Abstract:
:In 1998, two distinct and exciting scientific fields emerged which have profoundly shaped the current direction of biomedical research. The discovery of RNA interference (RNAi) and the derivation of human embryonic stem (ES) cells have yielded exciting new possibilities for researchers and clinicians alike. While fundamentally different, aspects from these two fields may be combined to yield extraordinary scientific and medical benefits. Here, we review the prospects of combining RNAi and ES cell manipulation for both basic research and future therapies, as well as current limitations and obstacles that need to be overcome.
journal_name
Gene Therjournal_title
Gene therapyauthors
Heidersbach A,Gaspar-Maia A,McManus MT,Ramalho-Santos Mdoi
10.1038/sj.gt.3302723subject
Has Abstractpub_date
2006-03-01 00:00:00pages
478-86issue
6eissn
0969-7128issn
1476-5462pii
3302723journal_volume
13pub_type
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