Can pancreatitis be associated with amiodarone hepatotoxicity?

Abstract:

:We report a patient with classical features of amiodarone hepatotoxicity who died of progressive liver failure. Throughout the course of his illness, he had epigastric pain, nausea, vomiting, and persistent mild to moderate elevation of amylase and lipase in his serum and peritoneal fluid. Pancreatitis due to amiodarone has not been reported. We raise the question of whether or not the pancreas is yet another organ subject to amiodarone toxicity and speculate as to possible pathogenesis. We suggest that patients on amiodarone who develop abnormal liver enzymes, nausea, vomiting, or abdominal pain be evaluated not only for hepatotoxicity, but for pancreatitis as well.

journal_name

J Clin Gastroenterol

authors

Sastri SV,Diaz-Arias AA,Marshall JB

doi

10.1097/00004836-199002000-00018

subject

Has Abstract

pub_date

1990-02-01 00:00:00

pages

70-3

issue

1

eissn

0192-0790

issn

1539-2031

journal_volume

12

pub_type

杂志文章
  • The Role of Insulin-like Growth Factor (IGF) Axis in Early Diagnosis of Pancreatic Adenocarcinoma (PDAC).

    abstract::New-onset diabetes mellitus (DM) is one of the first symptoms of pancreatic adenocarcinoma (PDAC). The frequency of endocrine disorders is estimated between 40% and 80% in patients with pancreatic cancer. DM is a risk factor for cancer development but it may also be a consequence of the tumor growth. Data confirming t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0000000000001073

    authors: Wlodarczyk B,Gasiorowska A,Malecka-Panas E

    更新日期:2018-08-01 00:00:00

  • Change in serum hepatitis B surface antigen level and its clinical significance in treatment-naïve, hepatitis B e antigen-positive patients receiving entecavir.

    abstract:BACKGROUND/AIM:We investigated changes in hepatitis B surface antigen (HBsAg) level and its correlation with clinical outcomes in treatment-naive chronic hepatitis B (CHB) patients undergoing entecavir therapy. PATIENTS AND METHODS:Among 51 hepatitis B e antigen (HBeAg)-positive treatment-naive CHB patients receiving ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1097/MCG.0b013e3181d52946

    authors: Jung YK,Kim JH,Lee YS,Lee HJ,Yoon E,Jung ES,Hong SK,Joo MK,Yeon JE,Park JJ,Kim JS,Bak YT,Byun KS

    更新日期:2010-10-01 00:00:00

  • Trends in outpatient resource utilizations and outcomes for Medicare beneficiaries with nonalcoholic fatty liver disease.

    abstract:BACKGROUND AND AIM:Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease. The objective of this study was to describe the recent trend of health care resource utilization and short-term mortality of Medicare beneficiaries with NAFLD. METHODS:This study utilized data from a ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000071

    authors: Younossi ZM,Zheng L,Stepanova M,Henry L,Venkatesan C,Mishra A

    更新日期:2015-03-01 00:00:00

  • Cetirizine-induce cholestasis.

    abstract::Cetirizine, a human metabolite of hydroxyzine, is a selective H1-receptor antagonist currently approved for the treatment of seasonal allergic rhinitis, perennial allergic rhinitis, and chronic urticaria. In U.S. clinical trials, transient reversible hepatic transaminase elevations were observed in <2% of patients dur...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200010000-00016

    authors: Fong DG,Angulo P,Burgart LJ,Lindor KD

    更新日期:2000-10-01 00:00:00

  • Leiomyosarcoma of the duodenum recognized preoperatively.

    abstract::We report the preoperative histologic diagnosis of leiomyosarcoma of the duodenum and review the clinical aspects and treatment of this tumor. The endoscopic techniques were critical in obtaining the diagnosis and deciding the treatment plan. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198310000-00013

    authors: Holst L,Burstein S,Morankar V,Goldberg M

    更新日期:1983-10-01 00:00:00

  • Hereditary pancreatitis in a Chinese family.

