Sleep and sleep regulation in the ferret (Mustela putorius furo).


:We investigated sleep-wake (S-W) architecture and sleep regulation in the ferret: a phylogenetically primitive mammal increasingly used in neurobiological studies. Twenty-four hour S-W baseline data were collected in eight adult ferrets. Seven ferrets were then sleep deprived for 6h at the beginning of the light period. Like other placental mammals, ferrets exhibited the main vigilance states of wakefulness, rapid-eye-movement (REM) sleep and non-REM (NREM) sleep. Interestingly, the amount of REM sleep in the ferret was considerably higher (24.01+/-1.61% of total recording time) than typically reported in placental mammals. Ferret sleep was homeostatically regulated as sleep deprivation produced a significant increase in NREM EEG delta power during the recovery period. Therefore, ferret sleep in most respects is comparable to sleep in other placental mammals. However, the large amount of REM sleep in this phylogenetically more ancient species suggests that REM sleep may have been present in greater amounts in early stages of mammalian evolution.


Behav Brain Res


Jha SK,Coleman T,Frank MG




Has Abstract


2006-09-15 00:00:00














  • The effects of hippocampal aspiration lesions on conditioning to the CS and to a background stimulus in trace conditioned suppression.

    abstract::Rats with hippocampal aspiration lesions or cortical control lesions were compared to sham operated controls in a trace conditioned suppression task, in which a long-lasting background stimulus played the role of more conventional contextual cues. In all three surgical treatment groups, conditioning to the explicit co...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Rawlins JN,Tanner J

    更新日期:1998-03-01 00:00:00

  • Injury during adolescence leads to sex-specific executive function deficits in adulthood in a pre-clinical model of mild traumatic brain injury.

    abstract::Adolescents are more likely than adults to develop chronic symptoms, such as impulsivity and difficulty concentrating, following a mild traumatic brain injury (mTBI) which may relate to disruption of pre-frontal cortex (PFC development). During adolescence the PFC is undergoing extensive remodelling, driving maturatio...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Kaukas L,Holmes JL,Rahimi F,Collins-Praino L,Corrigan F

    更新日期:2020-12-14 00:00:00

  • Differential effects of social and novelty enrichment on individual differences in impulsivity and behavioral flexibility.

    abstract::Early life experience profoundly impacts behavior and cognitive functions in rats. The present study investigated how the presence of conspecifics and/or novel objects, could independently influence individual differences in impulsivity and behavioral flexibility. Twenty-four rats were reared in an isolated condition,...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Wang MZ,Marshall AT,Kirkpatrick K

    更新日期:2017-06-01 00:00:00

  • Unilateral frontal cortex ablation producing neglect causes time-dependent changes in striatal glutamate receptors.

    abstract::This study's goal is to identify adaptations involving striatal glutamate (GLU) or dopamine (DA) receptors that may contribute to recovery of function following cortical injury. Unilateral aspiration of the medial agranular region of frontal cortex (AGm) in rats produces neglect of contralateral stimuli. Pharmacologic...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Vargo JM,Marshall JF

    更新日期:1996-05-01 00:00:00

  • Differential outcomes aid the formation of categorical relationships between stimuli.

    abstract::The differential outcome effect is when learning is enhanced through the application of different outcomes to different conditions of a task. Here we explore whether one difference in learning with differential outcomes is an enhanced categorisation of objects. We demonstrate that participants learning conditional dis...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Easton A,Child S,Lopez-Crespo G

    更新日期:2011-09-12 00:00:00

  • Electrophysiological correlates of category goodness.

    abstract::We report the results obtained from a behavioural and electrophysiological study. A synthesised continuum going from labial /ba/ to retroflex /da/ through dental /da/ was tested for category goodness. Native English speakers rated different tokens from each category as good, bad or ambiguous. The results showed that n...

    journal_title:Behavioural brain research

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Rivera-Gaxiola M,Johnson MH,Csibra G,Karmiloff-Smith A

    更新日期:2000-07-01 00:00:00

  • Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats.

    abstract:UNLABELLED:Evidence from in situ studies supports the role of anti-apoptotic factors in the antidepressant responses of certain psychotropics. The availability of anti-ceramidase pro-apoptocic compound (LCL385) provides an opportunity to test in vivo the relation between hippocampal apopotosis and learned helplessness....

