Abstract:
:The presented data suggest that PAPase may, indeed, be important in the biosynthesis of lung phospholipids. The observed increase in the specific activity of rabbit lung precedes the "surge" of phosphatidylcholine concentration and surfactant biosynthesis by at least 24 hours. In human amnionic fluid, PAPase specific activity was markedly increased in pregnancies of 35 weeks of gestation or more. The increase in the specific activity of PAPase preceded the "surge" of acetone precipitated phosphatidylcholine. The reported studies may provide an additional procedure to examine the problems associated with surfactant biosynthesis.
journal_name
Chestjournal_title
Chestauthors
Johnston JM,Schultz M,Jimenez JM,MacDonald PCdoi
10.1378/chest.67.2.18ssubject
Has Abstractpub_date
1975-02-01 00:00:00pages
18S-21Sissue
2 Suppleissn
0012-3692issn
1931-3543pii
S0012-3692(15)53070-5journal_volume
67pub_type
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