Novel chitosan/collagen scaffold containing transforming growth factor-beta1 DNA for periodontal tissue engineering.

abstract：:The effect of opioids on NO production by LPS-stimulated murine macrophages J774 has been investigated. Morphine (mu and k opioid receptor agonist), DAGO (selective mu receptor agonist) and U50-488H (selective k receptor agonist), added (10(-10)-10(-6) M) to the cells 0.5 h before activation with LPS, significantly in...

journal_title：Biochemical and biophysical research communications

authors： Iuvone T,Capasso A,D'Acquisto F,Carnuccio R

更新日期：1995-07-26 00:00:00

abstract：:Hydrogen sulfide (H(2)S) is recognized as a physiologic mediator produced in a variety of tissues. It is produced by three enzymes, cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST). However, the regulation of H(2)S production by CSE has not well been understoo...

journal_title：Biochemical and biophysical research communications

authors： Mikami Y,Shibuya N,Ogasawara Y,Kimura H

更新日期：2013-02-08 00:00:00

abstract：:Several lines of evidence suggest that TNT detoxification by Phanerochaete chrysosporium is through reduction. Rates of TNT reduction were directly correlated with mycelial mass and TNT concentration. Toxicity was inversely related to the amount of fungus. TNT toxicity was identical in both ligninolytic and nonlignino...

journal_title：Biochemical and biophysical research communications

authors： Stahl JD,Aust SD

更新日期：1993-04-30 00:00:00

abstract：:We report the results of a pilot study to determine the feasibility of using PCR random mutagenesis and in vitro transcription/translation to produce protease resistant full-length or truncated ovine prion proteins (PrP). Using this approach, we show the novel production of protease resistant recombinant ovine prion p...

journal_title：Biochemical and biophysical research communications

authors： Dear DV,Fitzmaurice TJ,Garton S,Richards SJ

更新日期：2001-03-09 00:00:00

abstract：:Britannin (Bri), isolated from Inula aucheriana, is a sesquiterpene lactone (SL), a class of secondary metabolites. Previous studies have suggested the anti-cancer potential of Bri; however, the molecular mechanism remains elusive. The present study investigated the effects of Bri on liver cancer progression. Our find...

journal_title：Biochemical and biophysical research communications

authors： Cui YQ,Liu YJ,Zhang F

更新日期：2018-03-11 00:00:00

abstract：:The collagenase from the larvae Hypoderma lineatum is a serine proteinase sequentially related to the trypsin family. The tryptic peptide containing the serine residue of the active site, labelled with [3H] diisopropylfluorophosphate was isolated and determined to be Ser-Pro-Cys-Phe-Gly-Asp-Ser-Gly-Gly-Pro-(Phe-Ser)-L...

journal_title：Biochemical and biophysical research communications

authors： Lecroisey A,Keil B

更新日期：1983-05-16 00:00:00

abstract：:Heme oxygenase-1, an essential enzyme in heme catabolism, and metallothionein IIA, a small metal-binding protein with clusters of cysteins, are remarkably induced in HeLa cells following the treatment with cadmium or zinc. Both proteins are considered to be involved in the defense system against metal toxicity. Here w...

journal_title：Biochemical and biophysical research communications

authors： Takeda K,Fujita H,Shibahara S

更新日期：1995-02-06 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have emerged as critical regulators of the progression of human cancers, including colorectal cancer (CRC). The study of genome-wide lncRNA expression patterns in metastatic CRC could provide novel mechanism underlying CRC carcinogenesis. In here, we determined the lncRNA expression prof...

journal_title：Biochemical and biophysical research communications

authors： Shen B,Yuan Y,Zhang Y,Yu S,Peng W,Huang X,Feng J

更新日期：2017-06-17 00:00:00

abstract：:Human lymphocyte growth response to mitogen was examined in vitro under different conditions to monitor aspects of carbohydrate utilization in three groups: obese nondiabetic, obese/NIDDM, and normal-weight individuals. Although lymphocyte growth capacity in minimal medium for these three groups was found to be simila...

journal_title：Biochemical and biophysical research communications

authors： Tu KY,Matthews R,Topek NH,Matthews KS

更新日期：1994-07-29 00:00:00

abstract：:One of the mechanisms underlying the induction of human inducible nitric oxide synthase (hiNOS) by cytokines is transcriptional regulation. However, previous reports suggest that in human cells, the cytokine activation of the hiNOS expression is accompanied by a drastic increase in cellular mRNA and protein content, b...

journal_title：Biochemical and biophysical research communications

authors： Nunokawa Y,Oikawa S,Tanaka S

更新日期：1997-04-17 00:00:00

abstract：:The sequence of a novel cGMP-regulated, tetrameric, K(+) selective channel (Sp-tetraKCNG) was discovered in the sea urchin Strongylocentrotus purpuratus. The Sp-tetraKCNG is a single polypeptide made of four KCNG domains similar to voltage-dependent Na(+) and Ca(2+) channels. Each KCNG domain has six transmembrane seg...

