Pancreatic endocrine tumor coexistent with serous microcystic adenoma: report of a case and review of the literature.


:Serous cystadenomas of the pancreas have been classified as benign exocrine tumors. There have been rare cases of malignant behavior, and in exceptional cases, coexisting neoplasms have been reported. We report a case of a coexistent neuroendocrine tumor identified within a serous cystadenoma in a 78-year-old woman, which was discovered incidentally after complete resection of the tumor. Given the unpredictable metastatic potential of neuroendocrine tumors of the pancreas, we advocate complete resection of all pancreatic cystic tumors, combined with careful sampling of the pathological specimen to rule out a coexistent potentially malignant neoplasm.


Ann Diagn Pathol


Alasio TM,Vine A,Sanchez MA,Dardik H




Has Abstract


2005-08-01 00:00:00














  • Anaplastic large cell lymphoma: another entity in the differential diagnosis of small round blue cell tumors.

    abstract::We saw in consultation a biopsy specimen from a 6-year old girl with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL). The tumor arose in soft tissue of the neck, and diagnostic tissue was obtained by core needle biopsy. Histologically, the neoplasm was cellular without pattern. Immunohi...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Gustafson S,Medeiros LJ,Kalhor N,Bueso-Ramos CE

    更新日期:2009-12-01 00:00:00

  • Measuring the dimension of invasive component in pT1 urothelial carcinoma in transurethral resection specimens can predict time to recurrence.

    abstract::Recurrences of nonmuscle-invasive urothelial bladder cancer are very common following resection. Predictive histopathologic variables in transurethral resection of bladder tumor (TURBT) specimens are of particular importance especially in determining the behavior of lamina propria-invasive tumors (high grade T1 stage)...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Hu Z,Mudaliar K,Quek ML,Paner GP,Barkan GA

    更新日期:2014-04-01 00:00:00

  • Expression of dog1 in low-grade fibromyxoid sarcoma: A study of 19 cases and review of the literature.

    abstract::DOG1 is a highly-sensitive marker often included in the immunohistochemical panel for the diagnosis of gastrointestinal stromal tumors (GISTs). Recent research has shown that DOG1 may also be expressed by low-grade fibromyxoid sarcomas (LGFMSs); this may give rise to diagnostic error when the sarcoma is located in the...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Vallejo-Benítez A,Rodríguez-Zarco E,Carrasco SP,Pereira-Gallardo S,Brugal Molina J,García-Escudero A,Robles Frías A,Marcilla D,González-Cámpora R

    更新日期:2017-10-01 00:00:00

  • Myospherulosis.

    abstract::Myospherulosis is a rare tumor caused by interaction of extravasated erythrocytes and exogenous or endogenous lipids. Fifty-nine articles presented 181 patients with myospherulosis since first description in 1969. Myospherulosis seems to occur in any age and in any part of the body; however, most frequent sites are pa...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Phillip V,Becker K,Bajbouj M,Schmid RM

    更新日期:2013-08-01 00:00:00

  • Prevalence and spectrum of T-cell lymphoproliferative disorders in patients with Hypereosinophilia: A reference laboratory experience.

    abstract::Hypereosinophilia (HE) is defined as persistently elevated absolute eosinophil count (AEC) ≥ 1.5 × 109/L, which can be due to a variety of underlying causes. In this study, we investigated the prevalence and spectrum of T-cell lymphoproliferative disorders in 124 consecutive patients with HE by flow cytometric immunop...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Shi M,Rech KL,Otteson GE,Horna P,Olteanu H,Pardanani A,Chen D,Jevremovic D

    更新日期:2020-02-01 00:00:00

  • Squamous cell carcinoma of the penis with rhabdoid features.

    abstract::A 76-year-old man presented with a tumoral lesion in his penis that had all the light microscopic and immunohistochemical features of a squamous cell carcinoma with rhabdoid phenotype. We believe that this is the fourth reported case of squamous cell carcinoma with rhabdoid features and the first one located in the pe...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Urdiales-Viedma M,Fernandez-Rodriguez A,De Haro-Muñoz T,Pichardo-Pichardo S

    更新日期:2002-12-01 00:00:00

  • Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene.

