A dose-response model for the conventional phototherapy of the newborn.

Abstract:

:Jaundice of the newborn is a common problem as a consequence of the rapid increment of blood bilirubin in the first days of live. In most cases, it is considered a physiological transient situation, but unmanaged hyperbilirubinemia can lead to death or serious injuries for the survivors. For decades, phototherapy has been used as the main method for prevention and treatment of hyperbilirubinaemia of the newborn. This work aims at finding a predictive model for the decrement of blood bilirubin for patients submitted to conventional phototherapy. Data from the phototherapy of 90 term newborns were collected and used in a multiple regression method. A rigorous statistical analysis was done in order to guarantee a correct and valid model. The obtained model was able to explain 78% of the variation of the dependent variable. We show that it is possible to predict the total serum bilirubin of the patient under conventional phototherapy by knowing its birth weight, bilirubin level at the beginning of treatment and the radiant energy density (dose). Besides, it is possible to infer the time necessary for a given decrement of bilirubin, under approximately constant irradiance. Statistical analysis of the obtained model shows that it is valid for several ranges of birth weight, initial bilirubin level, and radiant energy density. It is expected that the proposed model can be useful in the clinical management of hyperbilirubinemia of the newborn.

journal_name

J Clin Monit Comput

authors

Osaku NO,Lopes HS

doi

10.1007/s10877-006-9016-1

subject

Has Abstract

pub_date

2006-06-01 00:00:00

pages

159-64

issue

3

eissn

1387-1307

issn

1573-2614

journal_volume

20

pub_type

临床试验,杂志文章
  • Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise.

    abstract::Bioreactance is a novel non-invasive method for cardiac output measurement that involves the analysis of blood flow-dependent changes in the phase shifts of electrical currents applied across the chest. The present study (1) compared resting and exercise cardiac outputs determined by bioreactance and bioimpedance meth...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-012-9334-4

    authors: Jakovljevic DG,Moore S,Hallsworth K,Fattakhova G,Thoma C,Trenell MI

    更新日期:2012-04-01 00:00:00

  • Leakage of sevoflurane from vaporizer detected by air monitoring system: a case report.

    abstract::Leakage of inhalational anesthetic gases is an important issue not only to staff health but awareness during general anesthesia. After inhalation of sevoflurane commenced, the audible and visible alarm of our custom-made air monitoring system was activated. The system measured 2-4 ppm of sevoflurane. A thorough search...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-013-9479-9

    authors: Tanaka M,Yamaura K,Higashi M,Hoka S

    更新日期:2013-12-01 00:00:00

  • Composite-, plain-auditory evoked potentials index and bispectral index to measure the effects of sevoflurane.

    abstract::The composite auditory evoked potentials index (cAAI) uses both cortical electroencephalogram (EEG) and response to auditory stimuli, while the bispectral index (BIS) uses only the cortical EEG and auditory evoked potentials index (AAI) uses only response to auditory stimuli. We expected that the cAAI was more useful ...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10877-013-9441-x

    authors: Nishiyama T

    更新日期:2013-06-01 00:00:00

  • Validation of an automated system for detecting ineffective triggering asynchronies during mechanical ventilation: a retrospective study.

    abstract::We compare the sensitivity and specificity of clinician visual waveform analysis against an automated system's waveform analysis in detecting ineffective triggering in mechanically ventilated intensive care unit patients when compared against a reference label set based upon analysis of respiratory muscle activity. El...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-019-00442-5

    authors: Phan TS,Costa R,Haddad WM,Mullis JC,Price LT,Cason AD,Bailey JM,Gholami B

    更新日期:2020-12-01 00:00:00

  • Breathing variability predicts the suggested need for corrective intervention due to the perceived severity of patient-ventilator asynchrony during NIV.

    abstract::Patient-ventilator asynchrony is associated with intolerance to noninvasive ventilation (NIV) and worsened outcomes. Our goal was to develop a tool to determine a patient needs for  intervention by a practitioner due to the presence of patient-ventilator asynchrony. We postulated that a clinician can determine when a ...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-019-00408-7

    authors: Tams C,Stephan PJ,Euliano NR,Martin AD,Patel R,Ataya A,Gabrielli A

    更新日期:2020-10-01 00:00:00

  • The sounds of saturation.

    abstract::Audible pulse tones, based on a variable-pitch frequency scale, allow the anesthesiologist to determine the patient's oxygen saturation without constant visual examination of the monitor display. The ability to reliably detect oxygen saturation levels based on audible pulse tones may be compromised when multiple pulse...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1023/b:jocm.0000032698.47717.06

    authors: Santamore DC,Cleaver TG

    更新日期:2004-04-01 00:00:00

  • Simulating physiological interactions in a hybrid system of mathematical models.

