Attentional modulation in the detection of irrelevant deviance: a simultaneous ERP/fMRI study.


:Little is known about the neural mechanisms that control attentional modulation of deviance detection in the auditory modality. In this study, we manipulated the difficulty of a primary task to test the relation between task difficulty and the detection of infrequent, task-irrelevant deviant (D) tones (1,300 Hz) presented among repetitive standard (S) tones (1,000 Hz). Simultaneous functional magnetic resonance imaging (fMRI)/event-related potentials (ERPs) were recorded from 21 subjects performing a two-alternative forced-choice duration discrimination task (short and long tones of equal probability). The duration of the short tone was always 50 msec. The duration of the long tone was 100 msec in the easy task and 60 msec in the difficult task. As expected, response accuracy decreased and response time (RT) increased in the difficult compared with the easy task. Performance was also poorer for D than for S tones, indicating distraction by task-irrelevant frequency information on trials involving D tones. In the difficult task, an amplitude increase was observed in the difference waves for N1 and P3a, ERP components associated with increased attention to deviant sounds. The mismatch negativity (MMN) response, associated with passive deviant detection, was larger in the easy task, demonstrating the susceptibility of this component to attentional manipulations. The fMRI contrast D > S in the difficult task revealed activation on the right superior temporal gyrus (STG) and extending ventrally into the superior temporal sulcus, suggesting this region's involvement in involuntary attention shifting toward unattended, infrequent sounds. Conversely, passive deviance detection, as reflected by the MMN, was associated with more dorsal activation on the STG. These results are consistent with the view that the dorsal STG region is responsive to mismatches between the memory trace of the standard and the incoming deviant sound, whereas the ventral STG region is activated by involuntary shifts of attention to task-irrelevant auditory features.


J Cogn Neurosci


Sabri M,Liebenthal E,Waldron EJ,Medler DA,Binder JR




Has Abstract


2006-05-01 00:00:00












  • The impact of semantic memory loss on phonological representations.

    abstract::Abstract Three patients with semantic dementia, involving progressive deterioration of semantic memory, performed immediate serial recall of short sequences of familiar words. On the basis of their performance in other tasks of word comprehension and production, the stimuli were selected individually for each patient ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Patterson K,Graham N,Hodges JR

    更新日期:1994-01-01 00:00:00

  • Neural organization of linguistic short-term memory is sensory modality-dependent: evidence from signed and spoken language.

    abstract::Despite decades of research, there is still disagreement regarding the nature of the information that is maintained in linguistic short-term memory (STM). Some authors argue for abstract phonological codes, whereas others argue for more general sensory traces. We assess these possibilities by investigating linguistic ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Pa J,Wilson SM,Pickell H,Bellugi U,Hickok G

    更新日期:2008-12-01 00:00:00

  • Images of illusory motion in primary visual cortex.

    abstract::Illusory motion can be generated by successively flashing a stationary visual stimulus in two spatial locations separated by several degrees of visual angle. In appropriate conditions, the apparent motion is indistinguishable from real motion: The observer experiences a luminous object traversing a continuous path fro...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Larsen A,Madsen KH,Lund TE,Bundesen C

    更新日期:2006-07-01 00:00:00

  • Modulation of the auditory cortex during speech: an MEG study.

    abstract::Several behavioral and brain imaging studies have demonstrated a significant interaction between speech perception and speech production. In this study, auditory cortical responses to speech were examined during self-production and feedback alteration. Magnetic field recordings were obtained from both hemispheres in s...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Houde JF,Nagarajan SS,Sekihara K,Merzenich MM

    更新日期:2002-11-15 00:00:00

  • Involvement of the superior temporal cortex and the occipital cortex in spatial hearing: evidence from repetitive transcranial magnetic stimulation.

    abstract::The processing of auditory spatial information in cortical areas of the human brain outside of the primary auditory cortex remains poorly understood. Here we investigated the role of the superior temporal gyrus (STG) and the occipital cortex (OC) in spatial hearing using repetitive transcranial magnetic stimulation (r...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Lewald J,Meister IG,Weidemann J,Töpper R

