Blockade of alpha-and beta -adrenergic receptors can prevent stimulation of liver ornithine decarboxylase activity by glucocorticoid or laparatomy.


:Rat liver ornithine decarboxylase induction by dexamethasone or laparatomy, which is dramatically impaired by catecholamine depletion, is not affected by alpha-and beta -adrenergic blockers administered simultaneously 1 h prior to steroid injection or operation. However, if blockade is maintained for 24 h, an effect comparable to that of catecholamine depletion is obtained. Reciprocally, the response of the decarboxylase to catecholamines is severely compromised in adrenalectomized rats. Under the same conditions, induction of tyrosine aminotransferase by dexamethasone is not significantly affected by catecholamine availability, which altogether demonstrates that rat liver ornithine decarboxylase activity is specifically governed by the interaction between glucocorticoids and catecholamines.


Astancolle S,Davalli P,Corti A




Has Abstract


1991-01-31 00:00:00














  • Regulation of methionine synthesis in Escherichia coli: effect of metJ gene product and S-adenosylmethionine on the in vitro expression of the metB, metL and metJ genes.

    abstract::The regulation of the expression of three Escherichia coli met genes, metB, which codes for cystathionine gamma-synthetase (EC, metL, which codes for aspartokinase II-homoserine dehydrogenase II (EC and metJ, which codes for the methionine regulon aporepressor, has been studied using high...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Shoeman R,Coleman T,Redfield B,Greene RC,Smith AA,Saint-Girons I,Brot N,Weissbach H

    更新日期:1985-12-17 00:00:00

  • A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain.

    abstract::Lymphokine and hematopoietic growth factors control the differentiation and proliferation of diverse cell types by binding to specific cell-surface receptors. Strikingly, the recently elucidated sequences of the interleukin-6 and erythropoietin receptors, and the interleukin-2 receptor beta-chain (p75), display a sign...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Bazan JF

    更新日期:1989-10-31 00:00:00

  • Biochemical characterization of Drosophila melanogaster acetylcholinesterase expressed by recombinant baculoviruses.

    abstract::Recombinant baculoviruses expressing full length and 3' truncated forms of c-DNA encoding the Drosophila melanogaster acetylcholinesterase (AChE) were constructed. Biochemical analyses showed that full length recombinant protein was enzymatically active and anchored to the cell membrane via a glycolipidic residue. DTT...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Chaabihi H,Fournier D,Fedon Y,Bossy JP,Ravallec M,Devauchelle G,Cérutti M

    更新日期:1994-08-30 00:00:00

  • Vitamin D fails to prevent serum starvation- or staurosporine-induced apoptosis in human and rat osteosarcoma-derived cell lines.

    abstract::Previous studies have suggested that 1,25(OH)2D3, the active form of vitamin D3, may increase the survival of bone-forming osteoblasts through an inhibition of apoptosis. On the other hand, vitamin D3 has also been shown to trigger apoptosis in human cancer cells, including osteosarcoma-derived cell lines. In the pres...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Witasp E,Gustafsson AC,Cotgreave I,Lind M,Fadeel B

    更新日期:2005-05-13 00:00:00

  • Detection of constitutive homomeric associations of the integrins Mac-1 subunits by fluorescence resonance energy transfer in living cells.

    abstract::Integrins alpha(M)beta(2) plays important role on leukocytes, such as adhesion, migration, phagocytosis, and apoptosis. It was hypothesized that homomeric associations of integrin subunits provide a driving force for integrins activation, and simultaneously inducing the formation of integrins clusters. However, experi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Fu G,Wang C,Wang GY,Chen YZ,He C,Xu ZZ

    更新日期:2006-12-29 00:00:00

  • Hyaluronan binding protein 1 (HABP1)/C1QBP/p32 is an endogenous substrate for MAP kinase and is translocated to the nucleus upon mitogenic stimulation.

    abstract::The role of hyaluronan binding protein 1 (HABP1) in cell signaling was investigated and in vitro kinase assay demonstrated that it is a substrate for MAP kinase. Phosphorylation of endogenous HABP1 was also observed following treatment of J774 cells with PMA. HABP1 was coimmunoprecipitated with activated ERK, confirmi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Majumdar M,Meenakshi J,Goswami SK,Datta K

