Cell-wall-bound metal ions are not taken up in Neurospora crassa.

Abstract:

:To establish the relevance of the cell wall in metal ion transport, cobalt uptake was examined in Neurospora crassa. Cobalt taken up was largely surface bound (>90%), resulting in a release of calcium and magnesium. Surface-bound cobalt could not enter intracellular locations upon further incubation of mycelia in a metal-free medium. Saturation of the surface with one metal augured subsequent dose-dependent entry of a different metal into intracellular locations. In comparison with the cobalt-resistant mutant, the cobalt-sensitive strain of N. crassa bound less cobalt on the surface but with significant intracellular accumulation. Our results demonstrate the importance of the cell wall in metal transport, toxicity, and resistance in fungi.

journal_name

Can J Microbiol

authors

Latha JN,Rashmi K,Mohan PM

doi

10.1139/w05-096

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

1021-6

issue

12

eissn

0008-4166

issn

1480-3275

pii

w05-096

journal_volume

51

pub_type

杂志文章
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