Comparison of four different serological methods for detection of antibodies to Borrelia burgdorferi in erythema migrans.

Abstract:

:Three different enzyme-linked immunosorbent assays (ELISA) and Western blot were compared in regard to the detection of antibodies to Borrelia burgdorferi in sera from 100 patients with erythema migrans and from 100 controls. For IgG detection, a commercial indirect ELISA kit with flagellum antigen (flagellum ELISA) was significantly more sensitive than the routinely-used indirect ELISA with sonicated whole-cell antigen (sonicate ELISA) (p = 0.008). The difference in positivity in the IgM test was of borderline significance (p = 0.058). An IgM antibody-capture ELISA with sonicated whole-cell antigen (capture ELISA) was significantly more sensitive than either the IgM sonicate ELISA (p less than 0.001) or IgM flagellum ELISA (p less than 0.001). With the Western blot pattern chosen as the criterion for positivity, IgM Western blot was at least equal to IgM capture ELISA in terms of the number of positive erythema migrans sera, but a frequent discrepancy between these two tests was noted as to positivity in individual sera. IgG Western blot was considered to be of less value for the diagnosis of current disease due to a high occurrence of positivity among controls.

journal_name

Acta Derm Venereol

authors

Olsson I,von Stedingk LV,Hanson HS,von Stedingk M,Asbrink E,Hovmark A

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

127-33

issue

2

eissn

0001-5555

issn

1651-2057

journal_volume

71

pub_type

临床试验,杂志文章
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    doi:10.2340/0001555575482483

    authors: Yamamoto T,Katayama I,Nishioka K

    更新日期:1995-11-01 00:00:00

  • Protective effect of zinc on keratinocyte activation markers induced by interferon or nickel.

    abstract::Zinc therapies exert beneficial effects in several cutaneous pathologies through their antiinflammatory properties, but target cells and mechanisms of action are still uncertain. We wondered whether markers of the keratinocyte activation state, such as the expression of immune surface antigens (ICAM-1 and HLA-DR) and ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555751923

    authors: Guéniche A,Viac J,Lizard G,Charveron M,Schmitt D

    更新日期:1995-01-01 00:00:00

  • Hand eczema: an evaluation of the frequency of atopic background and the difference in clinical pattern between patients with and without atopic dermatitis.

    abstract::In a prospective study of 63 patients with long-lasting hand eczema, a diagnosis of atopic dermatitis could be established in 49%. Comparison between patients with atopic dermatitis and those without atopic dermatitis showed that the hand eczema pattern differed very little between the groups. Hyperlinearity was signi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Svensson A

    更新日期:1988-01-01 00:00:00

  • Affinity of 3H-8-MOP to human chromosomes and cells.

    abstract::Human leukocytes and fibroblasts were cultured in medium containing 3H-8-methoxypsoralen (10(-6) M and 3.3 X 10(-6) M). At different stages during the culturing period the cells were exposed to ultraviolet light (1, 2, and 10 J/cm2). After the culture period the slides for chromosome analysis and smears of the cells w...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Wulf HC,Niebuhr E

    更新日期:1980-01-01 00:00:00

  • Expression of CCR2 on monocytes and macrophages in chronically inflamed skin in atopic dermatitis and psoriasis.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550410034444

    authors: Vestergaard C,Just H,Baumgartner Nielsen J,Thestrup-Pedersen K,Deleuran M

    更新日期:2004-01-01 00:00:00

  • Cutaneous Manifestations of Granulomatosis with Polyangiitis: A Case Series Study.

    abstract::The aim of this study was to determine the prevalence and type of cutaneous manifestations which occur in patients with granulomatosis with polyangiitis and to explore the potential association between cutaneous and systemic involvement in these patients. A retrospective case series study was designed, including all g...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3506

    authors: Montero-Vilchez T,Martinez-Lopez A,Salvador-Rodriguez L,Del Carmen Ramírez-Barberena M,Tercedor-Sanchez J,Molina-Leyva A,Arias-Santiago S

    更新日期:2020-05-28 00:00:00

  • Patch testing with markers of fragrance contact allergy. Do clinical tests correspond to patients' self-reported problems?

    abstract::The aim of the present study was to investigate the relationship between patients' own recognition of skin problems using consumer products and the results of patch testing with markers of fragrance sensitization. Eight hundred and eighty-four consecutive eczema patients, 18-69 years of age, filled in a questionnaire ...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章

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    更新日期:1997-03-01 00:00:00

  • Microvessel density and expression of vascular endothelial growth factor and its receptors in different subtypes of primary cutaneous B-cell lymphoma.

