Antibodies against cell surface antigens as very potent immunological adjuvants.

abstract：:Salmonellae are commonly isolated from dogs. The number of dogs infected with Salmonella spp. is surprisingly high and greater than the incidence of clinical disease would suggest. Salmonellosis is common in greyhound kennels. Morbidity can approach 100% in puppies and the mortality ranges to nearly 40%. To date, ther...

journal_title：Vaccine

authors： McVey DS,Chengappa MM,Mosier DE,Stone GG,Oberst RD,Sylte MJ,Gabbert NM,Kelly-Aehle SM,Curtiss R

更新日期：2002-02-22 00:00:00

abstract：:A growing number of people use the Internet to obtain health information, including information about vaccines. Websites that allow and promote interaction among users are an increasingly popular source of health information. Users of such so-called Web 2.0 applications (e.g. social media), while still in the minority...

journal_title：Vaccine

authors： Betsch C,Brewer NT,Brocard P,Davies P,Gaissmaier W,Haase N,Leask J,Renkewitz F,Renner B,Reyna VF,Rossmann C,Sachse K,Schachinger A,Siegrist M,Stryk M

更新日期：2012-05-28 00:00:00

abstract：:A gene encoding the mature Escherichia coli heat-labile enterotoxin B subunit (LTB) was introduced in a vector pNU212 and expressed at high levels in Bacillus brevis HPD31. The maximum amount of recombinant LTB (rLTB) secreted into the modified 5PY medium containing erythromycin was about 350 mg l(-1) when cultivated ...

journal_title：Vaccine

authors： Kozuka S,Yasuda Y,Isaka M,Masaki N,Taniguchi T,Matano K,Moriyama A,Ohkuma K,Goto N,Udaka S,Tochikubo K

更新日期：2000-03-06 00:00:00

abstract：:This study sought to explore how parents respond to competing media messages about vaccine safety. Six focus groups with mothers of infants were shown television vignettes of typical pro- and anti-vaccination claims. Thematic analysis of transcripts was undertaken. Mothers expressed surprise and concern about alleged ...

journal_title：Vaccine

authors： Leask J,Chapman S,Hawe P,Burgess M

更新日期：2006-11-30 00:00:00

abstract：:A multi-component vaccine has been defined, which contains six different synthetic 24- to 32-amino acid lipopeptides derived from the sequence of HIV-1 proteins. The physicochemical properties of the lipopeptide components were compatible with multi-dimensional analysis, using RP-HPLC, Edman sequencing, electrospray m...

journal_title：Vaccine

authors： Klinguer C,David D,Kouach M,Wieruszeski JM,Tartar A,Marzin D,Levy JP,Gras-Masse H

更新日期：1999-09-01 00:00:00

abstract：:Polysaccharides (PSs) derived from Streptococcus pneumoniae include more than 90 serotypes and differ greatly in their immunogenicity. In addition, immunization with PSs does not induce high affinity antibody production and no memory B-cells are generated. Coupling PSs to carrier proteins has been reported to induce B...

journal_title：Vaccine

authors： Libon C,Haeuw JF,Crouzet F,Mugnier C,Bonnefoy JY,Beck A,Corvaïa N

更新日期：2002-05-22 00:00:00

abstract：:Increases in global travel, trade and urbanisation are leading to greater incidence of zoonotic disease, and livestock are often a key link in the spread of disease to humans. As such, livestock vaccination strategies, as a part of broader biosecurity solutions, are critical to both animal and human health. Importantl...

journal_title：Vaccine

authors： Layton DS,Choudhary A,Bean AGD

更新日期：2017-10-20 00:00:00

abstract：:Protective mechanisms underlying the responses to mucosal vaccination are not yet clearly defined. Using the natural mouse pneumovirus pathogen, pneumonia virus of mice (PVM), we explore responses of wild type and interferon-gamma (IFNgamma) receptor gene-deleted mice to virulent challenge after mucosal vaccination wi...

journal_title：Vaccine

authors： Ellis JA,Martin BV,Waldner C,Dyer KD,Domachowske JB,Rosenberg HF

更新日期：2007-01-22 00:00:00

abstract：:Immunization with amyloid-beta (Abeta) peptide reduces amyloid load in animal studies and in humans; however clinical trials resulted in the development of a pro-inflammatory cellular response to Abeta. Apoptosis has been employed to stimulate humoral and Th2-biased cellular immune responses. Thus, we sought to invest...

journal_title：Vaccine

authors： DaSilva KA,Brown ME,McLaurin J

更新日期：2009-02-25 00:00:00

abstract：:Tuberculosis (TB) is the biggest cause of human mortality from an infectious disease. The only vaccine currently available, bacille Calmette-Guérin (BCG), demonstrates some protection against disseminated disease in childhood but very variable efficacy against pulmonary disease in adults. A greater understanding of pr...

