Primary chondrosarcoma of ethmoid bone in a 6-year-old child.


:Chondrosarcoma (CS) is a distinctly uncommon tumor in young patients and tends to be located in the extremities. Cartilaginous tumors in young patients are benign tumors. We report a case of a childhood CS in a 6-year-old boy who presented with right-sided proptosis. Radiological examination revealed a large destructive mass in right ethmoidal sinus extending into the surrounding sphenoidal sinus, intracranially, and the into right orbit, causing proptosis. Biopsy of the mass showed characteristic features of a well-differentiated CS. There are no reports of CS presenting as proptosis and arising from ethmoid bone. This case highlights the rarity of this tumor with regard to age of presentation and site of origin.


Ann Diagn Pathol


Mahesha V,Goyal R,Vaiphei K,Nada R,Gupta AK




Has Abstract


2006-06-01 00:00:00














  • PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature.

    abstract:BACKGROUND AND AIMS:Programmed death ligand 1 (PD-L1), an immune check point inhibitor, is known to be expressed in several malignancies and is being considered as a prognostic factor and a potential immunotherapeutic target. The aim of this study was to characterize PD-L1 expression in thymomas and to determine correl...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Guleria P,Husain N,Shukla S,Kumar S,Parshad R,Jain D

    更新日期:2018-06-01 00:00:00

  • Malignant glandular lesions and glandular differentiation in invasive/noninvasive urothelial carcinoma of the urinary bladder.

    abstract::Although the lumen of the urinary bladder is covered with only urothelial epithelium, malign glandular lesions (eg, nonurachal adenocarcinoma) and benign lesions (eg, cystitis cystica and cystitis glandularis) can also rarely occur in this site due to its characteristic embryologic development. Glandular differentiati...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Behzatoğlu K

    更新日期:2011-12-01 00:00:00

  • Expression of vitamin D receptor in clear cell papillary renal cell carcinoma.

    abstract::Clear cell papillary renal cell carcinoma (ccpRCC) is a recently recognized subtype of renal cell carcinoma. In this study, we investigated the clinicopathological and immunohistochemical features in a group of 26 cases of ccpRCC, with a special emphasis on the expression of vitamin D receptor (VDR). The mean age of p...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Wang Y,Ding Y,Qin C,Gu M,Wang Z,Han C,Liu X,Li H,Hua H

    更新日期:2018-10-01 00:00:00

  • Melanocytic "ball-in-mitts" and "microalveolar structures" and their role in the development of cellular blue nevi.

    abstract::To test the hypothesis of whether cellular blue nevi (CBN) may originate from "ordinary" compound and dermal nevi, a total of 275 melanocytic nevi including 59 CBN, 34 ordinary blue nevi, 87 combined nevi (including 43 so-called clonal nevi), 35 deep penetrating nevi, and 60 ordinary compound and dermal nevi (30 of ea...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Kazakov DV,Michal M

    更新日期:2007-06-01 00:00:00

  • Breast abnormalities in patients with cystic fibrosis: previously unrecognized changes.

    abstract::We reviewed breast tissue from 19 female postpubertal and three prepubertal patients with cystic fibrosis to determine the histopathologic changes present. Autopsy material was available from 19 patients who died from complications of cystic fibrosis. Two patients had lumpectomies for breast carcinoma and an additiona...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Garcia FU,Galindo LM,Holsclaw DS Jr

    更新日期:1998-10-01 00:00:00

  • FTO mRNA expression in the lower quartile is associated with bad prognosis in clear cell renal cell carcinoma based on TCGA data mining.

    abstract::Fat mass and obesity associated (FTO) is a protein-coding gene, also known as the obesity gene. It has been reported previously to be associated with a variety of malignant cancers, such as breast, thyroid and acute myeloid leukemia. The aim of the present study was to investigate the FTO mRNA expression in human clea...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Wen L,Yu Y,Lv H,He Y,Yang B

    更新日期:2019-02-01 00:00:00

  • Lymphoepithelioma-like carcinoma of the breast: report of a case mimicking lymphoma.

