Total ascitic fluid leukocyte count for reliable exclusion of spontaneous bacterial peritonitis in patients with ascites.

Abstract:

BACKGROUND AND AIMS:The diagnosis of spontaneous bacterial peritonitis (SBP) in patients with ascites is established by definition with a polymorphonuclear (PMN) cell count in the ascitic fluid greater than 0.250 g/l determined via cytological (microscopic) examination. In this study, we correlated the automatically assessed total ascitic nucleated cell count with PMN and determined its predictive value for diagnosis of SBP. METHODS:Six hundred and eleven consecutive paracenteses of 179 patients with ascites of various aetiologies (liver cirrhosis, hepatocellular carcinoma, peritoneal carcinomatosis, and ascites of other aetiology) were studied retrospectively. RESULTS:The most reliable diagnostic cut-off level was determined for differentiation between SBP and non-SBP via receiver operating characteristics analysis. A total ascitic nucleated cell count less than 1.0 g/l is unlikely to represent SBP (negative predictive value, 95.5%). CONCLUSIONS:If ascitic fluid samples with machine-made total ascitic nucleated cell count below 1.0 g/l are not followed by additional laboratory tests, the risk of missing the diagnosis of SBP is low. Applying these criteria we would have classified 51 samples of 611 samples (20 of 179 patients) wrongly using the cut-off value of 1 g/l. On the other hand we would have spared cytologic evaluation in about 63% of paracentesis performed in our hospital. Nevertheless, to insure patient safety, standard laboratory analysis is recommended in circumstances of clinical uncertainty. Thus, patients with first manifestation of ascites should always receive cytologic examination and full diagnostic investigation to exclude other causes of ascites.

authors

Link BC,Ziske CG,Schepke M,Schmidt-Wolf IG,Sauerbruch T

doi

10.1097/00042737-200602000-00011

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

181-6

issue

2

eissn

0954-691X

issn

1473-5687

pii

00042737-200602000-00011

journal_volume

18

pub_type

杂志文章
  • Diagnosis of spontaneous bacterial peritonitis in cirrhotic patients by use of two reagent strips.

    abstract:OBJECTIVE:Spontaneous bacterial peritonitis (SBP) is one of the potentially life-threatening complications in ascitic cirrhotic patients with a mortality rate ranging between 30 and 50%. The improved survival might be explained by a more rapid diagnosis and treatment. The aim of our study was to assess the utility of t...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200406000-00011

    authors: Thévenot T,Cadranel JF,Nguyen-Khac E,Tilmant L,Tiry C,Welty S,Merzoug N

    更新日期:2004-06-01 00:00:00

  • The wide spectrum of steatohepatitis: a report of four cases and a review of the literature.

    abstract::We report on four cases displaying the wide range of aetiological risk factors (presence or absence of family history of dyslipidaemia and cryptogenic cirrhosis, from subnormal body mass index through morbid obesity, from absent through hepatotoxic alcohol consumption), laboratory test results (from subnormal through ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200410000-00015

    authors: Lonardo A,Bagni A,Tarugi P,Loria P

    更新日期:2004-10-01 00:00:00

  • Endoscopically assisted percutaneous transesophageal gastrotubing: a retrospective pilot study.

    abstract:BACKGROUND:Percutaneous transesophageal gastrotubing (PTEG) was developed as an alternative route to access the gastrointestinal tract when percutaneous endoscopic gastrostomy is contraindicated. PTEG was originally performed without endoscopy. However, endoscopy may enhance safety. MATERIALS AND METHODS:A percutaneou...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283614ae1

    authors: Murakami M,Nishino K,Takaoka Y,Murakami S,Mori K,Murakami B,Azuma M,Tanabe S,Kida M,Koizumi W

    更新日期:2013-08-01 00:00:00

  • Trends in incidence of oesophageal and stomach cancer subtypes in Europe.

    abstract:OBJECTIVE:Time trend studies in the USA have shown that the incidences of adenocarcinomas of the oesophagus and gastric cardia have risen strongly since the 1970s, whereas the incidence of squamous cell carcinomas of the oesophagus has declined. Earlier, we found that the incidence of these adenocarcinomas also rose in...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32832ca091

    authors: Steevens J,Botterweck AA,Dirx MJ,van den Brandt PA,Schouten LJ

    更新日期:2010-06-01 00:00:00

  • Endoscopic drainage in patients with malignant extrahepatic biliary obstruction: when and how.

    abstract::The question of when and how to drain a malignant biliary obstruction (MBO), both intrinsic or extrinsic, remains a controversial point among endoscopists. An important factor that influences the decision to drain an MBO or not is if the patient is a surgical candidate or not and, in the former case, if the patients m...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001752

    authors: Mangiavillano B,Papanikolaou IS,Arvanitakis M,Auriemma F,Bianchetti M,Tarantino I,Traina M,Deviere J,Repici A