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Nahas Z,Jiang Y,Zeidan YH,Bielawska A,Szulc Z,Devane L,Kalivas P,Hannun YA

    更新日期:2009-01-30 00:00:00

  • Human avoidance and approach learning: evidence for overlapping neural systems and experiential avoidance modulation of avoidance neurocircuitry.

    abstract::Adaptive functioning is thought to reflect a balance between approach and avoidance neural systems with imbalances often producing pathological forms of avoidance. Yet little evidence is available in healthy adults demonstrating a balance between approach and avoidance neural systems and modulation in avoidance neuroc...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Schlund MW,Magee S,Hudgins CD

    更新日期:2011-12-01 00:00:00

  • Neural cell adhesion molecule (NCAM) null mice do not show a deficit in odour discrimination learning.

    abstract::Polysialylated neural cell adhesion molecule (PSA-NCAM) is predominantly expressed during development where it regulates biological functions including axon targeting and neuronal precursor cell migration. Although dramatically down regulated after birth in most regions of the nervous system, PSA-NCAM remains highly e...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Schellinck HM,Arnold A,Rafuse VF

    更新日期:2004-07-09 00:00:00

  • Zebrafish (Danio rerio) responds differentially to stimulus fish: the effects of sympatric and allopatric predators and harmless fish.

    abstract::The zebrafish has been an excellent model organism of developmental biology and genetics. Studying its behavior will add to the already strong knowledge of its biology and will strengthen the use of this species in behavior genetics and neuroscience. Anxiety is one of the most problematic human psychiatric conditions....

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Bass SL,Gerlai R

    更新日期:2008-01-10 00:00:00

  • Gene and stress history interplay in emergence of PTSD-like features.

    abstract::Systematically distinguishing genetic liability from other contributing factors is critical for designing a preventive strategy for post-traumatic stress disorder (PTSD). To address this issue, we investigated a murine model exposing C57BL/6j, DBA/2j and BALB/cj mice to repeated stress via exposure to conspecific aggr...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Chakraborty N,Meyerhoff J,Gautam A,Muhie S,Jibitu M,De Lima TC,Hammamieh R,Jett M

    更新日期:2015-10-01 00:00:00

  • Non-effective increase of fMRI-activation for motor performance in elder individuals.

    abstract::Motor performance declines with increasing age and it has been proposed that elder people might compensate for these deficits with increased cerebral activation. However, it is not known, whether increased activation - especially in motor areas of the contralateral and the ipsilateral cerebral hemisphere - might effec...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Loibl M,Beutling W,Kaza E,Lotze M

    更新日期:2011-10-01 00:00:00

  • Acute and chronic alcohol administration: effects on performance of zebrafish in a latent learning task.

    abstract::Alcohol abuse is a major medical problem. Zebrafish have been proposed to model alcohol related human disorders. Alcohol impairs learning and memory. Here, we analyze the effects of alcohol on performance of zebrafish in a recently developed latent learning paradigm. We employ a 2×3×2 experimental design (chronic×acut...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Luchiari AC,Salajan DC,Gerlai R

    更新日期:2015-04-01 00:00:00

  • Synthetic cathinones and their phenethylamine analogues produce distinct psychomotor and reward behavior in crayfish.

    abstract::Synthetic cathinones share potent sympathomimetic properties with amphetamines due to their shared phenethylamine backbone. Despite recent work focused on understanding the behavioral effects of synthetic cathinones, a systematic comparison of neuropharmacology, behavior, and physiological effects with other stimulant...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Gore S,van Staaden MJ,Sprague JE,Huber R

    更新日期:2020-02-03 00:00:00

  • Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice.

