Depression of involuntary activity in muscles paralyzed by spinal cord injury.

Abstract:

:Involuntary muscle contractions are common after spinal cord injury (SCI). Increased sensitivity to Ia muscle afferent input may contribute to the development of these spasms. Since tendon vibration results in a period of postactivation depression of the Ia synapse, we sought to determine whether Achilles tendon vibration (80 HZ for 2 s) altered involuntary contractions evoked by superficial peroneal nerve (SPN) stimulation (5 pulses at 300 HZ) in paralyzed leg muscles of subjects with chronic (>1 year) SCI. Responses to SPN stimulation that were conditioned by vibration were reduced in 66% of trials (by 33+/-12% in tibialis anterior and 40+/-16% in soleus). These reductions in electromyographic activity are unlikely to be mediated by changes at the Ia synapse or motoneuron because vibration did not alter the magnitude of the soleus H reflex. The electromyographic reductions may involve long-lasting neuromodulatory effects on spinal inhibitory interneurons or synapses involved in the flexor reflex pathway. Vibration-evoked depression of electromyographic activity may be clinically useful in controlling involuntary muscle contractions after SCI.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Butler JE,Godfrey S,Thomas CK

doi

10.1002/mus.20500

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

637-44

issue

5

eissn

0148-639X

issn

1097-4598

journal_volume

33

pub_type

杂志文章
  • Revised statistical motor unit number estimation in the Celecoxib/ALS trial.

    abstract::Techniques to estimate motor unit number (MUNE) measure the number of functioning motor units in a muscle. As amyotrophic lateral sclerosis (ALS) is characterized by progressive motor unit loss, this disease offers an ideal setting for the use of MUNE. Statistical MUNE was employed in a recent multicenter trial of cre...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20671

    authors: Shefner JM,Cudkowicz ME,Zhang H,Schoenfeld D,Jillapalli D,Northeast ALS Consortium.

    更新日期:2007-02-01 00:00:00

  • Exon 17 skipping in CLCN1 leads to recessive myotonia congenita.

    abstract::Mutations in CLCN1, the gene encoding the ClC-1 chloride channel in skeletal muscle, lead to myotonia congenita. The effects on the intramembranous channel forming domains have been investigated more than that at the intracellular C-terminus. We have performed a mutation screen involving the whole CLCN1 gene of patien...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20005

    authors: Chen L,Schaerer M,Lu ZH,Lang D,Joncourt F,Weis J,Fritschi J,Kappeler L,Gallati S,Sigel E,Burgunder JM

    更新日期:2004-05-01 00:00:00

  • Adolescent spinal muscular atrophy with calf hypertrophy and a deletion in the SMN gene.

    abstract::Spinal muscular atrophy (SMA) is generally associated with proximal weakness and muscle wasting. An X-linked variant with calf hypertrophy has been reported. We describe a young man with SMA type 4 with prominent calf hypertrophy in whom DNA analysis showed a homozygous deletion of exons 7 and 8 in the telomeric copy ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21013

    authors: Yiu EM,Ravat S,Ryan MM,Shield LK,Smith LJ,Kornberg AJ

    更新日期:2008-07-01 00:00:00

  • Diphtheritic neuropathy.

    abstract::A 29-year-old Haitian man had a sore throat with a marked tonsillar exudate followed by the onset of increasingly blurred vision with swallowing difficulties and, then, a diffuse acute demyelinating neuropathy. Cerebrospinal fluid showed moderate pleiocytosis and elevated protein content. Serological testing for dipht...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880181217

    authors: Créange A,Meyrignac C,Roualdes B,Degos JD,Gherardi RK

    更新日期:1995-12-01 00:00:00

  • Physiological cross-sectional area of the oblique head of the adductor pollicis is greater than its transverse counterpart: implications for functional testing.

    abstract:INTRODUCTION:Despite structural distinction between the transverse and oblique heads of the adductor pollicis, in vivo testing continues to consider the adductor pollicis as functionally simplistic. As a muscle's architecture is a strong indicator of function, in this study we aimed to determine whether the physiologic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23933

    authors: Stamenkovic A,Munro BJ,Peoples GE

    更新日期:2014-03-01 00:00:00

  • A new stain for quantitative measurement of sprouting at neuromuscular junctions.

