Effects of green tea on urinary stone formation: an in vivo and in vitro study.


PURPOSE:We evaluated whether epigallocatechin gallate (EGCG), a main constituent of green tea polyphenols, could protect against cellular toxicity by oxalate and whether green tea supplementation attenuates the development of nephrolithiasis in an animal model. MATERIALS AND METHODS:Cells of the NRK-52E line were incubated with different concentrations of oxalate with and without EGCG, and toxicity and malondialdehyde assays were done to investigate the cytotoxic effect of oxalate and the anti-oxalate effect of EGCG.. In a second series of experiments, male Sprague-Dawley rats were divided into three groups. Group 1 animals (controls) were fed regular chow and drank water ad libitum; group 2 animals were fed chow containing 3% sodium oxalate with the administration of gentamicin (40 mg/kg) and drank water ad libitum; group 3 animals were fed the same diet as group 2 with gentamicin administration and drank only green tea. Rats were killed 4 weeks later after a 24-hour urine collection, and the kidneys were removed for morphologic examination. RESULTS:As oxalate concentrations increased, the number of surviving cells decreased, and the formation of free radicals increased. The administration of EGCG inhibited free-radical production induced by oxalate. Green tea supplementation decreased the excretion of urinary oxalate and the activities of urinary gammaglutamyltranspeptidase and N-acetylglucosaminidase. The number of crystals within kidneys in group 3 was significantly lower than in group 2. CONCLUSIONS:Green tea has an inhibitory effect on urinary stone formation, and the antioxidative action of EGCG is considered to be involved.


J Endourol


Journal of endourology


Jeong BC,Kim BS,Kim JI,Kim HH




Has Abstract


2006-05-01 00:00:00












  • Assessing the accuracy of endoscopic estimates of lesion size in urology using in vitro models of the urinary tract.

    abstract:BACKGROUND AND PURPOSE:Despite the frequency at which urologists endoscopically estimate lesion size, their accuracy has not been established. Our objectives were to determine the accuracy of cystoscopic and ureteroscopic estimates of lesion size using in vitro models of the urinary tract and to assess potential impact...

    journal_title:Journal of endourology

    pub_type: 杂志文章,随机对照试验


    authors: Massaro PA,Abdolell M,Norman RW

    更新日期:2013-09-01 00:00:00

  • "Stoneless" or Negative Ureteroscopy: A Reality in the Endourologic Routine or Avoidable Source of Frustration? Estimating the Risk Factors for a Negative Ureteroscopy.

    abstract:INTRODUCTION:A "Negative" ureteroscopy (URS) is defined as a URS in which no stone is found during the procedure. It may occur when the stone has already been passed spontaneously or when it is located outside the collecting system. The aim of the study was to outline risk factors for Negative-URS. MATERIALS AND METHO...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Katafigiotis I,Sabler IM,Heifetz EM,Rosenfeld A,Stavros S,Lorber A,Latke A,Yutkin V,Hidas G,Landau EH,Pode D,Gofrit ON,Duvdevani M

    更新日期:2018-09-12 00:00:00

  • Novel management of complicated renal artery aneurysm: laparoscopic nephrectomy and ex-vivo repair with heterotopic autotransplant.

    abstract:BACKGROUND AND PURPOSE:Renal artery aneurysm (RAA) is an infrequently seen disease entity but one with the potential for significant morbidity and mortality. Complications related to RAA include pain, hematuria, hypertension, and, rarely, rupture. Management is often based on symptomatology or, if symptoms are not pres...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Shirodkar SP,Bird V,Velazquez O,Ciancio G

    更新日期:2010-01-01 00:00:00

  • Impact of irrigation systems on stone migration.

    abstract:PURPOSE:To evaluate forces exerted on a stone with different ureteroscopic irrigation systems that could impact stone migration during ureteroscopy. MATERIALS AND METHODS:A 3-mm steel simulated stone was welded to a 3F stone basket. The basket wire was then backloaded into the working channel of a 4.5F Wolf semirigid ...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Hendlin K,Weiland D,Monga M

    更新日期:2008-03-01 00:00:00

  • Actively deflectable, flexible cystoscopes: no longer solely a diagnostic instrument.

    abstract::The recent evolution of actively deflectable, flexible endoscopes has included the flexible cystoscope. Improvements in optics, deflectability, and the size of the outer sheath and working channel have been accomplished. A superior flexible cystoscope is one with an outer sheath of 16F or less and working channel larg...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Grasso M,Beaghler M,Bagley DH,Strup S

