Caught in the act: in vivo molecular imaging of the transcription factor NF-kappaB after myocardial infarction.

abstract：:In order to understand gene regulation during wood formation, we cloned a MYB46-like gene in hybrid aspen, Populus tremula x tremuloides, called Pt x tMYB021. Phylogenetic and paired identity analysis of MYB46-like genes in Populus and Arabidopsis reveals relationships between paralogous pairs of Populus MYB46-like pr...

journal_title：Biochemical and biophysical research communications

authors： Winzell A,Aspeborg H,Wang Y,Ezcurra I

更新日期：2010-04-09 00:00:00

abstract：:Fragments of the human glutathione S-transferase pi gene and 15 kb of its 5' flanking region have been fused to the chloramphenicol acetyl transferase (CAT) reporter gene. Transfection into a number of human cell lines (Hela, HepG2, MCF7 and EJ) has demonstrated that the AP1 binding site, located between nucleotides -...

journal_title：Biochemical and biophysical research communications

authors： Xia CL,Cowell IG,Dixon KH,Pemble SE,Ketterer B,Taylor JB

更新日期：1991-04-15 00:00:00

abstract：:The efp, a member of the RING finger family, was previously identified as an estrogen responsive gene. Here, we characterized basal promoter of the human efp gene. Transcription initiation site was found at position -60 G relative to the site for translation initiation, and TATA motif was absent. Deletion and mutation...

journal_title：Biochemical and biophysical research communications

authors： Ikeda K,Inoue S,Orimo A,Sano M,Watanabe T,Tsutsumi K,Muramatsu M

更新日期：1997-07-30 00:00:00

abstract：:Acute promyelocytic leukemia (APL) is characterized by a specific chromosome translocation t(15;17), which results in the fusion of the promyelocytic leukemia gene (PML) and retinoic acid receptor alpha gene (RARalpha). APL can be effectively treated with the cell differentiation inducer all-trans retinoic acid (ATRA)...

journal_title：Biochemical and biophysical research communications

authors： Lee KH,Chang MY,Ahn JI,Yu DH,Jung SS,Choi JH,Noh YH,Lee YS,Ahn MJ

更新日期：2002-09-06 00:00:00

abstract：:The aims of this study are to identify the sex steroid-metabolizing cytochrome P450 enzymes of the vomeronasal organ (VNO) and to determine the activities of VNO microsomes to metabolize estradiol, progesterone, and testosterone. Several P450 isoforms, including CYP1A2, CYP2A, CYP2B, CYP2C, CYP2G1, and CYP3A, NADPH P4...

journal_title：Biochemical and biophysical research communications

authors： Gu J,Dudley C,Su T,Spink DC,Zhang QY,Moss RL,Ding X

更新日期：1999-12-09 00:00:00

abstract：:The DNA-binding activity of a 42-kDa phosphoprotein from salivary gland cells and cultured epithelial cells of Chironomus tentans have been analyzed by the Southwestern technique. Both the salivary gland and the epithelial cell 42-kDa polypeptides were found to be single-stranded DNA-binding proteins. They bind to sin...

journal_title：Biochemical and biophysical research communications

authors： Stigare J,Egyhazi E

更新日期：1991-05-15 00:00:00

abstract：:Eleven genes, including pax2a, were selected as candidate ovulation-inducing genes on the basis of microarray analysis and RNA sequencing in our previous study. The purpose of this study was to investigate the role of the pax2a gene in the ovulation-inducing process. F2 pax2a homozygous mutant zebrafish possessing a d...

journal_title：Biochemical and biophysical research communications

authors： Pachoensuk T,Fukuyo T,Wanlada K,Rezanujjaman M,Rahaman MM,Sasaoka K,Sarwar Jyoti MM,Rana MR,Ali MH,Tokumoto T

更新日期：2020-12-10 00:00:00

abstract：:Recent studies revealed dramatic changes in circadian clock genes' expression during the perinatal period. In this study, we characterized DNA methylation for three clock genes mPer1, mPer2, and mCry1 at their selected promoter regions during development. Results for the suprachiasmatic nucleus (SCN) and liver (at emb...

journal_title：Biochemical and biophysical research communications

authors： Ji Y,Qin Y,Shu H,Li X

更新日期：2010-01-22 00:00:00

abstract：:Transforming growth factor alpha (TGF alpha) induces dose- and time-dependent stimulation of prostacyclin (PGI2) production by cultured human umbilical vein endothelial cells. The lowest stimulatory concentration of TGF alpha was 0.1 ng/ml and the maximal response, a 2.7-fold rise, was obtained with 10 ng/ml. The stim...

journal_title：Biochemical and biophysical research communications

authors： Ristimäki A

更新日期：1989-05-15 00:00:00

abstract：:Liraglutide, a glucagon-like peptide 1 (GLP-1) analogue, could reverse NAFLD-induced liver damage by improving metabolic profiles, but the exact molecular mechanism has not been elucidated. Sestrin2 is a novel antioxidant protein, essential for regulating metabolic homeostasis. However, whether sestrin2-mediated redox...