    更新日期:2002-03-08 00:00:00

  • Identification of the metal associated with the insulin degrading enzyme.

    abstract::Insulin degrading enzyme (IDE) is a thiol-dependent metalloendoprotease that is responsible for initiation of cellular insulin degradation. However, its exact mode of action and the factors controlling it are poorly understood. Since IDE is a metal requiring enzyme, we have examined which metal(s) is(are) endogenously...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Ebrahim A,Hamel FG,Bennett RG,Duckworth WC

    更新日期:1991-12-31 00:00:00

  • Quantification by real-time PCR of developmental and adult myosin mRNA in rat muscles.

    abstract::A real-time RT-PCR assay using newly designed primers was developed to analyze developmental and adult MHC mRNA expression both in skeletal muscles and single fibers. Only 4 ng of total RNA was necessary for the analysis of the relative mRNA expression of MHC genes. Different validation steps were realized concerning ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Sanchez H,Chapot R,Banzet S,Koulmann N,Birot O,Bigard AX,Peinnequin A

    更新日期:2006-02-03 00:00:00

  • Yap1/Taz are essential for the liver development in zebrafish.

    abstract::Hippo pathway regulates cell proliferation and differentiation. Yes-associated protein (Yap) and transcriptional coactivator with PDZ-binding motif (Taz) are effectors of Hippo pathway. The function of Yap/Taz in embryonic liver development has yet to be reported. Here yap1 and taz were found expressed in liver and ot...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Yi X,Yu J,Ma C,Li L,Luo L,Li H,Ruan H,Huang H

    更新日期:2018-09-03 00:00:00

  • Histone deacetylase inhibition results in decreased macrophage CD9 expression.

    abstract::Histone deacetylase (HDAC) inhibitors have been demonstrated to regulate myeloid cell differentiation. In the present study the effects of the HDAC inhibitor trichostatin A (TSA) on the tetraspanin cell surface antigen CD9 were determined in primary murine macrophages. TSA inhibited CD9 protein and message expression ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Wang XQ,Alfaro ML,Evans GF,Zuckerman SH

    更新日期:2002-06-14 00:00:00

  • Localization of phosphoprotein PP 105 in cell lines of various species.

    abstract::The cellular location of phosphoprotein pp 105 was determined in various mouse cell lines with rabbit anti mouse pp 105 serum. Immunofluorescence was predominantly observed in the nucleoli in addition to a diffuse but weaker fluorescence of the whole nucleus. Cell surface fluorescence was obtained only with cells grow...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Pfeifle J,Anderer FA

    更新日期:1983-10-14 00:00:00

  • On the use of in vivo cargo velocity as a biophysical marker.

    abstract::Molecular motors move many intracellular cargos along microtubules. Recently, it has been hypothesized that in vivo cargo velocity can be used to determine the number of engaged motors. We use theoretical and experimental approaches to investigate these assertions, and find that this hypothesis is inconsistent with pr...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Martinez JE,Vershinin MD,Shubeita GT,Gross SP

    更新日期:2007-02-16 00:00:00

  • Ca(2+)-channels and adrenoceptors in diabetic skeletal muscle.

    abstract::The status of Ca(2+)-channels and adrenoceptors in the hind leg skeletal muscle was examined in rats 8 weeks after inducing diabetes by an intravenous injection of streptozotocin (65 mg/kg). Scatchard plot analysis of the data on specific binding of 3H-nitrendipine with crude membranes from diabetic muscle revealed an...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Lee SL,Dhalla NS

    更新日期:1992-04-15 00:00:00

  • Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR.

    abstract::During screening for the flavonoid chemosensitizers, it was found that 5,7,3',4',5'-pentamethoxyflavone (PMF) was equipotent to verapamil in vitro with respect to the chemosensitizing effect. PMF appears to have a chemosensitizing effect not only by increasing the intracellular accumulation of the drugs without compet...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Choi CH,Kim JH,Kim SH

    更新日期:2004-07-30 00:00:00

  • In vitro transcription termination activity of the Drosophila mitochondrial DNA-binding protein DmTTF.

