Ultrasound screening for fetal anomalies in southern Sweden: a population-based study.

Abstract:

BACKGROUND:The accuracy of ultrasound in the diagnosis of congenital malformations has been the subject of many studies. Most of these are hospital-based studies over a limited period of years presenting high detection rates and also relatively high incidence of major malformations. We present here a large population-based study over a long period of years. METHODS:The prenatal diagnoses are compared with the diagnoses of the newborns and aborted fetuses, including autopsy results. The detection rate of some common structural malformations is studied. RESULTS:The overall detection rate of malformations in our study was 28.4%. We noticed an improved detection rate of heart defects and cleft lip during the study period. The prevalence of malformations in the population was 2.6%. The false positive diagnoses were few, 54 cases, and mainly of a mild nature. CONCLUSIONS:Ultrasound screening of fetal malformations in our population has a low false positive rate and even though the overall sensitivity is low, 28.4%, the detection rate for many common structural malformations is relatively good.

authors

Nikkilä A,Rydhstroem H,Källén B,Jörgensen C

doi

10.1080/00016340600676474

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

688-93

issue

6

eissn

0001-6349

issn

1600-0412

pii

743725784

journal_volume

85

pub_type

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