Vascular development in endometriosis.

Abstract:

:Endometriosis, defined as the presence of endometrial tissue outside the uterus, is an estrogen-dependent disease which causes pelvic pain and subfertility in women of reproductive age. The condition has a dramatic impact on the professional, social and marital life of sufferers. Direct and indirect evidence suggests that angiogenesis is required for the development and persistence of endometriosis. In this review the state-of-the-art with regard to our understanding of the role of angiogenesis in the ectopic implantation and survival of menstrual endometrial tissue will be discussed.

journal_name

Angiogenesis

journal_title

Angiogenesis

authors

Groothuis PG,Nap AW,Winterhager E,Grümmer R

doi

10.1007/s10456-005-9005-x

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

147-56

issue

2

eissn

0969-6970

issn

1573-7209

journal_volume

8

pub_type

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