    abstract::Mathematical models can be deployed to simulate physiological processes of the human organism. Exploiting these simulations, reactions of a patient to changes in the therapy regime can be predicted. Based on these predictions, medical decision support systems (MDSS) can help in optimizing medical therapy. An MDSS desi...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-013-9502-1

    authors: Kretschmer J,Haunsberger T,Drost E,Koch E,Möller K

    更新日期:2014-12-01 00:00:00

  • A new calibration method that compensates for the effects of O2 and N2 on infrared CO2 analysers.

    abstract:OBJECTIVE:This study evaluates a method for calibrating mainstream CO(2) analysers in which CO(2) partial pressure (P (CO2)) is calculated as a function of the outputs of CO(2) and O(2) analysers. METHODS:Three mass flow controllers were used to generate 25 different reference mixtures of O(2), N(2) and CO(2). Referen...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-005-9005-9

    authors: Tang Y,Turner MJ,Baker AB

    更新日期:2006-04-01 00:00:00

  • Endotracheal tube inflation tubing defect: an unusual cause of intraoperative volume leak.

    abstract::Loss of endotracheal cuff pressure can lead to airway compromise and loss of volume delivery in mechanical ventilation requiring immediate intervention. A 40 years old male posted for bilateral interpositional arthroplasty was intubated nasally with 7.5 mm flexometallic endotracheal tube. In the intraoperative period ...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 信件

    doi:10.1007/s10877-020-00607-7

    authors: Kumar A,Kumar A,Kumar N,Kumar A

    更新日期:2020-10-23 00:00:00

  • Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predicted tolerance to laryngoscopy of 90.

    abstract::This prospective study evaluates haemodynamic and electroencephalographic effects observed when administering four combinations of effect-site concentrations of propofol (CePROP) and remifentanil (CeREMI), all yielding a single predicted probability of tolerance of laryngoscopy of 90% (PTOL = 90%) according to the Bou...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-020-00540-9

    authors: van den Berg JP,Absalom AR,Venema AM,Kalmar AF,Van Amsterdam K,Hannivoort LN,Proost JH,Meier S,Scheeren TWL,Struys MMRF,Vereecke HEM

    更新日期:2020-06-03 00:00:00

  • Functional residual capacity measurement during tracheal gas insufflation.

    abstract:OBJECTIVE:Tracheal gas insufflation (TGI) is considered an adjunctive method to enhance carbon dioxide elimination during permissive hypercapnia in patients with acute respiratory distress syndrome. Due to increasing tidal volume and/or expiratory resistance, TGI may cause intrinsic PEEP (PEEPi), and may lessen the adv...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1023/a:1009998100819

    authors: Fujino Y,Nishimura M,Hirao O,Taenaka N,Yoshiya I

    更新日期:1998-05-01 00:00:00

  • Evaluating the efficiency of desflurane reflection in two commercially available reflectors.

    abstract::With the AnaConDa™ and the MIRUS™ system, volatile anesthetics can be administered for inhalation sedation in intensive care units. Instead of a circle system, both devices use anesthetic reflectors to save on the anesthetic agent. We studied the efficiency of desflurane reflection with both devices using different ti...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-016-9902-0

    authors: Bomberg H,Wessendorf M,Bellgardt M,Veddeler M,Wagenpfeil S,Volk T,Groesdonk HV,Meiser A

    更新日期:2018-08-01 00:00:00

  • Teaching respiratory physiology: clinical correlation with a human patient simulator.

    abstract::In recent years students have increasingly objected to laboratory exercises involving animal subjects. We have replaced the valuable animal experiments with demonstrations using a full-scale human patient simulator. In small groups first-year medical students observe realistic clinical situations such as opioid-induce...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1023/a:1011401011887

    authors: Euliano TY

    更新日期:2000-01-01 00:00:00

  • Generic and patient-specific models of the arterial tree.

    abstract::Recent advance in imaging modalities used frequently in clinical routine can provide description of the geometrical and hemodynamical properties of the arterial tree in great detail. The combination of such information with models of blood flow of the arterial tree can provide further information, such as details in p...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章,评审

    doi:10.1007/s10877-012-9382-9

    authors: Reymond P,Vardoulis O,Stergiopulos N

    更新日期:2012-10-01 00:00:00

  • Lessons learned from closed loops in engineering: towards a multivariable approach regulating depth of anaesthesia.