    abstract::A 34-year-old pregnant woman with bilateral kidney tumors 9.5 and 2.5 cm in maximum diameter is presented. The larger tumor was clear renal cell carcinoma. The smaller contralateral tumor was focally HMB45 positive and had unusual histomorphology, including features resembling clear renal cell carcinoma with features ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Petersson F,Michal M,Vaněček T,Hora M,Trivunic S,Halbhuber Z,Hes O

    更新日期:2011-10-01 00:00:00

  • Fine-needle aspiration cytology of giant cell tumor of soft tissue (soft tissue giant cell tumor of low malignant potential).

    abstract::Giant cell tumor of soft tissue is an uncommon neoplasm. To our knowledge, its cytopathology obtained using the fine-needle aspiration biopsy technique has not been previously described. We report an example of the fine-needle aspiration cytology of giant cell tumor of soft tissue in a 40-year-old woman, and correlate...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Beal M,Mayerson J,Wakely PE Jr

    更新日期:2003-12-01 00:00:00

  • Biphenotypic sinonasal sarcoma: A series of six cases with evaluation of role of β-catenin immunohistochemistry in differential diagnosis.

    abstract:INTRODUCTION:Biphenotypic sinonasal sarcoma (BSNS) is a recently described mesenchymal tumor exclusive to the sinonasal region. It is a low grade sarcoma, displaying evidence of myogenic and neural differentiation. Role of β-catenin immunohistochemistry in distinguishing it from its morphological mimics is not well-est...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Kakkar A,Rajeshwari M,Sakthivel P,Sharma MC,Sharma SC

    更新日期:2018-04-01 00:00:00

  • Flat elevated lesions of the colon and rectum: a spectrum of neoplastic and nonneoplastic entities.

    abstract::The aim of this prospective study is to establish the frequency and the type (neoplastic and nonneoplastic) lesions defined endoscopically as flat elevated lesion (FEL) in the colon and rectum, as well as to compare flat adenomas (FAs) to polypoid lesions of the same size with morphometric and immunohistochemical anal...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Gualco G,Reissenweber N,Cliché I,Bacchi CE

    更新日期:2006-12-01 00:00:00

  • Acute respiratory distress syndrome and blastomycosis: presentation of nine cases and review of the literature.

    abstract::Mississippi has the highest prevalence of blastomycosis in the country. In 20 years and 5 months there were 123 patients treated for blastomycosis at the University of Mississippi Medical Center. Among these, 107 patients had lung involvement and nine patients (8.4%) developed acute respiratory distress syndrome. Seve...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Lemos LB,Baliga M,Guo M

    更新日期:2001-02-01 00:00:00

  • Core needle biopsy of benign, borderline and in-situ problematic lesions of the breast: Diagnosis, differential diagnosis and immunohistochemistry.

    abstract::Core needle biopsy (CNB) is the most common sampling technique for the histologic evaluation of breast abnormalities. Diagnosing benign proliferative, borderline and some in-situ lesions in CNB is challenging and subject to a significant degree of interobserver variability. In addition, due to the inherent limitations...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Rosa M,Agosto-Arroyo E

    更新日期:2019-12-01 00:00:00

  • Observer reliability in assessment of mitotic activity and MIB-1-determined proliferation rate in pediatric sarcomas.

    abstract::In hematoxylin-eosin-stained sections of 20 pediatric sarcomas the mitotic index was assessed by four experienced pathologists and four less-experienced observers without prior instructions. In adjacent sections immunolabeled for MIB-1, the proliferation index was assessed as the estimated percentage of labeled cells ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Molenaar WM,Plaat BE,Berends ER,te Meerman GJ

    更新日期:2000-08-01 00:00:00

  • Brain in the middle ear or nasal cavity: heterotopia or encephalocele?

    abstract::Brain in the middle ear or nasal cavity: heterotopia or encephalocele? The answer to this question is greatly influenced by clinical information. Sometimes, however, this information is insufficient and the pathologist's opinion may influence patient management. It seems that most pathologists tend to get the answer w...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Heffner DK

    更新日期:2004-08-01 00:00:00

  • Intraductal tubular neoplasms of the pancreas: an overview.

