Abstract:
:Longitudinal data of neurocognitive functions and quality of life (QOL) were obtained for a cohort of 25 patients followed before transplant and through the first year after haematopoietic stem cell transplantation (SCT). A battery of neuropsychological tests and two self-report questionnaires were used to assess neurocognitive functions, QOL and psychological functioning. In comparison to normative data, up to one-fourth of the patients experienced impaired functioning on several cognitive domains before SCT. Random regression modelling revealed a slight improvement in the mean group scores of memory tasks over time, especially for younger patients. Impairment in neurocognitive functions was positively related to depression and anger at baseline, and to the emotional functioning scale at follow-up. These preliminary results emphasize the significance of a pre-treatment assessment and the need of a large baseline sample in future longitudinal studies to overcome the expected dropout rate of more than 50%.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Harder H,Duivenvoorden HJ,van Gool AR,Cornelissen JJ,van den Bent MJdoi
10.1080/13803390490918147subject
Has Abstractpub_date
2006-04-01 00:00:00pages
283-93issue
3eissn
1380-3395issn
1744-411Xpii
GL113T3884N3TM46journal_volume
28pub_type
临床试验,杂志文章abstract::The standardization sample from the WMS-III (weighted N = 1250) (The Psychological Corporation, 1997; Tulsky & Ledbetter, 2000), which varied in age from 16 to 89, was used to determine whether storage of verbal and spatial information was affected by normal aging. A previous study with the same sample using an analys...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390490496678
更新日期:2004-06-01 00:00:00
abstract::Less efficient glucose regulation, the ability to metabolize glucose, has been associated with poorer cognitive performances in older individuals not meeting criteria for type 2 diabetes ( Messier, Tsiakas, Gagnon, & Desrochers, 2010 ). Yet, the influence of glucose regulation on attentional functions, which are sensi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.589372
更新日期:2011-11-01 00:00:00
abstract::Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of severe amnesia without concomitant focal neurological symptoms. This meta-analysis of the cognitive characteristics of TGA addressed two main issues. First, we examined the hypothesis that the acute phase of TGA is associated wi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,meta分析
doi:10.1080/13803390801955193
更新日期:2009-01-01 00:00:00
abstract::The performance of 11 Alzheimer's (DAT) and 8 anomic aphasic stroke patients is contrasted with that of 32 normal elderly subjects on both the Boston Naming Test (BNT) and the Controlled Oral Word Association Test (COW), a letter-category verbal-fluency test. While both tests require phonological processing, only the ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639008401004
更新日期:1990-08-01 00:00:00
abstract::Time disorientation is a common feature of anterograde memory disorder caused by brain illness. This observation suggests that the subjective time constructions used to organize events are strongly dependent upon memory storage processes. This study evaluated one prominent cognitive theory of time estimation from the ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638908400927
更新日期:1989-10-01 00:00:00
abstract::The aim of the present study was to evaluate selective visual attention in subjects affected by Alzheimer's Disease (AD), by means of a computerized spatial exploration test that adopts a Touch Screen (TS) interface, which has already proved able to characterize alternative strategies in performing search tasks. We as...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390490520427
更新日期:2005-05-01 00:00:00
abstract:INTRODUCTION:This study investigated proactive and retroactive interference effects between the Wechsler Memory Scale-Fourth Edition (WMS-IV) using the flexible approach, and the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). METHOD:One hundred and eighty nonclinical participants were assigned to a four (...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1119253
更新日期:2016-01-01 00:00:00
abstract::The goal of the current study was to evaluate presetting, response inhibition, set shifting, and a priori planning in autism: abilities that can be lumped together under the term cognitive flexibility. Cognitive flexibility is an aspect of executive functioning, which in turn is mediated by the prefrontal cortical lob...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390601186668
更新日期:2008-01-01 00:00:00
abstract::This study assessed the acquisition of conditional-associations using neutral and individually threatening nouns in 16 females with anorexia nervosa (AN), 16 females with bulimia nervosa (BN) and 16 normal controls (NC). Groups did not differ in terms of age, sex, handedness, depression, intelligence, verbal memory an...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.24.2.176.990
更新日期:2002-04-01 00:00:00
abstract::We examined 6 patients with robust visual neglect following right hemisphere damage. All of them had signs of auditory neglect as documented by the inferior identification of syllables delivered through a loudspeaker on the left side. When the same stimuli on the left were administered in the presence of a fictitious ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639508405121
更新日期:1995-04-01 00:00:00
abstract::Several neurocognitive studies have indicated that children with attention-deficit/hyperactivity disorder (ADHD) exhibit cognitive deficits in perceptual timing functions; however, only a few electroencephalographic studies have investigated their time reproduction abilities. In the present research, 15 children with ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2017.1406897
更新日期:2018-09-01 00:00:00
abstract::Both amnestic and nonamnestic deficits have been observed in patients with mild cognitive impairment (MCI). Most studies have focused on impairment on single cognitive tests rather than amalgamation of the results of several measures to arrive at a composite impairment index. In this investigation, we examined 20 MCI ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390600681206
更新日期:2007-04-01 00:00:00
abstract::Two studies addressed issues concerning the validity of the Presidents Test. The results of Study 1 substantiated that generalized impairment for recent presidents occurs frequently in the context of multifocal and diffuse cerebral disease. Performances of normal elderly (n = 31) on all four Presidents subtests were s...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639008400967
更新日期:1990-03-01 00:00:00