    abstract::A new combined stain for the simultaneous demonstration of motor nerve terminals and cholinesterase at neuromuscular junctions is described. It employs bromoindoxyl acetate dye-staining for cholinesterase and silver-gold impregnation for nerve terminals. The clarity and reliability of the stain permit quantitative mea...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880010110

    authors: Pestronk A,Drachman DB

    更新日期:1978-01-01 00:00:00

  • Botulinum toxin improves sialorrhea and quality of living in bulbar amyotrophic lateral sclerosis.

    abstract::Sialorrhea is frequently a socially disabling symptom in patients with bulbar amyotrophic lateral sclerosis (ALS). In this open-label prospective study, we report the effect of botulinum toxin A (Botox) injection into the parotid glands in 10 patients with bulbar ALS and socially disabling sialorrhea. We applied three...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.20545

    authors: Verma A,Steele J

    更新日期:2006-08-01 00:00:00

  • Peripheral neuropathy in glycogen storage disease type III: Fact or myth?

    abstract:INTRODUCTION:The aim of this study was to assess whether peripheral neuropathy is a feature of glycogen storage disease type IIIa (GSD IIIa) in adult patients. METHODS:Medical records of a cohort of adult GSD IIIa patients who underwent electromyography (EMG) and nerve conduction studies (NCS) were reviewed, and the r...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24977

    authors: Herlin B,Laforět P,Labrune P,Fournier E,Stojkovic T

    更新日期:2016-02-01 00:00:00

  • Current perception threshold testing in Fabry's disease.

    abstract::We investigated 16 patients with Fabry's disease (eight hemizygous men and eight heterozygous women) in one family. We used constant current perception threshold (CPT) testing, which evaluated three major sensory nerve fiber populations, to assess subjective complaints of pain and paresthesias. We also examined clinic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199911)22:11<1531::aid-mus

    authors: Ro LS,Chen ST,Tang LM,Hsu WC,Chang HS,Huang CC

    更新日期:1999-11-01 00:00:00

  • Electrophysiological diagnosis of interdigital neuropathy of the foot.

    abstract::We have devised a method of sensory nerve conduction in the interdigital nerves of the foot using the near-nerve needle and signal averaging techniques. In 40 normal controls between the ages of 20 and 59, there was no difficulty in recording sensory compound nerve action potential (CNAP) in the various interdigital n...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880070306

    authors: Oh SJ,Kim HS,Ahmad BK

    更新日期:1984-03-01 00:00:00

  • Reference jitter values for concentric needle electrodes in voluntarily activated extensor digitorum communis and orbicularis oculi muscles.

    abstract::The aim of this study was to estimate normal jitter in voluntarily activated extensor digitorum communis (EDC) and orbicularis oculi (OOc) muscles using a disposable concentric needle electrode (CNE). The EDC of 67 normal subjects (22 males and 45 females, mean age 35.5 +/- 10.2 years) and the OOc of 50 normal subject...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21043

    authors: Kouyoumdjian JA,Stålberg EV

    更新日期:2008-06-01 00:00:00

  • Immunohistochemical characterization of human masseter muscle spindles.

    abstract::An enzyme- and immunohistochemical study has been performed on human masseter muscle spindles. Antibodies selective for different myosin heavy chain (MHC) isoforms and M-band proteins (M-protein, myomesin, and MM-CK) were used. The expression of these proteins was determined in the different intrafusal fiber types. Nu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880170105

    authors: Eriksson PO,Butler-Browne GS,Thornell LE

    更新日期:1994-01-01 00:00:00

  • Repetitive nerve stimulation of facial muscles in MuSK antibody-positive myasthenia gravis.

    abstract::To better define electrophysiological abnormalities in myasthenia gravis (MG) patients with muscle-specific tyrosine kinase (MuSK) antibodies (Ab), we compared electrophysiological features of 14 MuSK Ab-positive, 73 acetylcholine receptor antibody (AChR Ab)-positive, and 22 MuSK and AChR Ab-negative (seronegative) pa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20498

    authors: Oh SJ,Hatanaka Y,Hemmi S,Young AM,Scheufele ML,Nations SP,Lu L,Claussen GC,Wolfe GI

