Hypocalcemic heart failure in thalassemic patients.

Abstract:

:Hypocalcemic cardiomyopathy in primary or secondary hypoparathyroidism is usually refractory to conventional treatment of cardiac failure. We report the case of a thalassemic patient with severe cardiac failure that might have been attributed to several factors, such as hemosiderosis, hypomagnesemia, and hypocalcemia, refractory to conventional cardiac therapy. Cardiac echocardiography showed impaired biventricular performance, and laboratory analyses revealed hypoparathyroidism due to hemosiderosis. When concomitant treatment of heart failure and calcium supplementation was initiated, correction of hypocalcemia resulted in clinical and laboratory improvement, providing strong evidence in support of our hypothesis about hypocalcemic myocardiopathy.

journal_name

Int J Hematol

authors

Tsironi M,Korovesis K,Farmakis D,Deftereos S,Aessopos A

doi

10.1532/IJH97.E0532

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

314-7

issue

4

eissn

0925-5710

issn

1865-3774

pii

Y35J582344416J44

journal_volume

83

pub_type

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