    abstract::Intraductal lesions of the pancreas are an uncommon but increasingly recognized group of entities mainly because of advances in imaging technology. In the past, precise categorization and understanding of true pancreatic intraduct neoplasms were hampered not only by their relative rarity but also because of the pletho...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Chelliah A,Kalimuthu S,Chetty R

    更新日期:2016-10-01 00:00:00

  • Immunoexpression of p53 in cutaneous and subcutaneous leiomyosarcomas.

    abstract::The diagnosis of malignancy in cutaneous and subcutaneous smooth muscle tumors is based on subtle criteria. Therefore, any ancillary technique useful in this differential diagnosis is always welcome. In this report, we study the immunoexpression of p53 in 19 malignant smooth muscle tumors of the skin (15 cutaneous lei...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Fernandez-Flores A,Monteagudo C

    更新日期:2016-10-01 00:00:00

  • PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature.

    abstract:BACKGROUND AND AIMS:Programmed death ligand 1 (PD-L1), an immune check point inhibitor, is known to be expressed in several malignancies and is being considered as a prognostic factor and a potential immunotherapeutic target. The aim of this study was to characterize PD-L1 expression in thymomas and to determine correl...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Guleria P,Husain N,Shukla S,Kumar S,Parshad R,Jain D

    更新日期:2018-06-01 00:00:00

  • The complementary role of insulin-like growth factor II mRNA-binding protein 3 (IMP3) in diagnosis of Hodgkin's lymphoma.

    abstract:BACKGROUND:Hodgkin's Lymphoma (HL) is a peculiar subtype of lymphoid malignancies. The etiology of HL is still unknown. Insulin-like growth factor II mRNA-binding Protein 3 (IMP3) is a member of IMP family. In HL, IMP3 is expressed in the cytoplasmic compartment of the tumor cells (in both HRS cells & LP cells) against...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Masoud R,Ibrahiem A,Tantawy D,Eldosoky I

    更新日期:2019-10-01 00:00:00

  • Non-small cell lung carcinomas with CTNNB1 (beta-catenin) mutations: A clinicopathological study of 26 cases.

    abstract::Beta-catenin, encoded by the CTNNB1 gene, plays an important role in cell proliferation. Mutations of CTNNB1 are oncogenic in several tumor types and are often associated with a nuclear abnormal expression. However, such mutations have only rarely been reported in non-small cell lung carcinomas and their clinical sign...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Thomas de Montpréville V,Lacroix L,Rouleau E,Mamodaly M,Leclerc J,Tutuianu L,Planchard D,Boulate D,Mercier O,Besse B,Fadel É,Ghigna MR

    更新日期:2020-06-01 00:00:00

  • Angiosarcoma of the uterus: report of 2 new cases with deviant clinicopathologic features and review of the literature.

    abstract::A few cases of uterine angiosarcoma have been detailed in the literature: 2 new cases are herein described featuring some unusual clinical or phenotypic differences compared with previously published cases, such as occurrence in premenopausal age or a poorly differentiated histology. The patients were 35 and 81 years ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Cardinale L,Mirra M,Galli C,Goldblum JR,Pizzolitto S,Falconieri G

    更新日期:2008-06-01 00:00:00

  • Frozen section discrepancy in the evaluation of nonneoplastic central nervous system samples.

    abstract::Frozen section (FS) for intraoperative evaluation of central nervous system (CNS) lesions provides the neurosurgeon with a rapid preliminary pathologic diagnosis. Diagnosis of nonneoplastic lesions is particularly challenging in this venue. To highlight common diagnostic pitfalls, we sought to identify discrepancies b...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Plesec TP,Prayson RA

    更新日期:2009-12-01 00:00:00

  • Alveolar soft part sarcoma of the tongue: report of an unusual pattern in a child.

    abstract::A case of an unusual, primary alveolar soft part sarcoma of the tongue in a 3-year-old boy is presented. Alveolar soft part sarcoma is a rare malignant tumor that presents more frequently in the head and neck region of infants and children. To date, only six cases of lingual alveolar soft part sarcoma presenting in th...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Castle JT,Goode RK

    更新日期:1999-10-01 00:00:00

  • Clear cell renal cell carcinoma with focal renal angiomyoadenomatous tumor-like area.

