Immediate injection pain in infants aged 18 months during vaccination against measles, mumps and rubella with either Priorix or MMR-II.


:The aim of this study was to investigate whether, the vaccine Priorix causes less immediate injection pain than MMR-II in vaccination of infants aged 18-24 months who were offered vaccine against measles, mumps and rubella. The infants were randomised into one of the two vaccine groups (Priorix/MMR-II in a double-blind study. One observer assessed pain, using CHEOPS (Children's Hospital Eastern Ontario Pain scale), and the parent used the Visual Analogue Pain scale (VAS). Pain assessment was made in 295 infants. Mean age was 19.08 months. Mean VAS value was 2.3/5.2 for Priorix and MMR-II, respectively (p<0.001). Mean CHEOPS value was 1.9/6.1 for Priorix and MMR-II, respectively (p<0.001). The study shows that Priorix gives less immediate injection pain than MMR-II.






Knutsson N,Jansson UB,Alm B




Has Abstract


2006-07-26 00:00:00
















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  • Do not underestimate the power of antibodies--lessons from adoptive transfer of antibodies against HIV.

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    pub_type: 杂志文章,评审


    authors: Ferrantelli F,Rasmussen RA,Hofmann-Lehmann R,Xu W,McClure HM,Ruprecht RM

    更新日期:2002-12-19 00:00:00

  • Inactivated influenza vaccine does not reduce all cause respiratory illness in children with pre-existing medical conditions.

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    authors: Boberg A,Sjöstrand D,Rollman E,Hinkula J,Zuber B,Wahren B

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  • Application of the Geographic Information System (GIS) in immunisation service delivery; its use in the 2017/2018 measles vaccination campaign in Nigeria.

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    authors: Denny L,Quinn M,Sankaranarayanan R

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  • Expression of HIV-1 envelope gene by recombinant avipox viruses.

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    authors: Radaelli A,De Giuli Morghen C

    更新日期:1994-09-01 00:00:00

  • Altered pathogenicity, immunogenicity, tissue tropism and 3'-7kb region sequence of an avian infectious bronchitis coronavirus strain after serial passage in embryos.

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    authors: Liu S,Zhang X,Gong L,Yan B,Li C,Han Z,Shao Y,Li H,Kong X

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    authors: McPheeters ML,Sathe NA,Jerome RN,Carnahan RM

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  • Meningococcal surrogates of protection--serum bactericidal antibody activity.

    abstract::Despite the availability of anti-microbial agents effective against Neisseria meningitidis, meningococcal disease continues to be a major global health problem, particularly in the very young. Serogroup A meningococci cause large epidemics in sub-Saharan Africa, whilst serogroups B and C organisms are responsible for ...


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    authors: Borrow R,Balmer P,Miller E

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  • Shedding of live vaccine virus, comparative safety, and influenza-specific antibody responses after administration of live attenuated and inactivated trivalent influenza vaccines to HIV-infected children.

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  • The adjuvant CLDC increases protection of a herpes simplex type 2 glycoprotein D vaccine in guinea pigs.

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    authors: Bernstein DI,Farley N,Bravo FJ,Earwood J,McNeal M,Fairman J,Cardin R

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    authors: Radford AD,Bennett M,McArdle F,Dawson S,Turner PC,Glenn MA,Gaskell RM

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Davidkin I,Peltola H,Leinikki P,Valle M

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    pub_type: 杂志文章


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    更新日期:2017-12-19 00:00:00

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    pub_type: 杂志文章


    authors: Resti M,Azzari C,Mannelli F,Rossi ME,Lionetti P,Vierucci A

    更新日期:1997-08-01 00:00:00