Pulmonary embolism as a cause of death in patients with heart disease: an autopsy study.

Abstract:

STUDY OBJECTIVE:To establish the prevalence of pulmonary embolism (PE) in autopsy material at a tertiary cardiac referral center and its importance as a cause of death in patients with heart disease (HD). DESIGN:Case series. SETTING:National Heart Institute, Mexico City. PATIENTS:One thousand thirty-two patients who died at our institution from 1985 to 1994 in whom an autopsy study was performed. MEASUREMENTS AND RESULTS:Of the 1,032 autopsies reviewed, 231 cases (24.4%) of PE were found; 100 of these patients had a diagnosis of massive PE. Massive PE (obstruction of either of the main pulmonary arteries or more than two lobar arteries) was found to be the third cause of death in this HD population. By age-group distribution, the global prevalence of massive events was higher in patients < 10 years old. Clinical suspicion (premortem) was raised in only 18% of the cases. CONCLUSIONS:PE was a frequent cause of morbidity and mortality in patients with HD who underwent autopsies. The incidence of massive PE was high in children.

journal_name

Chest

journal_title

Chest

authors

Pulido T,Aranda A,Zevallos MA,Bautista E,Martínez-Guerra ML,Santos LE,Sandoval J

doi

10.1378/chest.129.5.1282

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

1282-7

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)50708-3

journal_volume

129

pub_type

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