Abstract:
:Clear rhinorrhea is a common symptom in patients with obstructive sleep apnea (OSA) and may worsen with continuous positive airway pressure therapy. Clear rhinorrhea can also be the presenting symptom of cerebrospinal fluid (CSF) leak, which is evidence of a communication between the subarachnoid space and the nasal cavity or sinuses. While CSF leak has been reported to occur with nasal continuous positive airway pressure (nCPAP) therapy following trauma to the skull base, its association with OSA and nCPAP therapy in the absence of trauma has not been previously described. We report two patients with OSA in whom CSF leak developed following the institution of nCPAP therapy. In one patient, the rhinorrhea was complicated by meningitis. Both patients underwent successful repair of their defects. One patient successfully restarted nCPAP therapy, while the other refused it.
journal_name
Chestjournal_title
Chestauthors
Kuzniar TJ,Gruber B,Mutlu GMdoi
10.1378/chest.128.3.1882subject
Has Abstractpub_date
2005-09-01 00:00:00pages
1882-4issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(15)52230-7journal_volume
128pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:Electromagnetic navigation bronchoscopy (ENB) with biopsy under fluoroscopic guidance has enhanced the yield of flexible bronchoscopy in the diagnosis of peripheral lung lesions. However, the accuracy of ENB navigation suggests that the addition of fluoroscopy is redundant. OBJECTIVES:Data were prospectivel...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.06-3016
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Eosinophils contain granule proteins such as eosinophil cationic protein (ECP) that have proinflammatory effects on airways. ECP may be released on activation of eosinophils into the plasma and is widely used as a marker of bronchial hyperreactivity and allergic inflammation. Environmental factors as well as...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.121.4.1111
更新日期:2002-04-01 00:00:00
abstract::Endomyocardial fibrosis (EMF) is a fascinating disease entity of unknown etiology. It is prevalent in the tropical zone. Its essential features are the formation of fibrous tissue on the endocardium and to a lesser extent in the myocardium of the inflow tract and apex of one or both ventricles. It results in endocardi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.6.3985
更新日期:2005-12-01 00:00:00
abstract::To assess the prognostic significance of myocardial contractile reserve in patients with idiopathic dilated cardiomyopathy (DCM) without overt heart failure (New York Heart Association functional class I or II), seventy-one patients underwent exercise radionuclide angiography in addition to clinical, radiographic, hem...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.2.344
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2973
更新日期:2011-09-01 00:00:00
abstract:STUDY OBJECTIVES:The purpose of this study was to determine the impact of a multisite implementation of an evidence-based clinical practice guideline for bronchiolitis. DESIGN:Before and after study. SETTING:Eleven Child Health Accountability Initiative (CHAI) study hospitals. PATIENTS:Children < 12 months of age wi...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.121.6.1789
更新日期:2002-06-01 00:00:00
abstract:STUDY OBJECTIVE:Cardiopulmonary bypass (CPB) induces a generalized inflammatory response, including activation of leukocytes, contributing to postoperative morbidity. The inflammatory pathways leading to this systemic inflammatory response syndrome are considered identical to those involved in septic shock. Therefore, ...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.111.3.577
更新日期:1997-03-01 00:00:00
abstract::Cardiac tamponade is a medical emergency that can be readily reversed with timely recognition and appropriate intervention. The clinical diagnosis of cardiac tamponade requires synthesis of a constellation of otherwise nonspecific features based on an understanding of the underlying pathophysiological characteristics....
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2017.11.003
更新日期:2018-05-01 00:00:00
abstract:STUDY OBJECTIVE:To measure the ability of a set of clinical parameters, the Winthrop-University Hospital (WUH) criteria, to identify Legionella pneumonia while discriminating against bacteremic pneumococcal pneumonia at the time of hospitalization for community-acquired pneumonia (CAP). DESIGN:Retrospective case-contr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.4.1064
更新日期:2001-10-01 00:00:00
abstract::We report a case of Pasteurella multocida pneumonia and its unusual clinical presentation. We also discuss the rarity of its diagnosis by TPC specimens and the delay in both an adequate diagnosis and treatment. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.99.6.1517
更新日期:1991-06-01 00:00:00
abstract::Two recent epidemiologic case-control studies suggested that fenoterol, a selective beta-adrenergic agonist, was associated with an increase in the risk of asthma death. The results of these studies were criticized because of methodologic problems in the choice and selection of control subjects; the different methods ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.6.1586
更新日期:1991-12-01 00:00:00
abstract::We describe a patient who suffered from a bacterial pneumonia and had a left-sided infiltrate on his chest radiograph. He was found to be cytopenic and acute myeloid leukemia was diagnosed. A complete remission was achieved after chemotherapy, and the patient was scheduled to have autologous bone marrow transplantatio...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.6.1908
更新日期:1993-06-01 00:00:00
abstract::We conducted a prospective study to determine the effectiveness of protected bronchoalveolar lavage (PBAL) in diagnosing pneumonia in ventilated patients and the usefulness of bronchoscopic data in treating ventilated patients. Entrance criteria were (1) fever and a new or progressive infiltrate on chest roentgenogram...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.2.500
更新日期:1992-02-01 00:00:00
abstract::Pulmonary embolism (PE) is a common disorder that is accompanied by significant morbidity and mortality. Although anticoagulation is the standard treatment for PE, thrombolytic therapy, with its ability to produce rapid clot lysis, has long been considered an attractive alternative. Although many studies have been per...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.115.6.1695
更新日期:1999-06-01 00:00:00