    更新日期:2004-06-01 00:00:00

  • Event-related brain potentials following incorrect feedback in a time-estimation task: evidence for a "generic" neural system for error detection.

    abstract::We examined scalp-recorded event-related potentials following feedback stimuli in a time-estimation task. Six hundred msec after indicating the end of a 1 sec interval, subjects received a visual, auditory, or somatosensory stimulus that indicated whether the interval they had produced was correct. Following feedback ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Miltner WH,Braun CH,Coles MG

    更新日期:1997-11-01 00:00:00

  • Large-scale Functional Integration, Rather than Functional Dissociation along Dorsal and Ventral Streams, Underlies Visual Perception and Action.

    abstract::Visual dual-stream theory posits that two distinct neural pathways of specific functional significance originate from primary visual areas and reach the inferior temporal (ventral) and posterior parietal areas (dorsal). However, there are several unresolved questions concerning the fundamental aspects of this theory. ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Ray D,Hajare N,Roy D,Banerjee A

    更新日期:2020-05-01 00:00:00

  • Sublexical properties of spoken words modulate activity in Broca's area but not superior temporal cortex: implications for models of speech recognition.

    abstract::Many models of spoken word recognition posit that the acoustic stream is parsed into phoneme level units, which in turn activate larger representations [McClelland, J. L., & Elman, J. L. The TRACE model of speech perception. Cognitive Psychology, 18, 1-86, 1986], whereas others suggest that larger units of analysis ar...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Vaden KI Jr,Piquado T,Hickok G

    更新日期:2011-10-01 00:00:00

  • Biased Competition during Long-term Memory Formation.

    abstract::A key task for the brain is to determine which pieces of information are worth storing in memory. To build a more complete representation of the environment, memory systems may prioritize new information that has not already been stored. Here, we propose a mechanism that supports this preferential encoding of new info...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Hutchinson JB,Pak SS,Turk-Browne NB

    更新日期:2016-01-01 00:00:00

  • The magnitude representation of small and large symbolic numbers in the left and right hemisphere: an event-related fMRI study.

    abstract::Numbers are known to be processed along the left and right intraparietal sulcus. The present study investigated hemispheric differences between the magnitude representation of small and large symbolic numbers. To this purpose, an fMRI adaptation paradigm was used, where the continuous presentation of a habituation num...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Notebaert K,Nelis S,Reynvoet B

    更新日期:2011-03-01 00:00:00

  • Capture by Context Elements, Not Attentional Suppression of Distractors, Explains the PD with Small Search Displays.

    abstract::Top-down control of attention allows us to resist attentional capture by salient stimuli that are irrelevant to our current goals. Recently, it was proposed that attentional suppression of salient distractors contributes to top-down control by biasing attention away from the distractor. With small search displays, att...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Kerzel D,Burra N

    更新日期:2020-06-01 00:00:00

  • ERP evidence of morphological analysis from orthography: a masked priming study.

    abstract::There is broad consensus that the visual word recognition system is sensitive to morphological structure (e.g., "hunter" = "hunt" + "er"). Moreover, it has been assumed that the analysis of morphologically complex words (e.g., "hunter") occurs only if the meaning of the complex form can be derived from the meanings of...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Lavric A,Clapp A,Rastle K

    更新日期:2007-05-01 00:00:00

  • Episodic action memory for real objects: an ERP investigation with perform, watch, and imagine action encoding tasks versus a non-action encoding task.

    abstract::Cognitive research shows that people typically remember actions they perform better than those that they only watch or imagine doing, but also at times misremember doing actions they merely imagined or planned to do (source memory errors). Neural research suggests some overlap between brain regions engaged during acti...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Senkfor AJ,Van Petten C,Kutas M

    更新日期:2002-04-01 00:00:00

  • Tracking Keystroke Sequences at the Cortical Level Reveals the Dynamics of Serial Order Production.