    abstract::Only 10 cases of lymphoepithelioma-like carcinoma of the breast have been reported in the literature. This report adds one more case to the published literature. A 62-year-old woman presented with a mass in her left breast on physical examination. The mammographic images showed a 3.0 cm, poorly defined mass in the upp...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Sanati S,Ayala AG,Middleton LP

    更新日期:2004-10-01 00:00:00

  • Loss of ELF3 immunoexpression is useful for detecting oral squamous cell carcinoma but not for distinguishing between grades of epithelial dysplasia.

    abstract::Early diagnosis and targeted therapy are crucial to mitigating the morbidity and mortality of oral squamous cell carcinoma. Among the potentially malignant oral disorders, epithelial dysplasia has known association with malignant transformation, but defensible gradation of dysplasia severity presents unmet challenges....

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: AbdulMajeed AA,Dalley AJ,Farah CS

    更新日期:2013-08-01 00:00:00

  • Cystic schwannoma of the pancreas.

    abstract::Intrapancreatic schwannoma is a rare neoplasm. We report a case of a 46-year-old man with a cystic schwannoma in the head of the pancreas. This tumor, based on clinical manifestations and radiologic features, was initially suspected to be a cystic mucinous tumor of the pancreas or a pseudocyst. Histologically, the tum...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Tan G,Vitellas K,Morrison C,Frankel WL

    更新日期:2003-10-01 00:00:00

  • Processing the entire capsule in thyroid follicular lesions improves diagnostic accuracy.

    abstract:BACKGROUND:There is contradictory evidence in literature with respect to diagnosis and management of follicular lesions of the thyroid gland. From surgical pathology stand point, pathologists require submission and processing of entire capsule for microscopic evaluation. This can be extremely challenging especially in ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Hamza A,Khawar S,Alrajjal A,Salehi S

    更新日期:2019-04-01 00:00:00

  • Adelaide's blackbirding pathologist.

    abstract::Archibald Watson (1849-1940) was the inaugural Elder Professor of Anatomy at the University of Adelaide. He held the position from 1885 to 1919, having previously trained in Gottingen, Paris, and London under some of the most eminent physicians of those times. Before he started his medical studies, he, Dr James Patric...

    journal_title:Annals of diagnostic pathology

    pub_type: 传,历史文章,杂志文章


    authors: Allen PW

    更新日期:1998-06-01 00:00:00

  • The surgical and cytopathology of viral infections: utility of immunohistochemistry, in situ hybridization, and in situ polymerase chain reaction amplification.

    abstract::The diagnosis of viral infections is an important part of the daily work of a surgical and cytopathologist. Some viral infections, such as human papillomavirus infection of the lower genital tract, are seen commonly, whereas others, such as fatal enteroviral infection, cannot be diagnosed on routine histological exami...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Nuovo GJ

    更新日期:2006-04-01 00:00:00

  • Mammary analogue secretory carcinoma of salivary glands: a clinicopathologic study of 11 cases.

    abstract::Mammary analogue secretory carcinoma (MASC) is a recently described tumor sharing the histologic, immunohistochemical, and molecular profile of secretory carcinoma of breast. We aimed to evaluate the morphologic and histochemical features needed/required for the diagnosis of MASC without adjunct of molecular analysis....

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Din NU,Fatima S,Kayani N

    更新日期:2016-06-01 00:00:00

  • Distribution of lymphoid neoplasms in Northwest China: Analysis of 3244 cases according to WHO classification in a single institution.

    abstract::To explore the distribution of lymphoid neoplasms in Northwest China, the clinical and pathological data of lymphoma patients from 2006 to 2014 were analyzed according to the WHO classification in Xijing Hospital. Of the 3244 cases, mature B-cell neoplasms occupied 60.7%, while mature T/NK-cell neoplasms and Hodgkin's...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Cao C,Feng J,Gu H,Tang H,Xu L,Dong H,Dong B,Shu M,Bai Q,Liang R,Zhang T,Yang L,Wang Z,Chen X,Gao G

    更新日期:2018-06-01 00:00:00

  • Pseudosarcoma in Paget's disease of bone.