    abstract::Chronic restraint stress (CRS) causes hippocampal neurodegeneration and hippocampus-dependent cognitive deficits. Flupirtine represents neuroprotective effects and we have previously shown that flupirtine can protect against memory impairment induced by acute stress. The present study aimed to investigate whether flup...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Huang P,Li C,Fu T,Zhao D,Yi Z,Lu Q,Guo L,Xu X

    更新日期:2015-07-15 00:00:00

  • Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression.

    abstract::Accumulating evidence shows that stressful events evoke molecular alterations in the brain, considered a pathology in major depressive disorder (MDD). However, the abnormalities of neurotransmissions as well as intracellular signaling pathways affected by chronic stress in brain have not been fully explored. We invest...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Lu Q,Mouri A,Yang Y,Kunisawa K,Teshigawara T,Hirakawa M,Mori Y,Yamamoto Y,Libo Z,Nabeshima T,Saito K

    更新日期:2019-10-17 00:00:00

  • Persistence of primate hand preference despite initial training to the contrary.

    abstract::Forty-six stumptail monkeys were tested for hand preference on a simple reaching task. Initial repeated reaches with the hand chosen for the first reach went unrewarded. All reaches following and including the earliest reach with the opposite hand were rewarded and were used to calculate overall hand preference for th...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Lehman RA

    更新日期:1980-12-01 00:00:00

  • Subchronic use of rivastigmine increases procognitive flexibility across multimodal behavioral tasks in healthy male rats.

    abstract::Rivastigmine (RVT) is a reversible inhibitor of cholinesterase approved worldwide for the treatment of cognitive dysfunctions, especially in Alzheimer's disease. Most previous pre-clinical studies have examined the effects of RVT treatment in a wide variety of pathological research models. Nonetheless, the effects of ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Hormigo S,Rodriguez-Lorenzana A,Castro-Salazar E,Millian-Morell L,López DE

    更新日期:2019-12-30 00:00:00

  • Affective profiling for anxiety-like behavior in a rodent model of mTBI.

    abstract::Mild traumatic brain injury is a common outcome of blast exposure, and current literature indicates high rates of comorbid posttraumatic stress disorder (PTSD) in military personnel. Blast-exposed rats display PTSD-like behavior, suggesting relationships may exist between PTSD and blast exposure. Other studies demonst...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Statz JK,Ciarlone SL,Goodrich JA,McCarron RM,Walker PB,Norris JN,Ahlers ST,Tschiffely AE

    更新日期:2019-08-05 00:00:00

  • Development of early motor learning and topical motor skills in a model of cerebellar degeneration.

    abstract::The development of motor learning and topical motor skills has been studied during the first month of life in neurodeficient Lurcher mutant mice derived from C3H strain. The examination of motor functions was conducted using four methods when animals were consecutively placed on: a horizontal wire, a rotating cylinder...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Krízková A,Vozeh F

    更新日期:2004-04-02 00:00:00

  • The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat.

    abstract::Environmental enrichment (EE) involves enhancing an animal's environment, with the goal of improving animal welfare. Though a well-established discipline, the consequences of EE on behavioural pharmacological tests have not been extensively examined. The purpose of this study was to examine the consequences of EE (or ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Simpson J,Kelly JP

    更新日期:2012-10-01 00:00:00

  • Successive negative contrast effect in instrumental runway behaviour: a study with Roman high- (RHA) and Roman low- (RLA) avoidance rats.

    abstract::It has been recently shown that Roman high- (RHA) and low- (RLA) avoidance rats show behavioural divergence in successive negative contrast (SNC) induced in one-way avoidance learning [Torres C, Cándido A, Escarabajal MD, de la Torre L, Maldonado A, Tobeña A, et al. Successive negative contrast effect in one-way avoid...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Rosas JM,Callejas-Aguilera JE,Escarabajal M,Gómez MJ,de la Torre L,Agüero A,Tobeña A,Fernández-Teruel A,Torres C

    更新日期:2007-12-11 00:00:00

  • Maternal exercise during gestation and lactation decreases high-fat diet preference by altering central reward system gene expression in adult female offspring from high-fat fed dams.

