognition elements (MRE-1/MRE-2r) and thr...

journal_title：Molecular microbiology

authors： Ong SJ,Huang SC,Liu HW,Tai JH

更新日期：2004-06-01 00:00:00

abstract：:Salmonella translocate a group of type III effectors into the host cells to induce entry, promote survival and cause intestinal inflammation. Although the biochemical and cellular mechanisms of how bacterial effectors function inside host cells remain largely unknown, studies have indicated that a likely strategy is t...

journal_title：Molecular microbiology

authors： Zhang Y,Higashide WM,McCormick BA,Chen J,Zhou D

更新日期：2006-11-01 00:00:00