    abstract::The appearance of a sarcoma of bone is a well-recognized complication of Paget's disease. The most common type of such a sarcoma is osteosarcoma. Much less common are soft tissue lesions adjoining the pagetic bone that clinically and radiologically simulate sarcoma but histologically represent exaggerated periosteal b...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Lamovec J,Rener M,Spiler M

    更新日期:1999-04-01 00:00:00

  • Pancreatic endocrine tumor coexistent with serous microcystic adenoma: report of a case and review of the literature.

    abstract::Serous cystadenomas of the pancreas have been classified as benign exocrine tumors. There have been rare cases of malignant behavior, and in exceptional cases, coexisting neoplasms have been reported. We report a case of a coexistent neuroendocrine tumor identified within a serous cystadenoma in a 78-year-old woman, w...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Alasio TM,Vine A,Sanchez MA,Dardik H

    更新日期:2005-08-01 00:00:00

  • Functioning adrenocortical oncocytoma: a case report and review of the literature.

    abstract::Adrenocortical oncocytoma is exceptionally rare. Most of these tumors are benign and nonfunctioning. We report a case of functioning adrenocortical oncocytoma located in the right adrenal gland in a 53-year-old woman who presented with Cushing's syndrome. The tumor was small, with exclusively oncocytic histologic feat...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Xiao GQ,Pertsemlidis DS,Unger PD

    更新日期:2005-10-01 00:00:00

  • Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene.

    abstract::A 34-year-old pregnant woman with bilateral kidney tumors 9.5 and 2.5 cm in maximum diameter is presented. The larger tumor was clear renal cell carcinoma. The smaller contralateral tumor was focally HMB45 positive and had unusual histomorphology, including features resembling clear renal cell carcinoma with features ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Petersson F,Michal M,Vaněček T,Hora M,Trivunic S,Halbhuber Z,Hes O

    更新日期:2011-10-01 00:00:00

  • Upregulation of inhibitory signaling receptor programmed death marker-1 (PD-1) in disease evolution from cutaneous lymphoid dyscrasias to mycosis fungoides and Sezary's syndrome.

    abstract:BACKGROUND:Negative immunoregulatory checkpoints impede effective immune responses to tumor and reduce the action of anticancer agents. One such example is programmed death marker-1 (PD-1), an inhibitory signaling receptor expressed on activated and regulatory T-cells. PD-1 expression was reported in a few reports, but...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Nguyen GH,Olson LC,Magro CM

    更新日期:2017-06-01 00:00:00

  • Utility of thin-layer preparations in the endometrial cytology: evaluation of benign endometrial lesions.

    abstract::The purpose of the current study was to examine the use of thin-layer cytologic (TLC) preparation compared to conventional cytologic preparation (CCP) in the normal endometrium (proliferative, secretory, atrophic) and endometrial glandular and stromal breakdown (EGBD). During a 6-month period, we compiled 158 cases by...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Norimatsu Y,Kouda H,Kobayashi TK,Moriya T,Yanoh K,Tsukayama C,Miyake Y,Ohno E

    更新日期:2008-04-01 00:00:00

  • Expression of dog1 in low-grade fibromyxoid sarcoma: A study of 19 cases and review of the literature.

    abstract::DOG1 is a highly-sensitive marker often included in the immunohistochemical panel for the diagnosis of gastrointestinal stromal tumors (GISTs). Recent research has shown that DOG1 may also be expressed by low-grade fibromyxoid sarcomas (LGFMSs); this may give rise to diagnostic error when the sarcoma is located in the...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Vallejo-Benítez A,Rodríguez-Zarco E,Carrasco SP,Pereira-Gallardo S,Brugal Molina J,García-Escudero A,Robles Frías A,Marcilla D,González-Cámpora R

    更新日期:2017-10-01 00:00:00

  • Phosphaturic mesenchymal tumors. Survey of 8 cases from a single Mexican medical institution.

    abstract::Phosphaturic mesenchymal tumor (PMT) is a morphologically heterogeneous soft tissue and bone neoplasm, producing a paraneoplastic syndrome due to phosphate wasting. These tumors produce fibroblast growth factor 23, which is implicated in renal tubule phosphate loss. Medical records of patients seen from 1999 to 2013 w...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Angeles-Angeles A,Reza-Albarrán A,Chable-Montero F,Cordova-Ramón JC,Albores-Saavedra J,Martinez-Benitez B

