Eosinophilic esophagitis in adults: what is the clinical significance?


:Eosinophilic esophagitis is a condition that is being increasingly recognized in adults. The main presenting symptoms are dysphagia (93 %), food impaction (62 %), and heartburn (24 %). A history of allergy is obtained in 52 % of patients and peripheral eosinophilia is found in 31 % of patients with this condition. Esophageal manometric studies have provided evidence of a nonspecific motility disorder in 40 % of patients. Endoscopic findings include mucosal fragility or edema (59 %), solitary or multiple concentric rings (49 %), strictures (40 %), whitish pinpoint exudates or papules (16 %), and a small-caliber esophagus (5 %); 9 % of patients present with a normal endoscopy. Esophageal dilation in adults with eosinophilic esophagitis has limited efficacy and is associated with an increased complication rate compared with dilation in patients with benign strictures. The administration of inhaled or systemic corticosteroids results in symptomatic improvement in nearly 95 % of patients. A trial with corticosteroids before bougienage may reduce active inflammation and therefore the complication rate of the procedure.






Sgouros SN,Bergele C,Mantides A




Has Abstract


2006-05-01 00:00:00












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    pub_type: 杂志文章


    authors: Satake H,Yano T,Muto M,Minashi K,Yoda Y,Kojima T,Oono Y,Ikematsu H,Aoyama I,Morita S,Miyamoto S,Fujii S,Yoshizawa A,Ochiai A,Hayashi R,Kaneko K

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    pub_type: 杂志文章,多中心研究


    authors: Marusch F,Koch A,Schmidt U,Zippel R,Kuhn R,Wolff S,Pross M,Wierth A,Gastinger I,Lippert H

    更新日期:2002-05-01 00:00:00

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    pub_type: 杂志文章


    authors: Ujszászy L,Prónay G,Nagy G,Kovács J,Libor J,Minik K

    更新日期:1985-05-01 00:00:00

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    pub_type: 杂志文章


    authors: Sekiguchi M,Suzuki H,Oda I,Abe S,Nonaka S,Yoshinaga S,Taniguchi H,Sekine S,Kushima R,Saito Y

    更新日期:2013-09-01 00:00:00

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    pub_type: 临床试验,杂志文章


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    更新日期:2005-05-01 00:00:00

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    pub_type: 杂志文章


    authors: Eluri S,Corder SR,Kim E,Tappata M,Reed CC,Shaheen NJ,Dellon ES

    更新日期:2020-10-06 00:00:00

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    更新日期:2015-11-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


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    更新日期:2001-08-01 00:00:00

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    pub_type: 杂志文章


    authors: Schimanski U,Stiehl A,Stremmel W,Theilmann L

    更新日期:1996-05-01 00:00:00

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    authors: Chen YS,Den BX,Huang BI,Xu LZ

    更新日期:1986-07-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Krugliak P,Ziff B,Rusabrov Y,Rosenthal A,Fich A,Gurman GM

    更新日期:2000-09-01 00:00:00

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    pub_type: 临床试验,杂志文章


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    更新日期:2002-10-01 00:00:00

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    pub_type: 杂志文章


    authors: Arul GS,Rooney PS,Gregson R,Steele RJ

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    pub_type: 杂志文章


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    pub_type: 杂志文章,多中心研究,随机对照试验


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    更新日期:2013-12-01 00:00:00

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    authors: Hordijk ML,Kok TC,Wilson JH,Mulder AH

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    pub_type: 杂志文章


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    pub_type: 临床试验,杂志文章,多中心研究


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    更新日期:2013-01-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2017-06-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:1986-03-01 00:00:00

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    abstract:: ...


    pub_type: 杂志文章


    authors: Mannami T,Fujiwara N,Ikeda G,Mishima T,Kuroi T,Muraoka T,Ohtawa Y

    更新日期:2019-02-01 00:00:00

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    pub_type: 杂志文章


    authors: Böhm G,Mossdorf A,Klink C,Klinge U,Jansen M,Schumpelick V,Truong S

    更新日期:2010-07-01 00:00:00

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    pub_type: 杂志文章


    authors: Irino T,Nunobe S,Hiki N,Yamamoto Y,Hirasawa T,Ohashi M,Fujisaki J,Sano T,Yamaguchi T

    更新日期:2015-04-01 00:00:00

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    pub_type: 杂志文章


    authors: Boivin ML,Lochs H,Voderholzer WA

    更新日期:2005-09-01 00:00:00

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    pub_type: 杂志文章,评审


    authors: Rösch T

    更新日期:1998-11-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2012-06-01 00:00:00

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    pub_type: 杂志文章,多中心研究,随机对照试验


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