journal_title：Vaccine

authors： Bull NC,Kaveh DA,Garcia-Pelayo MC,Stylianou E,McShane H,Hogarth PJ

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:In most low and middle-income countries (LMIC), vaccines are primarily distributed by routine immunization services (RI) at health facilities. Additional opportunities for vaccination are also provided through mass vaccination campaigns, conducted periodically as part of disease-specific initiatives. It is u...

journal_title：Vaccine

authors： Helleringer S,Asuming PO,Abdelwahab J

更新日期：2016-07-19 00:00:00

abstract：:The aims of this study were to evaluate the impact of hepatitis B vaccination on the changing pattern of HBV infection in a former hyperendemic area (Afragola, South Italy), and to assess the long-term persistence of anti-HBs in two cohorts of individuals vaccinated as infants 18 and 23 years ago. Our data shows a sig...

journal_title：Vaccine

authors： Da Villa G,Romanò L,Sepe A,Iorio R,Paribello N,Zappa A,Zanetti AR

更新日期：2007-04-20 00:00:00

abstract：:In 2003-2004, a national measles seroprevalence study was conducted in Italy and data were analysed by using both commercial ELISA cut-off, and by applying a mixture model. Results of the two methods were compared and interpreted in the light of measles incidence, vaccination coverage and previous seroprevalence data....

journal_title：Vaccine

authors： Rota MC,Massari M,Gabutti G,Guido M,De Donno A,Ciofi degli Atti ML

更新日期：2008-08-12 00:00:00

abstract：:HPV vaccines are highly immunogenic. A two-dose schedule for 9-14 year-old is recommended. However, no data exist regarding the impact of age, menarche status and body mass index (BMI) on the immune response to a two-dose schedule. In this post-hoc analysis, we present antibody titers to HPV6/11/16/18 in 9-13 year-old...

journal_title：Vaccine

authors： Sauvageau C,Gilca V,Donken R,Fan SY,Ogilvie G,Dobson S

更新日期：2019-11-20 00:00:00

abstract：:Rotavirus diarrhoea is associated with high childhood mortality in developing countries. A new vaccine was recently licensed in Mexico. The objective of this study was to assess the effectiveness of routine childhood vaccination by this new vaccine in a developing country. We constructed a decision tree to compare two...

journal_title：Vaccine

authors： Melliez H,Boelle PY,Baron S,Mouton Y,Yazdanpanah Y

更新日期：2007-01-04 00:00:00

abstract：:The immunogenicity and reactogenicity of a booster dose of enhanced potency inactivated polio vaccine (EIPV) were evaluated in 492 healthy 12 year old adolescents. The booster was administered at the same time as the HBV vaccine compulsory in Italy at this age. Blood samples and questionnaires on reactogenicity were c...

journal_title：Vaccine

authors： Pregliasco F,Grilli G,Andreassi A,D'Addezio E,Vacca F,Squarcione S,Biasio LR,Profeta M

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:As part of the U.S. Department of Health and Human Services (HHS) Pandemic Influenza Plan preparedness and response strategy, the National Pre-Pandemic Influenza Vaccine Stockpile (NPIVS) program was established by the Biomedical Advanced Research and Development Authority (BARDA) in 2005 with the goal of bu...

journal_title：Vaccine

authors： Oshansky CM,Zhou J,Gao Y,Schweinle JE,Biscardi K,DeBeauchamp J,Pavetto C,Wollish A,BRITE Study Coordination Team.,Webby RJ,Cioce V,Donis RO,Bright RA

更新日期：2019-01-14 00:00:00

abstract：:Trehalose-6,6'-dimycolate (TDM) and its monosaccharide-type analogues were synthesized, and their lethal and adjuvant activities were examined in mice. All the monosaccharide-type analogues with a glucose or N-acetylglucosamine moiety were devoid of lethal toxicity to mice; in particular, D-GlcNAcM(1-deoxy) and D-GlcN...

journal_title：Vaccine

authors： Sakurai T,Saiki I,Ishida H,Takeda K,Azuma I

更新日期：1989-06-01 00:00:00

abstract：:Domestic dogs constitute the main reservoir of Leishmania infantum and play a key role in transmission to humans. The main tool for controlling infection spread is a safe and effective vaccine, as successful immunization of dogs could significantly reduce the incidence of human visceral leishmaniosis (VL) and is the m...

journal_title：Vaccine

authors： Cacheiro-Llaguno C,Parody N,Renshaw-Calderón A,Osuna C,Alonso C,Carnés J

更新日期：2020-01-22 00:00:00

abstract：:Mutations arising in neutralizing epitopes of hepatitis C virus may play a role in the ability of the virus to escape control by neutralizing antibodies and in the establishment of chronic infections. An amino-acid substitution, Q412H, within a major conserved neutralization epitope EP I (aa 412-426) in the E2 glycopr...

journal_title：Vaccine

authors： Duan H,Struble E,Zhong L,Mihalik K,Major M,Zhang P,Feinstone S,Feigelstock D

