The Schizotypic Syndrome Questionnaire (SSQ): Psychometrics, validation and norms.

abstract：OBJECTIVE:While "dual diagnosis" involving both psychiatric and substance use disorders has long been a focus of schizophrenia research, recent studies have advocated for a shift of focus to multimorbidity, addressing comorbidity from both additional psychiatric disorders and substance use disorders. We hypothesized th...

journal_title：Schizophrenia research

authors： Bhalla IP,Stefanovics EA,Rosenheck RA

更新日期：2018-11-01 00:00:00

abstract：:The purpose of this study was to examine the concurrent validity of a Wechsler Adult Intelligence Scale-Revised (WAIS-R) seven subtest short form. Researchers have shown that the IQ scores estimated by this short form correlate highly with full-form IQ scores in several patient populations. We compared the full WAIS-R...

journal_title：Schizophrenia research

authors： Iverson GL,Guirguis M,Green P

更新日期：1998-03-10 00:00:00

abstract：:Disrupted-in-Schizophrenia 1 (DISC1), a strong candidate gene for schizophrenia and other mental disorders, regulates neurodevelopmental processes including neurogenesis, neuronal migration, neurite outgrowth and spine development. Glycogen synthase kinase-3 (GSK3) directly interacts with DISC1 and also plays a role i...

journal_title：Schizophrenia research

authors： Lee FH,Kaidanovich-Beilin O,Roder JC,Woodgett JR,Wong AH

更新日期：2011-06-01 00:00:00

abstract：:This study determines that visuospatial working memory (VSWM) deficits are evident in adolescent-onset schizophrenia, while the spatial strategy and spatial span components of VSWM are spared. These findings imply that frontal-striatal-parietal neural networks are dysfunctional in adolescent-onset schizophrenia, while...

journal_title：Schizophrenia research

authors： Vance A,Hall N,Bellgrove MA,Casey M,Karsz F,Maruff P

更新日期：2006-10-01 00:00:00

abstract：:Previous studies suggested that African American patients with psychotic disorders receive higher doses of antipsychotic medication than white patients, are more likely to receive depot antipsychotics, and are less likely to be prescribed second-generation antipsychotics. African-American men in particular may be most...

journal_title：Schizophrenia research

authors： Arnold LM,Strakowski SM,Schwiers ML,Amicone J,Fleck DE,Corey KB,Farrow JE

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Recent empirical evidence [Maher, B.A., Manschreck, T.C., Linnert, J., Candela, S., 2005. Quantitative assessment of the frequency of normal associations in the utterances of schizophrenia patients and healthy controls. Schizophrenia Research 78, 219-224] shows that schizophrenia patients produce an elevated...

journal_title：Schizophrenia research

authors： Lenzenweger MF,Miller AB,Maher BA,Manschreck TC

更新日期：2007-09-01 00:00:00

abstract：:The author previously proposed that schizophrenia has similar cytokine expression compared to melanoma, a neural crest cell tumor. One possible tumor model of schizophrenia includes anti-NMDA receptor encephalitis, a paraneoplastic syndrome. While examining the possible relationship of neural crest cell tumors to schi...

journal_title：Schizophrenia research

authors： Brown JS Jr

更新日期：2016-10-01 00:00:00

abstract：:The current study examined the factor structure of the Brief Negative Symptom Scale (BNSS), a next-generation negative symptom rating instrument developed in response to the NIMH-sponsored Consensus Development Conference on Negative Symptoms. Participants included 146 individuals with a DSM-IV diagnosis of schizophre...

journal_title：Schizophrenia research

authors： Strauss GP,Hong LE,Gold JM,Buchanan RW,McMahon RP,Keller WR,Fischer BA,Catalano LT,Culbreth AJ,Carpenter WT,Kirkpatrick B

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Aripiprazole has been associated with a low prevalence of metabolic side effects as compared to other second generation antipsychotic (SGA) medications mostly in patients with long standing illness. The purpose of the present study was to assess specifically the effectiveness and safety of aripiprazole as ...

journal_title：Schizophrenia research

authors： Malla A,Mustafa S,Rho A,Abadi S,Lepage M,Joober R

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Second-generation antipsychotics (SGAs) increase the risk of type 2 diabetes. The mechanism is thought to center on drug-induced weight gain, which starts the dysmetabolic cascade of insulin resistance, increased insulin production and pancreatic beta-cell failure. An independent effect of SGAs on insulin se...

journal_title：Schizophrenia research

authors： Manu P,Correll CU,Wampers M,van Winkel R,Yu W,Shiffeldrim D,Kane JM,De Hert M

