Abstract:
:The risk of cardiovascular events in patients with diabetes is similar to that of patients with previous history of ischaemic heart disease and the prevalence of ischaemic heart disease complicating diabetic syndromes is growing rapidly. Management of ischaemic heart disease in diabetic patients remains a challenge. Therapeutic options include several antianginal agents, and mechanical removal of coronary obstructions by percutaneous transluminal coronary angioplasty, and aorto-coronary by-pass surgery. Unfortunately, all treatments are less effective in diabetic patients than in nondiabetic patients. Direct modulation of cardiac metabolic alterations associated with the diabetic syndrome appears as a promising alternative for the management of ischaemic heart disease in diabetic patients. Results obtained in anginal patients with the metabolic agent trimetazidine are consistent with this hypothesis.
journal_name
Coron Artery Disjournal_title
Coronary artery diseaseauthors
Marzilli M,Affinito Sdoi
10.1097/00019501-200511001-00005subject
Has Abstractpub_date
2005-11-01 00:00:00pages
S23-7eissn
0954-6928issn
1473-5830pii
00019501-200511001-00005journal_volume
16 Suppl 1pub_type
杂志文章,评审abstract:BACKGROUND:The role of thrombolytic therapy (TT) and percutaneous coronary interventions (PCIs) in subgroups of patients with right ventricular infarction (RVI) has not been evaluated. METHODS AND RESULTS:We risk-stratified 302 patients with RVI into three subsets upon admission. Class A (n=197) comprised patients wit...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200202000-00008
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:As the endothelium and inflammatory cells play a crucial role in the development of collaterals after a sudden or slowly progressing stenosis of coronary arteries, the levels of soluble endothelial adhesion molecules (CAMs) including vascular cell adhesion molecule (VCAM-1) intercellular adhesion molecule-1 (...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200411000-00008
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Spinal cord stimulation (SCS) is effective in the treatment of severe coronary artery disease (CAD) unresponsive to anti-anginal medication or revascularization procedures. However, there is still concern about its safety. OBJECTIVE:To investigate the reliability, morbidity, and mortality aspects of SCS in ...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199701000-00005
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the procedural characteristics, myocardial perfusion, and long-term outcomes in ST-elevation myocardial infarction patients with an ectatic infarct-related artery (IRA). PATIENTS AND METHODS:The retrospective analysis included 1270 consecutive ST-elevation myocardial inf...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000720
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Studies on the relationship between coronary artery calcium and aortic diameter are scarce. The aim of the current study was to evaluate the correlation between coronary artery calcium score (CACS) and maximal thoracic and abdominal aortic diameters in a population of elderly (>65 years) male hypertensive pa...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000150
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To investigate the predictive value of the PRECISE-DAPT score for the development of arrhythmias in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. METHOD:A total of 706 patients with a diagnosis of ST-segment elevation myocardial infarction who...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000788
更新日期:2019-11-01 00:00:00
abstract:AIMS:Uric acid (UA) has been associated with the presence and severity of coronary artery disease. To further assess the role of UA role in coronary artery disease, we investigated UA levels in both healthy asymptomatic middle-aged individuals and in different subgroups of hospitalized patients with suspected or defini...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000593
更新日期:2018-05-01 00:00:00
abstract:AIM:The purpose of this study was a head-to-head comparison of tomographic imaging (SPECT) with technetium-99m (Tc-99m)-sestamibi and thallium-201 (Tl-201) using dipyridamole-low-level bicycle exercise stress for the assessment of coronary artery disease. METHODS:We studied 38 consecutive patients referred for the eva...
journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Elderly patients with ischaemic heart disease are often treated more conservatively and for longer than younger patients, but this strategy may result in subsequent invasive intervention of more advanced and higher risk coronary disease. METHODS:We performed a retrospective analysis of 109 patients aged > o...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199711000-00006
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:Drug-coated balloon (DCB) angioplasty has emerged as an effective management strategy worldwide. In June 2016, DCB became available for the treatment of de novo small coronary lesions in Japan; however, there has been no multicenter analysis in a post-approval real-world clinical setting to date. The aim of t...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000782
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Women have been considered to be at higher risk of complications relating to percutaneous transluminal coronary angioplasty (PTCA) than are men. One reason for this sex-related difference could be the ischemic response of myocardium during the procedure. OBJECTIVE:To investigate whether there are sex-relate...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200010000-00003
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:Free-radical generation after successful thrombolysis in acute myocardial infarction may jeopardize ischaemic but viable myocardium, thus limiting the optimal benefits of reperfusion. METHODS:Circulating free-radical activity was assessed in 25 consecutive patients with acute myocardial infarction. Those wh...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199309000-00003
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:ABO blood groups have been associated with venous thromboembolism and arterial thrombosis. Although platelets play key roles in thrombogenesis, the relation between ABO groups and platelets is not well known and was investigated in this study. PATIENTS AND METHODS:ABO blood type information was retrospectiv...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000676
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Second-generation drug-eluting stents (DES) have been used widely to treat DES in-stent restenosis (ISR), which remains a clinical challenge. Knowledge of the outcomes of repeated second-generation DES implantation for focal versus nonfocal-type ISR is still missing. METHODS:In the current study, 254 patien...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000283
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND AIM:The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter ...
