Intrahepatic cholangiocarcinoma with lymph node metastasis successfully treated by immunotherapy with CD3-activated T cells and dendritic cells after surgery: report of a case.


:Intrahepatic cholangiocarcinoma (ICC) with lymph node (LN) metastasis is generally associated with a poor prognosis. However, we treated ICC with LN metastasis successfully by surgery and postoperative immunotherapy in a 59-year-old woman. The immunotherapy consisted of CD3-activated T cells and tumor lysate- or peptide-pulsed dendritic cells. Pathological examination confirmed a diagnosis of moderately differentiated adenocarcinoma with LN metastasis and portal vein invasion. The patient has been alive without recurrence for 3 years 6 months since her operation.


Surg Today


Surgery today


Higuchi R,Yamamoto M,Hatori T,Shimizu K,Imai K,Takasaki K




Has Abstract


2006-01-01 00:00:00












  • Multiple jejunal diverticulitis with perforation in a patient with systemic lupus erythematosus: report of a case.

    abstract::A 70-year-old man with systemic lupus erythematosus (SLE) was brought to our Emergency Department after the sudden onset of acute and severe abdominal pain. Physical examination revealed a tender and distended abdomen with guarding and rebound tenderness in the periumbilical region and the left upper quadrant. A plain...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Yağmur Y,Aldemir M,Büyükbayram H,Taçyildiz I

    更新日期:2004-01-01 00:00:00

  • Impact of esophageal flexion level on the surgical outcome in patients with sigmoid esophageal achalasia.

    abstract:PURPOSE:Esophageal achalasia can be roughly divided into non-sigmoid and sigmoid types. Laparoscopic surgery has been reported to be less than optimally effective for sigmoid type. The aim of this study was to examine the impact of the esophageal flexion level on the clinical condition and surgical outcomes of patients...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Tsuboi K,Omura N,Yano F,Hoshino M,Yamamoto SR,Akimoto S,Masuda T,Kashiwagi H,Yanaga K

    更新日期:2017-11-01 00:00:00

  • Pregnancy after undergoing the Fontan procedure for a double outlet right ventricle: report of a case.

    abstract::We describe a 25-year-old woman who had a successful pregnancy after the repair of a double outlet right ventricle using the Fontan procedure. Although the number of reported patients is small, women who have good hemodynamic results after the operation can apparently tolerate both pregnancy and delivery. ...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Ito M,Takagi N,Sugimoto S,Oosawa H,Abe T

    更新日期:2002-01-01 00:00:00

  • The development of a small bowel volvulus in the early postoperative period following a distal gastrectomy: report of a case.

    abstract::A 51-year-old Japanese man who underwent a standard distal gastrectomy for cancer of the stomach developed abdominal pain when oral intake was commenced on the 6th postoperative day after an uneventful postoperative course. Complete obstruction of the jejunum led to a sudden deterioration in his general condition and ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Sakamoto T,Miyata M,Nakamuro M,Izukura M,Kamiike W,Matsuda H

    更新日期:1994-01-01 00:00:00

  • Postprandial hyperglycemia after a gastrectomy and the prediabetic state: a comparison between a distal and total gastrectomy.

    abstract:PURPOSE:Postprandial hyperglycemia is recognized as an important risk factor for developing type 2 diabetes; it is also common in patients after a gastrectomy and is likely to become exacerbated after a total gastrectomy rather than after a distal gastrectomy. In this study, we investigated the glucose and insulin resp...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Yamamoto H,Tsuchihashi H,Akabori H,Naitoh H,Maegawa H,Tani T

    更新日期:2008-01-01 00:00:00

  • Surgical repair of a concealed aortocaval fistula associated with an abdominal aortic aneurysm: report of two cases.

    abstract::Two cases of a concealed aortocaval fistula (ACF) associated with an abdominal aortic aneurysm (AAA) are presented herein. ACF is a rare complication of AAA and only a few cases have so far shown the triad of symptoms, including congestive heart failure, a continuous abdominal bruit, and a pulsating abdominal mass. So...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Takazawa A,Sakahashi H,Toyama A

    更新日期:2001-01-01 00:00:00

  • Effect of indocyanine green fluorescence angiography on preventing anastomotic leakage after colorectal surgery: a meta-analysis.

    abstract::Anastomotic leakage (AL) is a serious but not uncommon complication after colorectal surgery. We conducted this study to evaluate the effect of routine indocyanine green fluorescence angiography (ICG-FA) on reducing the AL rate after colorectal surgery. We identified all research articles about colorectal surgery usin...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Zhang W,Che X

