European clinical evaluation: use of Intacs for the treatment of keratoconus.


PURPOSE:To evaluate the safety and efficacy of Intacs inserts in keratoconic eyes to alter corneal shape and refractive power and stabilize the progression of corneal ectasia. SETTING:Service d'Ophtalmologie, Bordeaux, France. METHODS:In this prospective study, 57 eyes with clear central corneas that were diagnosed with keratoconus and contact lens intolerant were followed for up to 1 year. The primary objectives were to assess the safety of Intacs and the visual outcomes by measuring uncorrected visual acuity (UCVA), best corrected visual acuity, manifest refraction spherical equivalent, keratometry, intraocular pressure (IOP), pachymetry, and patient satisfaction. The stability of the refraction, keratometry, and visual acuity measurements was also assessed. RESULTS:At the 6-month examination, 78% of patients showed improvement of 2 lines or more in UCVA (P<.001). Best corrected visual acuity of 20/40 or better improved from 53% of patients preoperatively to 74% of patients (P< or =.033). Manifest refraction spherical equivalent improved to 3.1 +/- 2.5 diopters (D) (P<.001) compared with the preoperative examination. Keratometry decreased a mean of -4.3 +/- 2.8 D from the preoperative readings (P< or =.002). These changes appeared to be stable over time. At 6 months, there were no adverse events, no clinically significant increase in IOP, and no decrease in central corneal thickness. In 7 of 57 eyes (12%), the Intacs were removed due to dissatisfaction with visual symptoms. There were no adverse effects or complications associated with the Intacs removal. CONCLUSIONS:Intacs were safe and effective for treating keratoconus. All patients demonstrated improved objective visual outcomes; functional vision was restored in most patients. Intacs were removed without permanent sequelae.


Colin J




Has Abstract


2006-05-01 00:00:00














  • Capsulorhexis contraction after cataract surgery: comparison of sharp anterior edge and modified anterior edge acrylic intraocular lenses.

    abstract:PURPOSE:To evaluate the reduction in the anterior capsule opening after phacoemulsification, continuous curvilinear capsulorhexis, and implantation of 1 of 2 acrylic intraocular lenses (IOLs). SETTING:Department of Ophthalmology, Vejle Hospital, Vejle, Denmark. METHODS:Eighty-four patients (84 eyes) were included in ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章,随机对照试验


    authors: Corydon C,Lindholt M,Knudsen EB,Graakjaer J,Corydon TJ,Dam-Johansen M

    更新日期:2007-05-01 00:00:00

  • Smoothness assessment of corneal stromal surfaces.

    abstract:PURPOSE:To assess the accuracy of the scanning electron microscopy (SEM) and present alternative approaches to quantify surface roughness based on numerical analysis. SETTING:Department of Ophthalmology, Maisonneuve-Rosemont Hospital, University of Montreal, Montreal, Quebec, Canada. DESIGN:Experimental study. METHO...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Marian A,Nada O,Légaré F,Meunier J,Vidal F,Roy S,Brunette I,Costantino S

    更新日期:2013-01-01 00:00:00

  • Alteration of free radical development by ophthalmic viscosurgical devices in phacoemulsification.

    abstract:PURPOSE:To determine the effect of ophthalmic viscosurgical devices (OVDs) and irrigation/aspiration (I/A) settings on free radical development during phacoemulsification. SETTING:Department of Ophthalmology, Nippon Medical School, Tokyo, Japan. METHODS:Free radicals were detected by the electron spin resonance (ESR)...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Takahashi H,Suzuki H,Shiwa T,Sakamoto A

    更新日期:2006-09-01 00:00:00

  • Single versus double femtosecond laser pass for incomplete laser in situ keratomileusis flap in contralateral eyes: visual and optical outcomes.

    abstract:PURPOSE:To evaluate visual acuity, refractive outcomes, and anterior corneal higher-order aberrations (HOAs) after myopic laser in situ keratomileusis (LASIK) with uneventful single femtosecond laser pass versus double pass performed for intraoperative suction loss. SETTING:Private refractive surgery center, Valencia,...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Muñoz G,Albarrán-Diego C,Ferrer-Blasco T,Javaloy J,García-Lázaro S

    更新日期:2012-01-01 00:00:00

  • Price graft-over-host technique to manage positive pressure during penetrating keratoplasty.