    abstract::Response selection is often studied by examining single responses, although most actions are performed within an overarching sequence. Understanding processes that order and execute items in a sequence is thus essential to give a complete picture of response selection. In this study, we investigate response selection ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Pinet S,Dell GS,Alario FX

    更新日期:2019-07-01 00:00:00

  • Subordinate categorization enhances the neural selectivity in human object-selective cortex for fine shape differences.

    abstract::There is substantial evidence that object representations in adults are dynamically updated by learning. However, it is not clear to what extent these effects are induced by active processing of visual objects in a particular task context on top of the effects of mere exposure to the same objects. Here we show that th...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Gillebert CR,Op de Beeck HP,Panis S,Wagemans J

    更新日期:2009-06-01 00:00:00

  • Attentional modulation of unconscious "automatic" processes: evidence from event-related potentials in a masked priming paradigm.

    abstract::Automatic processes are usually thought to occur independently of any cognitive resources. This traditional view has been recently challenged by showing that temporal attention to a target stimulus is a prerequisite for "automatic" response priming. The event-related potential (ERP) study reported here extends this re...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Kiefer M,Brendel D

    更新日期:2006-02-01 00:00:00

  • Encoding of Predictable and Unpredictable Stimuli by Inferior Temporal Cortical Neurons.

    abstract::Animals and humans learn statistical regularities that are embedded in sequences of stimuli. The neural mechanisms of such statistical learning are still poorly understood. Previous work in macaque inferior temporal (IT) cortex demonstrated suppressed spiking activity to visual images of a sequence in which the stimul...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Kumar S,Kaposvari P,Vogels R

    更新日期:2017-08-01 00:00:00

  • Enhancement of metabolic activity in the diencephalon of monkeys performing working memory task: a 2-deoxyglucose study in behaving rhesus monkeys.

    abstract::The 2-deoxyglucose (2-DG) method was used to study the effect of working memory processing on local cerebral glucose utilization (LCGU) in the diencephalon of the rhesus monkey. Monkeys were given [(14)C]2-DG while performing either one of three tasks that engaged working memory (WORK group) or one of two control task...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Friedman HR,Janas JD,Goldman-Rakic PS

    更新日期:1990-01-01 00:00:00

  • FM-selective networks in human auditory cortex revealed using fMRI and multivariate pattern classification.

    abstract::Frequency modulation (FM) is an acoustic feature of nearly all complex sounds. Directional FM sweeps are especially pervasive in speech, music, animal vocalizations, and other natural sounds. Although the existence of FM-selective cells in the auditory cortex of animals has been documented, evidence in humans remains ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Hsieh IH,Fillmore P,Rong F,Hickok G,Saberi K

    更新日期:2012-09-01 00:00:00

  • Retrieval from episodic memory: neural mechanisms of interference resolution.

    abstract::Selectively retrieving a target memory among related memories requires some degree of inhibitory control over interfering and competing memories, a process assumed to be supported by inhibitory mechanisms. Evidence from behavioral studies suggests that such inhibitory control can lead to subsequent forgetting of the i...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Wimber M,Rutschmann RM,Greenlee MW,Bäuml KH

    更新日期:2009-03-01 00:00:00

  • Optimizing design efficiency of free recall events for FMRI.

    abstract::Free recall is a fundamental paradigm for studying memory retrieval in the context of minimal cue support. Accordingly, free recall has been extensively studied using behavioral methods. However, the neural mechanisms that support free recall have not been fully investigated due to technical challenges associated with...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Oztekin I,Long NM,Badre D

    更新日期:2010-10-01 00:00:00

  • An Association between Auditory-Visual Synchrony Processing and Reading Comprehension: Behavioral and Electrophysiological Evidence.

    abstract::The perceptual system integrates synchronized auditory-visual signals in part to promote individuation of objects in cluttered environments. The processing of auditory-visual synchrony may more generally contribute to cognition by synchronizing internally generated multimodal signals. Reading is a prime example becaus...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Mossbridge J,Zweig J,Grabowecky M,Suzuki S