    abstract::Recently, renal angiomyoadenomatous tumor (RAT) has been identified. However, there are no descriptions about clear cell renal cell carcinoma (RCC) with focal RAT-like features. A 33-year-old Japanese man was found to have a tumor in the left kidney. Macroscopically, the tumor extended into the perinephric fat tissue,...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Kuroda N,Hosokawa T,Michal M,Hes O,Sima R,Ohe C,Lee GH

    更新日期:2011-06-01 00:00:00

  • Plexiform leiomyoma of the esophagus: a complex radiographic, pathologic and endoscopic diagnosis.

    abstract::Radiographic identification of an abnormal lesion in the esophagus routinely occurs during workup of patients with symptomatic dysphagia. Leiomyoma is the most common benign finding; however, plexiform leiomyoma, a distinctive but rare variant, follows an unusual pattern of growth which can be a challenging surgical r...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Jaroszewski DE,Lam-Himlin D,Gruden J,Lidner TK,Etxebarria AA,De Petris G

    更新日期:2011-10-01 00:00:00

  • Correlation of anal cytology with follow-up histology and Human Papillomavirus genotyping: A 10-year experience from an academic medical center.

    abstract:BACKGROUND:Anal cytology (AC) is accepted as a practical screening modality for anal cancer. However, studies suggest that AC and anal biopsy dysplasia correlation is less robust than in cervicovaginal specimens. The current study goals were to look at our institutional experience in a subset of ACs and correlate with ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Hopp AM,Pant M,Sniedze S,Parsons LN,Hunt B,Giorgadze T

    更新日期:2020-11-20 00:00:00

  • A case of clear cell variant of solid-pseudopapillary tumor of the pancreas in an adult male patient.

    abstract::A clear cell variant of solid-pseudopapillary tumor (SPT) of the pancreas was initially reported in 2006 as a tumor that arose in the pancreatic body and tail in young adults; to date, only 4 cases of this entity have been reported. Here, we present the case of a 58-year-old man with clear cell variant of SPT with dis...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Tanino M,Kohsaka S,Kimura T,Tabu K,Nishihara H,Sawa H,Kawami H,Kamada H,Shimizu M,Tanaka S

    更新日期:2012-04-01 00:00:00

  • Aberrant keratin expression is common in primary hepatic malignant vascular tumors: A potential diagnostic pitfall.

    abstract::Malignant vascular neoplasms such as epithelioid hemangioendothelioma (EHE) and angiosarcoma (AS) can arise within the liver. The aim of this study was to study the expression of keratins CK7, AE1/AE3 and OSCAR in primary hepatic EHE and AS. 9 cases of hepatic EHE and 13 cases of hepatic AS were stained with ERG, CK7,...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Lee HE,Torbenson MS,Wu TT,Chandan VS

    更新日期:2020-12-01 00:00:00

  • Primary chondrosarcoma of ethmoid bone in a 6-year-old child.

    abstract::Chondrosarcoma (CS) is a distinctly uncommon tumor in young patients and tends to be located in the extremities. Cartilaginous tumors in young patients are benign tumors. We report a case of a childhood CS in a 6-year-old boy who presented with right-sided proptosis. Radiological examination revealed a large destructi...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Mahesha V,Goyal R,Vaiphei K,Nada R,Gupta AK

    更新日期:2006-06-01 00:00:00

  • Correlation of expression of hormone and HER2 receptors with various clinico-pathological prognostic parameters and with each other in malignant breast lesion.

    abstract:BACKGROUND:Estrogen receptors (ER), progesterone receptors (PR) and the human epidermal growth factor receptor-2 (HER2) are basic breast cancer molecular markers that are also best recognized prognostic factors and predictors of type of targeted therapy to be given. The objectives are to study the correlation of expres...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Mohanty SS

    更新日期:2020-11-05 00:00:00

  • Metastatic vs primary malignant neoplasms affecting the umbilicus: clinicopathologic features of 77 tumors.

    abstract::Periumbilical skin is unique due to its proximity to intra-abdominal and pelvic structures. In addition to primary skin malignancies, it is a site often involved with metastatic disease. We reviewed the clinical and pathologic features of 77 umbilical malignancies occurring at our institution since 1988. Seventy-seven...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Papalas JA,Selim MA

    更新日期:2011-08-01 00:00:00