Abstract：
:The aim of this study was to investigate whether, the vaccine Priorix causes less immediate injection pain than MMR-II in vaccination of infants aged 18-24 months who were offered vaccine against measles, mumps and rubella. The infants were randomised into one of the two vaccine groups (Priorix/MMR-II in a double-blind study. One observer assessed pain, using CHEOPS (Children's Hospital Eastern Ontario Pain scale), and the parent used the Visual Analogue Pain scale (VAS). Pain assessment was made in 295 infants. Mean age was 19.08 months. Mean VAS value was 2.3/5.2 for Priorix and MMR-II, respectively (p<0.001). Mean CHEOPS value was 1.9/6.1 for Priorix and MMR-II, respectively (p<0.001). The study shows that Priorix gives less immediate injection pain than MMR-II.
journal_name
Vaccinejournal_title
Vaccineauthors
Knutsson N,Jansson UB,Alm Bdoi
10.1016/j.vaccine.2006.05.004subject
Has Abstractpub_date
2006-07-26 00:00:00pages
5800-5issue
31-32eissn
0264-410Xissn
1873-2518pii
S0264-410X(06)00540-8journal_volume
24pub_type
杂志文章,随机对照试验相关文献
VACCINE文献大全abstract：:In 2013, avian H7N9 influenza viruses were detected infecting people in China resulting in high mortality. Influenza H7 vaccines that provide cross-protection against these new viruses are needed until specific H7N9 vaccines are ready to market. In this study, an available H7N3 cold-adapted, temperature sensitive, liv...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2014.11.008
更新日期：2015-01-01 00:00:00
abstract：:Increasing mortality, morbidity and economic costs have been paid to pneumococcal diseases every year. Currently, vaccination is the most promising strategy to reduce the occurrence of pneumococcal infection. In this study, we investigated the protective efficacy of immunization with recombinant DnaJ (hsp40) protein a...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.12.126
更新日期：2011-02-17 00:00:00
abstract：:Genetic immunization holds promise as a vaccination method, but has so far proven ineffective in large primate and human trials. Herein, we examined the relative merits of genetic immunization and peptide immunization using bacteriophage λ. Bacteriophage λ has proven effective in immune challenge models using both imm...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2011.12.070
更新日期：2012-02-01 00:00:00
abstract：:Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further explored options to...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2019.10.040
更新日期：2020-01-10 00:00:00
abstract：:We determined the immunogenicity of conjugated Haemophilus influenzae type b and pneumococcal vaccines by quantitative analysis of the antibody response in asplenic patients. To that end, we vaccinated 92 patients with a conjugated Hib vaccine and 54 received two doses of conjugated pneumococcal vaccine (PCV7), follow...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.11.034
更新日期：2011-01-17 00:00:00
abstract：:A recombinant Lactobacillus casei expressing a flagellar antigen from Salmonella enterica serovar Enteritidis was constructed and evaluated as a mucosal vaccine. Intragastric immunization of the recombinant strain conferred protective immunity against Salmonella infection in mice. This immunization did not result in a...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2007.01.055
更新日期：2007-05-04 00:00:00
abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2005.09.034
更新日期：2006-02-27 00:00:00
abstract：:The paper presents the first results from the European project VACSATC which aimed to track parental attitudes on vaccinations across several European countries. We compared five cross-sectional surveys of parents with children less than 3 years of age in England, Norway, Poland, Spain and Sweden carried out during 20...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.06.009
更新日期：2010-08-09 00:00:00
abstract：:A safe and effective pan-filovirus vaccine is highly desirable since the filoviruses Ebola virus (EBOV) and Marburg virus (MARV) cause highly lethal disease typified by unimpeded viral replication and severe hemorrhagic fever. Previously, we showed that expression of the homologous glycoprotein (GP) and matrix protein...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.11.070
更新日期：2005-04-27 00:00:00
abstract：:Studies conducted at neonatal intensive care units in Pune, western India, suggested early exposure to rotaviruses and predominance of unusual human-bovine-like G12P[11] strains. The whole genome sequencing and phylogenetic analyses of a naturally attenuated, culture adapted neonatal strain, (NIV-1740121) revealed mul...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.01.081
更新日期：2020-02-28 00:00:00
abstract：:We successfully re-vaccinated hepatitis B virus (HBV) vaccine non-responders using a double dose of the combined hepatitis A virus (HAV) and HBV vaccine. The hope was to improve priming of hepatitis B surface antigen (HBsAg)-specific cell mediated immune response (CMI) by an increased antigen dose and a theoretical ad...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2008.08.054
更新日期：2008-11-05 00:00:00
abstract：:HPV vaccines are highly immunogenic. A two-dose schedule for 9-14 year-old is recommended. However, no data exist regarding the impact of age, menarche status and body mass index (BMI) on the immune response to a two-dose schedule. In this post-hoc analysis, we present antibody titers to HPV6/11/16/18 in 9-13 year-old...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2019.09.089
更新日期：2019-11-20 00:00:00
abstract：:The presence of resident Langerhans cells (LCs) in the epidermis makes the skin an attractive target for DNA vaccination. However, reliable animal models for cutaneous vaccination studies are limited. We demonstrate an ex vivo human skin model for cutaneous DNA vaccination which can potentially bridge the gap between ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.07.088
更新日期：2009-10-09 00:00:00
abstract：:Dengue disease is a global challenge for healthcare systems particularly during outbreaks, and millions of dollars are spent every year for vector control. An efficient and safe vaccine that is cost-effective could resolve the burden that dengue virus imposes on affected countries. We describe here the immunogenicity ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2015.01.074
更新日期：2015-03-17 00:00:00
