The circumferential resection margin in rectal carcinoma surgery.

Abstract:

:After radical resection of rectal carcinoma, the circumferential resection margin (CRM) on the non-peritonealized surface of the resected specimen is of critical importance. Histopathological examination of resected specimens must include careful assessment of the CRM. There is a need to distinguish between CRM-positive (CRM directly involved by tumor or minimal distance between tumor and CRM 1 mm or less) and CRM-negative (distance between tumor and CRM more than 1 mm) situations. Optimized surgery (so-called TME surgery) and an experienced surgeon decrease the frequency of CRM-positive specimens. The CRM status is an important predictor of local and distant recurrence as well as survival. The CRM status can be reliably predicted by preoperative thin-slice high-resolution magnetic resonance imaging (MRI). In the event of predicted CRM-positivity, neoadjuvant radiochemotherapy is indicated.

journal_name

Tech Coloproctol

authors

Hermanek P,Junginger T

doi

10.1007/s10151-005-0226-1

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

193-9; discussion 199-200

issue

3

eissn

1123-6337

issn

1128-045X

journal_volume

9

pub_type

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