    更新日期:1993-12-01 00:00:00

  • Robotic radical prostatectomy learning curve of a fellowship-trained laparoscopic surgeon.

    abstract:BACKGROUND AND PURPOSE:Several experienced practitioners of open surgery with limited or no laparoscopic background have adopted robot-assisted laparoscopic radical prostatectomy (RLRP) as an alternative to open radical prostatectomy (RRP), demonstrating outcomes comparable to those in large RRP and laparoscopic prosta...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Zorn KC,Orvieto MA,Gong EM,Mikhail AA,Gofrit ON,Zagaja GP,Shalhav AL

    更新日期:2007-04-01 00:00:00

  • Conductive heat: hot water-induced thermotherapy for ablation of prostatic tissue.

    abstract::Water-Induced Thermotherapy (WIT trade mark ) was developed to treat lower urinary tract symptoms (LUTS) and to reduce bladder outlet obstruction (BOO) secondary to benign prostatic hyperplasia (BPH). The principle is to produce heat-induced coagulative necrosis and secondary ablation of the obstructing hyperplastic t...

    journal_title:Journal of endourology

    pub_type: 杂志文章,评审


    authors: Muschter R

    更新日期:2003-10-01 00:00:00

  • Simple nephrectomy: retroperitoneal approach.

    abstract::Direct extraperitoneal surgery has become the preferred approach to laparoscopic nephrectomy since the introduction of the balloon dilation method. The lateral decubitus position provides good exposure, but the prone position is used at some centers to gain better exposure with the aid of gravity. The open conversion ...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Gaur DD

    更新日期:2000-12-01 00:00:00

  • Impact of real-time visualization of cystoscopy findings on procedural pain in female patients.

    abstract:BACKGROUND AND PURPOSE:We have previously shown that men tolerate office flexible cystoscopy better when they simultaneously view the monitor during their procedure. We sought to demonstrate similar effects of distraction on women undergoing rigid office cystoscopy. PATIENTS AND METHODS:100 consecutive women underwent...

    journal_title:Journal of endourology

    pub_type: 杂志文章,随机对照试验


    authors: Patel AR,Jones JS,Babineau D

    更新日期:2008-12-01 00:00:00

  • Percutaneous stone implantation in the pig kidney: a new animal model for lithotripsy research.

    abstract:PURPOSE:This report describes a new animal model for research on the parameters of shockwave delivery and the mechanisms of shockwave action in SWL. MATERIALS AND METHODS:Female pigs (approximately 45 kg) were anesthetized for creation of an upper pole peripheral caliceal access. The tract was dilated with a 30F Nephr...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Paterson RF,Lingeman JE,Evan AP,Connors BA,Williams JC Jr,McAteer JA

    更新日期:2002-10-01 00:00:00

  • Retroperitoneal laparoscopic nephroureterectomy and management options for the distal ureter.

    abstract::Radical nephroureterectomy, including en bloc excision of the ureter with a bladder cuff, is the standard treatment for upper tract transitional-cell carcinoma (TCC). This procedure requires either a flank and lower abdominal incision or an extended flank incision. Laparoscopic surgery for TCC has been used at several...

    journal_title:Journal of endourology

    pub_type: 杂志文章,评审


    authors: Kaouk JH,Savage SJ,Gill IS

    更新日期:2001-05-01 00:00:00

  • Balloon dilation of posterior urethral stricture secondary to radiation and cryotherapy in a patient with a functional artificial urethral sphincter.

    abstract::Severe urethral stricture disease as an isolated entity can be a management dilemma. In the patient described here, this problem was associated with prior external-beam radiation and cryosurgical ablation of the prostate, and a functional artificial urethral sphincter (AUS) had been placed. An attempt to relieve parti...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Westney OL,Del Terzo MA,McGuire EJ

    更新日期:1999-10-01 00:00:00

  • Laparoscopic orchidopexy in children.

    abstract:BACKGROUND:Cryptorchidism is a common condition in boys. Approximately 20% of undescended testes are nonpalpable and may be located within the abdominal cavity. Given the potential of these gonads for malignant transformation and infertility, it is essential to determine the presence or absence of a nonpalpable testis....