journal_title:Coronary artery disease
pub_type: 杂志文章,多中心研究
doi:10.1097/MCA.0000000000000546
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Carotid intima-media thickness (CIMT) is regarded as a controversial risk marker for cardiovascular disease (CVD). We aimed to evaluate the role of CIMT and carotid plaque progression as predictors for the progression of coronary plaque and compositions. METHODS:In the Garlic 4 study, asymptomatic patients ...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000001001
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Apoptotic cell death is the major form of myocardial damage produced by coronary ischemic events. OBJECTIVE:To assess whether circulating levels of soluble Fas (sFas), an inhibitor of apoptosis, and sFas ligand, an inducer of apoptosis, in patients with coronary artery disease are greater than normal. METH...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199906000-00003
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVES:Recent studies have reported a strong independent association between increased red cell distribution width (RDW) and the risk of adverse outcomes in patients with heart failure, stable coronary disease, and acute coronary syndromes. However, in this study we aimed to determine the impact of an elevated RDW ...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283587897
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:Although underlying mechanisms of coronary artery ectasia (CAE) are clearly unknown, destruction of extracellular matrix may be responsible for the ectasia formation. Thus, we investigated the role of matrix metalloproteinases (MMP), tissue inhibitor of matrix metalloproteinases (TIMP-1), and inflammatory mar...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283109079
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate whether chronotropic incompetence (CI), the inability to reach 85% of the maximal predicted heart rate during exercise, affects the assessment of myocardial ischemia and prognosis in patients undergoing myocardial perfusion single-photon emission computed tomography (MPS)...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000064
更新日期:2014-03-01 00:00:00
abstract::Optical coherence tomography (OCT) is the current state-of-the-art intracoronary imaging modality that allows visualization of detailed morphological characteristics of both atherosclerotic plaque and stent. So far, three expert review documents have been released for standardization of OCT image analysis. In the real...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/MCA.0000000000000072
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Endothelial dysfunction is a key step in the initiation and progression of atherosclerosis and subsequent cardiovascular complications. We examined whether peripheral endothelial function, as assessed by fingertip reactive hyperemia-peripheral arterial tonometry (RH-PAT), can provide additional clinical valu...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000208
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Although atherosclerosis is supposed to be responsible for more than 50% of coronary artery ectasia, the precise pathology of coronary artery ectasia is not clearly understood. A histopathological examination of ectatic segments has revealed mainly destruction of the media layer of the artery. In the present...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200512000-00007
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Coronary heart disease is a major cause of morbidity and mortality in the elderly, a rapidly growing section of the population. Elderly patients have been excluded from most preventative risk factor trials. METHODS:We evaluated fluvastatin, a fully synthetic hydroxymethyl glutaryl coenzyme A reductase inhib...
journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1998-01-01 00:00:00
abstract::Potentially hazardous short ischemic episodes increase the tolerance of myocardium to ischemia paradoxically. This condition decreases the infarct area markedly caused by a longer duration of coronary occlusion. This phenomenon is known as 'ischemic preconditioning' and its powerful cardioprotective effect has been sh...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-200605000-00013
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:The transradial approach has gained increasing popularity for elective percutaneous coronary intervention. However, the safety and feasibility of transradial coronary intervention (TRI) in acute myocardial infarction (AMI) remains uncertain. Hence, a meta-analysis of randomized trials was performed to compar...
journal_title:Coronary artery disease
pub_type: 杂志文章,meta分析
doi:10.1097/MCA.0b013e3283526a9d
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Coronary artery bypass grafting has been performed for a long period utilizing saphenous vein grafts, the fate of which might be crucial to prognosis following the operation. Metabolic syndrome, on the other hand, has become an increasingly important part of cardiovascular practice. We examined whether there...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200602000-00007
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Following percutaneous transluminal coronary angioplasty (PTCA), the extent of vascular injury is underestimated by angiographic assessment. Conventional intracoronary ultrasound (ICUS) imaging provides additional information with regard to the extent of dissections but requires mental reconstruction of cons...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/01.mca.0000064020.05024.e5
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study is to determine the prevalence of coronary artery ectasia and its relationship to atheromatous changes in participants undergoing coronary computed tomography angiography. BACKGROUND:Coronary artery ectasia occasionally encountered on conventional coronary angiography is considered a m...
journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章
doi:10.1097/MCA.0b013e3280144be1
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Electrogram fractionation can result when multiple groups of cardiac cells are excited asynchronously within the recording region of a mapping electrode. The spatial resolution of an electrode thus plays an important role in mapping complex rhythms. METHODS:We used a computational model, validated against e...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283507a9b
更新日期:2012-03-01 00:00:00