    abstract::A proangiogenic micromilieu is associated with a worse prognosis in systemic lymphoma. Hence, targeting the tumour microenvironment and its vasculature has evolved as a promising novel treatment strategy. The role of tumour neoangiogenesis in cutaneous B-cell lymphoma, however, has not yet been elucidated. Therefore, ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1589

    authors: Wobser M,Siedel C,Kneitz H,Bröcker EB,Goebeler M,Houben R,Geissinger E

    更新日期:2013-11-01 00:00:00

  • The relation between lichen planus and hepatitis C: a case report.

    abstract::A case of simultaneous occurrence of lichen planus (LP) and hepatitis C in the same patient is presented. The patient had received treatment with interferon alpha for her chronic liver disease, and the association between LP, hepatitis C and interferon alpha treatment is discussed. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:101080/000155572380

    authors: Agner T,Fogh H,Weismann K

    更新日期:1992-09-01 00:00:00

  • Structural analogues inhibit the sensitizing capacity of carvone.

    abstract::The aim of the study was to investigate the effect of non-allergenic structural analogues on the sensitizing potential of carvone, a fragrance allergen. The possibility that one molecule might inhibit the allergenic activity of another molecule has been debated for 25 years. The Research Institute for Fragrance Materi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155501317208318

    authors: Karlberg AT,Nilsson AM,Luthman K,Nilsson JL

    更新日期:2001-11-01 00:00:00

  • Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/00015555-2220

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    更新日期:2016-02-01 00:00:00

  • Progressive hyperpigmentation and generalized lentiginosis without associated systemic symptoms: a rare hereditary pigmentation disorder in south-east Germany.

    abstract::Familial progressive hyperpigmentation is rarely described in the literature. We report on five patients from three different families presenting with a peculiar progressive pigmentary disorder. The patients show a progressive diffuse, partly blotchy, hyperpigmentation, intermixed with scattered small hypopigmented ma...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550310005780

    authors: Zanardo L,Stolz W,Schmitz G,Kaminski W,Vikkula M,Landthaler M,Vogt T

    更新日期:2004-01-01 00:00:00

  • Angiokeratomas in Fabry's disease and Fordyce's disease: successful treatment with copper vapour laser.

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    pub_type: 杂志文章

    doi:10.2340/0001555573133135

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    更新日期:1993-04-01 00:00:00

  • Granulomatous vasculitis as a complication of potassium iodide treatment for Sweet's syndrome.

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    pub_type: 杂志文章

    doi:

    authors: Eeckhout E,Willemsen M,Deconinck A,Somers G

    更新日期:1987-01-01 00:00:00

  • Red lunulae in severe alopecia areata.

    abstract::The development of red nail lunulae has been extremely rarely described in alopecia areata. We observed 2 patients, a 30-year-old woman and a 61-year-old man, both suffering from severe alopecia areata, and having red lunulae. The colour changes, which developed a few weeks after the acute onset of hair loss, disappea...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572203205

    authors: Bergner T,Donhauser G,Ruzicka T

    更新日期:1992-01-01 00:00:00

  • The histological and immunohistochemical pattern of positive patch test reactions to gold sodium thiosulfate.

    abstract::Gold sodium thiosulfate, inserted in the patch test standard series, gives a surprisingly high yield of positive reactions, about 10% of tested eczema patients, but with a low degree of clinical relevance. A histopathological study on patch test reactions was carried out in patients selected because of a combined cont...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555574417423

    authors: Möller H,Larsson A,Björkner B,Bruze M

    更新日期:1994-11-01 00:00:00

  • Immunoglobulin E in psoriasis evaluated by paper radioimmunosorbent and paper enzyme-immunosorbent tests.

    abstract::Serum IgE concentrations were determined by the paper radioimmunosorbent test in 56 patients with psoriasis and 50 normal controls, and by the paper enzyme-immunosorbent test in 32 of these patients and 50 controls. Elevated IgE levels were found in 26 (46%) of 56 patients with psoriasis and in 1 normal control (2%). ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Chen ZY,Ainsworth SK,Khan T,Pilia PA,Dobson RL

    更新日期:1985-01-01 00:00:00

  • A study of bone formation in osteoma cutis employing biochemical, histochemical and in situ hybridization techniques.

    abstract::A female presenting multiple osteoma cutis lesions without underlying endocrinological disturbance was studied. Histologically, lesions revealed true bone formation with multiple osteoblastic cells. This was confirmed by demonstrating high alkaline phosphatase activity and osteonectin expression in osteoma cutis lesio...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572172174

    authors: Oikarinen A,Tuomi ML,Kallionen M,Sandberg M,Väänänen K

    更新日期:1992-01-01 00:00:00

  • Analysis of high-dose intravenous immunoglobulin therapy in 16 patients with refractory autoimmune blistering skin disease: high efficacy and no serious adverse events.