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Godbole PP,Najmaldin AS

    更新日期:2001-04-01 00:00:00

  • Extra-anatomic urinary diversion.

    abstract::In five patients with chronic intractable ureteral obstruction, a fine-bore nephrostomy tube was placed in a subcutaneous tunnel to drain the kidney without an external appliance. Good quality of life was achieved for 6 months to 2 years. When conventional intraluminal stents cannot be used, consideration should be gi...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Paterson PJ,Forrester A

    更新日期:1997-12-01 00:00:00

  • Metabolic evaluation of stone disease patients: a practical approach.

    abstract::In the last three decades, minimally invasive techniques have progressed significantly, replacing traditional open surgery as the mainstay of stone disease surgical treatment. The challenge for the next millennium remains medical prevention of calcium urolithiasis, a field where less dramatic progress has been achieve...

    journal_title:Journal of endourology

    pub_type: 杂志文章,评审


    authors: Lifshitz DA,Shalhav AL,Lingeman JE,Evan AP

    更新日期:1999-11-01 00:00:00

  • Prospective determination of ureteral orifice location: a guide for fluoroscopic ureteral stent insertion.

    abstract:PURPOSE:Ureteral stents are commonly inserted under fluoroscopic guidance. Our objective was to determine the intravesical landmarks for stent insertion by mapping the fluoroscopic location of the ureteral orifices (UOs) and bladder neck (BN) in relation to the pubic symphysis (PS). METHODS:In patients undergoing uret...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Perks AE,Schuler TD,Pace K,Honey RJ

    更新日期:2008-06-01 00:00:00

  • Robotic colposuspension: two case reports.

    abstract:BACKGROUND AND PURPOSE:Until now, open colposuspension has been the gold standard in the surgical treatment of stress urinary incontinence. However, the open procedure is associated with more complications and longer hospital stays and is hard to justify given the availability of minimally invasive alternatives. We rep...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Khan MS,Challacombe B,Rose K,Dasgupta P

    更新日期:2007-09-01 00:00:00

  • Initial Clinical Experience with Swiss LithoClast Trilogy During Percutaneous Nephrolithotomy.

    abstract:: Introduction and Objective: Current available lithotrites have clinical stone clearance rates averaging 24 to 32 mm2/minute. The objective of this study was to critically evaluate the initial experience with the Swiss LithoClast ® ...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Nottingham CU,Large T,Cobb K,Sur RL,Canvasser NE,Stoughton CL,Krambeck AE

    更新日期:2020-02-01 00:00:00

  • Long-term results of early endoscopic realignment of complete posterior urethral disruption.

    abstract:PURPOSE:To assess the long-term outcome of early endoscopic realignment (EER) of complete posterior urethral disruption. PATIENTS AND METHODS:The study included 11 consecutive patients with complete posterior urethral disruption secondary to a road accident (n = 9) or a falling impact (n = 2). EER was performed using ...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Sofer M,Mabjeesh NJ,Ben-Chaim J,Aviram G,Bar-Yosef Y,Matzkin H,Kaver I

    更新日期:2010-07-01 00:00:00

  • Doppler spectral waveform parameters at neurovascular bundle vessels in patients with prostate biopsy.

    abstract:INTRODUCTION AND OBJECTIVES:There is a need to improve prescreening determination of prostate cancer to better select patients who need biopsy. Such a strategy properly implemented, will decrease the number of negative biopsies for prostate cancer and in turn better balance the risks and morbidity for patients recommen...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Tsai YS,Jou YC,Chen CH,Chang CC,Yang WH,Lai JL,Tzai TS

    更新日期:2014-03-01 00:00:00

  • Single center comparison of laparoscopic cryoablation and CT-guided percutaneous cryoablation for renal tumors.

    abstract:BACKGROUND AND PURPOSE:Cryoablation has demonstrated therapeutic effectiveness for selected renal tumors. We compared our perioperative and short-term outcomes of laparoscopic (LAP) v percutaneous (PERC) renal cryoablation. PATIENTS AND METHODS:Thirty-four patients (18 men/16 women) underwent a LAP and 26 patients (19...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Derweesh IH,Malcolm JB,Diblasio CJ,Giem A,Rewcastle JC,Wake RW,Patterson AL,Gold R

    更新日期:2008-11-01 00:00:00

  • 7 to 10 years' follow-up of 573 patients with elevated prostate-specific antigen (>4 ng/mL) or/and suspected rectal examination: biopsies protocol and follow-up guides.

    abstract:PURPOSE:In this study, we tried to design a scheme for performing transrectal ultrasonographic (TRUS)-biopsies that would be accurate and include the optimal number of cores. PATIENTS AND METHODS:We included in this study 600 consecutive patients with suspicious findings on a per-rectum examination and/or an elevated ...

    journal_title:Journal of endourology

    pub_type: 临床试验,杂志文章


    authors: Kravchick S,Cytron S,Stepnov E,Ben-Dor D,Kravchenko Y,Peled R

    更新日期:2009-06-01 00:00:00

  • Opiate Exposure and Predictors of Increased Opiate Use After Ureteroscopy.