    更新日期:2021-01-11 00:00:00

  • Four stay-sutures method: a simplified hand-sewn purse-string suture in laparoscopic circular-stapled esophagojejunostomy.

    abstract::Laparoscopic esophagojejunostomy is a challenging procedure because of its technical difficulty. We herein report a new method involving circular-stapled anastomosis using a hand-sewn suture with four stay-sutures and evaluate its outcomes. Esophagojejunostomy using this method was performed in 36 consecutive patients...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Sano A,Ojima H,Ogawa A,Ogata K,Saito K,Fukasawa T,Sohda M,Fukai Y,Mochida Y,Fukuchi M,Naitoh H,Saeki H,Shirabe K

    更新日期:2020-03-01 00:00:00

  • Ultrasound-guided infraclavicular axillary vein puncture is effective to avoid pinch-off syndrome: a long-term follow-up study.

    abstract:PURPOSE:Pinch-off syndrome (POS) is a serious complication encountered during the long-term management of totally implantable access ports (TIAPs). The aim of this study was to examine the effect of ultrasound-guided infraclavicular axillary vein puncture to avoid POS in patients with long-term use of a TIAP. METHODS:...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Osawa H,Hasegawa J,Yamakawa K,Matsunami N,Mikata S,Shimizu J,Kim YK,Morishima H,Hirota M,Souma Y,Kim HM,Sawada G,Nezu R

    更新日期:2013-07-01 00:00:00

  • Intestinal bleeding from arteriovenous malformations of the small bowel in a patient with Cowden syndrome: report of a case.

    abstract::This report presents the case of a patient with Cowden syndrome who had arteriovenous malformations (AVMs) at the jejunum and the ileum and experienced intestinal bleeding. A 54-year-old Japanese male presented with general fatigue and melena. Endoscopic examinations showed gastrointestinal polyposis from the esophagu...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Nakayama Y,Segawa J,Sujita K,Minagawa N,Torigoe T,Hisaoka M,Yamaguchi K

    更新日期:2013-05-01 00:00:00

  • An icteric type hepatocellular carcinoma with no detectable tumor in the liver: report of a case.

    abstract::A 70-year-old man was admitted to our hospital with obstructive jaundice. Computed tomography revealed a tumor in the left intrahepatic bile duct extending to the common bile duct without any significant lesions in the liver. Cholangiography showed a filling defect due to an intraductal tumor. Cytology of the bile jui...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Makino T,Nakamori S,Kashiwazaki M,Masuda N,Ikenaga M,Hirao M,Fujitani K,Mishima H,Sawamura T,Takeda M,Mano M,Tsujinaka T

    更新日期:2006-01-01 00:00:00

  • The appearance of a normal appendix on barium enema examination does not rule out a diagnosis of chronic appendicitis: report of a case and review of the literature.

    abstract::We report herein the rare case of a 15-year-old girl with chronic appendicitis in whom the appendix was clearly depicted by a barium enema (BE) examination. The patient presented with a 4-month history of diffuse abdominal pain and tenderness in the lower abdomen. Neither computed tomography nor ultrasonography showed...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Okamoto T,Utsunomiya T,Inutsuka S,Sakaguchi T,Notsuka T,Maeda T,Sugimachi K

    更新日期:1997-01-01 00:00:00

  • Multiple cystic pulmonary chondroid hamartomas colonized by Aspergillus species: report of a case.

    abstract::Pulmonary hamartoma is the most common benign neoplasm of the lung, but the cystic form is very rare. This report presents the case of a 31-year-old woman with two cystic pulmonary lesions. She was radiologically and clinically diagnosed to have multiple ruptured hydatid cysts, and underwent a thoracotomy. The patholo...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ozyurtkan MO,Dağli AF,Cakmak M,Balci AE

    更新日期:2011-04-01 00:00:00

  • Effects of antibiotics and Saccharomyces boulardii on bacterial translocation in burn injury.

    abstract:PURPOSE:To investigate the effects of antibiotics and the probiotic, Saccharomyces boulardii, on indigenous microflora and bacterial translocation (BT) in burned rats. METHODS:Twenty-three male albino rats were divided into a sham burn group (group 1, n = 7) exposed to 21 degrees C water, a burn + antibiotic group (gr...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Herek O,Kara IG,Kaleli I

    更新日期:2004-01-01 00:00:00

  • Effect of thrombopoietin on platelet counts and liver regeneration after partial hepatectomy in a rat model.

