No association of complexin1 and complexin2 genes with schizophrenia in a Japanese population.

abstract：:Deficits in emotion perception are common in people with schizophrenia and current research has focused on improving these deficits. In our previous research, we demonstrated that directing attention to salient facial features via attention shaping can improve these deficits among inpatients. In this study, we examine...

journal_title：Schizophrenia research

authors： Combs DR,Chapman D,Waguspack J,Basso MR,Penn DL

更新日期：2011-04-01 00:00:00

abstract：:We previously reported a schizophrenia associated reduction of neuronal and oligodendrocyte number in the anterior principal thalamic nucleus (APN) in a cohort of severely impaired elderly subjects with schizophrenia (SZ) relative to age matched nonpsychiatric controls (NCs). The present study was undertaken to determ...

journal_title：Schizophrenia research

authors： Byne W,Tatusov A,Yiannoulos G,Vong GS,Marcus S

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:EEG power in the delta, theta and beta1 bands has been shown to be positively correlated with negative symptoms in first episode psychotic patients. The present study investigates this correlation in an "at risk mental state for psychosis" (ARMS) with the aim to improve prediction of transition to psychosi...

journal_title：Schizophrenia research

authors： Zimmermann R,Gschwandtner U,Wilhelm FH,Pflueger MO,Riecher-Rössler A,Fuhr P

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:A false sense of reality is a characteristic of schizophrenia spectrum disorders (SSD). Reality confusion may also emanate from posterior orbitofrontal cortex (OFC) lesions, as evident in confabulations that patients act upon and disorientation. This confusion can be measured by repeated runs of a continuous...

journal_title：Schizophrenia research

authors： Thézé R,Manuel AL,Pedrazzini E,Chantraine F,Patru MC,Nahum L,Guggisberg AG,Schnider A

更新日期：2019-02-01 00:00:00

abstract：:Although pharmacologic treatments are available for patients with schizophrenia, little is known about how prescription patterns of atypical antipsychotic agents are related to patient characteristics. In this study, we examined the association between patient characteristics and the likelihood of being initiated on o...

journal_title：Schizophrenia research

authors： Ren XS,Kazis LE,Lee AF,Huang YH,Hamed A,Cunningham F,Herz L,Miller DR

更新日期：2005-09-15 00:00:00

abstract：:A review of 65 studies of individuals with schizophrenia who had never been treated with antipsychotic medications indicates significant abnormalities in brain structure and function. Neurological and neuropsychological measures show the most consistent and largest group differences between those affected and normal c...

journal_title：Schizophrenia research

authors： Torrey EF

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:We examined cognitive deficits before and after onset of schizophrenia in a longitudinal study that: 1) covers a long time interval; 2) minimizes test unreliability by including the identical measure at both childhood and post-onset cognitive assessments; and 3) minimizes bias by utilizing a population-based...

journal_title：Schizophrenia research

authors： Kremen WS,Vinogradov S,Poole JH,Schaefer CA,Deicken RF,Factor-Litvak P,Brown AS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Advanced paternal age (APA) is associated with increased risk for schizophrenia, but its effect on treatment response has not been longitudinally studied. METHODS:Association of parental ages at the time of the child's birth with age of onset, initial symptom severity and treatment response (to placebo and ...

journal_title：Schizophrenia research

authors： Opler M,Malaspina D,Gopal S,Nuamah I,Savitz AJ,Singh J,Hough D

更新日期：2013-12-01 00:00:00

abstract：:A sensitive radioimmunoassay was developed to determine the steady-state, fixed-dose pharmacokinetic profile of fluphenazine decanoate in nine outpatients. To see if neuroleptic blood levels measured by this assay correlated with a clinical event, we performed a cross-sectional study of fluphenazine blood levels in 11...

journal_title：Schizophrenia research

authors： Glazer WM

更新日期：1988-11-01 00:00:00

abstract：INTRODUCTION:This study investigates the effect of exposure to "The Troubles" (the period of civil unrest from 1968 onwards) in Northern Ireland on symptomatology in people with schizophrenia. METHOD:Eighty-two participants were assessed on a number of psychiatric rating scales and on measures of trauma, including an ...