更新日期：2013-02-01 00:00:00

abstract：:Meta-analyses of randomized controlled trials support the efficacy of cognitive behavioral therapy (CBT) in the treatment of symptoms of schizophrenia refractory to antipsychotic medication. This article addresses the issue of medium term durability. A five-year follow-up was undertaken of a sample of 90 subjects who ...

journal_title：Schizophrenia research

authors： Turkington D,Sensky T,Scott J,Barnes TR,Nur U,Siddle R,Hammond K,Samarasekara N,Kingdon D

更新日期：2008-01-01 00:00:00

abstract：:Language disturbance is one of the main diagnostic features in schizophrenia and abnormalities of brain language areas have been consistently found in schizophrenic patients. The main aim of this study was to describe the impairment of micro and macrolinguistic abilities in a group of twenty-nine schizophrenic patient...

journal_title：Schizophrenia research

authors： Marini A,Spoletini I,Rubino IA,Ciuffa M,Bria P,Martinotti G,Banfi G,Boccascino R,Strom P,Siracusano A,Caltagirone C,Spalletta G

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Deficits in the mediodorsal and anterior nuclei of the thalamus may contribute to the psychopathological symptoms of schizophrenia. These thalamic nuclei have been found to be abnormal in schizophrenia and have close connections with other brain structures implicated in the disorder. We therefore examined sch...

journal_title：Schizophrenia research

authors： Jakary A,Vinogradov S,Feiwell R,Deicken RF

更新日期：2005-07-15 00:00:00

abstract：BACKGROUND:Clozapine is the drug of choice for patients with unsatisfactory response to routine antipsychotic treatment. Polypharmacy is widely used among patients having clozapine-resistant schizophrenia, although no solid evidence exists for any effective augmentation therapy for this patient population. We aimed to ...

journal_title：Schizophrenia research

authors： Tiihonen J,Wahlbeck K,Kiviniemi V

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:This study sought to evaluate levels of insight and change in insight in subjects with schizophrenia and other major psychiatric disorders. This study also evaluated the relationship of insight to acute psychopathology. METHOD:One-hundred and eighty-seven subjects consecutively admitted to an acute care psyc...

journal_title：Schizophrenia research

authors： Weiler MA,Fleisher MH,McArthur-Campbell D

更新日期：2000-09-29 00:00:00

abstract：:Childhood trauma is a risk factor for the onset of schizophrenic psychosis. Because the psychosis phenotype can be described as a continuum with varying levels of severity and persistence, childhood trauma might likewise increase the risk for psychotic experiences below the diagnostic threshold. But the impact of stre...

journal_title：Schizophrenia research

authors： Rössler W,Ajdacic-Gross V,Rodgers S,Haker H,Müller M

更新日期：2016-04-01 00:00:00

abstract：:Grey matter brain networks are disrupted in schizophrenia, but it is still unclear at which point during the development of the illness these disruptions arise and whether these can be associated with behavioural predictors of schizophrenia. We investigated if single-subject grey matter networks were disrupted in a sa...

journal_title：Schizophrenia research

authors： Tijms BM,Sprooten E,Job D,Johnstone EC,Owens DG,Willshaw D,Seriès P,Lawrie SM

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To explore the impact of the introduction of newer antipsychotic long-acting injections (LAIs) on trends in LAI prescribing and characteristics associated with initiation of LAIs in naturalistic conditions. METHODS:The study was performed using reimbursement data from the French Insurance Healthcare system. ...

journal_title：Schizophrenia research

authors： Verdoux H,Pambrun E,Tournier M,Bezin J,Pariente A

更新日期：2016-12-01 00:00:00

abstract：:Sleep disturbances have been reliably reported in patients with schizophrenia, thus suggesting that abnormal sleep may represent a core feature of this disorder. Traditional electroencephalographic studies investigating sleep architecture have found reduced deep non-rapid eye movement (NREM) sleep, or slow wave sleep ...

journal_title：Schizophrenia research

authors： Ferrarelli F,Tononi G

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Eye movement abnormalities have been identified in schizophrenia; however, their relevance to cognition is still unknown. In this study, we explored the general relationship between eye movements and cognitive function. METHODS:The three eye movement measures (scanpath length, horizontal position gain, and ...

journal_title：Schizophrenia research

authors： Morita K,Miura K,Fujimoto M,Yamamori H,Yasuda Y,Kudo N,Azechi H,Okada N,Koshiyama D,Ikeda M,Kasai K,Hashimoto R