    abstract:PURPOSE:We investigated the effects of thrombopoietin (TPO) on platelet counts and liver regeneration after partial hepatectomy in rats. METHODS:We performed 70% partial hepatectomy on 60 rats given either TPO or a vehicle (controls). The rats were killed 6 h, 24 h, 72 h, or 168 h after the procedure, and we examined ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Shimabukuro R,Kawanaka H,Tomikawa M,Akahoshi T,Konishi K,Yoshida D,Anegawa G,Uehara H,Hashimoto N,Hashizume M,Maehara Y

    更新日期:2009-01-01 00:00:00

  • A clinicopathological investigation on superficial early invasive carcinomas of the colon and rectum.

    abstract::Due to recent advances in endoscopic surgical techniques, it has now become possible to perform endoscopic resection of most early invasive carcinomas of the colon and rectum (EIC) even if the lesions have invaded the submucosa. In the present study, we investigated the microscopic characteristics of superficial EIC c...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Okabe S,Arai T,Maruyama S,Murase N,Tsubaki M,Endo M

    更新日期:1998-01-01 00:00:00

  • The effects of recombinant tissue-type plasminogen activator (rt-PA) on canine cadaver lung transplantation.

    abstract::The intrapulmonary thrombi that form after the cessation of circulation are thought to be one of the major causes of graft function failure. We evaluated the effect of recombinant tissue-type plasminogen activator (rt-PA) in a canine cadaver lung transplant model. Donor dogs were killed by the intravenous administrati...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Akasaka S,Nishi H,Aoe M,Date H,Andou A,Shimizu N

    更新日期:1999-01-01 00:00:00

  • Beneficial effects of administering intraportal prostaglandin E1 postoperatively to hepatectomy patients with massive intraoperative blood loss.

    abstract::Massive intraoperative blood loss is a major cause of complications following hepatectomy. To evaluate the efficacy of intraportal prostaglandin E1 (PGE1) for preventing liver deterioration in hepatectomy patients with an intraoperative blood loss of over 2000 ml, a retrospective analysis was conducted on 10 patients ...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章


    authors: Katsuramaki T,Mukaiya M,Yamashiro K,Kimura H,Denno R,Hirata K

    更新日期:1996-01-01 00:00:00

  • Water-clear cell parathyroid adenoma causing primary hyperparathyroidism in a patient with neurofibromatosis type 1: report of a case.

    abstract::Water-clear cell parathyroid adenoma is an exceedingly rare tumor, composed exclusively of tumor cells with abundant foamy cytoplasm. A combination of hyperparathyroidism and neurofibromatosis type 1 (NF1) is also a rare phenomenon. We report an 18-year-old woman with primary hyperparathyroidism caused by water-clear ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Kodama H,Iihara M,Okamoto T,Obara T

    更新日期:2007-01-01 00:00:00

  • Surgical treatment of an enormous aneurysmal portahepatic venous fistula: report of a case.

    abstract::We report herein the case of a 20-year-old woman in whom an enormous aneurysmal portahepatic venous fistula was found. The portal aneurysm developed in the anterior inferior segment of the right hepatic lobe, and communicated with the right portal vein and the right hepatic vein. Due to the enormous size of the shunt,...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Miyauchi A,Okada S,Hashimoto T,Wakabayashi H,Maeba T,Tanaka S,Hayashi H

    更新日期:1995-01-01 00:00:00

  • Successful treatment of intraoperative heart failure caused by ampulla cardiomyopathy by intra-aortic balloon pumping and percutaneous cardiopulmonary support: report of a case.

    abstract::An 82-year-old woman underwent total gastrectomy for advanced gastric cancer with invasion to the lower esophagus. Her blood pressure dropped alarmingly during the operation, which was performed via the transabdominal and left-side transthoracic approach. Using echocardiography, we diagnosed intraoperative-onset rever...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Yabuuchi S,Miura K,Shiiba K,Shibata C,Ishii S,Mizoi T,Ejima Y,Horinouchi T,Iwabuchi K,Oda K,Unno M,Morita R,Nagaya K,Nitta Y,Matsuno S,Sasaki I

    更新日期:2005-01-01 00:00:00

  • The use of an omental pedicle graft to prevent small-bowel obstruction after restorative proctocolectomy.

    abstract::Small-bowel obstruction remains one of the most frequent complications after restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA). Of particular concern is small-bowel adhesion to the pelvic dead space that causes afferent limb obstruction, sometimes necessitating laparotomy. In this report, we describ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Nakagoe T,Sawai T,Tuji T,Nanashima A,Yamaguchi H,Yasutake T,Ayabe H

    更新日期:1999-01-01 00:00:00

  • Giant hemorrhagic adrenal pseudocyst in a primiparous pregnancy: report of a case.

