Rapid synthesis of DNA-cysteine conjugates for expressed protein ligation.

abstract：:The secreted isoform of fibroblast growth factor 3 (FGF3) induces a mitogenic cell response, while the nuclear form inhibits cell proliferation. Recently, we identified a nucleolar FGF3-binding protein which is implicated in processing of pre-rRNA as a possible target of nuclear FGF3 signalling. Here, we report a seco...

journal_title：Biochemical and biophysical research communications

authors： Antoine M,Reimers K,Wirz W,Gressner AM,Müller R,Kiefer P

更新日期：2005-12-16 00:00:00

abstract：:Statins confer therapeutic benefits in systemic and pulmonary vascular diseases. Bone morphogenetic protein (BMP) receptors serve essential signaling functions in cardiovascular development and skeletal morphogenesis. Mutations in BMP receptor type II (BMPR2) are associated with human familial and idiopathic pulmonary...

journal_title：Biochemical and biophysical research communications

authors： Hu H,Sung A,Zhao G,Shi L,Qiu D,Nishimura T,Kao PN

更新日期：2006-01-06 00:00:00

abstract：:The question of how eukaryotic cells assemble their mitochondria was long considered to be inaccessible to biochemical investigation. This attitude changed about fifty years ago when the powerful tools of yeast genetics, electron microscopy and molecular biology were brought to bear on this problem. The rising interes...

journal_title：Biochemical and biophysical research communications

authors： Schatz G

更新日期：2013-05-10 00:00:00

abstract：:Arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications and early death. However, the underling mechanisms of arthritis are still unclear. Sirtuins are a NAD(+)-dependent class III deacetylase family, and regulate cellular stress, inflammation, genomic stability,...

journal_title：Biochemical and biophysical research communications

authors： Lin J,Sun B,Jiang C,Hong H,Zheng Y

更新日期：2013-11-29 00:00:00

abstract：:We have identified a 35-amino acid antibiotic cecropin secreted by an established mosquito cell line. C7-10 cells from the vector mosquito, Aedes albopictus, were incubated with heat-killed Escherichia coli, and materials secreted into the cell culture supernatant were recovered by acid precipitation. Following batch ...

journal_title：Biochemical and biophysical research communications

authors： Sun D,Eccleston ED,Fallon AM

更新日期：1998-08-19 00:00:00

abstract：:Transforming growth factor beta (TGFbeta) is a critical immunosuppressive cytokine that inhibits the cell-mediated immune responses partly via inhibition of immunostimulatory cytokine production from T cells, NK cells, and macrophages. Here we investigated the effect of TGFbeta on NK cell activation induced by interle...

journal_title：Biochemical and biophysical research communications

authors： Hayashi H,Inoue Y,Tsutsui H,Okamura H,Nakanishi K,Onozaki K

更新日期：2003-01-24 00:00:00

abstract：:Histone deacetylases (HDAC) form a conserved enzyme family that control gene expression via the removal of acetyl residues from histones and other proteins and are under increasing investigation as therapeutic targets, notably in cancer and parasitic diseases. To investigate the conservation of these enzymes in the pl...

journal_title：Biochemical and biophysical research communications

authors： Oger F,Dubois F,Caby S,Noël C,Cornette J,Bertin B,Capron M,Pierce RJ

更新日期：2008-12-26 00:00:00

abstract：:To evaluate the immunomodulatory effects of histamine in vivo, we analyzed an experimental syngenic tumor model using a colon adenocarcinoma cell line, CT-26, in Balb/c mice. In this model, distinct tumor growth was observed around 6 days after inoculation. Daily administration of cimetidine (0.12 mg/kg/day) significa...

journal_title：Biochemical and biophysical research communications

authors： Takahashi K,Tanaka S,Ichikawa A

更新日期：2001-03-01 00:00:00

abstract：:Extracellular signal-regulated kinase 1 and 2 (ERK1/2) have been implicated as important regulators of metabolic homeostasis. Here we generated a new mouse model with genetic deletion of two ERK1/2 phosphatases, dual specificity phosphatase (DUSP) 6 and 8, to further define the role of ERK1/2 in obesity development. D...

journal_title：Biochemical and biophysical research communications

authors： Liu R,Peters M,Urban N,Knowlton J,Napierala T,Gabrysiak J

更新日期：2020-11-26 00:00:00

abstract：:Tumour-secreted vascular endothelial growth factor (VEGF) exerts a number of effects which are important in tumour pathology, including stimulation of angiogenesis and permeabilisation of tumour-associated vasculature. In this study we have examined the possibility that VEGF may also play an autocrine role in tumour g...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Earl HM,Baban D,Shoaibi M,Fabra A,Kerr DJ,Seymour LW