    abstract::High-dose intravenous immunoglobulin (IVIG) therapy is used in patients with severe autoimmune blistering diseases that are refractory to standard immunosuppressive therapy. To determine the efficacy and frequency of adverse events of IVIG therapy, we retrospectively analysed data for 16 patients with pemphigus vulgar...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

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    authors: Seidling V,Hoffmann JH,Enk AH,Hadaschik EN

    更新日期:2013-05-01 00:00:00

  • The Wiskott-Aldrich syndrome gene as a candidate gene for atopic dermatitis.

    abstract::Atopic dermatitis is a multifactorial disorder probably caused by environmental factors in combination with susceptibility genes. The clinical similarity between atopic dermatitis and the eczema manifestation in patients with Wiskott-Aldrich syndrome made the previously identified WAS gene in chromosome sub-band Xpl 1...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155501317140043

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  • Study of the Exposome Ageing-related Factors in the Spanish Population.

    abstract::To characterize the exposome of the Spanish population and its association with skin ageing a cross-sectional epidemiological study was conducted in men and women (18-60 years old). A total of 1,474 participants were included. Mean age (± standard deviation) was 40.84 ± 10.26 years. Most participants had Fitzpatrick s...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3500

    authors: Buendía-Eisman A,Prieto L,Abarquero M,Arias-Santiago S

    更新日期:2020-05-28 00:00:00

  • Effect of psoriasis heliotherapy on epidermal urocanic acid isomer concentrations.

    abstract::A noninvasive Finn Chamber sampling method and HPLC analysis were used to determine epidermal urocanic acid (UCA) concentrations of psoriasis patients during 4 weeks of heliotherapy on the Spanish Canary Islands and a follow-up period of 8 weeks. During heliotherapy the epidermal cis-UCA concentration increased from a...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/000155555571231233

    authors: Snellman E,Koulu L,Pasanen P,Lammintausta K,Neuvonen K,Ayräs P,Jansén CT

    更新日期:1992-01-01 00:00:00

  • Multiple keratoacanthomas, giant keratoacanthoma and keratoacanthoma centrifugum marginatum: development in a single patient and treatment with oral isotretinoin.

    abstract::A 78-year-old man is described, who over 18 years developed three different types of keratoacanthoma: multiple keratoacanthomas, keratoacanthoma centrifugum marginatum and giant keratoacanthoma. Histological examination of the different neoplasms showed similar changes, all typical of a keratoacanthoma. In situ hybrid...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555764042

    authors: Schaller M,Korting HC,Wolff H,Schirren CG,Burgdorf W

    更新日期:1996-01-01 00:00:00

  • Disutility in Patients with Hidradenitis Suppurativa: A Cross-sectional Study Using EuroQoL-5D.

    abstract::Disutility reflects the disability caused by a disease. The EuroQoL-5D (EQ-5D) questionnaire is a measure of health-related overall utility. The questionnaire has only been applied previously to a small number of patients with hidradenitis. In this study a survey of 421 patients with hidradenitis suppurativa was condu...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2129

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    更新日期:2016-02-01 00:00:00

  • Phylogenetic studies with pemphigus and pemphigoid antibodies.

    abstract::Indirect immunofluorescence (IF) studies were performed on skin from a variety of vertebrate specimens and IgG fractions from pemphigoid and pemphigus sera. Pemphigoid antigen was present in fish, amphibian, reptilian, avian and mammalian skin, whereas pemphigus antigen was observed in avian and mammalian skin only. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

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    authors: Diaz LA,Weiss HJ,Calvanico NJ

    更新日期:1978-01-01 00:00:00

  • Racial differences in experimental skin infection with Candida albicans.

    abstract::The forearm skin of 10 Caucasians and 10 American Negroes was inoculated with Candida albicans and the severity of the ensuing dermatitis as well as the population of Candida and other aerobes in the inoculum site have been assessed. Negroid skin proved to be less susceptible to irritation, even though it harboured a ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Rebora A,Guarrera M

    更新日期:1988-01-01 00:00:00

  • Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker's Naevus.

    abstract::Becker's naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder. Immunohistochemistry showed that epidermal expression of androgen receptors, oestrogen receptors (α, β) and progesterone receptors was higher in skin lesions of Be...

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    pub_type: 杂志文章

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  • Enzyme release from cultured human melanoma cells.

    abstract::The lysosomal enzyme beta-hexosaminidase and the melanocyte specific enzyme tyrosinase were examined in human melanoma cell cultures. The beta-hexosaminidase activity of the medium was approximately 40% of the total cellular activity after 24 h, while after 48 h the activity in the medium was twice that of the cells. ...

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  • Cutaneous infection with Mycobacterium fortuitum after localized microinjections (mesotherapy) treated successfully with a triple drug regimen.

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  • Malignant transformation of multiple familial trichoepithelioma: case report and literature review.

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    pub_type: 杂志文章,评审

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