    abstract::DmTTF is a Drosophila melanogaster mitochondrial DNA-binding protein which binds specifically to two homologous non-coding sequences located at the 3' ends of blocks of genes encoded on opposite strands. In order to test whether this protein acts as transcription termination factor, we assayed the capacity of DmTTF to...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Roberti M,Fernandez-Silva P,Polosa PL,Fernandez-Vizarra E,Bruni F,Deceglie S,Montoya J,Gadaleta MN,Cantatore P

    更新日期:2005-05-27 00:00:00

  • Tumor promoting phorbol diesters: substrates for diacylglycerol lipase.

    abstract::Enzyme activity in rat serum was examined utilizing the potent tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and various glycerolipids as substrates. The serum activity was specific for hydrolysis of the long chain tetradecanoate moiety of TPA, hydrolyzed mono- and diacylglycerols, but was not effective ag...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Cabot MC

    更新日期:1984-08-30 00:00:00

  • IL-1 beta-dependent regulation of C/EBP delta transcriptional activity.

    abstract::We have previously shown that the transcription factor C/EBP delta is involved in the intestinal inflammatory response. C/EBP delta regulates several inflammatory response genes, such as haptoglobin, in the rat intestinal epithelial cell line IEC-6 in response to IL-1. However, the different C/EBP delta domains involv...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Svotelis A,Doyon G,Bernatchez G,Désilets A,Rivard N,Asselin C

    更新日期:2005-03-11 00:00:00

  • Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes.

    abstract::Multi electrode arrays (MEAs) are increasingly used to detect external field potentials in electrically active cells. Recently, in combination with cardiomyocytes derived from human (induced) pluripotent stem cells they have started to become a preferred tool to examine newly developed drugs for potential cardiac toxi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Tertoolen LGJ,Braam SR,van Meer BJ,Passier R,Mummery CL

    更新日期:2018-03-18 00:00:00

  • Synthesis and characterization of a d(ApG) platinated nonanucleotide duplex.

    abstract::The nonamer 5'd(CTCAGCCTC) 3' 1 has been reacted with cis-diamminediaquaplatinum(II) in water at pH 4.2. The major reaction product was shown by enzymatic digestion and 1H NMR to be the d(ApG)cis-Pt(NH3)2 chelate [cis-Pt(NH3)2[d(CTCAGCCTC)-N7(4),N7(5)]] 1-Pt. When mixed with its complementary strand 2, 1-Pt forms a B ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Fouchet MH,Gauthier C,Guittet E,Girault JP,Igolen J,Chottard JC

    更新日期:1992-01-31 00:00:00

  • Activity of an enzyme immobilized on superparamagnetic particles in a rotational magnetic field.

    abstract::We immobilize alpha-amylase extracted from Bacillus Iicheniformis on the surfaces of superparamagnetic particles and investigate the effect of a rotational magnetic field on the enzyme's activity. We find that the activity of the enzyme molecules immobilized on superparamagnetic particles increases in the rotational m...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Mizuki T,Watanabe N,Nagaoka Y,Fukushima T,Morimoto H,Usami R,Maekawa T

    更新日期:2010-03-19 00:00:00

  • Peroxynitrite-mediated oxidation of ferrous carbonylated myoglobin is limited by carbon monoxide dissociation.

    abstract::Peroxynitrite-mediated oxidation of ferrous nitrosylated myoglobin (Mb(II)-NO) involves the transient ferric nitrosylated species (Mb(III)-NO), followed by ()NO dissociation and formation of ferric myoglobin (Mb(III)). In contrast, peroxynitrite-mediated oxidation of ferrous oxygenated myoglobin (Mb(II)-O2) involves t...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Ascenzi P,Ciaccio C,Coletta M

    更新日期:2007-11-30 00:00:00

  • Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity.

    abstract::Hypoxia is generally detected in central regions of solid tumors and regulates a variety of transcription factors including hypoxia-inducible factor-1 (HIF-1). HIF-1 plays a pivotal role in cellular response to low oxygen concentration, such as angiogenesis in tumor. Here, we found that a histone deacetylase (HDAC) in...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Mie Lee Y,Kim SH,Kim HS,Jin Son M,Nakajima H,Jeong Kwon H,Kim KW

    更新日期:2003-01-03 00:00:00

  • Trafficking of astrocytic vesicles in hippocampal slices.