    abstract:: Objective: Kidney stone formers are at risk for opioid dependence. The aim of this study is to describe opiate exposure and determine predictors of prolonged opiate use among kidney stone formers after surgery. Materials and Methods: ...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Kang C,Shu X,Herrell SD,Miller NL,Hsi RS

    更新日期:2019-06-01 00:00:00

  • Safety and Efficacy of Bipolar Transurethral Resection of the Prostate vs Monopolar Transurethral Resection of Prostate in the Treatment of Moderate-Large Volume Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.

    abstract:: Aims: To compare outcomes of monopolar vs bipolar transurethral resection of the prostate (TURP) in the management of exclusively moderate-large volume prostatic hyperplasia in terms of maximum flow rate as a surrogate for clinical efficacy, duration of catheterization, ho...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Bruce A,Krishan A,Sadiq S,Ehsanullah SA,Khashaba S

    更新日期:2020-12-28 00:00:00

  • Comparison Studies of "Ultrathin Parenchyma" Resection and Sharp Dissection in Robotic Partial Nephrectomy for Renal Tumors.

    abstract:: Objective: The aim of this study was to introduce the "ultrathin parenchyma" resection in a robot-assisted partial nephrectomy (RAPN) via the retroperitoneal approach, and to assess the feasibility, security, and effectiveness of this technique. Me...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Guo J,Zhou X,Zhang C,Wang G,Fu B

    更新日期:2020-03-01 00:00:00

  • Ultrasonography-guided percutaneous nephrolithotomy in the flank position versus fluoroscopy-guided percutaneous nephrolithotomy in the prone position: a comparative study.

    abstract:BACKGROUND AND PURPOSE:Gaining access to the pyelocaliceal system in percutaneous nephrolithotomy (PCNL) is routinely performed using fluoroscopic guidance with the patient in a prone position. We compared ultrasonography-guided access for PCNL with the patient in the flank position with conventional fluoroscopy-guided...

    journal_title:Journal of endourology

    pub_type: 杂志文章,随机对照试验


    authors: Karami H,Rezaei A,Mohammadhosseini M,Javanmard B,Mazloomfard M,Lotfi B

    更新日期:2010-08-01 00:00:00

  • Comparison of holding strength of suture anchors for hepatic and renal parenchyma.

    abstract:BACKGROUND AND PURPOSE:Various laparoscopic devices have been described for suture anchoring during solidorgan parenchymal closure. Application of these devices expedites the closure of parenchymal defects and minimizes ischemia time. We compared different technologies as suture anchors for parenchymal closure. MATERI...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Ames CD,Perrone JM,Frisella AJ,Morrissey K,Landman J

    更新日期:2005-12-01 00:00:00

  • Development and initial assessment of a training program for laparoscopic radical prostatectomy. First module: the urethrovesical anastomosis.

    abstract:PURPOSE:We present our experience in the design and development of a training program in laparoscopic radical prostatectomy (LRP), and the validation of the first steps of the program by objective measurement of the attendants' skills improvement and subjective evaluation of its contents. MATERIALS AND METHODS:Our tra...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Pérez-Duarte FJ,Fernández-Tomé B,Díaz-Güemes I,Enciso S,Matos-Azevedo AM,Sánchez-Hurtado MA,Hernández L,Sánchez-Margallo FM

    更新日期:2014-07-01 00:00:00

  • Morphine-induced macrophage apoptosis modulates migration of macrophages: use of in vitro model of urinary tract infection.

    abstract:BACKGROUND:Morphine has been reported to alter immune function. Morphine-induced macrophage apoptosis has been shown to contribute to altered immune status in an opiate milieu. We studied the effect of morphine-induced macrophage apoptosis on the migration of macrophages. Because urinary tract infection (UTI) is one of...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Malik AA,Radhakrishnan N,Reddy K,Smith AD,Singhal PC

    更新日期:2002-10-01 00:00:00

  • Retroperitoneal laparoendoscopic single-site surgery in urology: initial experience.

    abstract:PURPOSE:To present our initial experience with single-port laparoscopic urologic surgery via the retroperitoneal approach using the Alexis wound retractor with flexible laparoscopic instrumentation. PATIENTS AND METHODS:Since December 2008, 14 patients have undergone single-port laparoscopic surgery for various urolog...

    journal_title:Journal of endourology

    pub_type: 杂志文章


    authors: Ryu DS,Park WJ,Oh TH

    更新日期:2009-11-01 00:00:00