    abstract::In a Chinese family with hereditary pancreatitis, two members are proven to have chronic pancreatitis. The propositus, a 31-year-old man, had epigastric pain since the age of 18. Multiple calcifications in the region of the pancreas were seen on plain film of the abdomen, ultrasonography, computed tomography, and endo...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199002000-00021

    authors: Lin JT,Wang TH,Chen DS

    更新日期:1990-02-01 00:00:00

  • Prolonged cholestasis after cyproheptadine-induced acute hepatitis.

    abstract::We report a patient in whom cyproheptadine-induced hepatitis was followed by prolonged cholestasis marked by elevation of serum alkaline phosphatase levels, gammaglutamyltransferase and bile acid levels, and disappearance of small bile ducts. Chlorpromazine and imipramine, which can induce a similar acute hepatitis fo...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198702000-00026

    authors: Larrey D,Geneve J,Pessayre D,Machayekhi JP,Degott C,Benhamou JP

    更新日期:1987-02-01 00:00:00

  • Development of Image-enhanced Endoscopy of the Gastrointestinal Tract: A Review of History and Current Evidences.

    abstract::Endoscopy imaging of the gastrointestinal (GI) tract has evolved tremendously over the last few decades. Key milestones in the development of endoscopy imaging include the use of various dyes for chromoendoscopy, the application of optical magnification in endoscopy, the introduction of high-definition image capturing...

    journal_title:Journal of clinical gastroenterology

    pub_type: 历史文章,杂志文章

    doi:10.1097/MCG.0000000000000960

    authors: Ho SH,Uedo N,Aso A,Shimizu S,Saito Y,Yao K,Goh KL

    更新日期:2018-04-01 00:00:00

  • Multiple esophageal webs: treatment and follow-up of seven patients.

    abstract::We have treated seven patients with multiple esophageal webs without a predisposing disorder. The patients ranged in age from 34 to 61 years and had suffered from dysphagia for 4 to 26 years. None had skin disease, a history of ingestion of a potentially caustic substance, or evidence of gastroesophageal reflux diseas...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199706000-00003

    authors: Longstreth GF,Sitzer ME

    更新日期:1997-06-01 00:00:00

  • Vertical banded gastroplasty for the treatment of morbid obesity.

    abstract::We report the technique and results of vertical banded gastroplasty in 86 morbidly obese patients. At 12 months, the patients had lost a mean of 57% of their excess body weight; 36 months, they had lost 70%. The most severe early complication was perforation of the esophagus. Other complications included disruption of...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198812000-00017

    authors: Bogokowsky H,Slutzki S,Waron M,Abramsohn R,Halpern Z,Negri M,Zaidenstein L

    更新日期:1988-12-01 00:00:00

  • Gunshot cholecystitis.

    abstract::A 15-year-old boy developed traumatic cholecystitis from a BB shot that lodged in his gallbladder. This is an unusual cause of gallbladder disease, and we review the literature. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-199512000-00016

    authors: Petersen JM,Knight TT

    更新日期:1995-12-01 00:00:00

  • Motility of the transverse colon used for esophageal replacement.

    abstract::The authors studied the motility of transverse colon used for reconstruction of the pharyngogastric transit after esophagectomy. The study included 10 patients who underwent esophagectomy 15 to 201 months (median, 48.5 months) before motility evaluation. Nine patients underwent operation because of caustic injury and ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200203000-00005

    authors: Dantas RO,Mamede RC

    更新日期:2002-03-01 00:00:00

  • Esophageal tuberculosis presenting as intramural esophagogastric hematoma in a hemophiliac patient.

    abstract::A spontaneous intramural esophagogastric hematoma developed in a patient with hemophilia A. The hematoma did not resolve after antihemophiliac factor replacement but ruptured into the stomach causing massive gastrointestinal bleeding. The associated enlarged right tracheobronchial gland and the histopathological findi...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199203000-00017

    authors: Intragumtornchai T,Israsena S,Benjacholamard V,Lerdlum S,Benjavongkulchai S

    更新日期:1992-03-01 00:00:00

  • Quality of Sleep and Coexistent Psychopathology Have Significant Impact on Fatigue Burden in Patients With Inflammatory Bowel Disease.

    abstract:BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000729

    authors: Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

    更新日期:2018-05-01 00:00:00

  • Usefulness of serum N-terminal-ProBNP in distinguishing ascites due to cirrhosis from ascites due to heart failure.

