Depression and associated physical diseases and symptoms.

abstract：:As one of the most common neurological disorders, epilepsy has devastating behavioral, social, and occupational consequences and is associated with accumulating brain damage and neurological deficits. Epilepsy comprises a large number of syndromes, which vary greatly with respect to their etiology and clinical feature...

journal_title：Dialogues in clinical neuroscience

authors： Beck H,Elger CE

更新日期：2008-01-01 00:00:00

abstract：:There is mounting evidence that recurrent mood disorders - once considered "good prognosis diseases"- are, in fact, often very severe and life-threatening illnesses. Furthermore, although mood disorders have traditionally been conceptualized as neurochemical disorders, there is now evidence from a variety of sources d...

journal_title：Dialogues in clinical neuroscience

authors： Quiroz JA,Manji HK

更新日期：2002-03-01 00:00:00

abstract：:The traditional categorical classification system and new diagnostic systems will be discussed in this issue.
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journal_title：Dialogues in clinical neuroscience

authors： Thibaut F

更新日期：2020-03-01 00:00:00

abstract：:Treatment of Parkinson's disease (PD) is complex and often involves addressing behavioral changes in addition to the movement disorder. Patients with PD are susceptible to any psychiatric condition seen in the general population; some disorders, such as depression and anxiety, may result from PD-related neuropathologi...

journal_title：Dialogues in clinical neuroscience

authors： Anderson KE

更新日期：2004-09-01 00:00:00

abstract：:In 2003, we proposed the hypersystemizing theory of autism. The theory proposes that the human mind possesses a systemizing mechanism (SM) that helps identify lawful regularities (often causal) that govern the input-operation-output workings of a system. The SM can be tuned to different levels, from low to high, with ...

journal_title：Dialogues in clinical neuroscience

authors： Baron-Cohen S,Lombardo MV

更新日期：2017-12-01 00:00:00

abstract：:Depressive disorders are a leading cause of disability worldwide and greatly impact morbidity, health care utilization, and medical costs. Major depression that does not resolve with adequate antidepressant treatment is termed treatment-resistant depression (TRD), There is no universally accepted definition of TRD and...

journal_title：Dialogues in clinical neuroscience

authors： Parikh RM,Lebowitz BD

更新日期：2004-03-01 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) may be associated with long-lasting psychological suffering, distressing psychosocial disability, markedly reduced health-related quality of life, and increased morbidity and mortality in a subgroup of individuals in the aftermath of serious traumatic events. Both etiopathogenesis...

journal_title：Dialogues in clinical neuroscience

authors： Kapfhammer HP

更新日期：2014-06-01 00:00:00

abstract：:Recent years have seen an explosive growth of interest in the application of imaging genetics to understand neurogenetic mechanisms of schizophrenia. Imaging genetics applies structural and functional neuroimaging to study subjects carrying genetic risk variants that relate to a psychiatric disorder. We review selecte...

journal_title：Dialogues in clinical neuroscience

authors： Meyer-Lindenberg A

更新日期：2010-01-01 00:00:00

abstract：:Recent research has overcome the old paradigms of the brain as an immunologically privileged organ, and of the exclusive role of neurotransmitters and neuropeptides as signal transducers in the central nervous system. Growing evidence suggests that the signal proteins of the immune system - the cytokines - are also in...

journal_title：Dialogues in clinical neuroscience

authors： Schwarz MJ

更新日期：2003-06-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a serious psychiatric disorder that affects approximately 2% of the populations of children and adults. Family aggregation studies have demonstrated that OCD is familial, and results from twin studies demonstrate that the familiality is due in part to genetic factors. Only three ...

journal_title：Dialogues in clinical neuroscience

authors： Pauls DL

更新日期：2010-01-01 00:00:00

abstract：:Brain plasticity is an intrinsic characteristic of the nervous system that allows continuous remodeling of brain functions in pathophysiological conditions. Although normal aging is associated with morphological modifications and decline of cerebral functions, brain plasticity is at least partially preserved in elderl...

journal_title：Dialogues in clinical neuroscience

authors： Chollet F

更新日期：2013-03-01 00:00:00

abstract：:The frontoparietal network is critical for our ability to coordinate behavior in a rapid, accurate, and flexible goal-driven manner. In this review, we outline support for the framing of the frontoparietal network as a distinct control network, in part functioning to flexibly interact with and alter other functional b...

journal_title：Dialogues in clinical neuroscience

authors： Marek S,Dosenbach NUF

更新日期：2018-06-01 00:00:00

abstract：:Increased physician prescribing of opioids to treat chronic nonprogressive pain has been accompanied by an increase in opioid addiction. Twin studies of opioid addiction are consistent with an inherited component of risk, approximately 50%. Several genome-wide association study (GWAS) reports indicate that genetic ris...

journal_title：Dialogues in clinical neuroscience

authors： Berrettini W

更新日期：2017-09-01 00:00:00

abstract：:Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on naturalistic stressors, pharmacological challenges, and genomic manip...

journal_title：Dialogues in clinical neuroscience

authors： Patchev VK,Patchev AV

更新日期：2006-01-01 00:00:00

abstract：:Epidemiological studies show that anxiety disorders are highly prevalent and an important cause of functional impairment; they constitute the most frequent menial disorders in the community. Phobias are the most common with the highest rates for simple phobia and agoraphobia. Panic disorder (PD) and obsessive-compulsi...

journal_title：Dialogues in clinical neuroscience

authors： Martin P

更新日期：2003-09-01 00:00:00

abstract：:Late-life depression (LLD) is a growing public and global health concern with diverse clinical manifestations and etiology. This literature review summarizes neuroimaging findings associated with depression in older adults and treatment-response variability. LLD has been associated with cerebral atrophy, diminished my...

