Topographic screening of donor eyes for previous refractive surgery.

Abstract:

PURPOSE:To determine whether donor eyes had previous refractive surgery using Orbscan (Bausch & Lomb Surgical) corneal topography. SETTING:Lions Eye Bank of Oregon, Portland, Oregon, USA, and Maisonneuve-Rosemont, Hospital, Montreal, Quebec, Canada. METHODS:Orbscan corneal topographies of 50 donor eyes from the Lions Eye Bank of Oregon were obtained; 10 eyes had previous refractive surgery (6 laser in situ keratomileusis, 2 photorefractive keratectomy, 2 radial keratotomy) to correct myopia, and 40 had not had surgery. Algorithms based on corneal anterior and posterior elevations and anterior tangential curvature were developed: The difference in curvature (DC) was based on the difference in the mean anterior tangential curvature between central and midperipheral areas; difference in elevation (DE) represented the difference between the anterior and posterior central elevations. Receiver-operating characteristic (ROC) curves for each algorithm were obtained, and sensitivity values at fixed specificities were calculated. RESULTS:The mean area under the ROC curve, which corresponds to the probability of correctly identifying the presence of a previous refractive surgery, was 0.853 +/- 0.079 (SE) for DC and 0.933 +/- 0.057 for DE. The DC algorithm resulted in a sensitivity of 80% for a specificity of 87.5%, and DE yielded a sensitivity of 90% for a specificity of 92.5%. There was a strong correlation between the value of the DE and DC algorithms and the amount of previous refractive surgery (DC: r = 0.84, P = .008; DE: r = 0.76, P = .028). CONCLUSION:The results led to a proposed criteria-based system using Orbscan corneal topography to screen eye-bank eyes for previous refractive surgery.

authors

Hick S,Laliberté JF,Meunier J,Ousley PJ,Terry MA,Brunette I

doi

10.1016/j.jcrs.2005.12.035

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

309-17

issue

2

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(05)01033-3

journal_volume

32

pub_type

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