Frozen section of thyroid and parathyroid specimens.

Abstract:

CONTEXT:Preoperative fine-needle aspiration of thyroid lesions has greatly diminished the need for surgical evaluation. However, because thyroid nodules are common lesions, many still require surgical intervention and represent a substantial number of cases that the pathologist encounters in the frozen section laboratory. OBJECTIVE:Comprehensive reviews of frozen section indications, as well as gross, cytologic, and histologic features of the most common and diagnostically important thyroid and parathyroid lesions, are presented to provide a guideline for proper triage and management of these cases in the frozen section laboratory. The most common pitfalls are discussed in an attempt to avoid discordant diagnoses. DATA SOURCES:Thyroid lobectomy, subtotal or total thyroidectomy, and parathyroid biopsy or parathyroidectomy cases are included in this review. CONCLUSIONS:The frozen section evaluation of thyroid and parathyroid lesions remains a highly accurate procedure with a low false-positive rate. Gross inspection, complemented by cytologic and histologic review, provides the surgeon with the rapid, reliable, cost-effective information necessary for optimum patient care.

journal_name

Arch Pathol Lab Med

authors

Anton RC,Wheeler TM

doi

10.1043/1543-2165(2005)129[1575:FSOTAP]2.0.CO;2

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

1575-84

issue

12

eissn

0003-9985

issn

1543-2165

pii

RA5070

journal_volume

129

pub_type

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