    更新日期:2020-10-01 00:00:00

  • Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial.

    abstract:BACKGROUND:Recently, the serotonin antagonist ondansetron has been reported to have a positive effect on cholestasis-associated pruritus. OBJECTIVES:To study the effect of orally administered ondansetron on pruritus in chronic liver disease in a randomized, placebo-controlled, double-blind, cross-over study. METHODS:...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00042737-199810000-00010

    authors: Müller C,Pongratz S,Pidlich J,Penner E,Kaider A,Schemper M,Raderer M,Scheithauer W,Ferenci P

    更新日期:1998-10-01 00:00:00

  • Pathophysiology of duodenal ulcer disease.

    abstract::Before the discovery of Helicobacter pylori infection some 12 years ago, three major disturbances in gastric physiology had been identified in patients with duodenal ulcer disease. These abnormalities were: impaired acid inhibition of gastrin release from the antral mucosa, increased basal and stimulated acid secretio...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:

    authors: McColl KE

    更新日期:1997-04-01 00:00:00

  • Genetic susceptibility to primary biliary cirrhosis.

    abstract::Family studies suggest that genetic factors play a role in determining susceptibility to primary biliary cirrhosis (PBC). A number of polymorphic genes with small and additive effects may thus encode factors predisposing to this 'polygenic' disease. All the published data on genetic predisposition to PBC have been obt...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-199906000-00004

    authors: Agarwal K,Jones DE,Bassendine MF

    更新日期:1999-06-01 00:00:00

  • Management of rectal cancer in France in a well-defined population.

    abstract:OBJECTIVE:The aim of this study was to draw a picture of diagnostic assessment and patterns of care for rectal cancer in France using population-based registries data. METHODS:The study included a random sample of 669 cases of rectal cancers diagnosed in 2005. RESULTS:Diagnostic assessment was performed by colonoscop...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000116

    authors: Desgrippes R,Bouvier V,Delafosse P,Robaszkiewicz M,Molinié F,Trétarre B,Lepage C,Faivre J,Jooste V,Bouvier AM

    更新日期:2014-07-01 00:00:00

  • IL28B favorable genotype and ultrarapid viral response as the earliest treatment predictors of a sustained viral response in a Georgian cohort infected with the hepatitis C genotype 1.

    abstract:OBJECTIVES:The early identification of factors contributing to the successful treatment of hepatitis C infection is important for researchers and clinicians. Studies carried out on the role of an ultrarapid viral response (URVR) for the prediction of a sustained viral response (SVR) have shown its high positive predict...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328353fd11

    authors: Karchava M,Sharvadze L,Chkhartishvili N,Nelson K,Gochitashivli N,Gatserelia L,Dvali N,Dolmazashvili E,Dzigua L,Badridze N,Zhamutashvili M,Tsertsvadze T

    更新日期:2012-07-01 00:00:00

  • Antibiotics for inflammatory bowel disease: do they work?

    abstract::A growing amount of evidence indicates that the intestinal flora plays a pathogenic role in inflammatory bowel disease (IBD): hence, the use of anti-bacterial agents as ancillary treatment in patients with ulcerative colitis, or Crohn's disease. While the results with anti-tubercular agents remain inconclusive, antibi...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200502000-00003

    authors: Guslandi M

    更新日期:2005-02-01 00:00:00

  • Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis.

    abstract:OBJECTIVES:The hybrid allele of the carboxyl ester lipase gene (CEL-HYB1) is a genetic risk factor for chronic pancreatitis (CP) although the mechanism promoting disease development is largely unknown. Here, we aimed to clinically describe subjects carrying the CEL-HYB1 allele and to elucidate why the protein product i...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001963

    authors: Tjora E,Gravdal A,Engjom T,Cnop M,Johansson BB,Dimcevski GG,Molven A,Fjeld K

    更新日期:2020-10-16 00:00:00

  • Oesophageal carcinoma with humoral hypercalcaemia of malignancy and leucocytosis.

    abstract::We report a case of oesophageal carcinoma with humoral hypercalcaemia of malignancy and leucocytosis in a 66-year-old man. We also demonstrate parathyroid hormone-related protein, by immunohistology. After admission, calcitonin was administered for the hypercalcaemia but the patient died of pneumonia on the 17th day o...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:

    authors: Watanabe HA,Matsushita H,Matsui H,Ishida A,Taguchi S,Sata H,Amano N

    更新日期:1996-05-01 00:00:00

  • The Glasgow Dyspepsia Severity Score--a tool for the global measurement of dyspepsia.