abstract：:Streptococcus pneumoniae is one of the leading bacterial pathogens causing invasive disease and non-invasive infections at both extremes of life: in children younger than 5 years and in elderly persons of 65 years or more. Pneumococcal infections result in substantial morbidity and mortality among children under 5 yea...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2011.06.104
更新日期：2011-09-14 00:00:00
abstract：:Fifty injecting drug users (IDUs) were recruited to evaluate the efficacy of an hepatitis B virus (HBV) vaccination campaign to be carried out in a Public centre for Drug Users (PCDU). The vaccination schedule was successfully performed in most patients, who showed a great interest in this problem. After three doses o...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(96)00290-3
更新日期：1997-06-01 00:00:00
abstract：:Serum specimens of 1075 young adults representing nursing and medical staff were collected for determination of rubella immunity using the radial haemolysis (RH) technique, also know as the haemolysis in gel (HIG) test. Of the sera 84 (7.8%) were negative (RH titre less than 4 mm) and an additional 93 (8.7%) gave an R...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(86)90090-3
更新日期：1986-03-01 00:00:00
abstract：:A varicella-zoster virus (VZV) seropositive individual was immunized with 100 micrograms of purified VZV TgpI-511 glycoprotein subunit antigen formulated with monophosphoryl lipid A. Serum samples were obtained during a 40-day period post-immunization (PI) and analysed by immunoprecipitation and virus neutralization t...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(94)00073-v
更新日期：1995-10-01 00:00:00
abstract：:Patterns of microRNA expression appear to delineate the process of spontaneous neoplastic development-transformation (SPNDT) occurring in the African green monkey kidney (AGMK) VERO cell line (Teferedegne et al., 2010). Analysis of microarray data identified 6 microRNAs whose high-level of expression peaked when the W...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2017.04.004
更新日期：2017-10-04 00:00:00
abstract：:During the 2000/2001 influenza season in Japan, children ranging in age from 6 months to 13 years with fever exceeding 37.5 degrees C were recruited. Vaccine efficacy was evaluated by comparing the rates of pre-seasonal vaccination between groups stratified by fever severity. Seven hundred and sixty one patients (33.1...
journal_title：Vaccine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.vaccine.2006.01.067
更新日期：2006-04-24 00:00:00
abstract：PURPOSE:The aims of this study are to evaluate the impact of a novel immunization curriculum based on the Preferred Cognitive Styles and Decision Making Model (PCSDM) on internal medicine (IM) resident continuity clinic patient panel immunization rates, as well as resident immunization knowledge, attitudes, and practic...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2018.02.082
更新日期：2018-03-27 00:00:00
abstract：INTRODUCTION:Hepatitis B is a major preventable cause of morbidity and mortality from chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. We aimed to evaluate the performance and outcomes of the Korean Perinatal Hepatitis B Prevention Programme (PHBPP) and to investigate the impact of the current post-exp...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.05.044
更新日期：2020-07-22 00:00:00
abstract：:The vaccination program in Zambia includes one dose of measles vaccine at 9 months of age. The objective of this study was to compare the cost-effectiveness of the current one-dose measles vaccination program with an immunization schedule in which a second dose is provided either through routine health services or thr...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2003.07.007
更新日期：2004-01-02 00:00:00
abstract：:The effects on the immunity in cattle of dosage and storage of oil-based inactivated vaccine incorporating the Gladysdale strain were examined. Storage at 4 degrees C for 12 or 24 months was found not to have any marked effect on the immunity conferred in the vaccinated cattle. A dosage of 0.5 ml was found to be as ef...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(86)90142-8
更新日期：1986-12-01 00:00:00
abstract：:The apical membrane antigen 1 (AMA1) of malaria parasites is a leading vaccine candidate. Its expression in merozoites and sporozoites and its importance for erythrocyte and hepatocyte invasion underline the significance of both humoral and cellular immunities against this antigen in malaria protection. We have genera...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.05.099
更新日期：2006-09-11 00:00:00
abstract：:Over the last ten years, Chikungunya virus (CHIKV), an Old World alphavirus has caused numerous outbreaks in Asian and European countries and the Americas, making it an emerging pathogen of great global health importance. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, on the other hand, has been ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2017.05.016
更新日期：2017-06-22 00:00:00
abstract：:A new rabies vaccine was developed from Vero cells adhered to microcarriers, cultivated in a bioreactor in serum-free medium and infected with the PV/VERO-Paris rabies virus strain. The viral suspensions were concentrated by tangential filtration, purified by chromatography and inactivated with beta-propiolactone. In ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.06.014
更新日期：2004-12-09 00:00:00
abstract：:Helicobacter pylori is a Gram-negative bacterial pathogen associated with gastritis, peptic ulceration, and gastric carcinoma. The bacteria express a strong urease activity which is known to be essential for colonization of gnotobiotic pigs and nude mice. UreA and UreB, two structural subunits of the active enzyme, we...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(97)00247-8
更新日期：1998-03-01 00:00:00
abstract：:Nasal administration of vaccines is an attractive approach which offers several significant advantages over traditional intramuscular vaccine delivery. These advantages include easier administration and induction of immune responses in the mucosal secretions of the body. In this study we describe a new potent nasal ad...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(01)00156-6
更新日期：2001-07-20 00:00:00
abstract：:Recently, it was discovered that sialic acid residues on group B streptococcal (GBS) capsular polysaccharides (CPS) are O-acetylated. Since GBS vaccine development has focused on de-O-acetylated CPS, it became germane to investigate the influence of de-O-acetylated GBS vaccine formulations on functional activity of se...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.05.039
更新日期：2009-07-16 00:00:00