journal_title：Biochemical and biophysical research communications

authors： Han X,Ding C,Zhang G,Pan R,Liu Y,Huang N,Hou N,Han F,Xu W,Sun X

更新日期：2020-05-14 00:00:00

abstract：:Spectroscopic analysis of the interaction of the epimeric 20-hydroperoxy derivatives of cholesterol with bovine adrenocortical cytochrome P-450scc preparations suggested the formation of a transient species. The intermediate was detected at 4 degrees C and characterized by a minimum at 412 nm in the difference spectru...

journal_title：Biochemical and biophysical research communications

authors： Larroque C,van Lier JE

更新日期：1983-04-29 00:00:00

abstract：:Glial glutamate transporter GLT-1 mRNA was selectively induced in C6 glioma cells exposed to hypertonic stress (HS), while the expression of two other subtypes, GLAST and EAAC1, was suppressed. HS increased phosphorylation of the MAPK family, ERK, p38 MAPK, and JNK. Treatment with a PKC inhibitor showed that phosphory...

journal_title：Biochemical and biophysical research communications

authors： Imura T,Shimohama S,Kageyama T,Kimura J

更新日期：1999-11-01 00:00:00

abstract：:Dysregulation of autophagy has been observed in obesity and type 2 diabetes. Salt-inducible kinase 2 (SIK2), a member of the AMPK-related kinase family, is downregulated in adipocytes from obese or insulin resistant individuals and was previously demonstrated to regulate autophagy in cancer and normal cell lines. The ...

journal_title：Biochemical and biophysical research communications

authors： Negoita F,Säll J,Morén B,Stenkula K,Göransson O

更新日期：2019-01-15 00:00:00

abstract：:Ubiquitin C-terminal hydrolase-L3 (UCH-L3) is among the deubiquitinating enzymes (DUBs) that cleave ubiquitin (Ub) from Ub precursors or protein substrates. Many DUBs have been shown to participate in cancer progression in various tissues. However, the mechanism and role of UCH-L3 in carcinogenesis has largely been un...

journal_title：Biochemical and biophysical research communications

authors： Song HM,Lee JE,Kim JH

更新日期：2014-09-26 00:00:00

abstract：:This study presents a kinetic analysis of the response to wounding in rice plants. In particular, jasmonic acid, salicylic acid, and lipoxygenase activity were measured in leaves of wounded rice plants during the early tillering phase. The results show that endogenous jasmonic acid transiently increases to a maximum 3...

journal_title：Biochemical and biophysical research communications

authors： Lee A,Cho K,Jang S,Rakwal R,Iwahashi H,Agrawal GK,Shim J,Han O

更新日期：2004-06-04 00:00:00

abstract：:Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that ...

journal_title：Biochemical and biophysical research communications

authors： Fu J,Xu X,Kang L,Zhou L,Wang S,Lu J,Cheng L,Fan Z,Yuan B,Tian P,Zheng X,Yu C,Ye Q,Lv Z

更新日期：2014-03-07 00:00:00

abstract：:To elucidate whether p21waf-1/cip-1/sdi-1 expression is associated with loss of growth potential of hepatocytes of old rats, we determined p21waf-1/cip-1/sdi-1 expression of hepatocytes from old (30 months) rats during the cell cycle in primary culture. A high level of expression of p21waf-1/cip-1/sdi-1 was detected a...

journal_title：Biochemical and biophysical research communications

authors： Sawada N,Kojima T,Obata H,Saitoh M,Isomura H,Kokai Y,Satoh M,Mori M

更新日期：1996-11-21 00:00:00

abstract：:Microbial redox reactions of inorganic sulfur compounds play a vital role in balancing the turnover of this element in the environment. These vital reactions are carried out by the enzyme system encoded by the sox operon. The central player of the sulfur oxidation biochemistry is the SoxY-Z protein complex. Another pr...

journal_title：Biochemical and biophysical research communications

authors： Bagchi A

更新日期：2011-10-22 00:00:00

abstract：:gamma-glutamyltranspeptidase (GGT) is a key enzyme implicated in the homeostasis of intracellular reduced glutathione (GSH) and hence in the regulation of the cellular redox state. Besides, the extracellular cleavage of GSH by GGT leads to reactive oxygen species (ROS) production, depending on the generation and enhan...

journal_title：Biochemical and biophysical research communications

authors： Accaoui MJ,Enoiu M,Mergny M,Masson C,Dominici S,Wellman M,Visvikis A

更新日期：2000-10-05 00:00:00

abstract：:Arctigenin is a bioactive constituent from dried seeds of Arctium lappa L., which was traditionally used as medicine. Arctigenin exhibits various bioactivities, but its effects on blood pressure regulation are still not widely studied. In this study, we investigated antihypertensive effects of arctigenin by long-term ...