    abstract::Intraoperative positive pressure with resulting iris and lens prolapse can pose a difficult scenario during penetrating keratoplasty. In the Price graft-over-host technique, the graft is sutured across the trephinated host cornea, which maintains a formed anterior chamber and thus avoids intraoperative complications. ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Loden JC,Price FW Jr

    更新日期:1998-06-01 00:00:00

  • Excimer laser photorefractive keratectomy for high myopia.

    abstract::One hundred and thirty-three eyes of 103 patients had photorefractive keratectomy with a slit scan mode excimer laser for myopia ranging from -6.00 to -22.00 diopters (D). The epithelium was removed with 20% ethanol, and the ablation was done with a tapered profile surrounding the optical zone. Patients were divided i...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Menezo JL,Martinez-Costa R,Navea A,Roig V,Cisneros A

    更新日期:1995-07-01 00:00:00

  • Repeatability and reliability of ectasia display and topometric indices with the Scheimpflug system in normal and keratoconic eyes.

    abstract:PURPOSE:To evaluate the repeatability and reliability of Belin-Ambrósio Enhanced Ectasia Display-III indices and topometric indices with a Scheimpflug system (Pentacam HR) in normal eyes and keratoconic eyes. SETTING:Ulucanlar Eye Research and Training Hospital, Ankara, Turkey. DESIGN:Prospective case series. METHOD...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Kosekahya P,Koc M,Caglayan M,Kiziltoprak H,Atilgan CU,Yilmazbas P

    更新日期:2018-01-01 00:00:00

  • Cell adhesion on explanted intraocular lenses: part 1: analysis of explanted IOLs.

    abstract:PURPOSE:To determine whether cell adhesion on an intraocular lens (IOL) in Japanese patients is affected by the optic material. SETTING:Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan. DESIGN:Experimental study. METHODS:Intraocular lenses of various materials explanted from Japanese patient...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Ishikawa N,Miyamoto T,Okada Y,Saika S

    更新日期:2011-07-01 00:00:00

  • Comparison of the effect of AquaLase and NeoSoniX phacoemulsification on the corneal endothelium.

    abstract:PURPOSE:To compare the extent of corneal endothelial cell loss and pachymetry changes in 2 age-based groups of patients who had cataract removal by AquaLase (Alcon) phacoemulsification in 1 eye and NeoSoniX (Alcon) phacoemulsification in the contralateral eye. SETTING:Department of Ophthalmology, University Hospital, ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Jirásková N,Kadlecová J,Rozsíval P,Nekolová J,Pozlerova J,Dúbravská Z

    更新日期:2008-03-01 00:00:00

  • Acute endophthalmitis outbreak after cataract surgery.

    abstract:PURPOSE:To evaluate the source of organisms causing an epidemic of postoperative endophthalmitis and to emphasize the importance of prompt intervention with an early diagnosis. SETTING:S.B. Ankara Hospital Eye Department, Ankara, Turkey. METHODS:Thirteen patients who had surgery on the same day and developed acute po...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Arsan AK,Adişen A,Duman S,Aslan B,Koçak I

    更新日期:1996-10-01 00:00:00

  • Surgical technique for small-incision intraocular lens exchange.

    abstract::We present a simple, effective technique to remove an intraocular lens (IOL) via a very small incision (2.2 mm). After the IOL is carefully removed from the capsular bag, into the anterior chamber, 2 radial incisions, 35 degrees to 50 degrees apart, are made with a Vannas scissors. This results in 2 IOL pieces (maximu...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Karamaounas N,Kourkoutas D,Prekates C

    更新日期:2009-07-01 00:00:00

  • Evaluation of variables affecting intraoperative aberrometry.

    abstract:PURPOSE:To understand some of the variable refractive changes that occur during routine cataract surgery that could affect the accuracy and effectiveness of intraoperative aberrometry as it relates to the postoperative refractive state. SETTING:John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Stringham J,Pettey J,Olson RJ

    更新日期:2012-03-01 00:00:00

  • Contrast sensitivity and glare in patients with a diffractive multifocal intraocular lens.

    abstract::Contrast sensitivity was measured in 25 patients who had a multifocal diffractive intraocular lens and in 23 control patients with a monofocal lens in four simulated light conditions: (1) daylight, (2) daylight with peripheral glare, (3) twilight, (4) twilight with central glare. In normal daylight and twilight, contr...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Winther-Nielsen A,Corydon L,Olsen T