    abstract::Adrenal cysts are rare and are usually discovered incidentally during diagnostic imaging, surgery, or autopsy. Most cystic lesions of the adrenal gland are nonfunctioning and become symptomatic when complicated by rupture, hemorrhage, or infection. A 40-year-old woman presented with a history of gradual-onset pain in ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Karaman K,Teke Z,Dalgic T,Ulas M,Seven MC,Zulfikaroglu E,Sakaogullari Z,Bostanci EB

    更新日期:2011-01-01 00:00:00

  • A nomogram for predicting rectovaginal fistula after low anterior resection for rectal cancer.

    abstract:PURPOSE:Rectovaginal fistula (RVF) is a complicated and troublesome complication of low anterior resection (LAR) for rectal cancer. We aimed to investigate the risk factors for post-LAR RVF and develop a predictive nomogram. METHODS:We performed a retrospective analysis of 821 female patients with rectal cancer who un...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Huang MJ,Ye DX,Lin Y,Lu XR,Lin HM,Chi P,Huang Y

    更新日期:2020-10-01 00:00:00

  • Pancreaticoduodenectomy in portal annular pancreas: report of a case.

    abstract::Portal annular pancreas (PAP) is a rare anatomical anomaly in which the pancreatic parenchyma surrounds the superior mesenteric vein and portal vein (PV) annularly. This anomaly requires careful consideration in pancreatic resection. A case is presented and the technical issues are discussed. A 61-year-old female was ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Kobayashi S,Honda G,Kurata M,Okuda Y,Tsuruta K

    更新日期:2013-08-01 00:00:00

  • Side-to-end anastomosis in a colostomy for acute malignant large-bowel obstruction: side-to-end anastomosis with a colostomy (STEC procedure).

    abstract::This report describes the use of side-to-end anastomosis in a colostomy for an acute malignant large-bowel obstruction. A 59-year-old man presented with a colonic obstruction due to advanced descending colon cancer. The preoperative imaging studies revealed a complete obstruction of the descending colon at the site of...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Fukami Y,Terasaki M,Sakaguchi K,Murata T,Ohkubo M,Nishimae K

    更新日期:2009-01-01 00:00:00

  • Solitary pancreatic metastasis from renal cell carcinoma concomitant with early gastric cancer 17 years after nephrectomy: report of a case.

    abstract::The pancreas is an uncommon site for metastasis from renal cell carcinoma. We report the case of a 70-year-old man in whom a solitary pancreatic metastasis from renal cell carcinoma, found 17 years after nephrectomy, was successfully resected, combined with gastrectomy for early gastric cancer. We also discuss the rel...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Uemura T,Kurita A,Nishimura R,Ishizaki M,Takashima S

    更新日期:2003-01-01 00:00:00

  • Primary localized amyloidosis of the small intestine presenting as an intestinal pseudo-obstruction: report of a case.

    abstract::A 47-year-old man with primary amyloidosis confined to the small intestine is reported. Thickening of the folds and multiple polypoid protrusions were found in the duodenum by upper gastrointestinal endoscopy. Because the patient presented with a persistent intestinal pseudo-obstruction, partial jejunectomy was perfor...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Deguchi M,Shiraki K,Okano H,Yamanaka T,Ito N,Takase K,Nakano T

    更新日期:2001-01-01 00:00:00

  • Spinal cord injury following aortic arch replacement.

    abstract:PURPOSE:Postoperative spinal cord injury is a devastating complication after aortic arch replacement. The purpose of this study was to determine the predictors of this complication. METHODS:A group of 254 consecutive patients undergoing aortic arch replacement via median sternotomy, with (n = 78) or without (n = 176) ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Tokuda Y,Fujimoto K,Narita Y,Mutsuga M,Terazawa S,Ito H,Matsumura Y,Uchida W,Munakata H,Ashida S,Ono T,Nishi T,Yano D,Ishida S,Kuwabara F,Akita T,Usui A

    更新日期:2020-02-01 00:00:00

  • Portal imaging by intravenous three-dimensional computed tomography after pancreaticoduodenectomy: a report of four cases.

    abstract::By employing three-dimensional computed tomography (CT) for portography, we analyzed the portal vein changes during the initial stage after a pancreaticoduodenectomy (PD), which seemed to affect postoperative complications. Four patients underwent PD without portal vein reconstruction with a standard radical lymph nod...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ryo H,Yoshida K,Akiyama K,Yamashita Y,Momose J,Monya K,Ido K

    更新日期:1998-01-01 00:00:00