    abstract::Exposure to maternal high-fat (HF) diet during gestation and lactation alters adult offspring's feeding behavior and diet preference. However, the impact of maternal exercise on offspring's diet preference and reward system development is less studied. In this study, we investigate the effect of perinatal maternal exe...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Song L,Cui J,Wang N,Wang R,Yan J,Sun B

    更新日期:2020-07-15 00:00:00

  • Decreased proliferation in the adult rat hippocampus after exposure to the Morris water maze and its reversal by fluoxetine.

    abstract::Granular cell proliferation in the adult hippocampus decreases during aging and after chronic stress, while it can be increased by physical activity or treatment with the antidepressant fluoxetine. We investigated whether the physical and cognitive stimulation accompanied by stress in the commonly used Morris water ma...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Námestková K,Simonová Z,Syková E

    更新日期:2005-08-30 00:00:00

  • Tissue plasminogen activator modulates emotion in a social context.

    abstract::Tissue plasminogen activator (tPA) is known to play physiologically and pathologically crucial roles in the central nervous system. However, it is still obscure whether it affects social behavior. We investigated social behavior and neuronal activation after social stimulation in tPA knockout (KO) mice. In a resident-...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Nakamura K,Takabe A,Shimizu F,Takahashi M,Matsuo O,Mitsui S

    更新日期:2015-03-15 00:00:00

  • Perforant path stimulation in rats produces seizures, loss of hippocampal neurons, and a deficit in spatial mapping which are reduced by prior MK-801.

    abstract::Severe temporal lobe epilepsy in humans is often associated with loss of neurons in the hippocampus and memory deficits. In Experiment 1, 60 min of continuous electrical stimulation of the perforant path sufficient to produce seizures resembling status epilepticus and loss of hilar and pyramidal cells in the hippocamp...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Kelsey JE,Sanderson KL,Frye CA

    更新日期:2000-01-01 00:00:00

  • The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease.

    abstract::Increasing evidence suggests that disruptions of synaptic functions correlate with the severity of cognitive deficit in Alzheimer's disease (AD). Our previous study demonstrated that baicalein enhances long-term potentiation (LTP) in acute rat hippocampal slices and improves hippocampus-dependent contextual fear condi...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Gu XH,Xu LJ,Liu ZQ,Wei B,Yang YJ,Xu GG,Yin XP,Wang W

    更新日期:2016-09-15 00:00:00

  • Hippocampal BDNF treatment facilitates consolidation of spatial memory in spontaneous place recognition in rats.

    abstract::In order to investigate the role of brain-derived neurotrophic factor (BDNF) in the consolidation of spatial memory, we examined the relationship between the increase of hippocampal BDNF and the establishment of long-term spatial memory in spontaneous place recognition test in rats. The test consisted of a sample phas...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Ozawa T,Yamada K,Ichitani Y

    更新日期:2014-04-15 00:00:00

  • Galactosilated dopamine increases attention without reducing activity in C57BL/6 mice.

    abstract::Different strategies can be used to carry dopamine into the brain such as L-Dopa precursors or galactosilated form of DA (GAL-DA). The aim of this study was to investigate whether GAL-DA would reduce hyperactivity and increase non-selective attention (NSA) in a mouse model of attention deficit hyperactivity disorder (...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Ruocco LA,Viggiano D,Pignatelli M,Iannaccone T,Rimoli MG,Melisi D,Curcio A,De Lucia S,Carboni E,Gironi Carnevale UA,de Caprariis P,Sadile AG

    更新日期:2008-03-05 00:00:00

  • Post-stroke protection from maladaptive effects of learning with the non-paretic forelimb by bimanual home cage experience in C57BL/6 mice.

    abstract::Behavioral experience, in the form of skilled limb use, has been found to impact the structure and function of the central nervous system, affecting post-stroke behavioral outcome in both adaptive and maladaptive ways. Learning to rely on the less-affected, or non-paretic, body side is common following stroke in both ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章


    authors: Kerr AL,Wolke ML,Bell JA,Jones TA

    更新日期:2013-09-01 00:00:00