    abstract:OBJECTIVE:There is currently no reliable tool for providing a global measurement of the severity of dyspepsia in patients with a variety of upper gastrointestinal disorders. We have designed a questionnaire which records frequency of symptoms, effect on routine activities, time off work, frequency of medical consultati...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199610000-00006

    authors: el-Omar EM,Banerjee S,Wirz A,McColl KE

    更新日期:1996-10-01 00:00:00

  • An assessment of open access referral for percutaneous endoscopic gastrostomy in a district general hospital.

    abstract:OBJECTIVE:To determine the indications, technical success and outcomes of open access percutaneous endoscopic gastrostomy (PEG) insertion in the district general hospital setting. DESIGN:This study was a retrospective audit of patients receiving PEG by the thread pull method from November 1998 to November 1999, follow...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200211000-00013

    authors: Fox MR,Harris AW

    更新日期:2002-11-01 00:00:00

  • Ethnic variation in colorectal cancer risk following a positive faecal occult blood test in an English bowel cancer screening programme centre.

    abstract:BACKGROUND AND AIMS:The literature on colorectal cancer (CRC) screening and ethnic diversity is dominated by studies from the USA. There are no such published data from the UK bowel cancer screening programme (BCSP) population. The Wolverhampton Bowel Cancer Screening Centre serves a population of 900,000 in the Black ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000443

    authors: Padmanabhan H,Widlak M,Nevill A,McKaig B,Brookes M,Veitch A

    更新日期:2015-11-01 00:00:00

  • Clinical utility of capsule endoscopy in patients with Crohn's disease and inflammatory bowel disease unclassified.

    abstract:BACKGROUND:Although small bowel capsule endoscopy (SBCE) has developed an established role in Crohn's disease (CD), there is paucity of data on impact of SBCE on subsequent management. We investigated the clinical utility of SBCE in patients with suspected and established CD and inflammatory bowel disease unclassified ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32835ddb85

    authors: Kalla R,McAlindon ME,Drew K,Sidhu R

    更新日期:2013-06-01 00:00:00

  • Risk factors for bleeding evaluated using the Forrest classification in Japanese patients after endoscopic submucosal dissection for early gastric neoplasm.

    abstract:BACKGROUND/AIMS:Bleeding remains a serious complication after endoscopic submucosal dissection (ESD). Second-look endoscopy for hemostasis helps prevent post-ESD bleeding. We investigated the relationships between patient characteristics, tumor characteristics, and the Forrest classification for exposed vessels on arti...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000419

    authors: Noda H,Ogasawara N,Izawa S,Ozeki T,Yanamoto K,Okaniwa N,Tanabe A,Sasaki M,Kasugai K

    更新日期:2015-09-01 00:00:00

  • Hepatic Methionine-enkephalin may interfere with response to antiviral therapy in chronic hepatitis C.

    abstract:BACKGROUND:The immunoreactivity of methionine-enkephalin (Met-enkephalin), one of the endogenous opioid peptides, is expressed in the liver in different types of chronic diseases. This finding suggests that the liver may be a source of endogenous opioids in disease state. In-vitro studies have shown that morphine, whic...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283509197

    authors: Floreani A,Antoniazzi S,Mescoli C,Bergasa NV

    更新日期:2012-04-01 00:00:00

  • Telomeres and telomerases: intimations of immortality.

    abstract::There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immortalization'. Telomeres, structures that cap the chromosomes, are related to cell longevity and are regulated by a ribonucleoprotein called telomerase. This review describe...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 评论,杂志文章

    doi:10.1097/00042737-200108000-00002

    authors: Crocker J

    更新日期:2001-08-01 00:00:00

  • Proton pump inhibitor therapy is associated with reduced survival following first-time transarterial chemoembolization in patients with hepatocellular carcinoma.

    abstract:BACKGROUND AND AIMS:Several studies have reported associations of proton pump inhibitor (PPI) treatment with the incidence of complications and even increased mortality in patients with liver cirrhosis. Up to now, there are no studies on the impact of PPI treatment in patients with hepatocellular carcinoma (HCC). There...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000002018

    authors: Sturm L,Muller L,Schultheiss M,Binder B,Huber JP,Thimme R,Bettinger D

    更新日期:2020-12-14 00:00:00

  • Screening esophagus during routine ultrasound: medical and cost benefits.

    abstract:OBJECTIVE:Cost-effectiveness analysis is an approach used to determine the value of a medical care option and refers to a method used to assess the costs and health benefits of an intervention. Upon the diagnosis of liver cirrhosis, the current guidelines recommend that all cirrhotic patients have to be screened for th...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000196

    authors: Abd Elrazek AE,Eid KA,El-Sherif AE,Abd El Al UM,El-Sherbiny SM,Bilasy SE

    更新日期:2015-01-01 00:00:00

  • Can biochemical markers be used to screen patients with inflammatory bowel disease for osteoporosis?

