Trabecular thickness measurement in cancellous bones: postmortem rat studies with the zoom-in micro-tomography technique.

Abstract:

:Using the cross-sectional images taken with the zoom-in micro-tomography technique, we measured trabecular thicknesses of femur bones in postmortem rats. Since the zoom-in micro-tomography technique is capable of high resolution imaging of a small local region inside a large subject, we were able to measure the trabecular thickness without extracting bone samples from the rats. For the zoom-in micro-tomography, we used a micro-tomography system consisting of a micro-focus x-ray source, a 1248 x 1248 flat-panel x-ray detector and a precision scan mechanism. To compensate for the limited spatial resolution in the zoom-in micro-tomography images, we used the fuzzy distance transform for the calculation of the trabecular thickness. To validate the trabecular thickness measurement with the zoom-in micro-tomography images, we compared the measurement results with those obtained from the conventional micro-tomography images of the extracted bone samples. The difference between the two types of measurement results was less than 2.5%.

journal_name

Physiol Meas

authors

Cho MH,Chun IK,Lee SC,Cho MH,Lee SY

doi

10.1088/0967-3334/26/5/008

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

667-76

issue

5

eissn

0967-3334

issn

1361-6579

pii

S0967-3334(05)93542-9

journal_volume

26

pub_type

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