    abstract::In this paper is presented a brief state of art regarding the multivariable formulation for controlling the depth of anaesthesia by means of two intravenously administrated drugs, i.e. propofol and remifentanil. In a feasibility study of determining a suitable variable to quantify analgesia levels in patients undergoi...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-013-9535-5

    authors: Ionescu CM,Nascu I,De Keyser R

    更新日期:2014-12-01 00:00:00

  • Risk factors for positioning-related somatosensory evoked potential changes in 3946 spinal surgeries.

    abstract::The goal of this study was to evaluate the risk factors associated with positioning-related SSEP changes (PRSC). The study investigated the association between 18 plausible risk factors and the occurrence of intraoperative PRSC. Risk factors investigated included demographic variables, comorbidities, and procedure rel...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-018-0148-x

    authors: Melachuri SR,Balzer JR,Melachuri MK,Ninaci D,Anetakis K,Kaur J,Crammond DJ,Thirumala PD

    更新日期:2019-04-01 00:00:00

  • Closed-loop regulation of arterial pressure after acute brain death.

    abstract::The purpose of this concept study was to investigate the possibility of automatic mean arterial pressure (MAP) regulation in a porcine heart-beating brain death (BD) model. Hemodynamic stability of BD donors is necessary for maintaining acceptable quality of donated organs for transplantation. Manual stabilization is ...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-017-0033-z

    authors: Soltesz K,Sjöberg T,Jansson T,Johansson R,Robertsson A,Paskevicius A,Liao Q,Qin G,Steen S

    更新日期:2018-06-01 00:00:00

  • Design and α-testing of an electronic rounding tool (CERTAINp) to improve process of care in pediatric intensive care unit.

    abstract::Increasing process complexity in the pediatric intensive care unit (PICU) can lead to information overload resulting in missing pertinent information and potential errors during morning rounds. An efficient model using a novel electronic rounding tool was designed as part of a broader critical care decision support sy...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-016-9946-1

    authors: Hulyalkar M,Gleich SJ,Kashyap R,Barwise A,Kaur H,Dong Y,Fan L,Murthy S,Arteaga GM,Tripathi S

    更新日期:2017-12-01 00:00:00

  • The units of measurement of the ventricular stroke work: a review study.

    abstract:BACKGROUND:The ventricular stroke work refers to the work done by the left or right ventricle to eject the volume of blood during one cardiac cycle, called stroke volume. Sarnoff and Berglund were one of the first to calculate the stroke work from the pressure volume diagram in 1954. However, they published a wrong uni...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章,评审

    doi:10.1007/s10877-010-9234-4

    authors: Schramm W

    更新日期:2010-06-01 00:00:00

  • Detection of intratracheal accumulation of thick secretions by using continuous monitoring of respiratory acoustic spectrum: a preliminary analysis.

    abstract::The accumulation of tracheobronchial secretions may contribute to a deterioration in pulmonary function and its early detection is important. In this study, we analyzed the respiratory sound spectrum in patients with intratracheal secretion, and compared acoustic characteristics before and after therapeutic endotrache...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-019-00359-z

    authors: Moon YJ,Bechtel AJ,Kim SH,Kim JW,Thiele RH,Blank RS

    更新日期:2020-08-01 00:00:00

  • EEG sources of noise in intraoperative somatosensory evoked potential monitoring during propofol anesthesia.

    abstract:OBJECTIVE:It was hypothesized that somato- sensory evoked potentials can be achieved faster by selective averaging during periods of low spontaneous electroen- cephalographic (EEG) activity. We analyzed the components of EEG that decrease the signal-to-noise ratio of somatosensory evoked potential (SEP) recordings duri...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-009-9188-6

    authors: Joutsen A,Puumala P,Lyytikäinen LP,Pajulo O,Etelämäki A,Eskola H,Jäntti V

    更新日期:2009-08-01 00:00:00

  • Electrical impedance tomography's correlation to lung volume is not influenced by anthropometric parameters.

    abstract:STUDY OBJECTIVES:Electrical impedance tomography (EIT) is able to reflect physiological parameters such as real-time changes in global and regional lung volume. EIT can aid in the assessment of lung recruitment, and its use has been validated in preliminary studies monitoring mechanical ventilation at the bedside. ICU ...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-006-9021-4

    authors: Marquis F,Coulombe N,Costa R,Gagnon H,Guardo R,Skrobik Y

    更新日期:2006-06-01 00:00:00

  • Comparison of the use of AnaConDa® versus AnaConDa-S® during the post-operative period of cardiac surgery under standard conditions of practice.