更新日期：2010-06-07 00:00:00

abstract：:The ELISA method was used to titrate the humoral immune response in vaccinated mice. When mice were given two doses of a heat-killed salmonella vaccine 6 days apart, there was a steady but low-level increase of antibody synthesis. In contrast, if a booster vaccination was administered 21 days after the primary inocula...

journal_title：Vaccine

authors： Xu HR,Hsu HS,Moncure CW,King RA

更新日期：1993-01-01 00:00:00

abstract：:In Portugal, the 7-valent pneumococcal conjugate vaccine (PCV7) was not introduced in the national immunization plan but was commercially available between 2001 and 2010. We studied serotype distribution and antibiotic susceptibility of Streptococcus pneumoniae carried by children in 2009 and 2010. Vaccination with PC...

journal_title：Vaccine

authors： Nunes S,Félix S,Valente C,Simões AS,Tavares DA,Almeida ST,Paulo AC,Brito-Avô A,de Lencastre H,Sá-Leão R

更新日期：2016-03-29 00:00:00

abstract：:The safety and immunogenicity of a new formulation of the inactivated hepatitis A vaccine, Avaxim, was evaluated in 189 children, aged 18 months to 15 years in a monocentric, open trial. Two vaccinations were given six months apart. Enrollment was balanced within three age groups: 18 months to 3 years, 4-8 years and 9...

journal_title：Vaccine

authors： Dagan R,Greenberg D,Goldenbertg-Gehtman P,Vidor E,Briantais P,Pinsk V,Athias O,Dumas R

更新日期：1999-04-09 00:00:00

abstract：:Vaccination with viral-based vaccines continues to hold promise for the prevention of malaria. Whilst antigen-specific T cell responses are considered a major aim of such an approach, a role for induced NK cells as anti-malarial effector cells, or in shaping T cell responses, has received less attention. In this study...

journal_title：Vaccine

authors： Berthoud TK,Fletcher H,Porter D,Thompson F,Hill AV,Todryk SM

更新日期：2009-12-10 00:00:00

abstract：:Nasal mucosal barrier is a key impediment for the absorption of influenza whole inactivated virus (WIV) intranasal vaccine. Yet it is still unclear how WIV cross the epithelial cells (ECs) in nasal cavity. Here, in vitro, a coculture system was well established, consisting of surrogate nasal ECs (Calu-3) and dendritic...

journal_title：Vaccine

authors： Qin T,Yin Y,Wang X,Liu H,Lin J,Yu Q,Yang Q

更新日期：2015-03-10 00:00:00

abstract：UNLABELLED:The Internet contains a large amount of useful information on many subjects, but also information of doubtful quality. To help identify Web sites on vaccine safety that fulfil good practice, the Global Advisory Committee on Vaccine Safety of the World Health Organization (WHO) has published criteria to which...

journal_title：Vaccine

authors： Martínez-Mora M,Alvarez-Pasquín MJ,Rodríguez-Salvanés F

更新日期：2008-12-09 00:00:00

abstract：:Vaccination is the best available measure of limiting the impact of the next influenza pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer and should elicit strong mucosal and systemic immune responses. Production of influenza subunit antigen in transient plant expression systems is ...

journal_title：Vaccine

authors： Madhun AS,Haaheim LR,Nøstbakken JK,Ebensen T,Chichester J,Yusibov V,Guzman CA,Cox RJ

更新日期：2011-07-12 00:00:00

abstract：BACKGROUND:The combined hexavalent diphtheria-tetanus-pertussis-hepatitis B-inactivated poliomyelitis - Haemophilus influenzae type b conjugate vaccine (Infanrix hexa™; DTPa-HBV-IPV/Hib: GlaxoSmithKline Vaccines) induces robust responses to the HBV component when administered at 3, 5 and 11-12 months of age. We assesse...

journal_title：Vaccine

authors： Avdicova M,Crasta PD,Hardt K,Kovac M

更新日期：2015-05-28 00:00:00

abstract：OBJECTIVE:To systematically review literature on uptake and timeliness of diphtheria-tetanus-pertussis, measles-mumps-rubella, and/or polio-containing vaccines ininfants who were born preterm, with a low birth weight, and/or with chronic health conditions that were diagnosed within the first 6 months of life. METHODS:...

journal_title：Vaccine

authors： Walker EJ,MacDonald NE,Islam N,Le Saux N,Top KA,Fell DB

更新日期：2019-03-22 00:00:00

abstract：:A booster dose of a formalin-inactivated, cell culture-propagated Rift Valley fever vaccine (TSI-GSD-200) was administered without significant reactogenicity to 60 volunteers 18 months after they received a three dose primary series. Blood was drawn for serological testing prior to boosting and 10, 49, and 180 days th...

journal_title：Vaccine

authors： Kark JD,Aynor Y,Peters CJ

更新日期：1985-06-01 00:00:00