    abstract:BACKGROUND:Ascites due to cirrhosis may be difficult to distinguish from ascites due to heart failure by clinical features alone. More invasive testing is usually necessary, such as measurement of the hepatic venous pressure gradient, or paracentesis with measurement of the ascitic fluid total protein. AIM:The aim of ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e318198113b

    authors: Sheer TA,Joo E,Runyon BA

    更新日期:2010-01-01 00:00:00

  • Body position affects recumbent postprandial reflux.

    abstract::There is a lack of consensus as to whether there is a difference in the amount of gastroesophageal reflux when lying with the right versus the left side down. In an attempt to answer this question we conducted a two-part study. The first consisted of a questionnaire distributed to 103 gastroenterologists with a specia...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-199406000-00004

    authors: Katz LC,Just R,Castell DO

    更新日期:1994-06-01 00:00:00

  • Acute pancreatitis in childhood: analysis of literature data.

    abstract:GOALS:To review the published experience with acute pancreatitis in childhood. STUDY:Computerized search of the English medical literature since 1965 using MEDLINE. RESULTS:Details of 589 patients were reviewed. Mean age was 9.2 +/- 2.4 years (range: 1 week to 21 years). Male to female ratio was 1.2. Etiologies inclu...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/00004836-200308000-00015

    authors: Benifla M,Weizman Z

    更新日期:2003-08-01 00:00:00

  • Primary biliary cirrhosis and Graves' disease.

    abstract::We describe a patient with primary biliary cirrhosis associated with Graves' disease and discuss the possible autoimmune connections between the two disorders. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198510000-00014

    authors: Nieri S,Riccardo GG,Salvadori G,Surrenti C

    更新日期:1985-10-01 00:00:00

  • Sociodemographic characteristics, life stressors, and peptic ulcer. A prospective study.

    abstract::The role of psychosocial factors in peptic ulcer remains controversial. We have investigated the relationship between socioeconomic status, concrete stressors, and ulcers in a longitudinally followed, population-based cohort, taking confounding risk factors into account. A total of 6,928 adults completed the Alameda C...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199510000-00004

    authors: Levenstein S,Kaplan GA,Smith M

    更新日期:1995-10-01 00:00:00

  • Crohn's disease associated with autoimmune neutropenia.

    abstract::We report a 29-year-old woman with a 20-year history of Crohn's disease and neutropenia. Because of repeated complications of Crohn's disease, she has undergone three intestinal resections and also has had recurrent skin abscesses, sinusitis, and pneumonia. Persistent neutropenia has been noted throughout the course o...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199106000-00016

    authors: Stevens C,Peppercorn MA,Grand RJ

    更新日期:1991-06-01 00:00:00

  • Objective detection of esophagopharyngeal reflux in patients with hoarseness and endoscopic signs of laryngeal inflammation.

    abstract:GOALS:We aimed to quantify pharyngeal exposure to gastric contents in patients diagnosed with reflux-related hoarseness and healthy controls using new diagnostic techniques. BACKGROUND:Hoarseness with typical signs on laryngoscopy is commonly thought to be caused by esophagopharyngeal reflux. New methods are proposed ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000011

    authors: Hayat JO,Yazaki E,Moore AT,Hicklin L,Dettmar P,Kang JY,Sifrim D

    更新日期:2014-04-01 00:00:00

  • Postpartum Laboratory Follow-up in Women With Hepatitis B in Massachusetts From 2007 to 2012.

    abstract:GOALS:To determine postpartum hepatitis B virus (HBV) laboratory testing rates and identify factors associated with a lack of follow-up testing in Massachusetts. BACKGROUND:Screening for HBV infection in pregnant women is standard of care. Guidelines recommend that patients with chronic HBV have ongoing care and labor...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000530

    authors: Chang MS,Barton K,Crockett M,Tuomala RE,Rutherford AE,Mutinga ML,Andersson KL,Brown RS Jr,Oken E,Ukomadu C

    更新日期:2016-07-01 00:00:00

  • Epidemiology of Crohn's Disease.