    更新日期:2017-03-01 00:00:00

  • Transcranial Cerebellar Direct Current Stimulation Enhances Verb Generation but Not Verb Naming in Poststroke Aphasia.

    abstract::Although the role of the cerebellum in motor function is well recognized, its involvement in the lexical domain remains to be further elucidated. Indeed, it has not yet been clarified whether the cerebellum is a language structure per se or whether it contributes to language processing when other cognitive components ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,随机对照试验


    authors: Marangolo P,Fiori V,Caltagirone C,Pisano F,Priori A

    更新日期:2018-02-01 00:00:00

  • Behavioral and electrophysiological evidence of a right hemisphere bias for the influence of negative emotion on higher cognition.

    abstract::We examined how responses to aversive pictures affected performance and stimulus-locked event-related potentials (ERPs) recorded during a demanding cognitive task. Numeric Stroop stimuli were brief ly presented to either left or right visual hemifield (LVF and RVF, respectively) after a centrally presented aversive or...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Simon-Thomas ER,Role KO,Knight RT

    更新日期:2005-03-01 00:00:00

  • Rehearsing biological motion in working memory: an EEG study.

    abstract::Holding biological motion (BM), the movements of animate entities, in working memory (WM) is important to our daily social life. However, how BM is maintained in WM remains unknown. The current study investigated this issue and hypothesized that, analogous to BM perception, the human mirror neuron system (MNS) is invo...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Gao Z,Bentin S,Shen M

    更新日期:2015-01-01 00:00:00

  • Leveling the Field for a Fairer Race between Going and Stopping: Neural Evidence for the Race Model of Motor Inhibition from a New Version of the Stop Signal Task.

    abstract::The stop signal task (SST) is the gold standard experimental model of inhibitory control. However, neither SST condition-contrast (stop vs. go, successful vs. failed stop) purely operationalizes inhibition. Because stop trials include a second, infrequent signal, the stop versus go contrast confounds inhibition with a...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Dykstra T,Waller DA,Hazeltine E,Wessel JR

    更新日期:2020-04-01 00:00:00

  • To look or not to look? Typical and atypical development of oculomotor control.

    abstract::The ability to inhibit saccades toward suddenly appearing peripheral stimuli (prosaccades) and direct them to contralateral locations instead (antisaccades) is a crucial marker of eye movement control. Typically developing infants as young as 4-month-olds can learn to inhibit reflexive saccades to peripheral stimuli, ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Scerif G,Karmiloff-Smith A,Campos R,Elsabbagh M,Driver J,Cornish K

    更新日期:2005-04-01 00:00:00

  • Unconscious priming requires early visual cortex at specific temporal phases of processing.

    abstract::Although examples of unconscious shape priming have been well documented, whether such priming requires early visual cortex (V1/V2) has not been established. In the current study, we used TMS of V1/V2 at varying temporal intervals to suppress the visibility of preceding shape primes while the interval between primes a...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Persuh M,Ro T

    更新日期:2013-09-01 00:00:00

  • Minimal Recognizable Configurations Elicit Category-selective Responses in Higher Order Visual Cortex.

    abstract::Visual object recognition is performed effortlessly by humans notwithstanding the fact that it requires a series of complex computations, which are, as yet, not well understood. Here, we tested a novel account of the representations used for visual recognition and their neural correlates using fMRI. The rationale is b...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Holzinger Y,Ullman S,Harari D,Behrmann M,Avidan G

    更新日期:2019-09-01 00:00:00

  • Transcranial magnetic stimulation in a finger-tapping task separates motor from timing mechanisms and induces frequency doubling.

    abstract::We study the interplay between motor programs and their timing in the brain by using precise pulses of transcranial magnetic stimulation (TMS) applied to the primary motor cortex. The movement of the finger performing a tapping task is periodically perturbed in synchronization with a metronome. TMS perturbation can pr...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章


    authors: Levit-Binnun N,Handzy NZ,Peled A,Modai I,Moses E

    更新日期:2007-05-01 00:00:00