journal_title：Biochemical and biophysical research communications

authors： Liu Y,Wang G,Yang M,Chen H,zhao Y,Yang S,Sun C

更新日期：2015-12-25 00:00:00

abstract：:Intestinal challenge with cholera toxin induces the synthesis of a hormone-like protein which counteracts intestinal hypersecretion. This study shows that the protein also inhibits GABA transport across the plasma membrane of Deiters' cells in rabbits. The inhibitory action of the protein was dose dependent, and 10(3)...

journal_title：Biochemical and biophysical research communications

authors： Lange S,Lönnroth I,Palm A,Hydén H

更新日期：1985-08-15 00:00:00

abstract：:This study was designed to compare the temporal changes of gene expression profile in osteoblastic cell lines (SaOS-2) treated with low-intensity pulsed ultrasound stimulation (LIPUS) using complementary DNA (cDNA) microarrays. SaOS-2 cells were treated with LIPUS for 20min. Thereafter, cells were harvested and RNA wa...

journal_title：Biochemical and biophysical research communications

authors： Lu H,Qin L,Lee K,Cheung W,Chan K,Leung K

更新日期：2009-01-16 00:00:00

abstract：:The p21(WAF-1) promoter contains binding sites for a number of transcription factors which mediate its activation by a variety of external signals. Moreover, it has been reported that the transcription factors involved in p21(WAF-1) activation by certain signaling factors, like the phorbol ester TPA, may vary in diffe...

journal_title：Biochemical and biophysical research communications

authors： Schavinsky-Khrapunsky Y,Huleihel M,Aboud M,Torgeman A

更新日期：2003-05-16 00:00:00

abstract：:Opening of high conductance permeability transition pores in mitochondria initiates onset of the mitochondrial permeability transition (MPT). The MPT is a causative event, leading to necrosis and apoptosis in hepatocytes after oxidative stress, Ca(2+) toxicity, and ischemia/reperfusion. CsA blocks opening of permeabil...

journal_title：Biochemical and biophysical research communications

authors： Kim JS,He L,Lemasters JJ

更新日期：2003-05-09 00:00:00

abstract：:Inflammatory processes within the cornea are known to be associated with corneal neovascularization (CN). We examined the effects of inflammatory mediators on the expression of angiogenic factors by corneal cells. TNF-alpha and IL-1 induced VEGF-A secretion by corneal fibroblasts (HCRF) and this was inhibited signific...

journal_title：Biochemical and biophysical research communications

authors： Kommineni VK,Nagineni CN,William A,Detrick B,Hooks JJ

更新日期：2008-09-26 00:00:00

abstract：:The ras family of oncogenes, as well as the transplasma membrane electron transport system, have been implicated in cellular growth control. Here we present evidence that the Ha-ras oncoprotein increases the activity of the transplasma membrane electron transport system in the mouse embryonic fibroblast cell line C3H1...

journal_title：Biochemical and biophysical research communications

authors： Crowe RA,Taparowsky EJ,Crane FL

更新日期：1993-10-29 00:00:00

abstract：:(1S,5S,6R,7R)-7-Chloro-3-imino-5-methyl-2-azabicyclo[4.1.0]heptane hydrochloride (ONO-1714), a novel cyclic amidine analogue, inhibits human inducible nitric oxide (iNOS) with a K(i) of 1.88 nM and rodent iNOS with similar potency in vitro. ONO-1714 was found to be 10-fold selective for human iNOS over human endotheli...

journal_title：Biochemical and biophysical research communications

authors： Naka M,Nanbu T,Kobayashi K,Kamanaka Y,Komeno M,Yanase R,Fukutomi T,Fujimura S,Seo HG,Fujiwara N,Ohuchida S,Suzuki K,Kondo K,Taniguchi N

更新日期：2000-04-13 00:00:00

abstract：:Labial grooves in maxillary incisors have been reported in several wild-type rodent species. Previous studies have reported age-dependent labial grooves occur in moderate prevalence in C57BL/6 mice; however, very little is known about the occurrence of such grooves. In the present study, we observed age-dependent groo...

journal_title：Biochemical and biophysical research communications

authors： Ota MS,Kondo K,Li Y,Iseki S,Yamashita A,Gibson CW,Kondo T

更新日期：2018-02-05 00:00:00

abstract：:Platelets are an important place for the storage of angiogenic factors, such as vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). The present study aims to investigate the interaction between BDNF-TrkB pathway and platelet activation during tumor development. In an orthotopic hepa...

journal_title：Biochemical and biophysical research communications

authors： Yang ZF,Ho DW,Lau CK,Tam KH,Lam CT,Poon RT,Fan ST

更新日期：2006-08-04 00:00:00

abstract：:A monoclonal antibody (MaB) against mouse sarcoma DNA polymerase alpha was isolated from the culture medium of an IgG-secreting hybridoma. The MaB demonstrated reactivity against two murine DNA polymerase alpha preparations and a calf thymus DNA polymerase alpha. Murine sarcoma polymerase was activated in vitro by pho...

journal_title：Biochemical and biophysical research communications

authors： Sylvia VL,Norman JO,Curtin GM,Busbee DL

更新日期：1986-11-26 00:00:00