    abstract::Although our current understanding is limited, epidemiologic investigation of Crohn's disease holds great promise. Certain aspects of the epidemiology are clear. The incidence of Crohn's disease, which has increased over the past few decades, may have reached a plateau. The disease has its peak onset in early life, wi...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198604000-00011

    authors: Sandler RS,Golden AL

    更新日期:1986-04-01 00:00:00

  • AccuStat whole blood fingerstick test for Helicobacter pylori infection: a reliable screening method.

    abstract::Helicobacter pylori antibody testing is accurate for diagnosing untreated patients. Rapid serum testing is as accurate as formal enzyme-linked immunosorbent assay (ELISA) testing. As whole blood fingerstick tests may become the diagnostic method of choice if they are of similar accuracy, 51 patients were studied who h...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199807000-00010

    authors: Harrison JR,Bevan J,Furth EE,Metz DC

    更新日期:1998-07-01 00:00:00

  • Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole.

    abstract::Acid-reducing drugs can cause increased growth of microbes, including fungus, because of high gastric pH. Our purpose was to evaluate the occurrence of mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and to compare the effects of cimetidine, famotidine, and omeprazole. Eighty patients with duod...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-199607000-00003

    authors: Goenka MK,Kochhar R,Chakrabarti A,Kumar A,Gupta O,Talwar P,Mehta SK

    更新日期:1996-07-01 00:00:00

  • Progression to cirrhosis in Latinos with chronic hepatitis C: differences in Puerto Ricans with and without human immunodeficiency virus coinfection and along gender.

    abstract:BACKGROUND:Hepatitis C virus (HCV) infection is prevalent in Latinos. There is some evidence that progression to cirrhosis is more rapid. END POINTS:To calculate time of cirrhosis from time of HCV infection in a large Latino population. Other end points were to assess variables that predict cirrhosis and the effect of...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/01.mcg.0000210105.66994.dc

    authors: Rodríguez-Torres M,Ríos-Bedoya CF,Rodríguez-Orengo J,Fernández-Carbia A,Marxuach-Cuétara AM,López-Torres A,Salgado-Mercado R,Bräu N

    更新日期:2006-04-01 00:00:00

  • Are Anti-Tumor Necrosis Factor Trough Levels Predictive of Mucosal Healing in Patients With Inflammatory Bowel Disease?: A Systematic Review and Meta-Analysis.

    abstract:GOALS:Our primary goal was to evaluate whether anti-tumor necrosis factor (TNF)-α trough levels above author-determined thresholds are associated with increased rates of mucosal healing among patients with Crohn's disease and ulcerative colitis. BACKGROUND:The introduction of anti-TNF agents has considerably advanced ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MCG.0000000000000441

    authors: Barnes EL,Allegretti JR

    更新日期:2016-10-01 00:00:00

  • Gastric ulcer healing and basic fibroblast growth factor: effects of lansoprazole and famotidine.

    abstract::We examined the effects of lansoprazole and famotidine on gastric basic fibroblast growth factor (bFGF) levels and ulcer healing in patients with gastric ulcer. Sixteen patients with active gastric ulcer were divided into two groups and received treatment with lansoprazole 30 mg/day or famotidine 40 mg/day. They were ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-199506002-00002

    authors: Tsuji S,Kawano S,Higashi T,Mukuda T,Imaizumi T,Tatsumi T,Miura N,Miyajima K,Fukuda M,Noguchi M

    更新日期:1995-01-01 00:00:00

  • Cholangitis glandularis proliferans. A histologic variant of primary sclerosing cholangitis with distinctive clinical and pathological features.

    abstract::This is the first report in the American literature of a recently described histologic variant of primary sclerosing cholangitis (PSC). Only six examples of this unique entity, called cholangitis glandularis proliferans (CGP), or proliferative cholangitis, have previously been reported. This disorder typically present...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Graham SM,Barwick K,Cahow CE,Baker CC

    更新日期:1988-10-01 00:00:00

  • Life-threatening enterocolitis after gold salt therapy.

    abstract::Two patients developed life-threatening enterocolitis after receiving gold salt therapy. This disorder is attended by a mortality rate of 50% but the intestinal lesion appears to be reversible. The mechanism of the drug toxicity is not known. The course may be fulminant and recovery may occur only after many weeks. To...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-197906000-00006

    authors: Sckolnick BR,Katz LA,Kozower M

    更新日期:1979-06-01 00:00:00