journal_title：Schizophrenia research

authors： Mulholland C,Boyle C,Shannon C,Huda U,Clarke L,Meenagh C,Dempster M

更新日期：2008-07-01 00:00:00

abstract：:Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

journal_title：Schizophrenia research

authors： Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

更新日期：1997-08-29 00:00:00

abstract：:Cannabis use is highly prevalent worldwide and it is associated with psychosis, but its effects on brain structure and cognition are still controversial. The aim of this paper is to investigate cognitive functioning and brain structure in patients with their first episode of psychosis who used Cannabis. We examined gr...

journal_title：Schizophrenia research

authors： Cunha PJ,Rosa PG,Ayres Ade M,Duran FL,Santos LC,Scazufca M,Menezes PR,dos Santos B,Murray RM,Crippa JA,Busatto GF,Schaufelberger MS

更新日期：2013-07-01 00:00:00

abstract：:[(3)H]ketanserin binding to 5HT(2A) receptors was measured in the left planum temporale (sensory speech cortex) from schizophrenic and non-schizophrenic (control) subjects using both particulate membranes and tissue sections. There was a significant decrease in the affinity of [(3)H]ketanserin binding to particulate m...

journal_title：Schizophrenia research

authors： Pralong D,Tomaskovic-Crook E,Opeskin K,Copolov D,Dean B

更新日期：2000-07-07 00:00:00

abstract：:In view of prior reports suggesting associations between polymorphisms of the tumor necrosis factor gene (TNF) and schizophrenia, we sequenced all exons, introns and 7 kb flanking sequence at TNF in DNA pooled from 125 Caucasian schizophrenia cases and 200 controls. We identified 18 SNPs of which we selected and genot...

journal_title：Schizophrenia research

authors： Shirts BH,Bamne M,Kim JJ,Talkowski M,Wood J,Yolken R,Nimgaonkar VL

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:High rates of tobacco smoking and smoking cessation failure in schizophrenia may be related to prefrontal cortical dysfunction. Novel treatment options for tobacco use disorder are needed given the limited efficacy of current pharmacotherapies. Preliminary evidence suggests high-frequency repetitive transcra...

journal_title：Schizophrenia research

authors： Kozak K,Sharif-Razi M,Morozova M,Gaudette EV,Barr MS,Daskalakis ZJ,Blumberger DM,George TP

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:Research participants must have adequate consent-related abilities to provide informed consent at the time of study enrollment. We sought to determine if research participants with schizophrenia maintain adequate consent-related abilities during a longitudinal study. If participants lose abilities during a tr...

journal_title：Schizophrenia research

authors： Stroup TS,Appelbaum PS,Gu H,Hays S,Swartz MS,Keefe RS,Kim SY,Manschreck TC,Boshes RA,McEvoy JP,Lieberman JA

更新日期：2011-08-01 00:00:00

abstract：:The immune hypothesis of schizophrenia has gained significant popularity in recent years in schizophrenia research. Evidence suggests that the peripheral immune system communicates with central nervous system and the effect propagates through microglial and lymphocyte crosstalk, especially during neuro-inflammation. A...

journal_title：Schizophrenia research

authors： Varun CN,Venkataswamy MM,Ravikumar R,Nagaraju R,Debnath M,Varambally S,Venkatasubramanian G,Ravi V

更新日期：2019-10-01 00:00:00

abstract：:This study assessed visuospatial attention in healthy adults and medicated schizophrenic patients. Participants performed a visual orientation task in which a peripheral cue was followed. at different intervals, by a target presented either at valid or invalid locations. When the long stimulus onset asynchrony (SOA) w...

journal_title：Schizophrenia research

authors： Fuentes LJ,Boucart M,Alvarez R,Vivas AB,Zimmerman MA

更新日期：1999-11-09 00:00:00

abstract：BACKGROUND:People from culturally and linguistically diverse (CALD) backgrounds are over-represented in compulsory admissions to hospital but little is known about whether this also applies to community treatment orders (CTOs). AIMS:We investigated any differences between Australian- and foreign-born patients in the l...

journal_title：Schizophrenia research

authors： Kisely S,Xiao J

更新日期：2018-07-01 00:00:00

abstract：:Frontal lobe dysfunction in individuals with schizophrenia has frequently been detected using both neuroimaging and neuropsychological testing. Results from previous studies vary in the findings of regional specificity vs. generalized frontal cortical dysfunction. We sought to examine potential regional differences in...

journal_title：Schizophrenia research

authors： Ritter LM,Meador-Woodruff JH,Dalack GW

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Little is known about the effects of antipsychotic medications on gray matter (GM) in schizophrenia. Although clozapine remains the most effective antipsychotic medication in treatment-refractory cases, it is unknown whether it has a differential effect on GM development. METHODS:In an exploratory analysis,...