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:The main goal of the present study was to analyze levels of cytokines of the interleukin family (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8 and IL-10), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (MCP1), tumor necrosis factor-alpha (TNF-α), and vascular endothelial and endothelial growth factors (V...

journal_title：Schizophrenia research

authors： Haring L,Koido K,Vasar V,Leping V,Zilmer K,Zilmer M,Vasar E

更新日期：2015-12-01 00:00:00

abstract：:Noises elicit startle blinks that are inhibited when immediately (approximately 100 ms) preceded by non-startling prepulses, perhaps reflecting automatic sensory gating. Startle blinks are facilitated when preceded by prepulses at longer lead intervals, perhaps reflecting strategic processes. Event-related brain poten...

journal_title：Schizophrenia research

authors： Ford JM,Roth WT,Menon V,Pfefferbaum A

更新日期：1999-05-25 00:00:00

abstract：:Research suggests that social stress exposure influences illness presentation and course among youth at clinical high-risk (CHR) for psychosis, though less is known about the extent to which self-reported perceptions of social stress relate to the severity of positive symptoms. Importantly, despite the notion that you...

journal_title：Schizophrenia research

authors： Millman ZB,Pitts SC,Thompson E,Kline ER,Demro C,Weintraub MJ,DeVylder JE,Mittal VA,Reeves GM,Schiffman J

更新日期：2018-02-01 00:00:00

abstract：:In 1873 Skeffington Lutwidge, a Lunacy Commission inspector of asylums in England, was killed by an asylum patient. Lutwidge was the uncle and close friend of Charles Lutwidge Dodgson, also known as Lewis Carroll. One year later, Carroll began writing The Hunting of the Snark, a poem whose meaning has mystified Carrol...

journal_title：Schizophrenia research

authors： Torrey EF,Miller J

更新日期：2014-12-01 00:00:00

abstract：:Though negative symptoms in schizophrenia are associated with a host of deleterious outcomes (e.g., White et al., 2009), not all individuals with schizophrenia suffer from negative symptoms (e.g., Blanchard et al., 2005). Thus, methods to quickly screen and identify patients for more intensive clinical interview asses...

journal_title：Schizophrenia research

authors： Park SG,Llerena K,McCarthy JM,Couture SM,Bennett ME,Blanchard JJ

更新日期：2012-03-01 00:00:00

abstract：:Studying Klinefelter syndrome (47,XXY), a genetically defined disorder characterized by the presence of an additional X chromosome, can reveal insights into genotype-phenotype associations. Increased vulnerability to psychiatric disorders characterized by difficulties in social interactions, such as schizophrenia and ...

journal_title：Schizophrenia research

authors： van Rijn S,Swaab H,Aleman A,Kahn RS

更新日期：2006-06-01 00:00:00

abstract：:Stigma may undermine the well-being of young people at risk of psychosis. We therefore measured self-labeling, stigma variables and well-being at baseline and again one year later among 77 at-risk participants. An increase in self-labeling during this period predicted heightened stigma stress after one year and a decr...

journal_title：Schizophrenia research

authors： Rüsch N,Müller M,Heekeren K,Theodoridou A,Metzler S,Dvorsky D,Corrigan PW,Walitza S,Rössler W

更新日期：2014-09-01 00:00:00

abstract：:Schizophrenic delusions are important target symptoms for treatment. This study aims to identify predictors of delusion formation. Two samples of schizophrenic patients (total n = 131) are examined prospectively every second week during a period of 6 months. In one sample (n = 60) delusion formation (n = 27; 45%) is c...

journal_title：Schizophrenia research

authors： Jørgensen P

更新日期：1998-06-22 00:00:00

abstract：BACKGROUND:Psychotic-like experiences (PLEs) during adolescence are not uncommon and potentially represent a clinical and public health concern. A greater understanding of their aetiology and patterns of change over time is needed. We aimed to describe trajectories of PLEs during adolescence, and examine their associat...

journal_title：Schizophrenia research

authors： Thapar A,Heron J,Jones RB,Owen MJ,Lewis G,Zammit S

更新日期：2012-09-01 00:00:00

abstract：:In previous studies of self-monitoring in schizophrenia, patients have exhibited reductions in the amplitude of the error-related negativity (ERN), a component of the event-related brain potential (ERP) elicited most prominently immediately following the execution of incorrect responses. In the current study, we exami...

journal_title：Schizophrenia research

authors： Morris SE,Heerey EA,Gold JM,Holroyd CB

更新日期：2008-02-01 00:00:00