journal_title：Biochemical and biophysical research communications

authors： Galindo BE,de la Vega-Beltrán JL,Labarca P,Vacquier VD,Darszon A

更新日期：2007-03-16 00:00:00

abstract：:Although the neuron-restrictive silencer element (NRSE/Regard) has been shown to function as a negative-acting DNA regulatory element to prevent the expression of neuron-specific genes in non-neuronal cells, little is known about its silencing effect on transcription in primary glial cells nor its effect on transcript...

journal_title：Biochemical and biophysical research communications

authors： Tabuchi A,Nakatani C,Nakaoka R,Naruse Y,Kojima T,Mori N,Tsuda M

更新日期：1999-08-02 00:00:00

abstract：:A method for investigating the cellular response of polymorphonuclear leukocytes to various stimuli was introduced using simultaneously native (luminol-independent) and luminol dependent luminescence as an indicator for myeloperoxidase (MPO)-H2O2-halide and O2- mediated reactions. In experimental systems containing lo...

journal_title：Biochemical and biophysical research communications

authors： Roschger P,Graninger W,Klima H

更新日期：1984-09-28 00:00:00

abstract：:In this study, we describe the identification and cloning of a novel member of the nuclear receptor superfamily. This orphan receptor, referred to as ROR gamma, belongs to the ROR/RZR subfamily. The open reading frame of ROR gamma encodes a protein of 560 amino acid residues with a predicted molecular mass of 63 kD. T...

journal_title：Biochemical and biophysical research communications

authors： Hirose T,Smith RJ,Jetten AM

更新日期：1994-12-30 00:00:00

abstract：:There is a close linear correlation between the log partition coefficient (Pa) of a series of 2'-deoxyriboside (dR), 2',3'-didehydro-3'-dideoxyriboside (ddeR), 2',3'-dideoxyriboside (ddR), 3'-fluoro-2',3'-dideoxyriboside (FddR) and 3'-azido-2',3'-dideoxyriboside (AzddR) derivatives of uracil, cytosine, thymine, guanin...

journal_title：Biochemical and biophysical research communications

authors： Balzarini J,Cools M,De Clercq E

更新日期：1989-01-31 00:00:00

abstract：:The Ca(2+)-binding S100A1 protein displays a specific and high expression level in the human myocardium and is considered to be an important regulator of heart contractility. Diminished protein levels detected in dilated cardiomyopathy possibly contribute to impaired Ca(2+) handling and contractility in heart failure....

journal_title：Biochemical and biophysical research communications

authors： Kiewitz R,Acklin C,Schäfer BW,Maco B,Uhrík B,Wuytack F,Erne P,Heizmann CW

更新日期：2003-06-27 00:00:00

abstract：:Recently, T cell cytokines such as IL-17 and IFN-γ have been shown to play important roles in the progression of brain injury induced by ischemia. We have shown that IL-23 from infiltrated macrophages activates γδT cells, thereby inducing IL-17 from these cells. However, deletion of the IL-23 gene in mice showed a mor...

journal_title：Biochemical and biophysical research communications

authors： Konoeda F,Shichita T,Yoshida H,Sugiyama Y,Muto G,Hasegawa E,Morita R,Suzuki N,Yoshimura A

更新日期：2010-11-19 00:00:00

abstract：:The effect of nicotinamide and flavin coenzymes on the 5-lipoxygenase activity has been determined in cell-free extracts from rat polymorphonuclear leukocytes. 5-lipoxygenase was assayed in the presence of 5-hydroperoxyeicosatetraenoic acid (5-HPETE), which caused a 3 to 4-fold stimulation in the maximal conversion of...

journal_title：Biochemical and biophysical research communications

authors： Riendeau D,Leblanc Y

更新日期：1986-12-15 00:00:00

abstract：:Recent studies provide evidence that Sox4 is involved in regulating apoptosis as well as tumorigenesis of various human cancers; however, its role in the apoptotic machinery is not fully understood. Here we describe that the central domain containing glycine-rich region in Sox4, named CD, is a pivotal pro-apoptotic do...

journal_title：Biochemical and biophysical research communications

authors： Hur EH,Hur W,Choi JY,Kim IK,Kim HY,Yoon SK,Rhim H

更新日期：2004-12-03 00:00:00

abstract：:Gliomas are the leading cause of death among adults with primary brain malignancies. Treatment for malignant gliomas remains limited, and targeted therapies have been incompletely explored. Nuclear factor erythroid 2-related factor 2 (Nrf2), a key transcription regulator for antioxidant and detoxification enzymes, is ...