    abstract::Reduced bone mineral density has been reported in patients with inflammatory bowel disease and recent studies indicate that there is also an increase in the relative risk of fracture. Absolute risk of fracture is, however, generally low and thus measurement of bone mineral density as a screening procedure for all pati...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 评论,社论

    doi:10.1097/00042737-200206000-00001

    authors: Compston JE

    更新日期:2002-06-01 00:00:00

  • Noninvasive assessment of pediatric inflammatory bowel disease with ¹⁸F-fluorodeoxyglucose-positron emission tomography and computed tomography.

    abstract:OBJECTIVES:¹⁸F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) is a less invasive diagnostic tool and promising in detecting gastrointestinal lesions of pediatric inflammatory bowel disease (IBD) patients. Co-registration of low-dose computed tomography (CT) could lead to improvements in the assessment of d...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283410222

    authors: Däbritz J,Jasper N,Loeffler M,Weckesser M,Foell D

    更新日期:2011-01-01 00:00:00

  • The association of nonalcoholic fatty liver disease with genetic polymorphisms: a multicenter study.

    abstract:INTRODUCTION:Growing evidence suggests that multiple factors, such as insulin resistance, nutritional factors, gut microbiota, and hormones released from the adipose tissue, act together on genetically predisposed individuals. We aimed to investigate whether various single-nucleotide polymorphisms (SNPs) play a role in...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0000000000000813

    authors: Uygun A,Ozturk K,Demirci H,Oztuna A,Eren F,Kozan S,Yilmaz Y,Kurt O,Turker T,Vatansever S,Alper E,Unsal B

    更新日期:2017-04-01 00:00:00

  • Leukotriene receptor antagonism in experimental acute pancreatitis in rats.

    abstract:OBJECTIVES:Acute pancreatitis is a multifactorial disease caused by activation of several inflammatory mediators. Leukotrienes, beside other mediators, may be involved in acute pancreatitis. The aim of this study was to investigate the effects of 'zafirlukast', a leukotriene receptor antagonist, in acute pancreatitis a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200404000-00003

    authors: Oruc N,Yukselen V,Ozutemiz AO,Yuce G,Celik HA,Musoglu A,Batur Y

    更新日期:2004-04-01 00:00:00

  • Zooming in on Barrett oesophagus using narrow-band imaging: an international observer agreement study.

    abstract:BACKGROUND:Several classifications of mucosal morphology have been proposed in Barrett oesophagus using narrow-band imaging (NBI). We evaluated a simplified classification in which only the regularity of mucosal and vascular patterns were evaluated. AIM:To assess the inter and intraobserver agreement and the correlati...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e3283271e87

    authors: Alvarez Herrero L,Curvers WL,Bansal A,Wani S,Kara M,Schenk E,Schoon EJ,Lynch CR,Rastogi A,Pondugula K,Weusten B,Sharma P,Bergman JJ

    更新日期:2009-09-01 00:00:00

  • Effect of nicotine on large bowel mucus thickness, eicosanoids and faecal proteinase in ferrets.

    abstract:BACKGROUND:Following observations on the effect of subcutaneous nicotine on rectal mucosal eicosanoids and mucus in the rabbit we have repeated the work in ferrets which may be a more suitable animal model. AIMS AND METHODS:The effect of nicotine on mucosal eicosanoids, the adherent mucus layer, and faecal proteinases...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199702000-00013

    authors: Thomas GA,Pullan RD,Zijlstra FJ,Rankin BJ,Russell MA,Feyerabend C,Allen A,Rhodes J

    更新日期:1997-02-01 00:00:00

  • Endoscopic therapy + β-blocker vs. covered transjugular intrahepatic portosystemic shunt for prevention of variceal rebleeding in cirrhotic patients with hepatic venous pressure gradient ≥16 mmHg.

    abstract:BACKGROUND AND OBJECTIVE:Currently, monitoring hepatic venous pressure gradient (HVPG) have been proved to be the best predictor for the risk of variceal bleeding. We performed the study to evaluate the effect of endoscopic therapy + β-blocker vs. covered transjugular intrahepatic portosystemic shunt (TIPS) for the pre...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001872

    authors: Guo H,Zhang F,Yin X,Zhang M,Xiao J,Wang Y,Zhang B,Zhang W,Zou X,Zhuge Y

    更新日期:2020-08-28 00:00:00

  • Celiac disease and Budd Chiari syndrome: report of a case with review of literature.

    abstract::We here report a case of celiac disease and Budd Chiari syndrome. This 19-year-old boy was diagnosed to have portal hypertension in another hospital when he had developed variceal bleeding. In our hospital, he was found to have occlusion of all three hepatic veins as the cause of portal hypertension. On a routine endo...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/MEG.0b013e328328f47f

    authors: Kochhar R,Masoodi I,Dutta U,Singhal M,Miglani A,Singh P,Singh K

    更新日期:2009-09-01 00:00:00