    更新日期:2006-04-01 00:00:00

  • Differences in both inositol 1,4,5-trisphosphate mass and inositol 1,4,5-trisphosphate receptors between normal and dystrophic skeletal muscle cell lines.

    abstract::Human normal (RCMH) and Duchenne muscular dystrophy (RCDMD) cell lines, as well as newly developed normal and dystrophic murine cell lines, were used for the study of both changes in inositol 1,4,5-trisphosphate (IP3) mass and IP3 binding to receptors. Basal levels of IP3 were increased two- to threefold in dystrophic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199807)21:7<902::aid-mus8>

    authors: Liberona JL,Powell JA,Shenoi S,Petherbridge L,Caviedes R,Jaimovich E

    更新日期:1998-07-01 00:00:00

  • Aging of the human neuromuscular system.

    abstract::Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.1215

    authors: Vandervoort AA

    更新日期:2002-01-01 00:00:00

  • Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves.

    abstract::It is important to know the effects of prolonged repetitive nerve stimulation (RNS) when it is used in neurophysiological studies. RNS with up to 100 supramaximal stimuli was given to the median, ulnar, and peroneal nerves of normal subjects and the ulnar nerves of subjects with early amyotrophic lateral sclerosis (AL...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21604

    authors: Baumann F,Henderson RD,Tremayne F,Hutchinson N,McCombe PA

    更新日期:2010-06-01 00:00:00

  • Randomized, double-blind trial of mazindol in Duchenne dystrophy.

    abstract::There is evidence that growth hormone may be related to the progression of weakness in Duchenne dystrophy. We conducted a 12-month controlled trial of mazindol, a putative growth hormone secretion inhibitor, in 83 boys with Duchenne dystrophy. Muscle strength, contractures, functional ability and pulmonary function we...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/mus.880131212

    authors: Griggs RC,Moxley RT 3rd,Mendell JR,Fenichel GM,Brooke MH,Miller PJ,Mandel S,Florence J,Schierbecker J,Kaiser KK

    更新日期:1990-12-01 00:00:00

  • Subacute demyelinating polyradiculoneuropathy complicating Epstein-Barr virus infection in GATA2 haploinsufficiency.

    abstract:INTRODUCTION:Autosomal dominant haploinsufficiency of GATA2 causes monocytopenia and natural killer cell lymphopenia, resulting in predisposition to mycobacterial, fungal, and viral infections. METHODS:Herein we report on the clinical, serologic, electrophysiologic, and pathologic evaluations of a 29-year-old woman wi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25581

    authors: Kazamel M,Klein CJ,Benarroch EE,Patnaik MM,Tracy JA

    更新日期:2018-01-01 00:00:00

  • Upper limb predominant, multifocal chronic inflammatory demyelinating polyneuropathy.

    abstract::Chronic inflammatory demyelinating polyneuropathy (CIDP) presents in rare instances with focal or multifocal upper limb involvement. We reviewed the clinical and electromyographic (EMG) characteristics of 10 such patients (UL-CIDP) and compared them with patients with typical generalized CIDP (G-CIDP) and multifocal m...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-4598(199906)22:6<758::aid-mus13

    authors: Gorson KC,Ropper AH,Weinberg DH

    更新日期:1999-06-01 00:00:00

  • Spinal irradiation does not inhibit distal axonal sprouting.

    abstract::In an attempt to determine the relative importance of the nerve cell body and of the axon in initiating and controlling axonal regeneration, nerve cell bodies were irradiated and the ability of the distal axon to sprout was examined. Mice were subjected to either 25 or 50 Gray (Gy) of x-irradiation localized to the lu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110513

    authors: Pamphlett RS

    更新日期:1988-05-01 00:00:00

  • Conduction and excitability properties of peripheral nerves in end-stage liver disease.

    abstract::The pathophysiology of hepatic neuropathy is poorly understood, but membrane depolarization due to a toxic inhibition of oxidative metabolism has been proposed. We investigated the relationship between nerve excitability properties, nerve dysfunction, and liver function in 11 pretransplant patients, the majority of wh...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20765

    authors: Ng K,Lin CS,Murray NM,Burroughs AK,Bostock H

    更新日期:2007-06-01 00:00:00

  • The positive inotropic effect of epinephrine on skeletal muscle: a brief review.