    abstract::Changes have been made to the AnaConDa device (Sedana Medical, Stockholm, Sweden), decreasing its size to reduce dead space and carbon dioxide (CO2) retention. However, this also involves a decrease in the surface area of the activated carbon filter. The CO2 elimination and sevoflurane (SEV) reflection of the old devi...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-019-00285-0

    authors: Marcos-Vidal JM,Merino M,González R,García C,Rey S,Pérez I

    更新日期:2020-02-01 00:00:00

  • A simplified 4-parameter model of volumetric capnograms improves calculations of airway dead space and slope of Phase III.

    abstract::To evaluate a compact and easily interpretable 4-parameter model describing the shape of the volumetric capnogram, and the resulting estimates of anatomical dead space (VDAW) and Phase III (alveolar plateau) slope (SIII). Data from of 8 mildly-endotoxemic pre-acute respiratory distress syndrome sheep were fitted to th...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-019-00451-4

    authors: Motta-Ribeiro GC,Vidal Melo MF,Jandre FC

    更新日期:2020-12-01 00:00:00

  • Predictive data mining on monitoring data from the intensive care unit.

    abstract::The widespread implementation of computerized medical files in intensive care units (ICUs) over recent years has made available large databases of clinical data for the purpose of developing clinical prediction models. The typical intensive care unit has several information sources from which data is electronically co...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-012-9416-3

    authors: Güiza F,Van Eyck J,Meyfroidt G

    更新日期:2013-08-01 00:00:00

  • A comparison of ventricular systolic function indices provided by VolumeView/EV1000™ and left ventricular ejection fraction by echocardiography among septic shock patients.

    abstract::The aim of this study was to compare the cardiac function index (CFI) and global ejection fraction (GEF) obtained by VolumeView/EV1000™, with the left ventricular ejection fraction (LVEF) by echocardiography in septic shock patients. A prospective observational study was conducted in a medical intensive care unit of a...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-018-0152-1

    authors: Nakwan N,Chichareon P,Khwannimit B

    更新日期:2019-04-01 00:00:00

  • The comparison of the technical parameters in endotracheal intubation devices: the Cmac, the Vividtrac, the McGrath Mac and the Kingvision.

    abstract::Currently, there are plenty of videolaryngoscopes that appear on the market. They have different specifications. Some of these features favor the fact that they are more suited for educational purposes of future operators and others can be characterized with an excellent clinical use. In this study we compared four ty...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1007/s10877-015-9727-2

    authors: Cierniak M,Timler D,Wieczorek A,Sekalski P,Borkowska N,Gaszynski T

    更新日期:2016-08-01 00:00:00

  • Transcranial Doppler monitoring compared with invasive monitoring of intracranial pressure during acute intracranial hypertension.

    abstract:OBJECTIVE:To determine whether a simple transcanial Doppler waveform variable-pulsatility difference (systolic - diastolic blood flow velocity) can serve as a measure of critical changes in cerebral perfusion. METHODS:Thirteen pigs were anesthetized (anesthesia maintained with halothane) and ventilated to maintain nor...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1023/a:1009993232534

    authors: Sidi A,Messinger G,Mahla ME

    更新日期:1999-05-01 00:00:00

  • BAEPs averaging analysis using autoregressive modelling.

    abstract:OBJECTIVE:The present paper introduces a new perspective on the classical ensemble averaging which can be useful to analyse the Brainstem Auditory Evoked Potentials (BAEPs). The analysis of the dynamics, related to the BAEP, is performed directly after its acquisition from the electroencephalogram (EEG). METHODS:The m...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 杂志文章

    doi:10.1023/b:jocm.0000042919.04719.a7

    authors: Vannier E,Naït-Ali A

    更新日期:2004-06-01 00:00:00

  • Unconsciousness indication using time-domain parameters extracted from mid-latency auditory evoked potentials.

    abstract:OBJECTIVE:The mid-latency auditory evoked potential (MLAEP) has been used to indicate depth of anaesthesia, and is usually analysed in time-domain. This work compares three techniques: Wave Deformation Parameters (PDO), Auditory Evoked Potential Index (AEPidx) and an automatic Nb-wave latency estimator (Nb), in the ass...

    journal_title:Journal of clinical monitoring and computing

    pub_type: 临床试验,杂志文章

    doi:10.1023/a:1024208827407

    authors: Cagy M,Infantosi AF

    更新日期:2002-08-01 00:00:00