    更新日期:2015-12-01 00:00:00

  • The role of routine immunohistochemistry for Helicobacter pylori in gastric biopsy.

    abstract::Helicobacter pylori infection is associated with gastritis, gastric ulcer, gastric adenocarcinoma, and mucosal associated lymphoid tissue lymphoma. Documenting the presence of H pylori in a gastric biopsy is essential for appropriate patient care. Several special stains and immunohistochemistry (IHC) stain for H pylor...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Wang XI,Zhang S,Abreo F,Thomas J

    更新日期:2010-08-01 00:00:00

  • Elevated Mortalin correlates with poor outcome in hepatocellular carcinoma.

    abstract::Although several lines of evidence existed suggesting that Mortalin was linked with survival in malignant tumors; it has been barely described regarding the prognostic involvement of its expression in hepatocellular carcinoma (HCC). Herein, to understand the prognostic meaning of Mortalin expression, Immunohistochemis...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Cheng W,Zhang B,Zikeliyar M,Wang J,Jian H,Wu K,Zhang Y,Ding J

    更新日期:2019-10-01 00:00:00

  • So-called sclerosing hemangioma of lung: current concept.

    abstract::Sclerosing hemangioma of the lung is a rare neoplasm with polymorphic histologic features. Despite various patterns, there are 2 unifying cellular components: "surface cells" and "round cells." Although histogenesis has been debated for decades, most ultrastructural, immunocytochemical, and molecular studies strongly ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Kalhor N,Staerkel GA,Moran CA

    更新日期:2010-02-01 00:00:00

  • Measuring the dimension of invasive component in pT1 urothelial carcinoma in transurethral resection specimens can predict time to recurrence.

    abstract::Recurrences of nonmuscle-invasive urothelial bladder cancer are very common following resection. Predictive histopathologic variables in transurethral resection of bladder tumor (TURBT) specimens are of particular importance especially in determining the behavior of lamina propria-invasive tumors (high grade T1 stage)...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Hu Z,Mudaliar K,Quek ML,Paner GP,Barkan GA

    更新日期:2014-04-01 00:00:00

  • Cystic pancreatic schwannoma in a 46-year-old man.

    abstract::Pancreatic schwannomas are a rare benign mesenchymal neoplasm of the pancreas. They are thought to arise from the epineurium of either autonomic sympathetic or parasympathetic fibers, which course through the pancreas with the vagus nerve. Large pancreatic schwannomas often undergo cystic change, which causes them to ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Tafe LJ,Suriawinata AA

    更新日期:2008-08-01 00:00:00

  • Intestinal type adenocarcinoma: a previously unrecognized histologic variant of ductal carcinoma of the pancreas.

    abstract::Adenocarcinomas with intestinal differentiation have been described in a wide variety of anatomical sites. To our knowledge, however, ductal adenocarcinomas with intestinal phenotype have not been described in the pancreas. We report here 11 ductal carcinomas of the pancreas that were morphologically similar to coloni...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Albores-Saavedra J,Simpson K,Dancer YJ,Hruban R

    更新日期:2007-02-01 00:00:00

  • Osteopontin: a marker for invasive oral squamous cell carcinoma but not for potentially malignant epithelial dysplasias.

    abstract::This study aimed to evaluate and correlate osteopontin (OPN) expression in oral squamous cell carcinoma (OSCC) and potentially malignant disorders including oral leukoplakia and oral submucous fibrosis (OSMF). Expression of OPN was investigated in 140 samples including OSCC, oral leukoplakia, and OSMF with or without ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Routray S,Kheur SM,Kheur M

    更新日期:2013-10-01 00:00:00

  • Aggressive meningiomas involving the parotid gland.

    abstract::Parotid masses remain challenging secondary to the great diversity of primary tumors that may arise in the salivary glands and propensity for regional and even distant metastases to occur in this region. Meningioma must also be considered in the differential diagnosis of parotid masses, whether from direct extension, ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Joggerst KH,Langford LA,Williams MD

    更新日期:2012-04-01 00:00:00