    更新日期:1993-03-01 00:00:00

  • Expanding depth of focus by modifying higher-order aberrations induced by an adaptive optics visual simulator.

    abstract:PURPOSE:To evaluate the impact of higher-order aberrations on depth of focus using an adaptive optics visual simulator. SETTING:Refractive Surgery Department, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA. METHODS:An adaptive optics simulator was used to optically introduce individual aberrations in eyes...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Rocha KM,Vabre L,Chateau N,Krueger RR

    更新日期:2009-11-01 00:00:00

  • Implantation of an Artisan iris-fixated phakic intraocular lens for the correction of hyperopia, a 15 year follow-up.

    abstract:PURPOSE:To assess the predictability, efficacy, stability and safety of implantation of an Artisan (Ophtec BV, the Netherlands) iris-fixated phakic intraocular lens (IF-pIOL) for the correction of hyperopia with a follow-up of up to 15 years. SETTING:Leiden University Medical Center, The Netherlands METHODS:: Patients...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: van Rijn GA,Gaurisankar ZS,Saxena R,Gibbes D,Jongman HP,Haasnoot GW,Cheng YYY,Beenakker JM,Luyten GPM

    更新日期:2020-11-27 00:00:00

  • Phacoemulsification in spherophakia with corneal touch.

    abstract::A phacoemulsification procedure with implantation of a foldable acrylic intraocular lens in a 31-year-old man with spherophakia is described. The procedure was necessitated by anterior dislocation of the spherophakic lens, with corneal endothelial contact and development of central corneal edema. With a careful approa...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Behndig A

    更新日期:2002-01-01 00:00:00

  • Effect of genipin collagen crosslinking on porcine corneas.

    abstract:PURPOSE:To evaluate the effect of genipin, a natural crosslinker, on porcine corneas. SETTING:Department of Ophthalmology, Universidad Nacional de Colombia, Bogota, Colombia. METHODS:Corneal strips (12.0 mm x 2.3 mm) were harvested from porcine eyes and treated by incubation with genipin at concentrations of 1.00%, 0...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Avila MY,Navia JL

    更新日期:2010-04-01 00:00:00

  • Modified posterior-assisted levitation with intraocular lens scaffold and glued IOL for sinking nucleus in eyes with inadequate sulcus support.

    abstract::Posterior-assisted levitation is used to retrieve and levitate a sinking nucleus in cataract surgery associated with posterior capsule rupture. After the nucleus is levitated in the anterior chamber, the intraocular lens (IOL) scaffold procedure helps emulsify the nuclear remnants with the phacoemulsification probe an...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Narang P,Agarwal A

    更新日期:2017-07-01 00:00:00

  • Unwanted optical images with narrow profile intraocular lenses compared with conventional intraocular lenses.

    abstract::About 35% of intraocular lenses now implanted in the United States are narrow profile lenses, measuring on the average 5.0 mm by 6.0 mm. This study sought to determine whether these lenses cause unwanted optical images with a decrease in the quality of vision. Seventy-five eyes with a 5.0 mm x 6.0 mm intraocular lens ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Armstrong TA

    更新日期:1993-09-01 00:00:00

  • Complications of pediatric cataract surgery and intraocular lens implantation.

    abstract:PURPOSE:To study the pattern of postoperative complications following extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation in pediatric eyes. SETTING:Tertiary eye care center, New Delhi, India. METHODS:A retrospective analysis of 39 eyes of 28 children referred for complications after ECC...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Sharma N,Pushker N,Dada T,Vajpayee RB,Dada VK

    更新日期:1999-12-01 00:00:00

  • Myopic keratomileusis: results with a follow-up over one year.

    abstract::We report one-year follow-up results on 23 eyes in which we performed myopic keratomileusis. The mean refraction changed from -11.09 diopters (D) preoperatively to -3.66 D postoperatively. In all but two cases, keratometry was reduced one year postoperatively. The average corneal thickness decrease was 0.139 mm. In ni...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Dossi F,Bosio P

    更新日期:1987-07-01 00:00:00

  • Femtosecond laser-assisted hyperopic laser in situ keratomileusis with tissue-saving ablation: analysis of 800 eyes.

    abstract:PURPOSE:To evaluate the results and complications of hyperopic laser in situ keratomileusis (LASIK) with a low-energy femtosecond laser and non-custom tissue-saving ablation profile. SETTING:Private practice, Siena, Italy. DESIGN:Case series. METHODS:Hyperopic eyes with a spherical equivalent (SE) between +1.0 and +...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Leccisotti A