journal_title：Biochemical and biophysical research communications

authors： Jia Y,Wang H,Wang Q,Ding H,Wu H,Pan H

更新日期：2016-01-15 00:00:00

abstract：:Major histocompatibility complex (MHC)-loading enhancers (MLE) have recently attracted attention because of their ability to enhance the efficacy of peptide immunotherapeutics. As small molecular weight compounds, they influence the loading of peptides in MHC molecules by converting them from a non-receptive to a rece...

journal_title：Biochemical and biophysical research communications

authors： Afridi S,Shaheen F,Roetzschke O,Shah ZA,Abbas SC,Siraj R,Makhmoor T

更新日期：2015-01-16 00:00:00

abstract：:Interleukin-4 (IL-4) is a pleiotropic immunomodulatory cytokine produced mainly by T lymphocyte. It is known that many kinds of non-haematopoietic cells, as well as immune cells and haematopoietic cells, express IL-4 receptors. Recently, we found that IL-4 increased hydroxyproline and osteocalcin accumulation and caus...

journal_title：Biochemical and biophysical research communications

authors： Ishibashi H,Karube S,Yamakawa A,Koshihara Y

更新日期：1995-06-26 00:00:00

abstract：:The developing and the adult brain respond in similar ways to ischemia, but also display clear differences. For example, the relative contributions of necrosis and apoptosis to neuronal death may be different, such that apoptotic mechanisms would be more prevalent in the developing brain. During normal development, mo...

journal_title：Biochemical and biophysical research communications

authors： Blomgren K,Zhu C,Hallin U,Hagberg H

更新日期：2003-05-09 00:00:00

abstract：:The quiescent and proliferating status of the cell appears characterized by two different tRNA populations. The tRNA species changed both as relative percentage of total tRNA and in absolute concentration. The changes seem causally related to the proliferation status of the cell as tRNAs from proliferating hepatocytes...

journal_title：Biochemical and biophysical research communications

authors： Kanduc D

更新日期：1996-04-25 00:00:00

abstract：:The Mrr protein of Escherichia coli K12 is a cryptic Type IV restriction endonuclease whose activity appears to be triggered by high pressure stress. In this report we used high pressure to isolate and analyze several Mrr mutants, and generated a new structural model of the Mrr protein. The activity of a number of spo...

journal_title：Biochemical and biophysical research communications

authors： Orlowski J,Mebrhatu MT,Michiels CW,Bujnicki JM,Aertsen A

更新日期：2008-12-19 00:00:00

abstract：:Retinyl ester concentration is regulated by retinoic acid (RA) through an autoregulatory loop, which acts on lecithin:retinol acyltransferase (LRAT). We tested whether retinol esterification activity is downregulated in human mammary carcinoma cells and whether LRAT expression is RAR-regulated. Normal human mammary ep...

journal_title：Biochemical and biophysical research communications

authors： Andreola F,Giandomenico V,Spero R,De Luca LM

更新日期：2000-12-29 00:00:00

abstract：:The aim of this study was to explore the effect of the acetylcholinesterase inhibiting mixture of extracts of Angelica archangelica fruit and Geranium sylvaticum on memory. Furthermore the effect of the main compound, the furanocoumarin imperatorin, which has been shown to affect several neurotransmitters, was studied...

journal_title：Biochemical and biophysical research communications

authors： Sigurdsson S,Gudbjarnason S

更新日期：2013-11-15 00:00:00

abstract：BACKGROUND:Cell fusion is a phenomenon that is observed in various tissues in vivo, resulting in acquisition of physiological functions such as liver regeneration. Fused cells such as hybridomas have also been produced artificially in vitro. Furthermore, it has been reported that cellular reprogramming can be induced b...

journal_title：Biochemical and biophysical research communications

authors： Imai H,Kusakabe KT,Kiso Y,Hattori S,Kai C,Ono E,Kano K

更新日期：2020-01-01 00:00:00

abstract：:Two adenylate cyclase inhibitors: 9-(tetrahydro-2-furyl)adenine and 2'5'-dideoxyadenosine decreased cAMP levels in LH-stimulated immature rat Leydig cells by 20-40%, independent of the concentration of LH. Steroid production was not correlated with this decrease in cAMP, but was increased (146%). The phorbol ester 4 b...

journal_title：Biochemical and biophysical research communications

authors： Themmen AP,Hoogerbrugge JW,Rommerts FF,van der Molen HJ

更新日期：1985-05-16 00:00:00

abstract：:Human prostasin was recently identified as a potential regulator of epithelial sodium channel (ENaC) function. Through the use of positional scanning combinatorial substrate libraries, prostasin was shown to have a preference for poly-basic substrates: in position P4 preference was for arginine or lysine; in P3 prefer...

journal_title：Biochemical and biophysical research communications

authors： Shipway A,Danahay H,Williams JA,Tully DC,Backes BJ,Harris JL

更新日期：2004-11-12 00:00:00