abstract::Previous neuropsychological research suggests that psychometrically defined subclinical obsessive-compulsive (OC) individuals perform worse than non-OC controls on specific tests of executive functioning. This study aimed to extend these findings by comparing the performance of 25 subclinical OC and 28 non-OC control ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.6.830.16477
更新日期:2003-09-01 00:00:00
abstract::This investigation examined the effects of HIV-1 infection on speeded complex cognitive processing in a group of HIV-negative (n = 666), HIV-positive symptomatic (n = 156), and HIV-positive asymptomatic (n = 623) participants while controlling for the effects of slowed motor functioning, peripheral neuropathy, and sev...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,多中心研究
doi:10.1076/jcen.20.1.60.1489
更新日期:1998-02-01 00:00:00
abstract::Fifty-one children who has sustained head injuries were divided into mildly, moderately and severely injured groups according to neurological criteria. The groups were matched for age, sex, and injury-test interval. Approximately 1 year after their injuries, patients were tested on speeded and nonspeeded measures of m...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638508401241
更新日期:1985-02-01 00:00:00
abstract::Past research has found links among cerebrovascular risk factors (CVRFs), depression, and cognition in older adults. This study investigated how well baseline cerebrovascular burden and depression predicted verbal fluency three and six months later. Participants were 139 medical rehabilitation patients, age 60 and abo...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390590949322
更新日期:2006-05-01 00:00:00
abstract::This pilot study characterizes memory functioning of 11 men with occupational chronic solvent encephalopathy (CSE). Pattern (PRM) and spatial recognition (SRM), spatial span (SSP), spatial working memory (SWM), and paired associate learning (PAL) from Cambridge Neuropsychological Test Automated Battery were performed ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390500477515
更新日期:2006-11-01 00:00:00
abstract::The performance of a group of 60 severely closed-head-injured patients in the subacute stage of recovery on a series of tests addressing focused, divided, and sustained attention, and supervisory attentional control was compared to the performance of a matched group of 60 healthy controls. Patients performed significa...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1080/01688639608408298
更新日期:1996-10-01 00:00:00
abstract::The effects of two memory-impairing drugs, ethanol and triazolam, on proactive interference (PI) in memory were studied. Following ingestion of either one of these drugs or a placebo, subjects studied an A-B list (e.g., BEE-WASP) of paired associates, followed by an A-C list (e.g., BEE-HONEY) on the interference trial...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1080/01688639708403755
更新日期:1997-10-01 00:00:00
abstract:INTRODUCTION:Many studies have shown altered neuropsychological functioning of children with epilepsy even in the absence of intellectual disability, with notable concerns for both patients and their families. Although studies have described the cognitive profiles associated with specific epilepsy syndromes, there is i...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1076380
更新日期:2015-01-01 00:00:00
abstract::Previous studies have attributed poor memory for words after left temporal lobectomy (LTL) to a verbal memory deficit and poor memory for abstract designs after right temporal lobectomy (RTL) to a difficulty in remembering nonverbal/visual stimuli. In this investigation, the contribution of stimulus novelty to lateral...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.1.36.13625
更新日期:2003-02-01 00:00:00
abstract::Proficient, nonnative English-speaking neurosurgery candidates are assessed for language function in English. In order to understand whether it is necessary to also assess native-language function, we examined the influence of native language on the bilingual language network of early, proficient bilinguals using func...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390902766879
更新日期:2009-11-01 00:00:00
abstract::In spite of demonstrated validity, Halstead's Category Test has been criticized as overly time consuming. In order to evaluate this assumption, groups of severely head-injured and general neurological cases were administered the Category Test as part of routine evaluation, and the time to completion of the test was re...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638608405190
更新日期:1986-12-01 00:00:00
abstract::West Nile virus infection can result in prolonged subjective complaints of cognitive and functional decline even in the absence of a neuroinvasive form of infection. Persistent cognitive and functional complaints could be a result of general somatic symptoms, emotional distress, or residual central nervous system dama...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390902881918
更新日期:2010-01-01 00:00:00
abstract::The Tower of London (ToL) test is widely used for measuring planning and aspects of problem solving. The primary focus of this study was to asses the relationship among different measures on the ToL. A secondary purpose was to examine the putative relationship between intelligence and working memory with that of ToL p...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390490509574
更新日期:2004-09-01 00:00:00
abstract::Working memory capacity can be conceptualized as the ability to use controlled attention in short term memory (Engle, Tuholski, Laughlin, & Conway, 1999). We tested this idea in young and older adults by combining the task demands of two neuropsychological tests, word span, and Stroop color-naming. Young and older adu...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390490919218
更新日期:2005-07-01 00:00:00
abstract::The study aimed to provide independent data on the specificity of the Nonverbal Medical Symptom Validity Test (NV-MSVT; Green, 2008 ), a new test that combines conventional decision making based on cutoffs with profile analyses in order to identify invalid test performance and to reduce false positive classifications....
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390902791653
更新日期:2010-01-01 00:00:00
abstract::This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular func...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.630653
更新日期:2012-01-01 00:00:00
abstract::While most would agree that mild traumatic brain injury (TBI) is associated with early neuropsychological problems, disagreement exists regarding their persistence and whether they are the cause of the disabilities experienced by some people. The aim of this study was to examine how the criteria used to define mild TB...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.23.6.729.1019
更新日期:2001-12-01 00:00:00