abstract::A 3-month-old infant was brought to clinic for evaluation of recurrent apparent life-threatening events (ALTEs). Two ALTE episodes occurred while the infant was sleeping in a safety car seat. The first one occurred when he was 4 weeks old. His mother noticed that he was not breathing; he appeared limp with full body c...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.14-1595
更新日期:2015-04-01 00:00:00
abstract::A 31-year-old man with legionnaires' disease, who presented with severe pneumonia and hypoxemia, later developed severe bronchospasm and marked hypercapnia, a complication not previously reported in Legionella infection. He responded to therapy with erythromycin and a bronchodilator. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.82.3.382
更新日期:1982-09-01 00:00:00
abstract:PURPOSE:Stenosis and occlusion rates of internal mammary artery (IMA) and saphenous vein (SV) coronary artery bypass grafts (CABGs) are markedly different, which result from respective disparities in vascular remodeling. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulate vascu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.5.1853
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:Lung expansion techniques (LETs) are widely used to prevent postoperative pulmonary complications (PPCs). However, the effects of each of these techniques on thoracoabdominal mechanics and PPC incidence after abdominal surgery remain unclear. The objective of this study was to compare the effects of LET on pu...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.14-2696
更新日期:2015-10-01 00:00:00
abstract:STUDY OBJECTIVES:(1) To determine physician preferences in the management of warfarin-induced excessive anticoagulation (AC); and (2) to assess compliance with the American College of Chest Physicians (ACCP) guidelines for the reversal of excessive AC. DESIGN:Cross-sectional physician survey. PARTICIPANTS:Members of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.6.1972
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Long-term outcomes after stepping down asthma medications are not well described. METHODS:This study was a retrospective time-to-event analysis of individuals diagnosed with asthma who stepped down their asthma controller medications using a US claims database spanning 2000 to 2012. Four-month intervals wer...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.15-0301
更新日期:2015-09-01 00:00:00
abstract::The purpose of our study was to determine the frequency of cardiac ectopy during the performance of flow-volume loops. The performance of an adequate flow-volume loop entails significant shifts in intrathoracic pressure and oxyhemoglobin saturation that could heighten myocardial arrhythmogenicity and lead to increased...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.4.1006
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:Cytochrome P-450 2J2 (CYP2J2) has recently been shown to be an important enzyme in the metabolism of epoxygenase-derived eicosanoids that play important functional roles in pulmonary physiology and may contribute to the pathogenesis of asthma. STUDY OBJECTIVE:The focus of our pilot study was to evaluate whe...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.07-0371
更新日期:2007-07-01 00:00:00
abstract::Bilateral tuberculous pneumonia with the syndrome of inappropriate secretion of antidiuretic hormone was the cause of the adult respiratory distress syndrome in an elderly patient. Early recognition and prompt therapy enabled the patient to make a complete recovery without the necessity for mechanical ventilation. Wit...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.72.5.678
更新日期:1977-11-01 00:00:00
abstract:OBJECTIVE:To study the effect of intravenous (i.v.) terbutaline on potassium (K) and magnesium (Mg) distribution, ECG changes, and prevalence of ventricular ectopic beats in healthy subjects. DESIGN:Randomized double-blind, placebo-controlled crossover. Subjects received either placebo or terbutaline (bolus, 0.25 mg; ...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.106.6.1654
更新日期:1994-12-01 00:00:00
abstract::We describe an unusual case of orthodeoxia platypnea syndrome exacerbated by right ventricular inflow obstruction due to iatrogenic steroid-induced adipose deposition in cardiac tissues. A 68-year-old man on long-term prednisone therapy for eosinophilic pneumonia presented with progressive dyspnea worsened by bending ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-0874
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:COPD has traditionally been defined by the presence of irreversible airflow limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung Disease) or American Thoracic Society/European Respiratory Society criteria (lower limit of normal [LLN]). We have observed that some pati...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.14-1556
更新日期:2015-07-01 00:00:00
abstract::Care of ventilator-dependent patients requires considerable resources, yet the long-term outcomes of this type of care have rarely been described. We retrospectively investigated the posthospital course of elderly patients who survived an episode of prolonged ventilator dependency to describe survival rates, subsequen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.5.1120
更新日期:1989-11-01 00:00:00
abstract:STUDY OBJECTIVE:We analyze the within-subject variation of mouth occlusion pressure (P0.1) response to progressive isocapnic hypoxic stimulation over long time periods in normal subjects. PATIENTS AND INTERVENTIONS:We studied 21 healthy subjects (14 male and 7 female; aged 40+/-12 yrs) (mean+/-SD). Lung volumes, basal...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.114.2.521
更新日期:1998-08-01 00:00:00
abstract::Resection of the tricuspid valve without prosthetic replacement has successfully been performed in patients with tricuspid valvular endocarditis. Using M-mode, two-dimensional, and Doppler echocardiograms, we studied four patients who underwent tricuspid valvectomy. All patients had previous history of intravenous dru...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.5.668
更新日期:1985-05-01 00:00:00
abstract:PURPOSE:To examine the individual and joint effect of various pretreatment clinical characteristics on the survival of patients with mesothelioma treated by the Cancer and Leukemia Group B (CALGB). PATIENTS AND METHODS:Between June 1984 and September 1994, 337 patients with malignant mesothelioma and no prior chemothe...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.113.3.723
更新日期:1998-03-01 00:00:00