journal_title：Schizophrenia research

authors： Mattai A,Chavez A,Greenstein D,Clasen L,Bakalar J,Stidd R,Rapoport J,Gogtay N

更新日期：2010-01-01 00:00:00

abstract：:There is conflicting evidence of a relationship between changes in symptoms and cognitive functioning in schizophrenia. This study investigated longitudinal changes in psychopathology and cognitive functioning in chronic schizophrenia utilising three different dimensional models of symptomatology. Sixty-two patients d...

journal_title：Schizophrenia research

authors： Hughes C,Kumari V,Soni W,Das M,Binneman B,Drozd S,O'Neil S,Mathew V,Sharma T

更新日期：2003-02-01 00:00:00

abstract：:Two reaction time (RT) paradigms were used to study clozapine's effects on sustained and selective attention compared to fluphenazine and placebo in 25 chronic schizophrenic patients. Sensory dominance was studied via simple and choice RTs to lights and tones, and on double-stimulus trials in which the two stimuli wer...

journal_title：Schizophrenia research

authors： Zahn TP,Pickar D,Haier RJ

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:The main goal of the present study was to analyze levels of cytokines of the interleukin family (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8 and IL-10), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (MCP1), tumor necrosis factor-alpha (TNF-α), and vascular endothelial and endothelial growth factors (V...

journal_title：Schizophrenia research

authors： Haring L,Koido K,Vasar V,Leping V,Zilmer K,Zilmer M,Vasar E

更新日期：2015-12-01 00:00:00

abstract：:The SELENBP1 gene previously was found to be up-regulated in microarray analysis of both peripheral blood cell and brain tissue samples from schizophrenia patients. Quantitative PCR analysis subsequently corroborated the altered expression of SELENBP1 in schizophrenia brain tissue samples from the Stanley Array Correc...

journal_title：Schizophrenia research

authors： Kanazawa T,Glatt SJ,Faraone SV,Hwu HG,Yoneda H,Tsuang MT

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Patients with schizophrenia show deviances in their dermatoglyphics, in particular reductions in palmar a-b ridge counts (ABRCs), which are evidence of an early developmental deviance. However, the severity or the origin of these ABRC changes has not been established. METHOD:(i) We examined the published li...

journal_title：Schizophrenia research

authors： Bramon E,Walshe M,McDonald C,Martín B,Toulopoulou T,Wickham H,van Os J,Fearon P,Sham PC,Fañanás L,Murray RM

更新日期：2005-06-15 00:00:00

abstract：:Second generation antipsychotics cause derangements in glucose metabolism that are often interpreted as insulin resistance. In previous studies we have shown that this is not classical insulin resistance but the drugs were actually inducing a hyperglycaemic state associated with elevated hepatic glucose output (HGO) a...

journal_title：Schizophrenia research

authors： Smith GC,Zhang ZY,Mulvey T,Petersen N,Lach S,Xiu P,Phillips A,Han W,Wang MW,Shepherd PR

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Previous studies have found increased prolactin concentrations in antipsychotic-naïve patients with schizophrenia. However, the roles of other hormones, and of potentially confounding variables such as gender and smoking, have not been considered. METHODS:Blood from newly diagnosed, antipsychotic-naïve pati...

journal_title：Schizophrenia research

authors： Garcia-Rizo C,Fernandez-Egea E,Oliveira C,Justicia A,Parellada E,Bernardo M,Kirkpatrick B

更新日期：2012-01-01 00:00:00

abstract：:An absent response to the niacin skin test has been reported to occur in about 80% of schizophrenic patients, as compared to 20% of healthy individuals. Niacin provokes redness in skin caused by a capillary vasodilatation mediated by prostaglandins. The metabolism of prostaglandins is regulated by the enzyme phospholi...

journal_title：Schizophrenia research

authors： Tavares H,Yacubian J,Talib LL,Barbosa NR,Gattaz WF

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:Gender differences in psychotic disorder have been observed in terms of illness onset and course; however, past research has been limited by inconsistencies between studies and the lack of epidemiological representative of samples assessed. Thus, the aim of this study was to elucidate gender differences in a...

journal_title：Schizophrenia research

authors： Cotton SM,Lambert M,Schimmelmann BG,Foley DL,Morley KI,McGorry PD,Conus P

更新日期：2009-10-01 00:00:00