    更新日期:2014-07-01 00:00:00

  • Astigmatically neutral sutured small incision.

    abstract::The desire for rapid visual rehabilitation following phacoemulsification for cataract and intraocular lens implantation has stimulated a quest for an "astigmatically neutral" incision. We have evaluated an underemphasized aspect of wound closure technique for a small incision wound (5.1 mm). The essential element of t...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Pacifico RL,Morrison C

    更新日期:1991-01-01 00:00:00

  • Thin flap laser in situ keratomileusis: flap dimensions with the Moria LSK-One manual microkeratome using the 100-microm head.

    abstract:PURPOSE:To determine the predictability and consistency of corneal flap thickness, flap diameter, and hinge length with the modern 100 microm head of the Moria LSK-One manual microkeratome. SETTING:Private clinic, office-based practice. METHODS:Forty-two consecutive eyes with no previous surgery having thin flap lase...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Duffey RJ

    更新日期:2005-06-01 00:00:00

  • Corneal chromoblastomycosis caused by Cladophialophora carrionii after cataract surgery.

    abstract::We describe a case of corneal chromoblastomycosis with Cladophialophora carrionii in a 69-year-old woman 4 weeks after clear corneal cataract surgery. The patient presented with right eye pain and decreased visual acuity of 20/100. Examination showed a deep posterior stromal keratitis accompanied by a dense fibrinous ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Lari HB,Mirani N,Chu DS

    更新日期:2011-05-01 00:00:00

  • Single perioperative triamcinolone injection versus standard postoperative steroid drops after uneventful phacoemulsification surgery: Randomized controlled trial.

    abstract:PURPOSE:To evaluate the safety and efficacy of a single perioperative sub-Tenon's injection of triamcinolone following cataract surgery and its effect on the incidence of early pseudophakic cystoid macular edema (CME). SETTING:Ophthalmology Department, Queen's Medical Centre University Hospital, Nottingham. United Kin...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章,随机对照试验


    authors: Negi AK,Browning AC,Vernon SA

    更新日期:2006-03-01 00:00:00

  • Early bacterial keratitis after laser-assisted subepithelial keratectomy.

    abstract::We report a case of bacterial keratitis that occurred after laser-assisted subepithelial keratectomy. The patient presented with a decrease in visual acuity and pain 2 days after the procedure. Culture was positive for Staphylococcus haemolyticus. The infiltrate slowly resolved with topical antibiotics, and the best c...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Laplace O,Bourcier T,Chaumeil C,Cardine S,Nordmann JP

    更新日期:2004-12-01 00:00:00

  • Visual quality after monovision correction by laser in situ keratomileusis in presbyopic patients.

    abstract:PURPOSE:To evaluate visual quality after laser in situ keratomileusis (LASIK) performed to achieve monovision in presbyopic patients. SETTING:Laboratory of Vision Sciences and Applications, Department of Optics, University of Granada, Granada, and Clínica Novovisión, Madrid, Spain. DESIGN:Cohort study. METHODS:Laser...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Alarcón A,Anera RG,Villa C,Jiménez del Barco L,Gutierrez R

    更新日期:2011-09-01 00:00:00

  • Successful management of epithelial ingrowth after sequential intracameral 5-fluorouracil and Descemet-stripping automated endothelial keratoplasty.

    abstract::To describe the successful treatment of epithelial ingrowth using combined surgical excision with intracameral adjuvant 5-fluorouracil (5-FU) followed by Descemet-stripping automated endothelial keratoplasty (DSAEK). A 71-year-old man presented with epithelial ingrowth after clear corneal phacoemulsification. He under...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章


    authors: Koenig SB,Koenig LR,Connor TB,Simons KB

    更新日期:2019-05-01 00:00:00

  • Attaining the optimal flange for intrascleral intraocular lens fixation.

    abstract::We describe a technique for making an optimal flange in intraocular lenses (IOLs) used for flanged intrascleral IOL fixation. The flange shape varies in poly(methyl methacrylate) (PMMA) haptics of different IOLs of different manufacturers. We identified the distance between the forceps grip of the haptic and the end o...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 评论,杂志文章


    authors: Kronschläger M,Blouin S,Roschger P,Varsits R,Findl O

    更新日期:2018-11-01 00:00:00