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The prevalence of anaemia depends on the definition: an example from the Aboriginal Birth Cohort Study.

Abstract：

OBJECTIVE:The cutoffs defining anaemia based on haemoglobin and haematocrit recommended by the World Health Organization (WHO) and the United States (US) are different. We compared the prevalences resulting from these definitions and explored the reasons for the variation observed. DESIGN:A cross-sectional survey within a cohort study of children recruited at birth at Royal Darwin Hospital. SETTING:Subjects were interviewed in their homes or other convenient location and had a blood sample drawn. SUBJECTS:Five hundred and seventeen Australian Aboriginal children aged 9-13 years inclusive. RESULTS:Depending on the criterion used, the prevalence of anaemia in the total group ranged between 6% (95% confidence interval: 4.1-8.4%) and 24.4% (20.7-28.3). Using the WHO criteria, girls aged 12-13 years were identified as a target group, having a two- to-six fold higher prevalence than the other groups. When compared to the US criteria, boys aged 12-13 years had the highest prevalence of anaemia, although this was not significant. Simulations show that the WHO cutoffs are based on inconsistent centiles of the age-sex haemoglobin and haematocrit distributions, and that this largely explains the discrepant results. CONCLUSIONS:This variability in definition could lead to inappropriate identification of target groups for intervention programmes.

journal_name

Eur J Clin Nutr

journal_title

European journal of clinical nutrition

authors

Mackerras D,Singh G

doi

10.1038/sj.ejcn.1602483

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

135-9

issue

1

eissn

0954-3007

issn

1476-5640

pii

1602483

journal_volume

61

pub_type

杂志文章

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