    abstract::Chronic and acute administration of epinephrine or related sympathomimetic agents are typically prescribed for the treatment of clinical disorders such as hypotension, anaphylactic and allergic reactions, and bronchial asthma. In addition to its effects on these infirmaties and on carbohydrate metabolism, epinephrine ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.880121204

    authors: Williams JH,Barnes WS

    更新日期:1989-12-01 00:00:00

  • Quantitative neuromuscular ultrasound in intensive care unit-acquired weakness: A systematic review.

    abstract::Intensive care unit-acquired weakness (ICU-AW) causes significant morbidity and impairment in critically ill patients. Recent advances in neuromuscular ultrasound (NMUS) allow evaluation of neuromuscular pathology early in critical illness. Here we review application of ultrasound in ICU-AW. MEDLINE-indexed articles w...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.24728

    authors: Bunnell A,Ney J,Gellhorn A,Hough CL

    更新日期:2015-11-01 00:00:00

  • Polymyositis--an immunofluorescence study on the distribution of collagen types.

    abstract::Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880030605

    authors: Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

    更新日期:1980-11-01 00:00:00

  • Comparison of acoustic and electrical signals from erectores spinae muscles.

    abstract::Comparison was made between simultaneous recordings of the electromyogram (EMG) and acoustic myogram (AMG) signals and the torque produced by the lumbar erectores spinae muscles of three healthy subjects while they performed isometric contractions. Repeatability of each signal was studied. The AMG had a relationship t...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110409

    authors: Stokes IA,Moffroid MS,Rush S,Haugh LD

    更新日期:1988-04-01 00:00:00

  • Impact of aging on the progression of neuropathy after liver transplantation in transthyretin Val30Met amyloidosis.

    abstract:INTRODUCTION:Information related to the long-term follow-up of neuropathy in patients with familial amyloid polyneuropathy after liver transplantation is still scarce. METHODS:We describe the neuropathic features of 3 patients with the transthyretin Val30Met mutation. Each patient underwent liver transplantation at an...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23480

    authors: Koike H,Hashimoto R,Tomita M,Kawagashira Y,Iijima M,Nakamura T,Watanabe H,Kamei H,Kiuchi T,Sobue G

    更新日期:2012-12-01 00:00:00

  • Persistent and transient "conduction block" in motor neuron diseases.

    abstract::Although conduction block indicates dysfunction of peripheral nerve, it may occur in patients with clinically typical motor neuron disease. There are no universally accepted criteria to identify conduction block, so diagnosis may be difficult. In some peripheral neuropathies, conduction block persists over long period...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880160903

    authors: Lange DJ,Trojaborg W,McDonald TD,Blake DM

    更新日期:1993-09-01 00:00:00

  • Muscle does not drive persistent posttraumatic elbow contracture in a rat model.

    abstract:INTRODUCTION:Posttraumatic elbow contracture is clinically challenging because injury often disrupts multiple periarticular soft tissues. Tissue specific contribution to contracture, particularly muscle, remains poorly understood. METHODS:In this study we used a previously developed animal model of elbow contracture. ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26344

    authors: Dunham CL,Chamberlain AM,Meyer GA,Lake SP

    更新日期:2018-12-01 00:00:00

  • Comparing the function of the corticospinal system in different species: organizational differences for motor specialization?

    abstract::An appreciation of the comparative functions of the corticospinal tract is of direct relevance to the understanding of how results from animal models can advance knowledge of the human motor system and its disorders. Two critical functions of the corticospinal tract are discussed: first, the role of descending project...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.20333

    authors: Lemon RN,Griffiths J

    更新日期:2005-09-01 00:00:00

  • SEPs and CNS magnetic stimulation in syringomyelia.

    abstract::Somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) to transcranial and spinal stimulation from upper and lower limb muscles were elicited in 13 patients with syringomyelia. Seven had an associated Chiari type I anomaly. Diagnosis was confirmed by MRI. In 5 cases, SEPs and MEPs were performed bef...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880150904

    authors: Nogués MA,Pardal AM,Merello M,Miguel MA

    更新日期:1992-09-01 00:00:00