    abstract::The increasingly appreciated role of astrocytes in neurophysiology dictates a thorough understanding of the mechanisms underlying the communication between astrocytes and neurons. In particular, the uptake and release of signaling substances into/from astrocytes is considered as crucial. The release of different gliot...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Potokar M,Kreft M,Lee SY,Takano H,Haydon PG,Zorec R

    更新日期:2009-12-25 00:00:00

  • Down-regulation of prolactin receptors in the liver, mammary gland and kidney of female virgin rat, infused with ovine prolactin or human growth hormone.

    abstract::Down regulation of prolactin (PRL) receptors resulting from i.v. infusion of oPRL or human growth hormone (hGH) into female virgin rats was demonstrated. A decrease of over 85% in the number of free receptors was achieved within 15 - 30 min using infusion of oPRL or hGH at 25 micrograms/h and remained at this level un...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Barash I,Madar Z,Gertler A

    更新日期:1983-10-31 00:00:00

  • Alteration by v-Ki-ras in NaF, cholera toxin and forskolin-induced adenylate cyclase activation in NIH/3T3 fibroblast cells.

    abstract::It has been suggested that ras proteins are involved in the transmembrane signaling mechanism and they share structural features with GTP-binding proteins. To identify the role of ras oncogene and it's products in the coupling mechanisms of GTP-binding proteins to adenylate cyclase, we examined effect of NaF, cholera ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Konishi-Imamura L,Noda M,Nomura Y

    更新日期:1987-07-15 00:00:00

  • Protein kinase C binding to isolated nuclei and its activation by a Ca2+/phospholipid-independent mechanism.

    abstract::The direct interaction of protein kinase C with the nucleus was examined utilizing endogenous protein phosphorylation and [3H]PDBu binding to detect the enzyme. Rat brain nuclei were relatively rich in phorbol ester receptors whereas liver nuclei contained less than 10% of their brain counterpart. Purified protein kin...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Misra UK,Sahyoun N

    更新日期:1987-06-15 00:00:00

  • Generation of cloned calves and transgenic chimeric embryos from bovine embryonic stem-like cells.

    abstract::Bovine embryonic stem-like cells (ES-like cells) appear to maintain a normal diploid karyotype indefinitely during culture in vitro and to express marker proteins that are characteristic of ES cells from mice, namely, alkaline phosphatase (AP), stage-specific embryonic antigen-1 (SSEA-1), STAT-3, and Oct 4. After prol...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Saito S,Sawai K,Ugai H,Moriyasu S,Minamihashi A,Yamamoto Y,Hirayama H,Kageyama S,Pan J,Murata T,Kobayashi Y,Obata Y,Yokoyama KK

    更新日期:2003-09-12 00:00:00

  • Kinetic studies of the electron exchange reaction between the octaheme cytochrome c3 (Mr 26000) and the hydrogenase from Desulfovibrio desulfuricans Norway.

    abstract::The octaheme cytochrome c3 (Mr 26000) from Desulfovibrio desulfuricans Norway was studied using cyclic voltammetry at the pyrolytic graphite electrode. The kinetics of reduction of the octaheme cytochrome c3 (Mr 26000) from D. desulfuricans Norway by the Ni-Fe-Se hydrogenase purified from the same organism was investi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Haladjian J,Bianco P,Guerlesquin F,Bruschi M

    更新日期:1991-08-30 00:00:00

  • Suppression of HIF-1α accumulation by betulinic acid through proteasome activation in hypoxic cervical cancer.

    abstract::Betulinic acid (BA) exhibits various biological activities such as anti-bacterial, anti-inflammatory, anti-human papilloma virus (HPV), and anti-cancer activities. HPV infection is associated with a high risk of cervical cancer, which is the leading cause of deaths among women worldwide. Therefore, BA is an attractive...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Kim HJ,Cho HS,Ban HS,Nakamura H

    更新日期:2020-03-12 00:00:00

  • Proteolipidic vectors for gene transfer to the lung.

    abstract::In order to develop improved synthetic gene transfer vectors, we have synthesized bifunctional peptides composed of a DNA binding peptide (P2) and ligand peptides selected by the phage display technique on tracheal epithelial cells. We have evaluated the capacity of these peptides to enhance the gene transfer efficien...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章


    authors: Vaysse L,Guillaume C,Burgelin I,Gorry P,Férec C,Arveiler B

    更新日期:2002-02-08 00:00:00