journal_title：Dialogues in clinical neuroscience

authors： Agudelo C,Aizenstein HJ,Karp JF,Reynolds CF 3rd

更新日期：2015-06-01 00:00:00

abstract：:It is timely to consider the ethical and social questions raised by progress in pharmacogenomics, based on the current importance of pharmacogenomics for avoidance of predictable side effects of drugs, and for correct choice of medications in certain cancers. It has been proposed that the entire population be genotype...

journal_title：Dialogues in clinical neuroscience

authors： Gershon ES,Alliey-Rodriguez N,Grennan K

更新日期：2014-12-01 00:00:00

abstract：:Despite the fact that 50 years have passed since the Nazi regime and the Holocaust the psychic sequelae are far from being overcome. The majority of Holocaust survivors and World War II veterans still list their experiences as the "most significant stressors" of their lives. The literature provides ample evidence that...

journal_title：Dialogues in clinical neuroscience

authors： Barak Y,Szor H

更新日期：2000-03-01 00:00:00

abstract：:Partial remission from depression, with residual symptoms, is an important problem in depression. This paper reviews the frequency and features of this outcome, and its association with relapse. Residual symptoms occur in many depressed patients after acute treatment. They span the typical symptoms of depression, exce...

journal_title：Dialogues in clinical neuroscience

authors： Paykel ES

更新日期：2008-01-01 00:00:00

abstract：:It is clinically important to recognize both bipolar disorder and borderline personality disorder (BPD) in patients seeking treatment for depression, and it is important to distinguish between the two. Research considering whether BPD should be considered part of a bipolar spectrum reaches differing conclusions. We re...

journal_title：Dialogues in clinical neuroscience

authors： Zimmerman M,Morgan TA

更新日期：2013-06-01 00:00:00

abstract：:Development of the characteristics of social phobia often requires a diathesis in the form of a temperamental bias. A behavioral profile marked by vigorous motor activity and crying to unfamiliar stimuli at 4 months of age - called high reactivity- is characteristic of about 20% of healthy, Caucasian infants. This pat...

journal_title：Dialogues in clinical neuroscience

authors： Kagan J

更新日期：2002-09-01 00:00:00

abstract：:Mental disorders represent a significant public health burden worldwide due to their high prevalence, chronically disabling nature, and substantial impact on quality of life. Despite growing knowledge of the pathological mechanisms that underlie the development of these disorders, a high percentage of patients do not ...

journal_title：Dialogues in clinical neuroscience

authors： Scherma M,Muntoni AL,Riedel G,Fratta W,Fadda P

更新日期：2020-09-01 00:00:00

abstract：:Cognitive symptoms are a core feature of schizophrenia and are related to an unfavorable disease outcome. So far, there are no satisfactory pharmacological approaches to address cognitive symptoms. For some time now, aerobic exercise has been demonstrated in various trials to be a promising candidate for this indicati...

journal_title：Dialogues in clinical neuroscience

authors： Maurus I,Röh A,Falkai P,Malchow B,Schmitt A,Hasan A

更新日期：2019-09-01 00:00:00

abstract：:The insights of ethology-the science of animal behavior from a biological and psychological point of view-were incorporated in the 1950s by the British developmental psychiatrist, John Bowlby, into his attachment theory, which argued that a secure affective base in infancy was critical to the normal development of per...

journal_title：Dialogues in clinical neuroscience

authors： Cyrulnik B

更新日期：2005-01-01 00:00:00

abstract：:Sleep disorders in children and adolescents is a topic that has been, and remains, neglected in both public health education and professional training. Although much knowledge has been accumulated in recent times, it has been poorly disseminated and, therefore, relatively little is put into practice. Only some general...

journal_title：Dialogues in clinical neuroscience

authors： Stores G

更新日期：2009-01-01 00:00:00

abstract：:The construct of major depressive disorder makes no etiological assumptions about populations with diverse symptom clusters. "Depressed mood" and "loss of interest or pleasure in nearly all activities" are core features of major depressive episode, though a strong case can be made to pay increasing attention to sympto...

journal_title：Dialogues in clinical neuroscience

authors： Kennedy SH

更新日期：2008-01-01 00:00:00

abstract：:The validity of diagnostic definitions in psychiatry is directly related to the extent to which their etiology can be specified. However, since detailed knowledge of causal or susceptibility factors is lacking for most psychiatric disorders with a known or suspected familial-genetic origin, the current widely accepted...

journal_title：Dialogues in clinical neuroscience

authors： Maier W

更新日期：1999-12-01 00:00:00

abstract：:The first generation of antipsychotic drugs was discovered in the 1960s and 1970s, These agents were effective in treating psychosis, but were accompanied by significant side effects, including severe parkinsonism and akathisia. Second-generation antipsychotics were introduced in the 1990s, These drugs have at least e...

journal_title：Dialogues in clinical neuroscience

authors： Tamminga CA

更新日期：2000-09-01 00:00:00

abstract：:Despite pharmacologic advances, the treatment of schizophrenia remains a challenge, and suboptimal outcomes are still all too frequent. Although treatment goals of response, remission, and recovery have been defined more uniformly, a good "effectiveness" measure mapping onto functional outcomes is still lacking. Moreo...

journal_title：Dialogues in clinical neuroscience

authors： Kane JM,Correll CU

更新日期：2010-01-01 00:00:00

abstract：:Inborn errors of metabolism (IEMs) are particularly frequent as diseases of the nervous system. In the pediatric neurologic presentations of IEMs neurodevelopment is constantly disturbed and in fact, as far as biochemistry is involved, any kind of monogenic disease can become an IEM. Clinical features are very diverse...

journal_title：Dialogues in clinical neuroscience

authors： Saudubray JM,Garcia-Cazorla A

更新日期：2018-12-01 00:00:00