Intrahepatic cholangiocarcinoma with lymph node metastasis successfully treated by immunotherapy with CD3-activated T cells and dendritic cells after surgery: report of a case.

Abstract:

:Intrahepatic cholangiocarcinoma (ICC) with lymph node (LN) metastasis is generally associated with a poor prognosis. However, we treated ICC with LN metastasis successfully by surgery and postoperative immunotherapy in a 59-year-old woman. The immunotherapy consisted of CD3-activated T cells and tumor lysate- or peptide-pulsed dendritic cells. Pathological examination confirmed a diagnosis of moderately differentiated adenocarcinoma with LN metastasis and portal vein invasion. The patient has been alive without recurrence for 3 years 6 months since her operation.

journal_name

Surg Today

journal_title

Surgery today

authors

Higuchi R,Yamamoto M,Hatori T,Shimizu K,Imai K,Takasaki K

doi

10.1007/s00595-006-3201-1

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

559-62

issue

6

eissn

0941-1291

issn

1436-2813

journal_volume

36

pub_type

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