更新日期：1995-12-26 00:00:00

abstract：:The cyclin-dependent kinase (CDK) inhibitor p27(Kip1) is an important regulator of cell cycle progression as it negatively regulates G(0/1) progression and plays a major role in controlling the cell cycle. The screening of the p27(Kip1) sequence identified many potential phosphorylation sites. Although Ser(10) and Thr...

journal_title：Biochemical and biophysical research communications

authors： Guan X,Chen L,Wang J,Geng H,Chu X,Zhang Q,Du L,De W

更新日期：2006-09-01 00:00:00

abstract：:Ribosome modulation factor (RMF) is involved in stabilization of ribosomes during the transition from exponential growth to the stationary growth phase in Escherichia coli. A deficiency of RMF is known to reduce cell viability. Overaccumulation of spermidine also leads to a decrease in cell viability and to a decrease...

journal_title：Biochemical and biophysical research communications

authors： Apirakaramwong A,Fukuchi J,Kashiwagi K,Kakinuma Y,Ito E,Ishihama A,Igarashi K

更新日期：1998-10-20 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have been isolated from various tissues and used for elucidating the pathogenesis of numerous diseases. In our previous in vitro study, we showed the existence of MSCs in human spinal ligaments and hypothesized that these MSCs contributed to the pathogenesis of ossification of spinal liga...

journal_title：Biochemical and biophysical research communications

authors： Chin S,Furukawa K,Ono A,Asari T,Harada Y,Wada K,Tanaka T,Inaba W,Mizukami H,Motomura S,Yagihashi S,Ishibashi Y

更新日期：2013-07-12 00:00:00

abstract：:Epidemiological data have shown that stress and other psychological factors might influence cancer onset and progression. However, to date, the mechanisms are not well understood. In the present study, we used chronic exposure to a scream as a novel form of sound stress to explore the influence of the chronic stress b...

journal_title：Biochemical and biophysical research communications

authors： Hou N,Zhang X,Zhao L,Zhao X,Li Z,Song T,Huang C

更新日期：2013-10-04 00:00:00

abstract：:To analyze the mechanisms of mRNA export from the nucleus to the cytoplasm, we have isolated eleven mutants, ptr [poly(A)(+) RNA transport] 1 to 11, which accumulate poly(A)(+) RNA in the nucleus at a nonpermissive temperature in Schizosaccharomyces pombe. Of those, the ptr5-1 mutant shows dots- or a ring-like accumul...

journal_title：Biochemical and biophysical research communications

authors： Watanabe N,Ikeda T,Mizuki F,Tani T

更新日期：2012-02-03 00:00:00

abstract：:Xylan from Rhodymenia palmata binds to the cellobiohydrolase I from Trichoderma reesei (CBH I) or its core protein, inhibiting their activity. Adsorption onto microcrystalline cellulose (Avicel) is reduced approximately 30% for intact CBH I and nearly 50% for the core, whereas the effects with cellobiose are negligibl...

journal_title：Biochemical and biophysical research communications

authors： Abuja PM,Pilz I,Tomme P,Claeyssens M

更新日期：1989-12-15 00:00:00

abstract：:1,25-Dihydroxyvitamin D(3) [1,25(OH)(2) D(3)] exerts its biological effects by binding to the vitamin D receptor (VDR), which binds in turn to the vitamin D response elements located in the target gene's promoter. We have previously demonstrated that VDR binds in vitro with high affinity to the 5'-flanking sequence of...

journal_title：Biochemical and biophysical research communications

authors： Seoane S,Alonso M,Segura C,Pérez-Fernández R

更新日期：2002-03-22 00:00:00

abstract：:ARF-related protein 1 (ARFRP1) is a membrane-associated GTPase which inhibits the ARF/Sec7-dependent activation of phospholipase D. We have recently shown that deletion of Arfrp1 in mice results in increased apoptosis of mesodermal cells during gastrulation, leading to early embryonic lethality. Here we describe the o...

journal_title：Biochemical and biophysical research communications

authors： Mueller AG,Joost HG,Schürmann A

更新日期：2002-03-22 00:00:00

abstract：:Human platelets have been shown to contain a Ca++- and CoA-independent transacylase enzyme that catalyzes the transfer of arachidonic acid from phosphatidylcholine (PC) to lysoplasmenylethanolamine. It has been suggested that this route may represent a major source for released arachidonic acid in stimulated platelets...

journal_title：Biochemical and biophysical research communications

authors： Mahadevappa VG

更新日期：1987-04-29 00:00:00

abstract：:DNase coatings show great potential to prevent biofilm formation in various applications of the medical implant, food and marine industry. However, straightforward and quantitative methods to characterize the enzymatic activity of these coatings are currently not available. We here introduce the qDNase assay, a quanti...

journal_title：Biochemical and biophysical research communications

authors： Van der Gucht M,Aktan MK,Hendrix H,Velde GV,Paeshuyse J,Braem A,Lavigne R

