Immediate injection pain in infants aged 18 months during vaccination against measles, mumps and rubella with either Priorix or MMR-II.

Abstract:

:The aim of this study was to investigate whether, the vaccine Priorix causes less immediate injection pain than MMR-II in vaccination of infants aged 18-24 months who were offered vaccine against measles, mumps and rubella. The infants were randomised into one of the two vaccine groups (Priorix/MMR-II in a double-blind study. One observer assessed pain, using CHEOPS (Children's Hospital Eastern Ontario Pain scale), and the parent used the Visual Analogue Pain scale (VAS). Pain assessment was made in 295 infants. Mean age was 19.08 months. Mean VAS value was 2.3/5.2 for Priorix and MMR-II, respectively (p<0.001). Mean CHEOPS value was 1.9/6.1 for Priorix and MMR-II, respectively (p<0.001). The study shows that Priorix gives less immediate injection pain than MMR-II.

journal_name

Vaccine

journal_title

Vaccine

authors

Knutsson N,Jansson UB,Alm B

doi

10.1016/j.vaccine.2006.05.004

subject

Has Abstract

pub_date

2006-07-26 00:00:00

pages

5800-5

issue

31-32

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(06)00540-8

journal_volume

24

pub_type

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