更新日期：2021-01-01 00:00:00

abstract：:We report that the human 1,25-dihydroxyvitamin D3 receptor is an efficient substrate for cAMP-dependent protein kinase, in vitro. This phosphorylation reaction is rapid and neither dependent upon nor significantly affected by the presence of the 1,25-dihydroxyvitamin D3 ligand. Preliminary mapping experiments utilizin...

journal_title：Biochemical and biophysical research communications

authors： Jurutka PW,Hsieh JC,Haussler MR

更新日期：1993-03-31 00:00:00

abstract：:Accurate chromosome segregation during cell division requires that sister chromatids are kept together by cohesin complex until anaphase, when the chromatids separate and distribute to the two daughter cells. Esco2 is an acetyltransferase that is required for the establishment of sister chromatid cohesion during S pha...

journal_title：Biochemical and biophysical research communications

authors： Kim BJ,Kang KM,Jung SY,Choi HK,Seo JH,Chae JH,Cho EJ,Youn HD,Qin J,Kim ST

更新日期：2008-07-25 00:00:00

abstract：:Caveolin-1 is a major structural protein of caveolae and plays important functions in tumorigenesis and development. Hca-F and Hepa1-6 are mouse hepatocarcinoma cell lines with high and low malignant potential, respectively. Our previous studies revealed that caveolin-1 promoted cell invasion by up-regulating the glyc...

journal_title：Biochemical and biophysical research communications

authors： Yu S,Zhang L,Li N,Fan J,Liu L,Zhang J,Wang S

更新日期：2012-10-26 00:00:00

abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of authors. The Journal received an expression of concern from a reader, which noted that: “The problem is that there is no IL-26 gene in t...

journal_title：Biochemical and biophysical research communications

authors： Bao J,Lv Z,Wang S

更新日期：2018-05-23 00:00:00

abstract：:The integrity and the surface charge distribution of native low density lipoprotein (LDL) are prerequisites of its binding to the LDL receptor. Oxidation is one of the most important physiological effects resulting in an altered structure and metabolism of LDL. To reveal forces responsible for maintaining the intact s...

journal_title：Biochemical and biophysical research communications

authors： Lakatos S,Fürész J,Pállinger E,Rischák K,Schweitzer K,Szollár L

更新日期：1995-11-02 00:00:00

abstract：:The one-electron reduction product of 1-methyl-4-phenyl-2,3-dihydropyridinium ion has been generated by pulse radiolysis and its absorption spectrum recorded. This radical was found to decay by second-order kinetics (2k = 9.5 x 10(8) M-1 s-1) to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenyl-2,3-di...

journal_title：Biochemical and biophysical research communications

authors： Chacón JN,Chedekel MR,Land EJ,Truscott TG

更新日期：1989-01-16 00:00:00

abstract：:Repair of a splicing defect of β-globin pre-mRNA harboring hemoglobin E (HbE) mutation was successfully accomplished in erythroid cells from patients with β-thalassemia/HbE disorder by a synthetic splice-switching oligonucleotide (SSO). However, its application is limited by short-term effectiveness and requirement of...

journal_title：Biochemical and biophysical research communications

authors： Preedagasamzin S,Nualkaew T,Pongrujikorn T,Jinawath N,Kole R,Fucharoen S,Jearawiriyapaisarn N,Svasti S

更新日期：2018-04-30 00:00:00

abstract：:The role of recombination genes in the processing of DNA damaged by methlymethane sulfonate (MMS) was examined in an xth nth nfo strain of Escherichia coli K-12. Introduction of a recQ mutation did not increase the cell's sensitivity to MMS treatment. The presence of recF, recJ or recN mutation slightly increased the ...

journal_title：Biochemical and biophysical research communications

authors： Wang TC,Chang HY

更新日期：1991-10-31 00:00:00

abstract：:There are tremendous drug candidates that suffer from insolubility in water. In the present study, it is shown that Coenzyme Q10 (CoQ10), a model water-insoluble compound, can be nanoparticulated into a water-soluble form using apolipoprotein A-I (apoA-I). Similar to the way that apoA-I forms nascent discoidal high de...

journal_title：Biochemical and biophysical research communications

authors： Shin JY,Shin JI,Kim JS,Yang YS,Hwang Y,Yang JS,Shin D,Seo JH,Jin YS,Park YC,Hwang JS,Kweon DH

更新日期：2009-10-16 00:00:00

abstract：:Structural class characterizes the overall folding type of a protein or its domain. A number of computational methods have been proposed to predict structural class based on primary sequences; however, the accuracy of these methods is strongly affected by sequence homology. This paper proposes, an ensemble classificat...

journal_title：Biochemical and biophysical research communications

authors： Kedarisetti KD,Kurgan L,Dick S

更新日期：2006-09-29 00:00:00